Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7' and Ligand = 'BDBM530245'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530245 (WO2022064009, Compound 1 | WO2022064009, Compound ...) Show SMILES C[C@@H]1Cc2cnc(NCc3ccn(C)n3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	2.45	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530245 (WO2022064009, Compound 1 | WO2022064009, Compound ...) Show SMILES C[C@@H]1Cc2cnc(NCc3ccn(C)n3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	8.32	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530245 (WO2022064009, Compound 1 | WO2022064009, Compound ...) Show SMILES C[C@@H]1Cc2cnc(NCc3ccn(C)n3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	9.77	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Compounds with potencies approaching the limit o...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530245 (WO2022064009, Compound 1 | WO2022064009, Compound ...) Show SMILES C[C@@H]1Cc2cnc(NCc3ccn(C)n3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Compounds with potencies approaching the limit o...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair