Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
RNA-directed RNA polymerase (Hepatitis C virus) | BDBM50544636 (CHEMBL4632867) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 630 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen BioPharma, Inc. Curated by ChEMBL | Assay Description Inhibition of HCV NS5B RNA-dependent RNA polymerase activity assessed as reduction in radiolabeled ribonucleotide monophosphates incorporation into R... | J Med Chem 63: 10380-10395 (2020) Article DOI: 10.1021/acs.jmedchem.0c00935 BindingDB Entry DOI: 10.7270/Q2TM7FP8 | |||||||||||
More data for this Ligand-Target Pair |