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Compile Data Set for Download or QSAR

Found 3 hits of ic50 for monomerid = 241619   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential M8 protein


(Canis lupus familiaris (Dog))
BDBM241619
PNG
(US9409915, 11 | US9718820, Compound 11)
Show SMILES COc1nc(cc2nc([nH]c12)-c1c(Cl)c(nn1C)C(C)(C)C)-c1ccccc1Cl
Show InChI InChI=1S/C21H21Cl2N5O/c1-21(2,3)18-15(23)17(28(4)27-18)19-24-14-10-13(11-8-6-7-9-12(11)22)25-20(29-5)16(14)26-19/h6-10H,1-5H3,(H,24,26)
PDB

KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.5n/an/an/an/an/a37



Janssen Pharmaceutica NV

US Patent


Assay Description
HEK293 cells stably expressing canine TRPM8 were routinely grown as monolayers in Dulbecco's minimum essential medium supplemented with 10% FBS, 2 mM...


US Patent US9409915 (2016)


BindingDB Entry DOI: 10.7270/Q23J3BVJ
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8


(Homo sapiens (Human))
BDBM241619
PNG
(US9409915, 11 | US9718820, Compound 11)
Show SMILES COc1nc(cc2nc([nH]c12)-c1c(Cl)c(nn1C)C(C)(C)C)-c1ccccc1Cl
Show InChI InChI=1S/C21H21Cl2N5O/c1-21(2,3)18-15(23)17(28(4)27-18)19-24-14-10-13(11-8-6-7-9-12(11)22)25-20(29-5)16(14)26-19/h6-10H,1-5H3,(H,24,26)
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 3.5n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Transient receptor potential M8 protein


(Canis lupus familiaris (Dog))
BDBM241619
PNG
(US9409915, 11 | US9718820, Compound 11)
Show SMILES COc1nc(cc2nc([nH]c12)-c1c(Cl)c(nn1C)C(C)(C)C)-c1ccccc1Cl
Show InChI InChI=1S/C21H21Cl2N5O/c1-21(2,3)18-15(23)17(28(4)27-18)19-24-14-10-13(11-8-6-7-9-12(11)22)25-20(29-5)16(14)26-19/h6-10H,1-5H3,(H,24,26)
PDB

KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.5n/an/an/an/an/a25



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
HEK293 cells stably expressing canine TRPM8 were routinely grown as monolayers in Dulbecco's minimum essential medium supplemented with 10% FBS, ...


US Patent US9718820 (2017)


BindingDB Entry DOI: 10.7270/Q2RV0QQ5
More data for this
Ligand-Target Pair