Found 375 hits of ic50 for UniProtKB: P54578 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590299
(US11560385, Compound 80B)Show SMILES Cc1cc(C(=O)CN2C3CC4CC(C3)CC2C4)c(C)n1-c1ccc(cc1)C#N |TLB:6:7:9:12.11.13,THB:11:12:7:9.10.16,11:10:7:12.14.13,6:7:12.14.13:9.10.16,14:12:9:7.15.16,14:15:9:12.11.13| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590309
(US11560385, Compound 90B)Show SMILES Cc1cc(C(=O)CN2C3CCC2[C@@H](O)C3)c(C)n1-c1ccc(C#N)c(F)c1 |r,TLB:6:7:12.14:10.9,THB:13:12:10.9:7| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590327
(US11560385, Compound 108B)Show SMILES Cc1c(cc(C2CCC2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2 |r,TLB:20:21:26.28:24.23,THB:27:26:24.23:21| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590680
(US11560385, Compound 120B)Show SMILES Cc1c(F)c(C(=O)CN2C3CCC2[C@@H](O)C3)c(C)n1-c1ccc(C#N)c(F)c1 |r,TLB:7:8:13.15:11.10,THB:14:13:11.10:8| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590687
(US11560385, Compound 128B)Show SMILES Cc1nc(Cc2c(Cl)c(C(=O)CN3C4CCC3[C@@H](O)C4)c(C)n2-c2ccc(cc2)C#N)cs1 |r,TLB:11:12:17.19:15.14,THB:18:17:15.14:12| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590691
(US11560385, Compound 132B)Show SMILES Cc1c(cc(C2CC(F)C2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2 |r,wD:27.31,TLB:21:22:27.29:25.24,THB:28:27:25.24:22,(-2.97,-.98,;-1.63,-.21,;-1.16,1.25,;.38,1.25,;.86,-.21,;2.35,-.61,;3.12,-1.95,;4.45,-1.18,;5.94,-1.58,;3.68,.16,;-.39,-1.12,;-.39,-2.66,;-1.72,-3.43,;-1.72,-4.97,;-.39,-5.74,;.95,-4.97,;.95,-3.43,;-.39,-7.28,;-.39,-8.82,;-2.24,2.34,;-3.73,1.94,;-1.85,3.83,;-2.93,4.92,;-4.03,6,;-2.7,6.77,;-2.3,8.26,;-3.63,7.49,;-5.17,7.49,;-5.94,8.82,;-5.57,6,)| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590692
(US11560385, Compound 133B)Show SMILES Cc1c(cc(CC2CCC2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2 |r,TLB:21:22:27.29:25.24,THB:28:27:25.24:22| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590693
(US11560385, Compound 134B)Show SMILES Cc1c(cc(CC2CC(C)(C)C2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2 |r,TLB:23:24:29.31:27.26,THB:30:29:27.26:24| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590694
(US11560385, Compound 135B)Show SMILES Cc1c(cc(CC2CC(F)(F)C2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2 |r,TLB:23:24:29.31:27.26,THB:30:29:27.26:24| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590695
(US11560385, Compound 136B)Show SMILES C[C@H]1CC2CCC1N2CC(=O)c1cc(C#N)n(c1C)-c1ccc(cc1)C#N |r,TLB:0:1:5.4:7,THB:8:7:1.2:5.4| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590696
(US11560385, Compound 137B)Show SMILES Cc1c(cc(C#N)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1CC2 |TLB:18:19:25.24:21.22| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590711
(US11560385, Compound 153B)Show SMILES Cc1c(cc(\C=C\CN2C(=O)c3ccccc3C2=O)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2 |r,TLB:30:31:36.38:34.33,THB:37:36:34.33:31| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590713
(US11560385, Compound 156B)Show SMILES Cc1c(cc(\C=C\CN)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2 |r,TLB:20:21:26.28:24.23,THB:27:26:24.23:21| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590191
(US11560385, Compound 1A)Show SMILES Cc1c(C(=O)CN2C3CCC2CC3)c2ccc(CCS(C)(=O)=O)cc2n1-c1ccc(Cl)cc1 |THB:5:6:12.11:8.9| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590192
(US11560385, Compound 2A)Show SMILES Cc1c(C(=O)CN2C3CCC2CCC3)c2ccc(CCS(C)(=O)=O)cc2n1-c1ccc(Cl)cc1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590194
(US11560385, Compound 4A)Show SMILES Cc1c(C(=O)CN2C3CCC2CC(O)C3)c2ccc(CCS(C)(=O)=O)cc2n1-c1ccc(Cl)cc1 |THB:13:12:8.9:6| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590195
(US11560385, Compound 5A)Show SMILES Cc1c(C(=O)CN2C3CCC2CC(O)C3)c2ccc(CCS(C)(=O)=O)cc2n1-c1ccc(Cl)cc1 |TLB:13:12:8.9:6| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590196
(US11560385, Compound 6A)Show SMILES Cc1c(C(=O)CN2C3CCC2[C@@H](O)C3)c2ccc(CCS(C)(=O)=O)cc2n1-c1ccc(Cl)cc1 |r,THB:5:6:11.13:9.8,12:11:9.8:6| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590197
(US11560385, Compound 7A)Show SMILES Cc1c(C(=O)CN2CCC(O)CC2)c2ccc(CCS(C)(=O)=O)cc2n1-c1ccc(Cl)cc1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590198
(US11560385, Compound 8A)Show SMILES Cc1c(C(=O)CN2C3CCC2CC3)c2ccc(CCC#N)cc2n1-c1ccc(Cl)cc1 |THB:5:6:12.11:8.9| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590200
(US11560385, Compound 10A | US11560385, Compound 15...)Show SMILES Cc1c(C(=O)CN2C3CCC2[C@@H](O)C3)c2ccc(CCC#N)cc2n1-c1ccc(Cl)cc1 |r,THB:5:6:11.13:9.8,12:11:9.8:6| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590201
(US11560385, Compound 11A)Show SMILES Cc1c(C(=O)CN2C3CCC2CC3)c2ccc(CC3COC3)cc2n1-c1ccc(Cl)cc1 |THB:5:6:12.11:8.9| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590203
(US11560385, Compound 13A)Show SMILES Cc1c(C(=O)CN2C3CCC2[C@@H](O)C3)c2ccc(CC3COC3)cc2n1-c1ccc(Cl)cc1 |r,THB:5:6:11.13:9.8,12:11:9.8:6| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590200
(US11560385, Compound 10A | US11560385, Compound 15...)Show SMILES Cc1c(C(=O)CN2C3CCC2[C@@H](O)C3)c2ccc(CCC#N)cc2n1-c1ccc(Cl)cc1 |r,THB:5:6:11.13:9.8,12:11:9.8:6| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590206
(US11560385, Compound 16A)Show SMILES Cc1c(C(=O)CN2C3CCC2CC3)c2ccc(CCS(=O)(=O)C3CC3)cc2n1-c1ccc(Cl)cc1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590207
(US11560385, Compound 17A)Show SMILES Cc1c(C(=O)CN2C3CCC2CC3)c2ccc(CCCC#N)cc2n1-c1ccc(Cl)cc1 |THB:5:6:12.11:8.9| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590208
(US11560385, Compound 18A)Show SMILES Cc1c(C(=O)CN2C3CCC2[C@@H](O)C3)c2ccc(CCCC#N)cc2n1-c1ccc(Cl)cc1 |r,THB:5:6:11.13:9.8,12:11:9.8:6| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590209
(US11560385, Compound 19A)Show SMILES Cc1c(C(=O)CN2C3CCC2[C@@H](CO)C3)c2ccc(CCCC#N)cc2n1-c1ccc(Cl)cc1 |r,THB:12:11:9.8:6,5:6:11.14:9.8| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590213
(US11560385, Compound 23A | US11560385, Compound 24...)Show SMILES Cc1c(C(=O)CN2C3CCC2CC(O)C3)c2ccc(CCS(=O)(=O)C3CC3)cc2n1-c1ccc(Cl)cc1 |THB:13:12:8.9:6| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590218
(US11560385, Compound 28A)Show SMILES CN1CCN=C1CCc1ccc2c(C(=O)CN3C4CCC3CC(O)C4)c(C)n(-c3ccc(Cl)cc3)c2c1 |c:4,THB:23:22:18.19:16| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590219
(US11560385, Compound 29A)Show SMILES CN1CCN=C1CCc1ccc2c(C(=O)CN3C4CCC3CC(O)C4)c(C)n(-c3ccc(Cl)cc3)c2c1 |c:4,TLB:23:22:18.19:16| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590223
(US11560385, Compound 33A)Show SMILES Cc1c(C(=O)CN2C3CCC2CCC3)c2ccc(CCC#N)cc2n1-c1ccc(Cl)cc1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590226
(US11560385, Compound 2B)Show SMILES Cc1c(cc(CCCC2CCOCC2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2 |r,TLB:25:26:31.33:29.28,THB:32:31:29.28:26| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590227
(US11560385, Compound 3B)Show SMILES Cc1c(cc(C#CCCC#N)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1CC2 |TLB:22:23:29.28:25.26| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590228
