Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Pantothenate synthetase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50400285![]() (CHEMBL1229883) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL MMDB PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 860 | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana Curated by ChEMBL | Assay Description Binding affinity to Mycobacterium tuberculosis Pantothenate synthetase | J Med Chem 54: 915-29 (2011) Article DOI: 10.1021/jm101121s BindingDB Entry DOI: 10.7270/Q2NS0W23 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Pantothenate synthetase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50400287![]() (CHEMBL1232724) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana Curated by ChEMBL | Assay Description Binding affinity to Mycobacterium tuberculosis Pantothenate synthetase | J Med Chem 54: 915-29 (2011) Article DOI: 10.1021/jm101121s BindingDB Entry DOI: 10.7270/Q2NS0W23 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Pantothenate synthetase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50400286![]() (CHEMBL1232727) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL MMDB PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana Curated by ChEMBL | Assay Description Binding affinity to Mycobacterium tuberculosis Pantothenate synthetase | J Med Chem 54: 915-29 (2011) Article DOI: 10.1021/jm101121s BindingDB Entry DOI: 10.7270/Q2NS0W23 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Pantothenate synthetase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50441674![]() (CHEMBL2435654) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology and Science - Pilani Curated by ChEMBL | Assay Description Binding affinity to Mycobacterium tuberculosis pantothenate synthetase | Eur J Med Chem 69: 356-64 (2013) Article DOI: 10.1016/j.ejmech.2013.08.036 BindingDB Entry DOI: 10.7270/Q2H996NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pantothenate synthetase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50400277![]() (CHEMBL1232723) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 2.90E+4 | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana Curated by ChEMBL | Assay Description Binding affinity to Mycobacterium tuberculosis Pantothenate synthetase | J Med Chem 54: 915-29 (2011) Article DOI: 10.1021/jm101121s BindingDB Entry DOI: 10.7270/Q2NS0W23 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Pantothenate synthetase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM84864![]() (5'-Deoxy-5'-thiodenosine scaffold, 14b) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 8.00E+4 | n/a | n/a | n/a | 7.6 | 25 |
University of Cambridge | Assay Description The dissociation constants and enthalpies was determined by isothermal titration calorimety. | Chembiochem 10: 2772-9 (2009) Checked by Author Article DOI: 10.1002/cbic.200900537 BindingDB Entry DOI: 10.7270/Q21J988R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pantothenate synthetase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50400278![]() (CHEMBL1230737) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 8.00E+4 | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana Curated by ChEMBL | Assay Description Binding affinity to Mycobacterium tuberculosis Pantothenate synthetase | J Med Chem 54: 915-29 (2011) Article DOI: 10.1021/jm101121s BindingDB Entry DOI: 10.7270/Q2NS0W23 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Pantothenate synthetase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM84863![]() (5'-Deoxy-5'-thiodenosine scaffold, 14a) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | KEGG MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 2.10E+5 | n/a | n/a | n/a | 7.6 | 25 |
University of Cambridge | Assay Description The dissociation constants and enthalpies was determined by isothermal titration calorimety. | Chembiochem 10: 2772-9 (2009) Checked by Author Article DOI: 10.1002/cbic.200900537 BindingDB Entry DOI: 10.7270/Q21J988R | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Pantothenate synthetase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM84863![]() (5'-Deoxy-5'-thiodenosine scaffold, 14a) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | KEGG MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 2.10E+5 | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana Curated by ChEMBL | Assay Description Binding affinity to Mycobacterium tuberculosis Pantothenate synthetase | J Med Chem 54: 915-29 (2011) Article DOI: 10.1021/jm101121s BindingDB Entry DOI: 10.7270/Q2NS0W23 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Pantothenate synthetase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM84862![]() (5'-Deoxy-5'-thiodenosine scaffold, 6) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | 3.80E+5 | n/a | n/a | n/a | 7.6 | 25 |
University of Cambridge | Assay Description The dissociation constants and enthalpies was determined by isothermal titration calorimety. | Chembiochem 10: 2772-9 (2009) Checked by Author Article DOI: 10.1002/cbic.200900537 BindingDB Entry DOI: 10.7270/Q21J988R | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Pantothenate synthetase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM84862![]() (5'-Deoxy-5'-thiodenosine scaffold, 6) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | 3.80E+5 | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana Curated by ChEMBL | Assay Description Competitive inhibition of Mycobacterium tuberculosis Pantothenate synthetase by ITC method | J Med Chem 54: 915-29 (2011) Article DOI: 10.1021/jm101121s BindingDB Entry DOI: 10.7270/Q2NS0W23 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Pantothenate synthetase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM84866![]() (5'-Deoxy-5'-thiodenosine scaffold, 18) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 5.40E+5 | n/a | n/a | n/a | 7.6 | 25 |
University of Cambridge | Assay Description The dissociation constants and enthalpies was determined by isothermal titration calorimety. | Chembiochem 10: 2772-9 (2009) Checked by Author Article DOI: 10.1002/cbic.200900537 BindingDB Entry DOI: 10.7270/Q21J988R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pantothenate synthetase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM84865![]() (5'-Deoxy-5'-thiodenosine scaffold, 14c) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 5.70E+5 | n/a | n/a | n/a | 7.6 | 25 |
University of Cambridge | Assay Description The dissociation constants and enthalpies was determined by isothermal titration calorimety. | Chembiochem 10: 2772-9 (2009) Checked by Author Article DOI: 10.1002/cbic.200900537 BindingDB Entry DOI: 10.7270/Q21J988R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pantothenate synthetase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50400284![]() (CHEMBL2181056) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 8.00E+5 | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana Curated by ChEMBL | Assay Description Binding affinity to Mycobacterium tuberculosis Pantothenate synthetase | J Med Chem 54: 915-29 (2011) Article DOI: 10.1021/jm101121s BindingDB Entry DOI: 10.7270/Q2NS0W23 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pantothenate synthetase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50345230![]() (1-benzofuran-2-carboxylic acid | CHEMBL84095 | ben...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | 1.00E+6 | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana Curated by ChEMBL | Assay Description Binding affinity to Mycobacterium tuberculosis Pantothenate synthetase | J Med Chem 54: 915-29 (2011) Article DOI: 10.1021/jm101121s BindingDB Entry DOI: 10.7270/Q2NS0W23 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Pantothenate synthetase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50400288![]() (CHEMBL280311) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 1.10E+6 | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana Curated by ChEMBL | Assay Description Binding affinity to Mycobacterium tuberculosis Pantothenate synthetase ATP-binding site by ITC method | J Med Chem 54: 915-29 (2011) Article DOI: 10.1021/jm101121s BindingDB Entry DOI: 10.7270/Q2NS0W23 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |