Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2C (Mus musculus (Mouse)) | BDBM50060417 (5-Methyl-3,5-dihydro-2H-pyrrolo[2,3-f]indole-1-car...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Binding affinity analysed on 5-HT 2C in human clone using [3H]mesulergine as radioligand | J Med Chem 39: 2773-80 (1996) Article DOI: 10.1021/jm960062t BindingDB Entry DOI: 10.7270/Q2DZ09G0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Mus musculus (Mouse)) | BDBM50017721 (1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)pipe...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Binding affininity of the compound to 5-hydroxytryptamine 2C receptor using [3H]-Mesulergine as radioligand in stably transfected NIH3T3 cells | Bioorg Med Chem Lett 11: 655-8 (2001) BindingDB Entry DOI: 10.7270/Q2H994F8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Mus musculus (Mouse)) | BDBM35920 (9,10-dihydroanthracene(DHA), 1a | 9-(Aminomethyl)-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Binding affinity to 5-hydroxytryptamine 2C receptor using [3H]Mesulergine as radioligand in stably transfected NIH3T3 cells | Bioorg Med Chem Lett 11: 655-8 (2001) BindingDB Entry DOI: 10.7270/Q2H994F8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Mus musculus (Mouse)) | BDBM82272 (SB 200646 | SB200646a) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 138 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Binding affinity analysed on 5-HT 2C in rat stomach fundus | J Med Chem 39: 2773-80 (1996) Article DOI: 10.1021/jm960062t BindingDB Entry DOI: 10.7270/Q2DZ09G0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Mus musculus (Mouse)) | BDBM50010859 (CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | 160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Binding affininity of the compound to 5-hydroxytryptamine 2C receptor using [3H]-Mesulergine as radioligand in stably transfected NIH3T3 cells | Bioorg Med Chem Lett 11: 655-8 (2001) BindingDB Entry DOI: 10.7270/Q2H994F8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Mus musculus (Mouse)) | BDBM186969 (US9079895, 32s) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
University of Dundee US Patent | Assay Description The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un... | US Patent US9079895 (2015) BindingDB Entry DOI: 10.7270/Q2D7996K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Mus musculus (Mouse)) | BDBM84991 (CAS_3277600 | NSC_3277600 | SB204741) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents | Article PubMed | 1.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Binding affinity analysed on 5-HT 2C in human clone using [3H]mesulergine as radioligand | J Med Chem 39: 2773-80 (1996) Article DOI: 10.1021/jm960062t BindingDB Entry DOI: 10.7270/Q2DZ09G0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Mus musculus (Mouse)) | BDBM186935 (US9079895, 23s) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 3.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
University of Dundee US Patent | Assay Description The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un... | US Patent US9079895 (2015) BindingDB Entry DOI: 10.7270/Q2D7996K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Mus musculus (Mouse)) | BDBM186937 (US9079895, 25s) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 3.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
University of Dundee US Patent | Assay Description The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un... | US Patent US9079895 (2015) BindingDB Entry DOI: 10.7270/Q2D7996K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Mus musculus (Mouse)) | BDBM186968 (US9079895, 70) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 6.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
University of Dundee US Patent | Assay Description The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un... | US Patent US9079895 (2015) BindingDB Entry DOI: 10.7270/Q2D7996K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Mus musculus (Mouse)) | BDBM186927 (US9079895, 19s) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 6.74E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
University of Dundee US Patent | Assay Description The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un... | US Patent US9079895 (2015) BindingDB Entry DOI: 10.7270/Q2D7996K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Mus musculus (Mouse)) | BDBM85098 (N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health Curated by PDSP Ki Database | J Pharmacol Exp Ther 308: 481-6 (2004) Article DOI: 10.1124/jpet.103.058636 BindingDB Entry DOI: 10.7270/Q2QZ28J1 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Mus musculus (Mouse)) | BDBM50013515 ((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Binding affinity analysed towards 5-HT 2C in rat stomach fundus | J Med Chem 39: 2773-80 (1996) Article DOI: 10.1021/jm960062t BindingDB Entry DOI: 10.7270/Q2DZ09G0 | |||||||||||
More data for this Ligand-Target Pair |