(US11560385, Compound 4B)Show SMILES Cc1c(cc(C[C@H]2C[C@H](C2)C#N)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2 |r,wU:6.5,8.10,wD:29.33,TLB:23:24:29.31:27.26,THB:30:29:27.26:24,(-3.57,-.98,;-2.24,-.21,;-1.76,1.25,;-.22,1.25,;.25,-.21,;1.74,-.61,;2.83,.48,;2.83,2.02,;4.37,2.02,;4.37,.48,;5.46,3.1,;6.55,4.19,;-.99,-1.12,;-.99,-2.66,;-2.33,-3.43,;-2.33,-4.97,;-.99,-5.74,;.34,-4.97,;.34,-3.43,;-.99,-7.28,;-.99,-8.82,;-2.85,2.34,;-4.34,1.94,;-2.45,3.83,;-3.54,4.92,;-4.64,6,;-3.3,6.77,;-2.9,8.26,;-4.24,7.49,;-5.78,7.49,;-6.55,8.82,;-6.18,6,)| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590230
(US11560385, Compound 6B)Show SMILES Cc1nccn1C\C=C\c1cc(C(=O)CN2C3CCC2[C@@H](O)C3)c(C)n1-c1ccc(cc1)C#N |r,TLB:14:15:20.22:18.17,THB:21:20:18.17:15| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590231
(US11560385, Compound 7B)Show SMILES Cc1c(cc(CCCCS(C)(=O)=O)n1-c1ccc(cc1)C#N)C(=O)CN1[C@@H]2CC[C@@H]1CC(O)C2 |r,TLB:24:25:27.28:30.33.31,THB:32:31:27.28:25| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590232
(US11560385, Compound 8B)Show SMILES Cc1c(cc(CCCCS(C)(=O)=O)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2 |r,TLB:24:25:30.32:28.27,THB:31:30:28.27:25| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590233
(US11560385, Compound 9B)Show SMILES Cc1c(cc(CCC2CCOCC2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2 |r,TLB:24:25:30.32:28.27,THB:31:30:28.27:25| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590234
(US11560385, Compound 10B)Show SMILES Cc1c(cc(C#CCCC#N)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2 |r,TLB:22:23:28.30:26.25,THB:29:28:26.25:23| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590236
(US11560385, Compound 12B)Show SMILES COCCCCc1cc(C(=O)CN2C3CCC2[C@@H](O)C3)c(C)n1-c1ccc(cc1)C#N |r,TLB:11:12:17.19:15.14,THB:18:17:15.14:12| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590237
(US11560385, Compound 13B)Show SMILES COCCCCc1cc(C(=O)CN2C3CCC2[C@H](O)C3)c(C)n1-c1ccc(cc1)C#N |r,THB:11:12:15.14:17.19,18:17:15.14:12| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590238
(US11560385, Compound 14B)Show SMILES Cc1c(cc(CCCCC2CCOCC2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2 |r,TLB:26:27:32.34:30.29,THB:33:32:30.29:27| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590239
(US11560385, Compound 15B)Show SMILES Cc1c(cc(\C=C\CC(C)(C)C#N)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2 |r,TLB:24:25:30.32:28.27,THB:31:30:28.27:25| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590244
(US11560385, Compound 20B)Show SMILES Cc1c(cc(\C=C\CCC#N)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2 |r,TLB:22:23:28.30:26.25,THB:29:28:26.25:23| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590246
(US11560385, Compound 22B)Show SMILES Cc1c(cc(CCCC2COC2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2 |r,TLB:23:24:29.31:27.26,THB:30:29:27.26:24| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590247
(US11560385, Compound 23B)Show SMILES Cc1c(cc(CCCCC2COC2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2 |r,TLB:24:25:30.32:28.27,THB:31:30:28.27:25| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590250
(US11560385, Compound 26B)Show SMILES Cc1c(cc(\C=C/CCS(C)(=O)=O)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1CC2 |TLB:24:25:31.30:27.28| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590251
(US11560385, Compound 27B)Show SMILES Cc1c(cc(\C=C\Cn2cccn2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2 |r,TLB:24:25:30.32:28.27,THB:31:30:28.27:25| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 14
(Homo sapiens (Human)) | BDBM590253
(US11560385, Compound 28B)Show SMILES Cc1c(cc(CCCCC#N)n1-c1ccc(cc1)C#N)C(=O)CN1C2CC3CC1CC(C2)O3 |TLB:22:23:25:30.32.31,22:23:30.29.31:25.26.27,THB:32:30:23:25.26.27,32:26:23:30.29.31,29:30:25:23.28.27,29:28:25:30.32.31| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2445RDM |
More data for this Ligand-Target Pair | |