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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50023533   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neutrophil elastase


(Homo sapiens (Human))		BDBM50023533
PNG
(CHEMBL10228 | Diphenyl-methanone-4,4'-di-(Carbonic...)
Show SMILES CC(C)(C)OC(=O)Oc1ccc(cc1)C(=O)c1ccc(OC(=O)OC(C)(C)C)cc1
Show InChI InChI=1S/C23H26O7/c1-22(2,3)29-20(25)27-17-11-7-15(8-12-17)19(24)16-9-13-18(14-10-16)28-21(26)30-23(4,5)6/h7-14H,1-6H3
PDB
MMDB

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n/an/a 900n/an/an/an/an/an/a



Searle Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against human leukocyte elastase at 10e-7 M

J Med Chem 31: 1052-61 (1988)


BindingDB Entry DOI: 10.7270/Q2PC31DJ
More data for this
Ligand-Target Pair