Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glycogen debranching enzyme (Oryctolagus cuniculus) | BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol | C...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University Curated by ChEMBL | Assay Description Inhibition of rabbit muscle amylo-1,6-glucosidase | Bioorg Med Chem 16: 7330-6 (2008) Article DOI: 10.1016/j.bmc.2008.06.026 BindingDB Entry DOI: 10.7270/Q27D2W2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ceramide glucosyltransferase (Mus musculus) | BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol | C...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores... | ACS Med Chem Lett 2: 519-522 (2011) Article DOI: 10.1021/ml200050s BindingDB Entry DOI: 10.7270/Q28916V8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase (Rattus norvegicus) | BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol | C...) | PDB Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University Curated by ChEMBL | Assay Description Concentration that causes 50% inhibition of mammalian lactase beta-galactosidase was determined in rat intestine | J Med Chem 37: 3701-6 (1994) BindingDB Entry DOI: 10.7270/Q2ZC83H3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sucrase-isomaltase, intestinal (Rattus norvegicus (Rat)) | BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol | C...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toyama Curated by ChEMBL | Assay Description Inhibition of rat intestinal sucrase assessed as production of p-nitrophenol at by spectrophotometry | Bioorg Med Chem 19: 3558-68 (2011) Article DOI: 10.1016/j.bmc.2011.04.011 BindingDB Entry DOI: 10.7270/Q2BC3ZWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sucrase-isomaltase, intestinal (Rattus norvegicus (Rat)) | BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol | C...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toyama Curated by ChEMBL | Assay Description Inhibition of rat intestinal isomaltase assessed as production of p-nitrophenol at by spectrophotometry | Bioorg Med Chem 19: 3558-68 (2011) Article DOI: 10.1016/j.bmc.2011.04.011 BindingDB Entry DOI: 10.7270/Q2BC3ZWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase (Bos taurus (Bovine)) | BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol | C...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 3.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University Curated by ChEMBL | Assay Description Concentration that causes 50% inhibition of mammalian cytosolic beta-galactosidase was determined in bovine liver | J Med Chem 37: 3701-6 (1994) BindingDB Entry DOI: 10.7270/Q2ZC83H3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase (Bos taurus (Bovine)) | BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol | C...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toyama Curated by ChEMBL | Assay Description Inhibition of bovine liver beta-galactosidase assessed as production of p-nitrophenol by spectrophotometry | Bioorg Med Chem 19: 3558-68 (2011) Article DOI: 10.1016/j.bmc.2011.04.011 BindingDB Entry DOI: 10.7270/Q2BC3ZWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sucrase-isomaltase, intestinal (Rattus norvegicus (Rat)) | BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol | C...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University Curated by ChEMBL | Assay Description Inhibition of Wistar rat intestinal isomaltase by glucose B-test | J Nat Prod 60: 312-4 (1997) Article DOI: 10.1021/np960646y BindingDB Entry DOI: 10.7270/Q2WQ03TX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sucrase-isomaltase, intestinal (Rattus norvegicus (Rat)) | BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol | C...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University Curated by ChEMBL | Assay Description Inhibition of rat intestinal brush border membrane sucrase | Bioorg Med Chem 16: 7330-6 (2008) Article DOI: 10.1016/j.bmc.2008.06.026 BindingDB Entry DOI: 10.7270/Q27D2W2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tissue alpha-L-fucosidase (Homo sapiens (Human)) | BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol | C...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University Curated by ChEMBL | Assay Description Concentration that causes 50% inhibition of mammalian alpha-L-fucosidase was determined in bovine epididymis | J Med Chem 37: 3701-6 (1994) BindingDB Entry DOI: 10.7270/Q2ZC83H3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal acid glucosylceramidase (Bos taurus) | BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol | C...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toyama Curated by ChEMBL | Assay Description Inhibition of bovine liver beta-glucosidase assessed as production of 4-methylumbelliferone using 4-methylumbelliferyl beta-D-glucoside as substrate ... | Bioorg Med Chem 19: 3558-68 (2011) Article DOI: 10.1016/j.bmc.2011.04.011 BindingDB Entry DOI: 10.7270/Q2BC3ZWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutral alpha-glucosidase C (Mus musculus) | BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol | C...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 4.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University Curated by ChEMBL | Assay Description Concentration that causes 50% inhibition of mammalian alpha-glucosidase (isomaltase) was determined in rat intestine | J Med Chem 37: 3701-6 (1994) BindingDB Entry DOI: 10.7270/Q2ZC83H3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sucrase-isomaltase, intestinal (Rattus norvegicus (Rat)) | BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol | C...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University Curated by ChEMBL | Assay Description Inhibition of rat intestinal brush border membrane isomaltase | Bioorg Med Chem 16: 7330-6 (2008) Article DOI: 10.1016/j.bmc.2008.06.026 BindingDB Entry DOI: 10.7270/Q27D2W2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Bos taurus) | BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol | C...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 5.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University Curated by ChEMBL | Assay Description Inhibition of mammalian alpha-glucosidase (lysosomal) was determined in bovine liver | J Med Chem 37: 3701-6 (1994) BindingDB Entry DOI: 10.7270/Q2ZC83H3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Rattus norvegicus) | BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol | C...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University Curated by ChEMBL | Assay Description Inhibition of rat intestinal brush border membrane maltase | Bioorg Med Chem 16: 7330-6 (2008) Article DOI: 10.1016/j.bmc.2008.06.026 BindingDB Entry DOI: 10.7270/Q27D2W2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Rattus norvegicus) | BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol | C...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 8.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University Curated by ChEMBL | Assay Description Concentration that causes 50% inhibition of mammalian alpha-glucosidase (maltase) was determined in rat intestine | J Med Chem 37: 3701-6 (1994) BindingDB Entry DOI: 10.7270/Q2ZC83H3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutral alpha-glucosidase AB (Homo sapiens (Human)) | BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol | C...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University Curated by ChEMBL | Assay Description Concentration that causes 50% inhibition of mammalian alpha-mannosidase (golgi II) was determined in rat liver | J Med Chem 37: 3701-6 (1994) BindingDB Entry DOI: 10.7270/Q2ZC83H3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Non-lysosomal glucosylceramidase (Homo sapiens (Human)) | BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol | C...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of glucosylceramidase 2 from spleen of patient with gaucher's disease by fluorimetric analysis | ACS Med Chem Lett 2: 519-522 (2011) Article DOI: 10.1021/ml200050s BindingDB Entry DOI: 10.7270/Q28916V8 | |||||||||||
More data for this Ligand-Target Pair |