| Reaction Details |
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 | Report a problem with these data |
| Target | Tryptase beta-2 |
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| Ligand | BDBM50511187 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1844054 (CHEMBL4344481) |
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| IC50 | 599±n/a nM |
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| Citation |  Giardina, SF; Werner, DS; Pingle, M; Feinberg, PB; Foreman, KW; Bergstrom, DE; Arnold, LD; Barany, F Novel, Self-Assembling Dimeric Inhibitors of Human ? Tryptase. J Med Chem63:3004-3027 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Tryptase beta-2 |
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| Name: | Tryptase beta-2 |
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| Synonyms: | 3.4.21.59 | Mast cell protease 6 | Mcpt6 | TRYB2_MOUSE | Tpsb2 | Tryptase beta-2 | Tryptase-2 | mMCP-6 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 30933.64 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_118951 |
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| Residue: | 276 |
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| Sequence: | MLKRRLLLLWALSLLASLVYSAPRPANQRVGIVGGHEASESKWPWQVSLRFKLNYWIHFC
GGSLIHPQWVLTAAHCVGPHIKSPQLFRVQLREQYLYYGDQLLSLNRIVVHPHYYTAEGG
ADVALLELEVPVNVSTHIHPISLPPASETFPPGTSCWVTGWGDIDNDEPLPPPYPLKQVK
VPIVENSLCDRKYHTGLYTGDDFPIVHDGMLCAGNTRRDSCQGDSGGPLVCKVKGTWLQA
GVVSWGEGCAQPNKPGIYTRVTYYLDWIHRYVPEHS
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| BDBM50511187 |
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| n/a |
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| Name | BDBM50511187 |
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| Synonyms: | CHEMBL4542067 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H26BClN2O4 |
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| Mol. Mass. | 476.76 |
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| SMILES | NCc1ccc2OCC3(CCN(CC3)C(=O)c3ccc(Cl)c(c3)-c3cccc(c3)B(O)O)c2c1 |
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| Structure | 
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