Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Kinesin-like protein KIF11 (Homo sapiens (Human)) | BDBM50276289 (3'-fluoro-4'-(trifluoromethyl)biphenyl-4-sulfonami...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Shizuoka Curated by ChEMBL | Assay Description Inhibition of microtubule-stimulated recombinant Eg5 (unknown origin) assessed as inhibition ATP hydrolysis by luminescent kinase assay | Bioorg Med Chem Lett 19: 1058-61 (2009) Article DOI: 10.1016/j.bmcl.2009.01.018 BindingDB Entry DOI: 10.7270/Q20R9P8G | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |