Compile Data Set for Download or QSAR

Found 10 hits of kd for UniProtKB: P18031   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 1 [1-298] (Homo sapiens (Human))	BDBM13958 (2-[(7-Hydroxynaphthalen-1-yl)oxalylamino]benzoic A...) Show SMILES OC(=O)C(=O)N(c1ccccc1C(O)=O)c1cccc2ccc(O)cc12 Show InChI InChI=1S/C19H13NO6/c21-12-9-8-11-4-3-7-16(14(11)10-12)20(17(22)19(25)26)15-6-2-1-5-13(15)18(23)24/h1-10,21H,(H,23,24)(H,25,26)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	DrugBank MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB Article PubMed	1.70E+4	-6.44	n/a	8.00E+3	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...				J Med Chem 46: 2093-103 (2003) Article DOI: 10.1021/jm0205696 BindingDB Entry DOI: 10.7270/Q26H4FPH
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tyrosine-protein phosphatase non-receptor type 1 [1-298] (Homo sapiens (Human))	BDBM13957 (2-(Naphthalen-2-yloxalylamino)benzoic Acid | 2-(na...) Show SMILES OC(=O)C(=O)N(c1ccc2ccccc2c1)c1ccccc1C(O)=O Show InChI InChI=1S/C19H13NO5/c21-17(19(24)25)20(16-8-4-3-7-15(16)18(22)23)14-10-9-12-5-1-2-6-13(12)11-14/h1-11H,(H,22,23)(H,24,25)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.90E+4	-5.95	n/a	1.10E+4	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...				J Med Chem 46: 2093-103 (2003) Article DOI: 10.1021/jm0205696 BindingDB Entry DOI: 10.7270/Q26H4FPH
					More data for this Ligand-Target Pair				3D Structure (docked)
Tyrosine-protein phosphatase non-receptor type 1 [1-298] (Homo sapiens (Human))	BDBM13965 (2-[Oxalyl(2-piperidin-1-ylphenyl)amino]benzoic Aci...) Show SMILES OC(=O)C(=O)N(c1ccccc1N1CCCCC1)c1ccccc1C(O)=O Show InChI InChI=1S/C20H20N2O5/c23-18(20(26)27)22(15-9-3-2-8-14(15)19(24)25)17-11-5-4-10-16(17)21-12-6-1-7-13-21/h2-5,8-11H,1,6-7,12-13H2,(H,24,25)(H,26,27)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.40E+4	-6.55	n/a	1.30E+4	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...				J Med Chem 46: 2093-103 (2003) Article DOI: 10.1021/jm0205696 BindingDB Entry DOI: 10.7270/Q26H4FPH
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 [1-298] (Homo sapiens (Human))	BDBM13952 (2-(Naphthalen-1-yloxalylamino)benzoic Acid | 2-(na...) Show SMILES OC(=O)C(=O)N(c1ccccc1C(O)=O)c1cccc2ccccc12 Show InChI InChI=1S/C19H13NO5/c21-17(19(24)25)20(16-10-4-3-9-14(16)18(22)23)15-11-5-7-12-6-1-2-8-13(12)15/h1-11H,(H,22,23)(H,24,25)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB Article PubMed	2.40E+4	-6.23	n/a	2.60E+4	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...				J Med Chem 46: 2093-103 (2003) Article DOI: 10.1021/jm0205696 BindingDB Entry DOI: 10.7270/Q26H4FPH
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tyrosine-protein phosphatase non-receptor type 1 [1-298] (Homo sapiens (Human))	BDBM13963 (2-{[2-(2-Hydroxyethyl)phenyl]oxalylamino}benzoic A...) Show SMILES OCCc1ccccc1N(C(=O)C(O)=O)c1ccccc1C(O)=O Show InChI InChI=1S/C17H15NO6/c19-10-9-11-5-1-3-7-13(11)18(15(20)17(23)24)14-8-4-2-6-12(14)16(21)22/h1-8,19H,9-10H2,(H,21,22)(H,23,24)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.70E+4	-6.44	n/a	3.50E+4	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...				J Med Chem 46: 2093-103 (2003) Article DOI: 10.1021/jm0205696 BindingDB Entry DOI: 10.7270/Q26H4FPH
