BindingDB PrimarySearch

Found 8 hits of ic50 for UniProtKB: Q9H2S1
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Small conductance calcium-activated potassium channel protein 2 (Homo sapiens (Human))	BDBM50263327 (CHEMBL476339 \| N-(4-methylpyridin-2-yl)-4-(pyridin...) Show SMILES Cc1ccnc(Nc2nc(cs2)-c2ccccn2)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Bristol Myers Squibb Co. Curated by ChEMBL					Assay Description Inhibition of Kca2.2 channel expressed in HEK293 cells by thallium flux assay				Bioorg Med Chem Lett 18: 5316-9 (2008) Article DOI: 10.1016/j.bmcl.2008.08.023 BindingDB Entry DOI: 10.7270/Q2N87BP1
Bristol Myers Squibb Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Homo sapiens (Human))	BDBM50263327 (CHEMBL476339 \| N-(4-methylpyridin-2-yl)-4-(pyridin...) Show SMILES Cc1ccnc(Nc2nc(cs2)-c2ccccn2)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Bristol Myers Squibb Co. Curated by ChEMBL					Assay Description Displacement of [125I]apamin from Kca2.2 channel expressed in HEK293 cells				Bioorg Med Chem Lett 18: 5316-9 (2008) Article DOI: 10.1016/j.bmcl.2008.08.023 BindingDB Entry DOI: 10.7270/Q2N87BP1
Bristol Myers Squibb Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Homo sapiens (Human))	BDBM50264020 (CHEMBL489770 \| GNF-PF-4773 \| N-(4-(pyridin-2-yl)th...) Show SMILES N(c1nc(cs1)-c1ccccn1)c1ccccn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	123	n/a	n/a	n/a	n/a	n/a	n/a
Bristol Myers Squibb Co. Curated by ChEMBL					Assay Description Inhibition of Kca2.2 channel expressed in HEK293 cells by thallium flux assay				Bioorg Med Chem Lett 18: 5316-9 (2008) Article DOI: 10.1016/j.bmcl.2008.08.023 BindingDB Entry DOI: 10.7270/Q2N87BP1
Bristol Myers Squibb Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Homo sapiens (Human))	BDBM50275960 (5-chloro-N-(thiophen-2-ylmethyl)pyrazolo[1,5-a]pyr...) Show SMILES Clc1cc(NCc2cccs2)n2nccc2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
Bristol Myers Squibb Co. Curated by ChEMBL					Assay Description Inhibition of Kca2.2 channel (unknown origin) expressed in HEK293 cells by thallium flux assay				Bioorg Med Chem Lett 18: 5694-7 (2008) Article DOI: 10.1016/j.bmcl.2008.08.026 BindingDB Entry DOI: 10.7270/Q2TM79Z6
Bristol Myers Squibb Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Homo sapiens (Human))	BDBM50264020 (CHEMBL489770 \| GNF-PF-4773 \| N-(4-(pyridin-2-yl)th...) Show SMILES N(c1nc(cs1)-c1ccccn1)c1ccccn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	543	n/a	n/a	n/a	n/a	n/a	n/a
Bristol Myers Squibb Co. Curated by ChEMBL					Assay Description Displacement of [125I]apamin from Kca2.2 channel expressed in HEK293 cells				Bioorg Med Chem Lett 18: 5316-9 (2008) Article DOI: 10.1016/j.bmcl.2008.08.023 BindingDB Entry DOI: 10.7270/Q2N87BP1
Bristol Myers Squibb Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Homo sapiens (Human))	BDBM50275792 (CHEMBL452406 \| N-benzyl-5-chloropyrazolo[1,5-a]pyr...) Show SMILES Clc1cc(NCc2ccccc2)n2nccc2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol Myers Squibb Co. Curated by ChEMBL					Assay Description Inhibition of Kca2.2 channel (unknown origin) expressed in HEK293 cells by thallium flux assay				Bioorg Med Chem Lett 18: 5694-7 (2008) Article DOI: 10.1016/j.bmcl.2008.08.026 BindingDB Entry DOI: 10.7270/Q2TM79Z6
Bristol Myers Squibb Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Homo sapiens (Human))	BDBM50377863 (AG-525 \| CHEMBL257156) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Inhibition of SK2 expressed in CHO FlipIn cells by whole cell patch-clamp assay				Bioorg Med Chem Lett 18: 3440-5 (2008) Article DOI: 10.1016/j.bmcl.2008.03.069 BindingDB Entry DOI: 10.7270/Q2N29XTJ
University of Li£ge Curated by ChEMBL					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Homo sapiens (Human))	BDBM50507839 (PF-6305591 \| Pf-06305591) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of SK2 (unknown origin)				Bioorg Med Chem 27: 230-239 (2019) Article DOI: 10.1016/j.bmc.2018.12.002 BindingDB Entry DOI: 10.7270/Q2ZK5KZN
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair