BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50205814   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosinase


(Homo sapiens (Human))
BDBM50205814
PNG
(CHEMBL3898657)
Show SMILES Oc1cccc[n+]1[O-]
Show InChI InChI=1S/C5H5NO2/c7-5-3-1-2-4-6(5)8/h1-4,7H
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.50E+5n/an/an/an/an/an/a



Univ. Grenoble-Alpes/CNRS

Curated by ChEMBL


Assay Description
Inhibition of tyrosinase in human MNT1 cells assessed as suppression of melanin biosynthesis measured after 96 hrs


ACS Med Chem Lett 8: 55-60 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00369
BindingDB Entry DOI: 10.7270/Q24F1SQN
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))
BDBM50205814
PNG
(CHEMBL3898657)
Show SMILES Oc1cccc[n+]1[O-]
Show InChI InChI=1S/C5H5NO2/c7-5-3-1-2-4-6(5)8/h1-4,7H
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.30E+6n/an/an/an/an/an/a



Univ. Grenoble-Alpes/CNRS

Curated by ChEMBL


Assay Description
Inhibition of tyrosinase in human MNT1 cell lysate pretreated prior to addition of L-DOPA as substrate measured after 3 hrs


ACS Med Chem Lett 8: 55-60 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00369
BindingDB Entry DOI: 10.7270/Q24F1SQN
More data for this
Ligand-Target Pair