Compile Data Set for Download or QSAR

Found 120 hits of ic50 for UniProtKB: P11802   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM515983 (US11053238, Com. EX. 6) Show SMILES CC1(C)CCCc2nc3c(F)cc(cc3n12)-c1nc(Nc2ccc(CN3CCNCC3)cn2)ncc1F Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2959MRV
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM515951 (US11053238, Com. EX. 5) Show SMILES CC1(C)CCCc2nc3c(F)cc(cc3n12)-c1nc(Nc2ccc(cn2)N2CCN(CC2)C2COC2)ncc1F Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2959MRV
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM50110183 (Abemaciclib | LY-2835219 | US10626107, Example LY2...) Show SMILES CCN1CCN(Cc2ccc(Nc3ncc(F)c(n3)-c3cc(F)c4nc(C)n(C(C)C)c4c3)nc2)CC1 Show InChI InChI=1S/C27H32F2N8/c1-5-35-8-10-36(11-9-35)16-19-6-7-24(30-14-19)33-27-31-15-22(29)25(34-27)20-12-21(28)26-23(13-20)37(17(2)3)18(4)32-26/h6-7,12-15,17H,5,8-11,16H2,1-4H3,(H,30,31,33,34)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	PDB US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2959MRV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM516039 (US11053238, Compound 2a | US11053238, Compound 2b) Show SMILES CN1CCN(CC1)c1ccc(Nc2ncc(F)c(n2)-c2cc(F)c3nc4CCCCn4c3c2)nc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2959MRV
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM50110183 (Abemaciclib | LY-2835219 | US10626107, Example LY2...) Show SMILES CCN1CCN(Cc2ccc(Nc3ncc(F)c(n3)-c3cc(F)c4nc(C)n(C(C)C)c4c3)nc2)CC1 Show InChI InChI=1S/C27H32F2N8/c1-5-35-8-10-36(11-9-35)16-19-6-7-24(30-14-19)33-27-31-15-22(29)25(34-27)20-12-21(28)26-23(13-20)37(17(2)3)18(4)32-26/h6-7,12-15,17H,5,8-11,16H2,1-4H3,(H,30,31,33,34)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	PDB US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2959MRV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM515904 (4-(6-fluoro-1- methyl-1,2,3,4- tetrahydrobenzo[4,5...) Show SMILES CC1CCCc2nc3c(F)cc(cc3n12)-c1ccnc(Nc2ccc(cn2)N2CCN(C)CC2)n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2959MRV
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM516275 (US11053238, Compound 15b) Show SMILES C[C@H]1COCc2nc3c(F)cc(cc3n12)-c1nc(Nc2ccc(cn2)N2CCN(C)CC2)ncc1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2959MRV
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM516028 (US11053238, Compound 1a | US11053238, Compound 1b) Show SMILES CN1CCN(CC1)c1ccc(Nc2ncc(F)c(n2)-c2cc(F)c3nc4CCCC5(CC5)n4c3c2)nc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2959MRV
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM515904 (4-(6-fluoro-1- methyl-1,2,3,4- tetrahydrobenzo[4,5...) Show SMILES CC1CCCc2nc3c(F)cc(cc3n12)-c1ccnc(Nc2ccc(cn2)N2CCN(C)CC2)n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2959MRV
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM515905 (N-(5-((4-ethylpiperazin- 1-yl)methyl) pyridin-2-yl...) Show SMILES CCN1CCN(Cc2ccc(Nc3ncc(F)c(n3)-c3cc(F)c4nc5CCCC(C)n5c4c3)nc2)CC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2959MRV
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM515923 (US11053238, Compound 16b | US11053238, Example 16b) Show SMILES CCN1CCN(Cc2ccc(Nc3ncc(F)c(n3)-c3cc(F)c4nc5COC[C@H](C)n5c4c3)nc2)CC1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2959MRV
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM515923 (US11053238, Compound 16b | US11053238, Example 16b) Show SMILES CCN1CCN(Cc2ccc(Nc3ncc(F)c(n3)-c3cc(F)c4nc5COC[C@H](C)n5c4c3)nc2)CC1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2959MRV
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM516039 (US11053238, Compound 2a | US11053238, Compound 2b) Show SMILES CN1CCN(CC1)c1ccc(Nc2ncc(F)c(n2)-c2cc(F)c3nc4CCCCn4c3c2)nc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	108	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2959MRV
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM515986 (US11053238, Com. EX. No. 7) Show SMILES CC1CCCn2c1nc1c(F)cc(cc21)-c1ccnc(Nc2ccc(cn2)N2CCN(C)CC2)n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2959MRV
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM516028 (US11053238, Compound 1a | US11053238, Compound 1b) Show SMILES CN1CCN(CC1)c1ccc(Nc2ncc(F)c(n2)-c2cc(F)c3nc4CCCC5(CC5)n4c3c2)nc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	121	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2959MRV
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648803 (8-(2,2-difluoro-6-azaspiro[3.4]octan-6-yl)-N-(1- (...) Show SMILES CS(=O)(=O)N1CCC(CC1)Nc1ncc2ccnc(N3CCC4(CC(F)(F)C4)C3)c2n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648804 (8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-N-(1- ...) Show SMILES CS(=O)(=O)N1CCC(CC1)Nc1ncc2ccnc(N3CCC4(CC4(F)F)C3)c2n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648806 (3-cyclopropyl-1-(2-((1-(methylsulfonyl)piperidin- ...) Show SMILES CS(=O)(=O)N1CCC(CC1)Nc1ncc2ccnc(N3CCC(C3)(C#N)C3CC3)c2n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648807 (8-(2,2-difluoro-6-azaspiro[3.4]octan-6-yl)-N-(5-(6...) Show SMILES CCN1CC2(C1)CN(C2)c1ccc(Nc2ncc3ccnc(N4CCC5(CC(F)(F)C5)C4)c3n2)nc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648808 (N-(1-(methylsulfonyl)piperidin-4-yl)-8-(8-oxa-2- a...) Show SMILES CS(=O)(=O)N1CCC(CC1)Nc1ncc2ccnc(N3CCC4(C3)CCOCC4)c2n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648811 (8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-N-(5- ...) Show SMILES CN1CCn2nc(Nc3ncc4ccnc(N5CCC6(CC6(F)F)C5)c4n3)cc2C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648812 (8-(8,8-difluoro-2-(methyl-d3)-2,6- diazaspiro[3.4]...) Show SMILES CN1CC2(C1)CN(CC2(F)F)c1nc(C)cc2cnc(NC3CCN(CC3)S(=O)(=O)c3cnn(C)c3)nc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648813 (8-(8,8-difluoro-2-(methyl-d3)-2,6- diazaspiro[3.4]...) Show SMILES CN1CC2(C1)CN(CC2(F)F)c1nc(C)cc2cnc(NC3CCN(CC3)S(C)(=O)=O)nc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648814 (N-(1-(cyclopropylsulfonyl)piperidin-4-yl)-8-(8,8- ...) Show SMILES CN1CC2(C1)CN(CC2(F)F)c1nc(C)cc2cnc(NC3CCN(CC3)S(=O)(=O)C3CC3)nc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648815 (8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-N-(1- ...) Show SMILES CS(=O)(=O)N1CC(C1)Nc1ncc2ccnc(N3CCC4(CC4(F)F)C3)c2n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648817 ((3aR,8bR)-2-(2-((1-(methylsulfonyl)piperidin-4- yl...) Show SMILES CS(=O)(=O)N1CCC(CC1)Nc1ncc2ccnc(C3C[C@@H]4[C@H](C3)S(=O)(=O)c3ccccc43)c2n1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648818 (8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-N- ((1...) Show SMILES CN1C[C@H]2[C@@H](C1)[C@@H]2Nc1ncc2ccnc(N3CCC4(CC4(F)F)C3)c2n1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648821 (8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-N-(1- ...) Show SMILES CN1CCC(CC1)n1cc(Nc2ncc3ccnc(N4CCC5(CC5(F)F)C4)c3n2)cn1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648822 (8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-N-(5- ...) Show SMILES CCN1CC2(C1)CN(C2)c1ccc(Nc2ncc3ccnc(N4CCC5(CC5(F)F)C4)c3n2)nc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648823 (8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-N-(2- ...) Show SMILES CN1Cc2ccc(Nc3ncc4ccnc(N5CCC6(CC6(F)F)C5)c4n3)nc2C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648824 (N-(2-methylisoindolin-5-yl)-8-(7- (methylsulfonyl)...) Show SMILES CN1Cc2ccc(Nc3ncc4ccnc(N5CCC6(CCN(C6)S(C)(=O)=O)C5)c4n3)cc2C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648825 (6-(2-((2-methylisoindolin-5-yl)amino)pyrido[3,4- d...) Show SMILES CN1Cc2ccc(Nc3ncc4ccnc(N5CC6(C5)CS(=O)(=O)C6)c4n3)cc2C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648826 (N-(1-(cyclopropylsulfonyl)piperidin-4-yl)-6- methy...) Show SMILES Cc1cc2cnc(NC3CCN(CC3)S(=O)(=O)C3CC3)nc2c(n1)N1CC2(C1)CCNC2 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648829 (3-cyclopropyl-1-(6-methyl-2-((4-(6-methyl-2,6- dia...) Show SMILES CN1CC2(C1)CN(C2)c1ccc(Nc2ncc3cc(C)nc(N4CCC(C4)(C#N)C4CC4)c3n2)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648834 (N-(1-(cyclopropylsulfonyl)piperidin-4-yl)-6- methy...) Show SMILES Cc1cc2cnc(NC3CCN(CC3)S(=O)(=O)C3CC3)nc2c(n1)N1CC2(CNC2)C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648835 (8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-6- met...) Show SMILES CN1CC2(CC(C2)n2cc(Nc3ncc4cc(C)nc(N5CCC6(CC6(F)F)C5)c4n3)cn2)C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648836 (8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-6- met...) Show SMILES CN1CC2(C1)CN(C2)c1ccc(Nc2ncc3cc(C)nc(N4CCC5(CC5(F)F)C4)c3n2)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648837 (6-methyl-N-(4-(6-methyl-2,6- diazaspiro[3.3]heptan...) Show SMILES CN1CC2(C1)CN(C2)c1ccc(Nc2ncc3cc(C)nc(N4CCC5(C4)CCOCC5)c3n2)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648842 (8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-N- ((1...) Show SMILES CN(C)C[C@H]1CC[C@@H](CC1)Nc1ncc2cc(C)nc(N3CCC4(CC4(F)F)C3)c2n1 |r,wU:7.10,wD:4.3,(-8.46,-4.26,;-7.13,-3.49,;-7.13,-1.95,;-5.79,-4.26,;-4.46,-3.49,;-3.13,-4.26,;-1.79,-3.49,;-1.79,-1.95,;-3.13,-1.18,;-4.46,-1.95,;-.46,-1.18,;.88,-1.95,;.88,-3.49,;2.21,-4.26,;3.54,-3.49,;4.88,-4.26,;6.21,-3.49,;7.54,-4.26,;6.21,-1.95,;4.88,-1.18,;4.88,.36,;3.63,1.26,;4.11,2.73,;5.65,2.73,;5.81,4.26,;7.05,3.36,;8.3,2.45,;8.46,3.98,;6.12,1.26,;3.54,-1.95,;2.21,-1.18,)| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648843 (8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-6- met...) Show SMILES Cc1cc2cnc(NC3CCC(CC3)S(C)(=O)=O)nc2c(n1)N1CCC2(CC2(F)F)C1 |(6.88,-3.59,;5.54,-2.82,;4.21,-3.59,;2.88,-2.82,;1.54,-3.59,;.21,-2.82,;.21,-1.28,;-1.13,-.51,;-2.46,-1.28,;-3.79,-.51,;-5.13,-1.28,;-5.13,-2.82,;-3.79,-3.59,;-2.46,-2.82,;-6.46,-3.59,;-7.79,-4.36,;-7.23,-2.26,;-5.69,-4.93,;1.54,-.51,;2.88,-1.28,;4.21,-.51,;5.54,-1.28,;4.21,1.03,;2.96,1.93,;3.44,3.4,;4.98,3.4,;5.14,4.93,;6.39,4.02,;7.63,3.12,;7.79,4.65,;5.46,1.93,)| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648852 (1-(cyclopropanesulfonyl)-N-(8-{2,6- diazaspiro[3.4...) Show SMILES FC(F)c1cc2cnc(NC3CCN(CC3)S(=O)(=O)C3CC3)nc2c(n1)N1CC2(C1)CCNC2 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648853 (N-(2-cyclopropylisoindolin-5-yl)-6-methyl-8-(2,6- ...) Show SMILES Cc1cc2cnc(Nc3ccc4CN(Cc4c3)C3CC3)nc2c(n1)N1CC2(C1)CCNC2 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648856 (N-(2-cyclopropylisoindolin-5-yl)-6- (difluoromethy...) Show SMILES FC(F)c1cc2cnc(Nc3ccc4CN(Cc4c3)C3CC3)nc2c(n1)N1CC2(C1)CCNC2 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648858 (8-(1,1-difluoro-6-azaspiro[3.4]octan-6-yl)-6- meth...) Show SMILES Cc1cc2cnc(NC3CCN(CC3)S(C)(=O)=O)nc2c(n1)N1CCC2(CCC2(F)F)C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648859 (8-(2,2-difluoro-6-azaspiro[3.4]octan-6-yl)-6- meth...) Show SMILES Cc1cc2cnc(NC3CCN(CC3)S(C)(=O)=O)nc2c(n1)N1CCC2(CC(F)(F)C2)C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648860 (6-methyl-N-(1-(methylsulfonyl)piperidin-4-yl)-8- (...) Show SMILES Cc1cc2cnc(NC3CCN(CC3)S(C)(=O)=O)nc2c(n1)N1CCC2(CC2)C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648861 (N-(1-((cyclobutylmethyl)sulfonyl)piperidin-4-yl)- ...) Show SMILES FC(F)c1cc2cnc(NC3CCN(CC3)S(=O)(=O)CC3CCC3)nc2c(n1)N1CC2(C1)CCNC2 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648862 (3-cyclopropyl-1-(2-((1- (cyclopropylsulfonyl)piper...) Show SMILES Cc1cc2cnc(NC3CCN(CC3)S(=O)(=O)C3CC3)nc2c(n1)N1CC(O)(C1)C1CC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648863 (8-(3-cyclopropoxyazetidin-1-yl)-N-(1- (cyclopropyl...) Show SMILES Cc1cc2cnc(NC3CCN(CC3)S(=O)(=O)C3CC3)nc2c(n1)N1CC(C1)OC1CC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/6 (Homo sapiens (Human))	BDBM648864 (N-(1-(cyclopropylsulfonyl)piperidin-4-yl)-8-(3- (d...) Show SMILES Cc1cc2cnc(NC3CCN(CC3)S(=O)(=O)C3CC3)nc2c(n1)N1CCC(C1)OC(F)F Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair

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