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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50179891   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50179891
PNG
((4-Chloro-3-trifluoromethylphenyl)-(4-isoquinolin-...)
Show SMILES FC(F)(F)c1cc(Nc2nnc(-c3cccc4cnccc34)c3ccccc23)ccc1Cl
Show InChI InChI=1S/C24H14ClF3N4/c25-21-9-8-15(12-20(21)24(26,27)28)30-23-19-6-2-1-5-18(19)22(31-32-23)17-7-3-4-14-13-29-11-10-16(14)17/h1-13H,(H,30,32)
PDB
MMDB

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PC cid
PC sid
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Article
PubMed
n/an/a 120n/an/an/an/an/an/a



ImClone Systems, Inc.

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) by HTRF method


Bioorg Med Chem 17: 731-40 (2009)


Article DOI: 10.1016/j.bmc.2008.11.049
BindingDB Entry DOI: 10.7270/Q2W95929
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50179891
PNG
((4-Chloro-3-trifluoromethylphenyl)-(4-isoquinolin-...)
Show SMILES FC(F)(F)c1cc(Nc2nnc(-c3cccc4cnccc34)c3ccccc23)ccc1Cl
Show InChI InChI=1S/C24H14ClF3N4/c25-21-9-8-15(12-20(21)24(26,27)28)30-23-19-6-2-1-5-18(19)22(31-32-23)17-7-3-4-14-13-29-11-10-16(14)17/h1-13H,(H,30,32)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 120n/an/an/an/an/an/a



ImClone Systems

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 by HTRF assay


Bioorg Med Chem Lett 16: 1579-81 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.045
BindingDB Entry DOI: 10.7270/Q2WS8SVC
More data for this
Ligand-Target Pair