Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytoplasmic dynein 1 heavy chain 1 (Rattus norvegicus) | BDBM50184425 (CHEMBL206161 | Purealin) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Curated by ChEMBL | Assay Description Inhibition of MT-stimulated ATPase activity of rat cytoplasmic dynein heavy chain motor domain | J Med Chem 49: 2063-76 (2006) Article DOI: 10.1021/jm051030l BindingDB Entry DOI: 10.7270/Q2XS5W5T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytoplasmic dynein 1 heavy chain 1 (Rattus norvegicus) | BDBM50117089 (CHEMBL204484 | CHEMBL83995 | N-[2-(2-Amino-3H-imid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Curated by ChEMBL | Assay Description Inhibition of MT-stimulated ATPase activity of rat cytoplasmic dynein heavy chain motor domain | J Med Chem 49: 2063-76 (2006) Article DOI: 10.1021/jm051030l BindingDB Entry DOI: 10.7270/Q2XS5W5T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytoplasmic dynein 1 heavy chain 1 (Rattus norvegicus) | BDBM50184427 (CHEMBL206373 | Lipopurealin A) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Curated by ChEMBL | Assay Description Inhibition of MT-stimulated ATPase activity of rat cytoplasmic dynein heavy chain motor domain | J Med Chem 49: 2063-76 (2006) Article DOI: 10.1021/jm051030l BindingDB Entry DOI: 10.7270/Q2XS5W5T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytoplasmic dynein 1 heavy chain 1 (Rattus norvegicus) | BDBM50184424 (3-[2-(3-aminopropoxy)-3,5-dichlorophenyl]-2-hydrox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Curated by ChEMBL | Assay Description Inhibition of MT-stimulated ATPase activity of rat cytoplasmic dynein heavy chain motor domain | J Med Chem 49: 2063-76 (2006) Article DOI: 10.1021/jm051030l BindingDB Entry DOI: 10.7270/Q2XS5W5T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytoplasmic dynein 1 heavy chain 1 (Rattus norvegicus) | BDBM50184426 (3-[4-(3-aminopropoxy)-3-bromophenyl]-N-[2-(4-chlor...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Curated by ChEMBL | Assay Description Inhibition of MT-stimulated ATPase activity of rat cytoplasmic dynein heavy chain motor domain | J Med Chem 49: 2063-76 (2006) Article DOI: 10.1021/jm051030l BindingDB Entry DOI: 10.7270/Q2XS5W5T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytoplasmic dynein 1 heavy chain 1 (Rattus norvegicus) | BDBM50184421 (3-[4-(3-aminopropoxy)-3-bromophenyl]-2-hydroxyimin...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Curated by ChEMBL | Assay Description Inhibition of MT-stimulated ATPase activity of rat cytoplasmic dynein heavy chain motor domain | J Med Chem 49: 2063-76 (2006) Article DOI: 10.1021/jm051030l BindingDB Entry DOI: 10.7270/Q2XS5W5T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytoplasmic dynein 1 heavy chain 1 (Rattus norvegicus) | BDBM50184420 (3-[2-(3-aminopropoxy)-3,5-dibromophenyl]-2-hydroxy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Curated by ChEMBL | Assay Description Inhibition of MT-stimulated ATPase activity of rat cytoplasmic dynein heavy chain motor domain | J Med Chem 49: 2063-76 (2006) Article DOI: 10.1021/jm051030l BindingDB Entry DOI: 10.7270/Q2XS5W5T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytoplasmic dynein 1 heavy chain 1 (Rattus norvegicus) | BDBM50184423 (3-[2-(3-aminopropoxy)-3,5-dibromophenyl]-N-[2-(4-c...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Curated by ChEMBL | Assay Description Inhibition of MT-stimulated ATPase activity of rat cytoplasmic dynein heavy chain motor domain | J Med Chem 49: 2063-76 (2006) Article DOI: 10.1021/jm051030l BindingDB Entry DOI: 10.7270/Q2XS5W5T | |||||||||||
More data for this Ligand-Target Pair |