Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (Rattus norvegicus (Rat)) | BDBM50214001 (CHEMBL389494 | N-(4-((1-(2-fluorobenzyl)-3-(cyclop...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.17E+3 | n/a | n/a | n/a | n/a |
Roche Research Center Curated by ChEMBL | Assay Description Inhibition of cPEPCK in rat H4IIE cells assessed as effect on glucose production | Bioorg Med Chem Lett 17: 3835-9 (2007) Article DOI: 10.1016/j.bmcl.2007.05.013 BindingDB Entry DOI: 10.7270/Q2BV7HF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (Rattus norvegicus (Rat)) | BDBM50214012 (CHEMBL394368 | N-(4-((1-(2-fluorobenzyl)-3-(cyclop...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a |
Roche Research Center Curated by ChEMBL | Assay Description Inhibition of cPEPCK in rat H4IIE cells assessed as effect on glucose production | Bioorg Med Chem Lett 17: 3835-9 (2007) Article DOI: 10.1016/j.bmcl.2007.05.013 BindingDB Entry DOI: 10.7270/Q2BV7HF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (Rattus norvegicus (Rat)) | BDBM50214004 (CHEMBL243116 | N-(4-((1-(2-fluorobenzyl)-3-butyl-2...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.97E+3 | n/a | n/a | n/a | n/a |
Roche Research Center Curated by ChEMBL | Assay Description Inhibition of cPEPCK in rat H4IIE cells assessed as effect on glucose production | Bioorg Med Chem Lett 17: 3835-9 (2007) Article DOI: 10.1016/j.bmcl.2007.05.013 BindingDB Entry DOI: 10.7270/Q2BV7HF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (Rattus norvegicus (Rat)) | BDBM50214010 (CHEMBL244165 | N-(4-((1-(2-fluorobenzyl)-3-(cyclop...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 4.70E+3 | n/a | n/a | n/a | n/a |
Roche Research Center Curated by ChEMBL | Assay Description Inhibition of cPEPCK in rat H4IIE cells assessed as effect on glucose production | Bioorg Med Chem Lett 17: 3835-9 (2007) Article DOI: 10.1016/j.bmcl.2007.05.013 BindingDB Entry DOI: 10.7270/Q2BV7HF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (Rattus norvegicus (Rat)) | BDBM50214013 (CHEMBL242486 | N-(4-((1-(2-fluorobenzyl)-3-(cyclop...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a |
Roche Research Center Curated by ChEMBL | Assay Description Inhibition of cPEPCK in rat H4IIE cells assessed as effect on glucose production | Bioorg Med Chem Lett 17: 3835-9 (2007) Article DOI: 10.1016/j.bmcl.2007.05.013 BindingDB Entry DOI: 10.7270/Q2BV7HF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (Rattus norvegicus (Rat)) | BDBM50214007 (CHEMBL394621 | N-(4-((1-(2-fluorobenzyl)-3-(cyclop...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 5.57E+3 | n/a | n/a | n/a | n/a |
Roche Research Center Curated by ChEMBL | Assay Description Inhibition of cPEPCK in rat H4IIE cells assessed as effect on glucose production | Bioorg Med Chem Lett 17: 3835-9 (2007) Article DOI: 10.1016/j.bmcl.2007.05.013 BindingDB Entry DOI: 10.7270/Q2BV7HF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (Rattus norvegicus (Rat)) | BDBM50214016 (CHEMBL243342 | N-(4-((1-(2-fluorobenzyl)-3-(cyclop...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 8.20E+3 | n/a | n/a | n/a | n/a |
Roche Research Center Curated by ChEMBL | Assay Description Inhibition of cPEPCK in rat H4IIE cells assessed as effect on glucose production | Bioorg Med Chem Lett 17: 3835-9 (2007) Article DOI: 10.1016/j.bmcl.2007.05.013 BindingDB Entry DOI: 10.7270/Q2BV7HF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (Rattus norvegicus (Rat)) | BDBM50133801 (CHEMBL120708 | N-(4-((1-(2-fluorobenzyl)-3-butyl-2...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | 8.60E+3 | n/a | n/a | n/a | n/a |
Roche Research Center Curated by ChEMBL | Assay Description Inhibition of cPEPCK in rat H4IIE cells assessed as effect on glucose production | Bioorg Med Chem Lett 17: 3835-9 (2007) Article DOI: 10.1016/j.bmcl.2007.05.013 BindingDB Entry DOI: 10.7270/Q2BV7HF1 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (Rattus norvegicus (Rat)) | BDBM50214003 (CHEMBL243134 | N-(4-((1-(2-fluorobenzyl)-3-(cyclop...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 8.75E+3 | n/a | n/a | n/a | n/a |
Roche Research Center Curated by ChEMBL | Assay Description Inhibition of cPEPCK in rat H4IIE cells assessed as effect on glucose production | Bioorg Med Chem Lett 17: 3835-9 (2007) Article DOI: 10.1016/j.bmcl.2007.05.013 BindingDB Entry DOI: 10.7270/Q2BV7HF1 | |||||||||||
More data for this Ligand-Target Pair |