| Reaction Details |
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 | Report a problem with these data |
| Target | Pantothenate synthetase |
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| Ligand | BDBM50441674 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_988133 (CHEMBL2439102) |
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| Kd | 1800±n/a nM |
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| Citation |  Samala, G; Devi, PB; Nallangi, R; Yogeeswari, P; Sriram, D Development of 3-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine derivatives as novel Mycobacterium tuberculosis pantothenate synthetase inhibitors. Eur J Med Chem69:356-64 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Pantothenate synthetase |
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| Name: | Pantothenate synthetase |
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| Synonyms: | Chain A, Crystal Structure Of A Pantothenate Synthetase, Apo Enzyme In C2 Space Group | PANC_MYCTU | Pantothenate synthetase | panC |
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| Type: | n/a |
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| Mol. Mass.: | 32675.10 |
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| Organism: | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
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| Description: | ChEMBL_102878 |
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| Residue: | 309 |
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| Sequence: | MTIPAFHPGELNVYSAPGDVADVSRALRLTGRRVMLVPTMGALHEGHLALVRAAKRVPGS
VVVVSIFVNPMQFGAGEDLDAYPRTPDDDLAQLRAEGVEIAFTPTTAAMYPDGLRTTVQP
GPLAAELEGGPRPTHFAGVLTVVLKLLQIVRPDRVFFGEKDYQQLVLIRQLVADFNLDVA
VVGVPTVREADGLAMSSRNRYLDPAQRAAAVALSAALTAAAHAATAGAQAALDAARAVLD
AAPGVAVDYLELRDIGLGPMPLNGSGRLLVAARLGTTRLLDNIAIEIGTFAGTDRPDGYR
AILESHWRN
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| BDBM50441674 |
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| n/a |
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| Name | BDBM50441674 |
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| Synonyms: | CHEMBL2435654 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H17NO6S |
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| Mol. Mass. | 411.428 |
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| SMILES | Cc1ccc2C(CC(O)=O)C(=Cc2c1)C(=O)NS(=O)(=O)c1cc2ccccc2o1 |c:10| |
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| Structure | 
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