Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1-deoxy-D-xylulose-5-phosphate synthase (Escherichia coli K-12 (Enterobacteria)) | BDBM50496737 (CHEMBL3220783) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 960 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Johns Hopkins University School of Medicine Curated by ChEMBL | Assay Description Competitive inhibition of ThDP-dependent Escherichia coli DXP synthase using pyruvate as substrate assessed as NADPH consumption by spectrophotometri... | Medchemcomm 3: 65-67 (2012) Article DOI: 10.1039/c1md00233c BindingDB Entry DOI: 10.7270/Q2P55RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Escherichia coli K-12 (Enterobacteria)) | BDBM50496738 (CHEMBL3220785) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Johns Hopkins University School of Medicine Curated by ChEMBL | Assay Description Competitive inhibition of ThDP-dependent Escherichia coli DXP synthase using pyruvate as substrate assessed as NADPH consumption by spectrophotometri... | Medchemcomm 3: 65-67 (2012) Article DOI: 10.1039/c1md00233c BindingDB Entry DOI: 10.7270/Q2P55RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Escherichia coli K-12 (Enterobacteria)) | BDBM50496736 (CHEMBL3220784) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 6.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Johns Hopkins University School of Medicine Curated by ChEMBL | Assay Description Competitive inhibition of ThDP-dependent Escherichia coli DXP synthase using pyruvate as substrate assessed as NADPH consumption by spectrophotometri... | Medchemcomm 3: 65-67 (2012) Article DOI: 10.1039/c1md00233c BindingDB Entry DOI: 10.7270/Q2P55RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Escherichia coli K-12 (Enterobacteria)) | BDBM50496741 (CHEMBL3220786) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.58E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Johns Hopkins University School of Medicine Curated by ChEMBL | Assay Description Competitive inhibition of ThDP-dependent Escherichia coli DXP synthase using pyruvate as substrate assessed as NADPH consumption by spectrophotometri... | Medchemcomm 3: 65-67 (2012) Article DOI: 10.1039/c1md00233c BindingDB Entry DOI: 10.7270/Q2P55RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Escherichia coli K-12 (Enterobacteria)) | BDBM108228 (1‐nitroso‐2‐naphthol (Substrate ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 4.22E+5 | -4.79 | 1.07E+6 | n/a | n/a | n/a | n/a | 8.0 | 37 |
The Johns Hopkins University School of Medicine, 725 North Wolfe St, Baltimore, MD 21205, USA | Assay Description Reaction mixtures containing HEPES (100mM, pH 8.0, 2mM MgCl2, 5mM NaCl), ThDP (1mM), BSA (1mg/mL), DMSO (10%, v/v), ᴅ-GAP (30µM), pyruvate... | Chembiochem 14: 1309-15 (2013) Article DOI: 10.1002/cbic.201300187 BindingDB Entry DOI: 10.7270/Q2J101T3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Escherichia coli K-12 (Enterobacteria)) | BDBM50496739 (CHEMBL3220787) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Johns Hopkins University School of Medicine Curated by ChEMBL | Assay Description Competitive inhibition of ThDP-dependent Escherichia coli DXP synthase using pyruvate as substrate assessed as NADPH consumption by spectrophotometri... | Medchemcomm 3: 65-67 (2012) Article DOI: 10.1039/c1md00233c BindingDB Entry DOI: 10.7270/Q2P55RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Escherichia coli K-12 (Enterobacteria)) | BDBM50496740 (CHEMBL3220788) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Johns Hopkins University School of Medicine Curated by ChEMBL | Assay Description Competitive inhibition of ThDP-dependent Escherichia coli DXP synthase using pyruvate as substrate assessed as NADPH consumption by spectrophotometri... | Medchemcomm 3: 65-67 (2012) Article DOI: 10.1039/c1md00233c BindingDB Entry DOI: 10.7270/Q2P55RGT | |||||||||||
More data for this Ligand-Target Pair |