Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tryptase beta-2 (Mus musculus) | BDBM50511189![]() (CHEMBL4571556) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 455 | n/a | n/a | n/a | n/a | n/a | n/a |
Weill Cornell Medicine Curated by ChEMBL | Assay Description Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi... | J Med Chem 63: 3004-3027 (2020) Article DOI: 10.1021/acs.jmedchem.9b01689 BindingDB Entry DOI: 10.7270/Q2N3018J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase beta-2 (Mus musculus) | BDBM50511187![]() (CHEMBL4542067) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 599 | n/a | n/a | n/a | n/a | n/a | n/a |
Weill Cornell Medicine Curated by ChEMBL | Assay Description Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi... | J Med Chem 63: 3004-3027 (2020) Article DOI: 10.1021/acs.jmedchem.9b01689 BindingDB Entry DOI: 10.7270/Q2N3018J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase beta-2 (Mus musculus) | BDBM50511190![]() (CHEMBL4592202) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Weill Cornell Medicine Curated by ChEMBL | Assay Description Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi... | J Med Chem 63: 3004-3027 (2020) Article DOI: 10.1021/acs.jmedchem.9b01689 BindingDB Entry DOI: 10.7270/Q2N3018J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase beta-2 (Mus musculus) | BDBM50511191![]() (CHEMBL4467543) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Weill Cornell Medicine Curated by ChEMBL | Assay Description Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi... | J Med Chem 63: 3004-3027 (2020) Article DOI: 10.1021/acs.jmedchem.9b01689 BindingDB Entry DOI: 10.7270/Q2N3018J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase beta-2 (Mus musculus) | BDBM50511179![]() (CHEMBL4453049) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.55E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Weill Cornell Medicine Curated by ChEMBL | Assay Description Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi... | J Med Chem 63: 3004-3027 (2020) Article DOI: 10.1021/acs.jmedchem.9b01689 BindingDB Entry DOI: 10.7270/Q2N3018J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase beta-2 (Mus musculus) | BDBM50511186![]() (CHEMBL4553079) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Weill Cornell Medicine Curated by ChEMBL | Assay Description Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi... | J Med Chem 63: 3004-3027 (2020) Article DOI: 10.1021/acs.jmedchem.9b01689 BindingDB Entry DOI: 10.7270/Q2N3018J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase beta-2 (Mus musculus) | BDBM50511181![]() (CHEMBL4464544) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Weill Cornell Medicine Curated by ChEMBL | Assay Description Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi... | J Med Chem 63: 3004-3027 (2020) Article DOI: 10.1021/acs.jmedchem.9b01689 BindingDB Entry DOI: 10.7270/Q2N3018J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase beta-2 (Mus musculus) | BDBM50511182![]() (CHEMBL4576109) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Weill Cornell Medicine Curated by ChEMBL | Assay Description Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi... | J Med Chem 63: 3004-3027 (2020) Article DOI: 10.1021/acs.jmedchem.9b01689 BindingDB Entry DOI: 10.7270/Q2N3018J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase beta-2 (Mus musculus) | BDBM50511180![]() (CHEMBL4548912) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.89E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Weill Cornell Medicine Curated by ChEMBL | Assay Description Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi... | J Med Chem 63: 3004-3027 (2020) Article DOI: 10.1021/acs.jmedchem.9b01689 BindingDB Entry DOI: 10.7270/Q2N3018J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase beta-2 (Mus musculus) | BDBM50511192![]() (CHEMBL4578086) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.69E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Weill Cornell Medicine Curated by ChEMBL | Assay Description Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi... | J Med Chem 63: 3004-3027 (2020) Article DOI: 10.1021/acs.jmedchem.9b01689 BindingDB Entry DOI: 10.7270/Q2N3018J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase beta-2 (Mus musculus) | BDBM50511184![]() (CHEMBL4518997) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Weill Cornell Medicine Curated by ChEMBL | Assay Description Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi... | J Med Chem 63: 3004-3027 (2020) Article DOI: 10.1021/acs.jmedchem.9b01689 BindingDB Entry DOI: 10.7270/Q2N3018J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase beta-2 (Mus musculus) | BDBM50511183![]() (CHEMBL4465979) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.17E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Weill Cornell Medicine Curated by ChEMBL | Assay Description Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi... | J Med Chem 63: 3004-3027 (2020) Article DOI: 10.1021/acs.jmedchem.9b01689 BindingDB Entry DOI: 10.7270/Q2N3018J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase beta-2 (Mus musculus) | BDBM50511185![]() (CHEMBL4446603) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.18E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Weill Cornell Medicine Curated by ChEMBL | Assay Description Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi... | J Med Chem 63: 3004-3027 (2020) Article DOI: 10.1021/acs.jmedchem.9b01689 BindingDB Entry DOI: 10.7270/Q2N3018J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase beta-2 (Mus musculus) | BDBM50511188![]() (CHEMBL4461928) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.75E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Weill Cornell Medicine Curated by ChEMBL | Assay Description Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi... | J Med Chem 63: 3004-3027 (2020) Article DOI: 10.1021/acs.jmedchem.9b01689 BindingDB Entry DOI: 10.7270/Q2N3018J | |||||||||||
More data for this Ligand-Target Pair |