Compile Data Set for Download or QSAR

Found 4 hits of ic50 for monomerid = 380783   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor [T790M,L858R] (Homo sapiens (Human))	BDBM380783 (N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-met...) Show SMILES COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nc(-c2cnn(C)c2)c2cc[nH]c2n1 Show InChI InChI=1S/C25H31N9O2/c1-7-22(35)28-18-12-19(21(36-6)13-20(18)33(4)11-10-32(2)3)29-25-30-23(16-14-27-34(5)15-16)17-8-9-26-24(17)31-25/h7-9,12-15H,1,10-11H2,2-6H3,(H,28,35)(H2,26,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description The inhibitory activities on T790M/L858R double mutant EGFR kinase (Invitrogen, PV4879) and wild-type EGFR kinase (Invitrogen, PV3872) were determine...				J Med Chem 51: 1706-18 (2008) BindingDB Entry DOI: 10.7270/Q2PV6NPJ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [T790M,L858R] (Homo sapiens (Human))	BDBM380783 (N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-met...) Show SMILES COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nc(-c2cnn(C)c2)c2cc[nH]c2n1 Show InChI InChI=1S/C25H31N9O2/c1-7-22(35)28-18-12-19(21(36-6)13-20(18)33(4)11-10-32(2)3)29-25-30-23(16-14-27-34(5)15-16)17-8-9-26-24(17)31-25/h7-9,12-15H,1,10-11H2,2-6H3,(H,28,35)(H2,26,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description The inhibitory activities on T790M/L858R double mutant EGFR kinase (Invitrogen, PV4879) and wild-type EGFR kinase (Invitrogen, PV3872) were determine...				J Med Chem 51: 1706-18 (2008) BindingDB Entry DOI: 10.7270/Q2PV6NPJ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM380783 (N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-met...) Show SMILES COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nc(-c2cnn(C)c2)c2cc[nH]c2n1 Show InChI InChI=1S/C25H31N9O2/c1-7-22(35)28-18-12-19(21(36-6)13-20(18)33(4)11-10-32(2)3)29-25-30-23(16-14-27-34(5)15-16)17-8-9-26-24(17)31-25/h7-9,12-15H,1,10-11H2,2-6H3,(H,28,35)(H2,26,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	393	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description The inhibitory activities on T790M/L858R double mutant EGFR kinase (Invitrogen, PV4879) and wild-type EGFR kinase (Invitrogen, PV3872) were determine...				J Med Chem 51: 1706-18 (2008) BindingDB Entry DOI: 10.7270/Q2PV6NPJ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM380783 (N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-met...) Show SMILES COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nc(-c2cnn(C)c2)c2cc[nH]c2n1 Show InChI InChI=1S/C25H31N9O2/c1-7-22(35)28-18-12-19(21(36-6)13-20(18)33(4)11-10-32(2)3)29-25-30-23(16-14-27-34(5)15-16)17-8-9-26-24(17)31-25/h7-9,12-15H,1,10-11H2,2-6H3,(H,28,35)(H2,26,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description The inhibitory activities on T790M/L858R double mutant EGFR kinase (Invitrogen, PV4879) and wild-type EGFR kinase (Invitrogen, PV3872) were determine...				J Med Chem 51: 1706-18 (2008) BindingDB Entry DOI: 10.7270/Q2PV6NPJ
					More data for this Ligand-Target Pair