Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Tyrosinase' and Ligand = 'BDBM50205814'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosinase (Homo sapiens (Human))	BDBM50205814 (CHEMBL3898657) Show SMILES Oc1cccc[n+]1[O-] Show InChI InChI=1S/C5H5NO2/c7-5-3-1-2-4-6(5)8/h1-4,7H	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Univ. Grenoble-Alpes/CNRS Curated by ChEMBL					Assay Description Inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells assessed as diphenolase activity using L-DOPA as substrate by ...				ACS Med Chem Lett 8: 55-60 (2017) Article DOI: 10.1021/acsmedchemlett.6b00369 BindingDB Entry DOI: 10.7270/Q24F1SQN
					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50205814 (CHEMBL3898657) Show SMILES Oc1cccc[n+]1[O-] Show InChI InChI=1S/C5H5NO2/c7-5-3-1-2-4-6(5)8/h1-4,7H	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human tyrosinase				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50205814 (CHEMBL3898657) Show SMILES Oc1cccc[n+]1[O-] Show InChI InChI=1S/C5H5NO2/c7-5-3-1-2-4-6(5)8/h1-4,7H	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human tyrosinase				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50205814 (CHEMBL3898657) Show SMILES Oc1cccc[n+]1[O-] Show InChI InChI=1S/C5H5NO2/c7-5-3-1-2-4-6(5)8/h1-4,7H	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Univ. Grenoble-Alpes/CNRS Curated by ChEMBL					Assay Description Inhibition of tyrosinase in human MNT1 cells assessed as suppression of melanin biosynthesis measured after 96 hrs				ACS Med Chem Lett 8: 55-60 (2017) Article DOI: 10.1021/acsmedchemlett.6b00369 BindingDB Entry DOI: 10.7270/Q24F1SQN
					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50205814 (CHEMBL3898657) Show SMILES Oc1cccc[n+]1[O-] Show InChI InChI=1S/C5H5NO2/c7-5-3-1-2-4-6(5)8/h1-4,7H	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+6	n/a	n/a	n/a	n/a	n/a	n/a
Univ. Grenoble-Alpes/CNRS Curated by ChEMBL					Assay Description Inhibition of tyrosinase in human MNT1 cell lysate pretreated prior to addition of L-DOPA as substrate measured after 3 hrs				ACS Med Chem Lett 8: 55-60 (2017) Article DOI: 10.1021/acsmedchemlett.6b00369 BindingDB Entry DOI: 10.7270/Q24F1SQN
					More data for this Ligand-Target Pair