Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate--cysteine ligase catalytic subunit (Homo sapiens (Human)) | BDBM50366432 (CHEMBL1627263) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | 390 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for inhibition of Escherichia coli gamma-glutamylcysteine synthetase at a concentration of 5.1 uM | Bioorg Med Chem Lett 6: 1437-1442 (1996) Article DOI: 10.1016/S0960-894X(96)00247-8 BindingDB Entry DOI: 10.7270/Q2KH0NV4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate--cysteine ligase catalytic subunit (Homo sapiens (Human)) | BDBM50287274 ((2S)-2-ammonio-4-[(2-carboxylatobutyl)phosphinato]...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article | 4.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for inhibition of Escherichia coli gamma-glutamylcysteine synthetase at a concentration of 5.7 uM | Bioorg Med Chem Lett 6: 1437-1442 (1996) Article DOI: 10.1016/S0960-894X(96)00247-8 BindingDB Entry DOI: 10.7270/Q2KH0NV4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate--cysteine ligase catalytic subunit (Homo sapiens (Human)) | BDBM50287275 (2-ammonio-4-[(2-carboxylatobutyl)sulfonyl]butanoat...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article | 9.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for inhibition of Escherichia coli gamma-glutamylcysteine synthetase at a concentration of 16.3 uM | Bioorg Med Chem Lett 6: 1437-1442 (1996) Article DOI: 10.1016/S0960-894X(96)00247-8 BindingDB Entry DOI: 10.7270/Q2KH0NV4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate--cysteine ligase catalytic subunit (Homo sapiens (Human)) | BDBM50366433 (CHEMBL1609891) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | 4.93E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for inhibition of Escherichia coli gamma-glutamylcysteine synthetase at a concentration of 25.0 uM | Bioorg Med Chem Lett 6: 1437-1442 (1996) Article DOI: 10.1016/S0960-894X(96)00247-8 BindingDB Entry DOI: 10.7270/Q2KH0NV4 | |||||||||||
More data for this Ligand-Target Pair |