BindingDB PrimarySearch

Found 707 hits Enz. Inhib. hit(s) with all data for entry = 3889
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50611509 (CHEMBL5284437) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50355244 (CHEMBL1835825) Show SMILES O=c1ccc2cc(ccc2o1)-c1ccc(cc1)C#N Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay				J Med Chem 54: 7055-65 (2011) Article DOI: 10.1021/jm2005404 BindingDB Entry DOI: 10.7270/Q27D2VJ6
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50198665 (CHEMBL3894599) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase expression after 24 hrs by alkaline...				Bioorg Med Chem 24: 5602-5610 (2016) Article DOI: 10.1016/j.bmc.2016.09.020 BindingDB Entry DOI: 10.7270/Q2R49SRM
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50198656 (CHEMBL3946113) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase expression after 24 hrs by alkaline...				Bioorg Med Chem 24: 5602-5610 (2016) Article DOI: 10.1016/j.bmc.2016.09.020 BindingDB Entry DOI: 10.7270/Q2R49SRM
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM444393 (N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	296	n/a	n/a	n/a	n/a	n/a	n/a
Toray Industries, Inc. US Patent					Assay Description Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...				US Patent US10662156 (2020) BindingDB Entry DOI: 10.7270/Q2W380B7
Toray Industries, Inc. US Patent					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM444330 (N-(amino(((5-(4-chlorophenyl)-6-(4-(trifluorometho...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	297	n/a	n/a	n/a	n/a	n/a	n/a
Toray Industries, Inc. US Patent					Assay Description Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...				US Patent US10662156 (2020) BindingDB Entry DOI: 10.7270/Q2W380B7
Toray Industries, Inc. US Patent					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50198673 (CHEMBL3975572) Show SMILES Cc1cc(=O)oc2cc(O)c(cc12)-c1ccc(C#N)n1C Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase expression after 24 hrs by alkaline...				Bioorg Med Chem 24: 5602-5610 (2016) Article DOI: 10.1016/j.bmc.2016.09.020 BindingDB Entry DOI: 10.7270/Q2R49SRM
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM444392 (N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Toray Industries, Inc. US Patent					Assay Description Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...				US Patent US10662156 (2020) BindingDB Entry DOI: 10.7270/Q2W380B7
Toray Industries, Inc. US Patent					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50203174 (CHEMBL3908173) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo Medical and Dental University Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells incubated for 24 hrs in presence of P4 by alkaline phosphatase assay				ACS Med Chem Lett 7: 1028-1033 (2016) Article DOI: 10.1021/acsmedchemlett.6b00184 BindingDB Entry DOI: 10.7270/Q22Z17HW
Tokyo Medical and Dental University Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50367097 (CHEMBL4173799) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at human CMX-AR expressed in HEK293 cells assessed as reduction in dihydrotestosterone-induced transactivation activity after 24 ...				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM444335 (N-(amino(((5-(3-chlorophenyl)-6-(4-chlorophenyl)py...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	308	n/a	n/a	n/a	n/a	n/a	n/a
Toray Industries, Inc. US Patent					Assay Description Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...				US Patent US10662156 (2020) BindingDB Entry DOI: 10.7270/Q2W380B7
Toray Industries, Inc. US Patent					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50355233 (CHEMBL1835826) Show SMILES CN(C)c1ccc(cc1)-c1ccc2oc(=O)ccc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay				J Med Chem 54: 7055-65 (2011) Article DOI: 10.1021/jm2005404 BindingDB Entry DOI: 10.7270/Q27D2VJ6
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50367118 (CHEMBL4160128) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50203180 (CHEMBL3945051) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo Medical and Dental University Curated by ChEMBL					Assay Description Displacement of [1,2,6,7-3H]-PG from recombinant human GST-tagged PR-LBD (657 to 933 residues) expressed in baculovirus infected insect cells measure...				ACS Med Chem Lett 7: 1028-1033 (2016) Article DOI: 10.1021/acsmedchemlett.6b00184 BindingDB Entry DOI: 10.7270/Q22Z17HW
Tokyo Medical and Dental University Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50062742 (CHEMBL3397786) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	311	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo Medical and Dental University Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-inducted alkaline phosphatase expression after 24 hrs by plate r...				Bioorg Med Chem 23: 803-9 (2015) Article DOI: 10.1016/j.bmc.2014.12.047 BindingDB Entry DOI: 10.7270/Q2XG9SS2
Tokyo Medical and Dental University Curated by ChEMBL					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM444355 (N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	314	n/a	n/a	n/a	n/a	n/a	n/a
Toray Industries, Inc. US Patent					Assay Description Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...				US Patent US10662156 (2020) BindingDB Entry DOI: 10.7270/Q2W380B7
Toray Industries, Inc. US Patent					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM444346 (N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	315	n/a	n/a	n/a	n/a	n/a	n/a
Toray Industries, Inc. US Patent					Assay Description Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...				US Patent US10662156 (2020) BindingDB Entry DOI: 10.7270/Q2W380B7
