Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM50539763 (Adagrasib | Mrtx-849 | Mrtx849) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1039/d2md00216g BindingDB Entry DOI: 10.7270/Q2DF6W53 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530357 (WO2022064009, Compound 136 | WO2022064009, Compoun...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 1.38 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530269 (WO2022064009, Compound 13) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 1.41 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530396 (WO2022064009, Compound 173) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 1.66 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530309 (WO2022064009, Compound 70) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 1.78 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530370 (WO2022064009, Compound 180a) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 2.09 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530318 (WO2022064009, Compound 82 | WO2022064009, Compound...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 2.14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530249 (WO2022064009, Compound 5) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 2.14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530318 (WO2022064009, Compound 82 | WO2022064009, Compound...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 2.14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530297 (WO2022064009, Compound 58) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 2.34 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530245 (WO2022064009, Compound 1 | WO2022064009, Compound ...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 2.45 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530266 (WO2022064009, Compound 154 | WO2022064009, Compoun...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 2.51 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530260 (WO2022064009, Compound 37) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 2.51 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530397 (WO2022064009, Compound 174) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 2.63 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530383 (WO2022064009, Compound 160) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 2.63 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530308 (WO2022064009, Compound 69) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 2.69 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530252 (WO2022064009, Compound 8) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 2.69 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530305 (WO2022064009, Compound 66) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 2.75 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530280 (WO2022064009, Compound 29) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 2.82 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530401 (WO2022064009, Compound 188) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 2.82 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530310 (WO2022064009, Compound 71) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 2.88 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM50363196 (CHEMBL1944698) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Nebraska Medical Center Curated by ChEMBL | Assay Description Inhibition of recombinant human full length C-terminal His6-tagged CDK7/cyclin H/N-terminal GST-tagged MAT1 expressed in baculovirus infected Sf21 in... | J Med Chem 59: 8667-8684 (2016) Article DOI: 10.1021/acs.jmedchem.6b00150 BindingDB Entry DOI: 10.7270/Q2G73GP8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530335 (WO2022064009, Compound 120 | WO2022064009, Compoun...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 3.02 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530369 (WO2022064009, Compound 150) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 3.16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530356 (WO2022064009, Compound 134) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 3.16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530337 (WO2022064009, Compound 122b) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 3.16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530286 (WO2022064009, Compound 156 | WO2022064009, Compoun...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 3.24 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530256 (WO2022064009, Compound 12) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 3.24 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530424 (WO2022064009, Compound 210) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 3.31 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530423 (WO2022064009, Compound 209) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 3.31 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530299 (WO2022064009, Compound 60) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 3.55 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530354 (WO2022064009, Compound 132) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 3.63 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530339 (WO2022064009, Compound 126) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 3.72 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530250 (WO2022064009, Compound 6) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530316 (WO2022064009, Compound 78) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 4.27 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530377 (WO2022064009, Compound 152) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 4.37 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530251 (WO2022064009, Compound 7) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 4.47 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530301 (WO2022064009, Compound 62 | WO2022064009, Compound...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 4.68 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530426 (WO2022064009, Compound 212) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 4.79 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530408 (WO2022064009, Compound 195b) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530342 (WO2022064009, Compound 129) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530247 (WO2022064009, Compound 3) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 5.01 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530262 (WO2022064009, Compound 39) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 5.01 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530286 (WO2022064009, Compound 156 | WO2022064009, Compoun...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 5.01 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530293 (WO2022064009, Compound 54) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 5.13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530298 (WO2022064009, Compound 59) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 5.25 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530410 (WO2022064009, Compound 199) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 5.37 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530414 (WO2022064009, Compound 203) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 5.37 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530312 (WO2022064009, Compound 73) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 5.75 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM530394 (WO2022064009, Compound 171a) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022064009 | n/a | n/a | 5.75 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B | |||||||||||
More data for this Ligand-Target Pair |
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