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 [1-298] (Homo sapiens (Human))	BDBM13962 (2-[(2-Benzylphenyl)oxalylamino]benzoic Acid | 2-[(...) Show SMILES OC(=O)C(=O)N(c1ccccc1Cc1ccccc1)c1ccccc1C(O)=O Show InChI InChI=1S/C22H17NO5/c24-20(22(27)28)23(19-13-7-5-11-17(19)21(25)26)18-12-6-4-10-16(18)14-15-8-2-1-3-9-15/h1-13H,14H2,(H,25,26)(H,27,28)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.40E+4	-6.23	n/a	3.50E+4	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...				J Med Chem 46: 2093-103 (2003) Article DOI: 10.1021/jm0205696 BindingDB Entry DOI: 10.7270/Q26H4FPH
					More data for this Ligand-Target Pair				3D Structure (docked)
Tyrosine-protein phosphatase non-receptor type 1 [1-298] (Homo sapiens (Human))	BDBM13961 (2-[(2-Isopropylphenyl)oxalylamino]benzoic Acid | 2...) Show SMILES CC(C)c1ccccc1N(C(=O)C(O)=O)c1ccccc1C(O)=O Show InChI InChI=1S/C18H17NO5/c1-11(2)12-7-3-5-9-14(12)19(16(20)18(23)24)15-10-6-4-8-13(15)17(21)22/h3-11H,1-2H3,(H,21,22)(H,23,24)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.50E+4	-6.01	n/a	4.90E+4	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...				J Med Chem 46: 2093-103 (2003) Article DOI: 10.1021/jm0205696 BindingDB Entry DOI: 10.7270/Q26H4FPH
					More data for this Ligand-Target Pair				3D Structure (docked)
Tyrosine-protein phosphatase non-receptor type 1 [1-298] (Homo sapiens (Human))	BDBM13960 (2-[(2-Ethylphenyl)oxalylamino]benzoic Acid | 2-[(2...) Show SMILES CCc1ccccc1N(C(=O)C(O)=O)c1ccccc1C(O)=O Show InChI InChI=1S/C17H15NO5/c1-2-11-7-3-5-9-13(11)18(15(19)17(22)23)14-10-6-4-8-12(14)16(20)21/h3-10H,2H2,1H3,(H,20,21)(H,22,23)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	6.00E+4	-5.70	n/a	5.00E+4	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...				J Med Chem 46: 2093-103 (2003) Article DOI: 10.1021/jm0205696 BindingDB Entry DOI: 10.7270/Q26H4FPH
					More data for this Ligand-Target Pair				3D Structure (docked)
Tyrosine-protein phosphatase non-receptor type 1 [1-298] (Homo sapiens (Human))	BDBM13959 (2-(5,6,7,8-tetrahydronaphthalen-1-ylamidoformic ac...) Show SMILES OC(=O)C(=O)N(c1cccc2CCCCc12)c1ccccc1C(O)=O Show InChI InChI=1S/C19H17NO5/c21-17(19(24)25)20(16-10-4-3-9-14(16)18(22)23)15-11-5-7-12-6-1-2-8-13(12)15/h3-5,7,9-11H,1-2,6,8H2,(H,22,23)(H,24,25)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.40E+4	-5.57	n/a	7.10E+4	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...				J Med Chem 46: 2093-103 (2003) Article DOI: 10.1021/jm0205696 BindingDB Entry DOI: 10.7270/Q26H4FPH
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 [1-298] (Homo sapiens (Human))	BDBM13951 (2-[(2,3-Dimethylphenyl)oxalylamino]benzoic acid | ...) Show SMILES Cc1cccc(N(C(=O)C(O)=O)c2ccccc2C(O)=O)c1C Show InChI InChI=1S/C17H15NO5/c1-10-6-5-9-13(11(10)2)18(15(19)17(22)23)14-8-4-3-7-12(14)16(20)21/h3-9H,1-2H3,(H,20,21)(H,22,23)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.30E+4	-5.44	n/a	1.24E+5	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...				J Med Chem 46: 2093-103 (2003) Article DOI: 10.1021/jm0205696 BindingDB Entry DOI: 10.7270/Q26H4FPH
					More data for this Ligand-Target Pair				3D Structure (docked)