Toray Industries, Inc. US Patent					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM444367 (N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Toray Industries, Inc. US Patent					Assay Description Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...				US Patent US10662156 (2020) BindingDB Entry DOI: 10.7270/Q2W380B7
Toray Industries, Inc. US Patent					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50203154 (CHEMBL3953780) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo Medical and Dental University Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells incubated for 24 hrs in presence of P4 by alkaline phosphatase assay				ACS Med Chem Lett 7: 1028-1033 (2016) Article DOI: 10.1021/acsmedchemlett.6b00184 BindingDB Entry DOI: 10.7270/Q22Z17HW
Tokyo Medical and Dental University Curated by ChEMBL					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM444369 (N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	326	n/a	n/a	n/a	n/a	n/a	n/a
Toray Industries, Inc. US Patent					Assay Description Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...				US Patent US10662156 (2020) BindingDB Entry DOI: 10.7270/Q2W380B7
Toray Industries, Inc. US Patent					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50203195 (CHEMBL3942784) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo Medical and Dental University Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells incubated for 24 hrs in presence of P4 by alkaline phosphatase assay				ACS Med Chem Lett 7: 1028-1033 (2016) Article DOI: 10.1021/acsmedchemlett.6b00184 BindingDB Entry DOI: 10.7270/Q22Z17HW
Tokyo Medical and Dental University Curated by ChEMBL					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM444368 (N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	333	n/a	n/a	n/a	n/a	n/a	n/a
Toray Industries, Inc. US Patent					Assay Description Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...				US Patent US10662156 (2020) BindingDB Entry DOI: 10.7270/Q2W380B7
Toray Industries, Inc. US Patent					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM444332 (N-(amino(((5-(4-chlorophenyl)-6-(3-fluoro-4-methyl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	338	n/a	n/a	n/a	n/a	n/a	n/a
Toray Industries, Inc. US Patent					Assay Description Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...				US Patent US10662156 (2020) BindingDB Entry DOI: 10.7270/Q2W380B7
Toray Industries, Inc. US Patent					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50198659 (CHEMBL3946665) Show SMILES CC(=O)c1ccc(s1)-c1ccc2oc(=O)ccc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase expression after 24 hrs by alkaline...				Bioorg Med Chem 24: 5602-5610 (2016) Article DOI: 10.1016/j.bmc.2016.09.020 BindingDB Entry DOI: 10.7270/Q2R49SRM
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50367121 (CHEMBL4175249) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Displacement of [1,2,6,7-3H]progesterone from recombinant human GST-tagged PGR LBD (678 to 933 residues) expressed in baculovirus-infected insect cel...				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50396595 (CHEMBL2171906) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM444390 (N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	341	n/a	n/a	n/a	n/a	n/a	n/a
Toray Industries, Inc. US Patent					Assay Description Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...				US Patent US10662156 (2020) BindingDB Entry DOI: 10.7270/Q2W380B7
Toray Industries, Inc. US Patent					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM444331 (N-(amino(((5-(4-chlorophenyl)-6-(4-(trifluoromethy...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	348	n/a	n/a	n/a	n/a	n/a	n/a
Toray Industries, Inc. US Patent					Assay Description Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...				US Patent US10662156 (2020) BindingDB Entry DOI: 10.7270/Q2W380B7
Toray Industries, Inc. US Patent					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM444394 (N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	353	n/a	n/a	n/a	n/a	n/a	n/a
Toray Industries, Inc. US Patent					Assay Description Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...				US Patent US10662156 (2020) BindingDB Entry DOI: 10.7270/Q2W380B7
Toray Industries, Inc. US Patent					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM444348 (N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	356	n/a	n/a	n/a	n/a	n/a	n/a
Toray Industries, Inc. US Patent					Assay Description Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...				US Patent US10662156 (2020) BindingDB Entry DOI: 10.7270/Q2W380B7
Toray Industries, Inc. US Patent					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50355224 (CHEMBL1835817) Show SMILES CN(C)c1cc2oc(=O)ccc2cc1-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay				J Med Chem 54: 7055-65 (2011) Article DOI: 10.1021/jm2005404 BindingDB Entry DOI: 10.7270/Q27D2VJ6
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50367120 (CHEMBL4163940) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50611508 (CHEMBL5282720) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	368	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM444407 (N-(amino(((5,6-bis(4-chlorophenyl)-2-fluoropyridin...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	368	n/a	n/a	n/a	n/a	n/a	n/a
Toray Industries, Inc. US Patent					Assay Description Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...				US Patent US10662156 (2020) BindingDB Entry DOI: 10.7270/Q2W380B7
Toray Industries, Inc. US Patent					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50203178 (CHEMBL3930183) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo Medical and Dental University Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells incubated for 24 hrs in presence of P4 by alkaline phosphatase assay				ACS Med Chem Lett 7: 1028-1033 (2016) Article DOI: 10.1021/acsmedchemlett.6b00184 BindingDB Entry DOI: 10.7270/Q22Z17HW
Tokyo Medical and Dental University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member C3 (Homo sapiens (Human))	BDBM50543420 (CHEMBL4638008) Show SMILES Oc1cccc2oc(=N)c(cc12)C(=O)Nc1ccc(F)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Gifu Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant AKR1C3 (unknown origin) assessed as reduction in S-tetralol-induced dehydrogenase activity by measuring NADPH level				J Med Chem 63: 10396-10411 (2020) Article DOI: 10.1021/acs.jmedchem.0c00939 BindingDB Entry DOI: 10.7270/Q2V40ZSN
Gifu Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50543402 (CHEMBL4634960) Show SMILES Oc1cccc2cc(C(=O)Nc3cccc(F)c3)c(=N)oc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Gifu Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of CBR1 (unknown origin)				J Med Chem 63: 10396-10411 (2020) Article DOI: 10.1021/acs.jmedchem.0c00939 BindingDB Entry DOI: 10.7270/Q2V40ZSN
Gifu Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Mus musculus)	BDBM35909 (2-Hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-ph...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo Medical and Dental University Curated by ChEMBL					Assay Description Antagonist activity at androgen receptor in mouse SC3 cells assessed as inhibition of DHT-induced cell growth after 3 days by CCK-8/WST-8 assay				ACS Med Chem Lett 4: 937-41 (2013) Article DOI: 10.1021/ml4001744 BindingDB Entry DOI: 10.7270/Q2DF6SN4
Tokyo Medical and Dental University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM444403 (N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	373	n/a	n/a	n/a	n/a	n/a	n/a
Toray Industries, Inc. US Patent					Assay Description Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...				US Patent US10662156 (2020) BindingDB Entry DOI: 10.7270/Q2W380B7
Toray Industries, Inc. US Patent					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50355223 (CHEMBL1835816) Show SMILES CCN(CC)c1cc2oc(=O)ccc2cc1-c1cccc(c1)C#N Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay				J Med Chem 54: 7055-65 (2011) Article DOI: 10.1021/jm2005404 BindingDB Entry DOI: 10.7270/Q27D2VJ6
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50355220 (CHEMBL1835812) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay				J Med Chem 54: 7055-65 (2011) Article DOI: 10.1021/jm2005404 BindingDB Entry DOI: 10.7270/Q27D2VJ6
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM444372 (N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Toray Industries, Inc. US Patent					Assay Description Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...				US Patent US10662156 (2020) BindingDB Entry DOI: 10.7270/Q2W380B7
Toray Industries, Inc. US Patent					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50203184 (CHEMBL3980435) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo Medical and Dental University Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells incubated for 24 hrs in presence of P4 by alkaline phosphatase assay				ACS Med Chem Lett 7: 1028-1033 (2016) Article DOI: 10.1021/acsmedchemlett.6b00184 BindingDB Entry DOI: 10.7270/Q22Z17HW
Tokyo Medical and Dental University Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Mus musculus)	BDBM50450199 (CHEMBL4173412) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at AR in mouse SC3 cells assessed as inhibition of DHT-induced cell proliferation after 3 days by CCK8 assay				Bioorg Med Chem 26: 5118-5127 (2018) Article DOI: 10.1016/j.bmc.2018.09.008 BindingDB Entry DOI: 10.7270/Q2P271PJ
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50355221 (CHEMBL1835813) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assay				J Med Chem 54: 7055-65 (2011) Article DOI: 10.1021/jm2005404 BindingDB Entry DOI: 10.7270/Q27D2VJ6
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50611522 (CHEMBL5285346) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	401	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50062750 (CHEMBL3397785) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	404	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo Medical and Dental University Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-inducted alkaline phosphatase expression after 24 hrs by plate r...				Bioorg Med Chem 23: 803-9 (2015) Article DOI: 10.1016/j.bmc.2014.12.047 BindingDB Entry DOI: 10.7270/Q2XG9SS2
Tokyo Medical and Dental University Curated by ChEMBL					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM444381 (N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	408	n/a	n/a	n/a	n/a	n/a	n/a
Toray Industries, Inc. US Patent					Assay Description Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...				US Patent US10662156 (2020) BindingDB Entry DOI: 10.7270/Q2W380B7
Toray Industries, Inc. US Patent					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50203212 (CHEMBL3895538) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo Medical and Dental University Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells incubated for 24 hrs in presence of P4 by alkaline phosphatase assay				ACS Med Chem Lett 7: 1028-1033 (2016) Article DOI: 10.1021/acsmedchemlett.6b00184 BindingDB Entry DOI: 10.7270/Q22Z17HW
Tokyo Medical and Dental University Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50012248 (CHEMBL1765167) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair

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