Compile Data Set for Download or QSAR

Found 124 hits of kd for UniProtKB: P02766   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transthyretin (Homo sapiens (Human))	BDBM50225226 (4-(2,4-dichlorophenoxy)-3-methoxybenzoic acid | CH...) Show SMILES COc1cc(ccc1Oc1ccc(Cl)cc1Cl)C(O)=O Show InChI InChI=1S/C14H10Cl2O4/c1-19-13-6-8(14(17)18)2-4-12(13)20-11-5-3-9(15)7-10(11)16/h2-7H,1H3,(H,17,18)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	0.200	n/a	n/a	n/a	4.4	n/a
Institute of Sciences Curated by ChEMBL					Assay Description Binding affinity to transthyretin at pH 4.4				J Med Chem 50: 5589-99 (2007) Article DOI: 10.1021/jm0700159 BindingDB Entry DOI: 10.7270/Q2PG1RGD
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50225216 (2-(2,4-dichlorophenoxy)-5-(hydroxymethyl)phenol | ...) Show SMILES OCc1ccc(Oc2ccc(Cl)cc2Cl)c(O)c1 Show InChI InChI=1S/C13H10Cl2O3/c14-9-2-4-12(10(15)6-9)18-13-3-1-8(7-16)5-11(13)17/h1-6,16-17H,7H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	0.300	n/a	n/a	n/a	4.4	n/a
Institute of Sciences Curated by ChEMBL					Assay Description Binding affinity to transthyretin at pH 4.4				J Med Chem 50: 5589-99 (2007) Article DOI: 10.1021/jm0700159 BindingDB Entry DOI: 10.7270/Q2PG1RGD
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | US10377729, Co...) Show SMILES OC(=O)c1ccc2nc(oc2c1)-c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C14H7Cl2NO3/c15-9-3-8(4-10(16)6-9)13-17-11-2-1-7(14(18)19)5-12(11)20-13/h1-6H,(H,18,19)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to wild type TTR (unknown origin) assessed as Kd1 by isothermal titration calorimetry				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00934 BindingDB Entry DOI: 10.7270/Q2CN77M6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transthyretin (Homo sapiens (Human))	BDBM50197882 (CHEMBL3959466) Show SMILES Cc1c(\C=C\c2ccc(Cl)o2)occ1C(O)=O Show InChI InChI=1S/C12H9ClO4/c1-7-9(12(14)15)6-16-10(7)4-2-8-3-5-11(13)17-8/h2-6H,1H3,(H,14,15)/b4-2+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a
Universidade de Coimbra Curated by ChEMBL					Assay Description Binding affinity to recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as dissociation constants for first binding sit...				Eur J Med Chem 121: 823-840 (2016) Article DOI: 10.1016/j.ejmech.2016.02.074 BindingDB Entry DOI: 10.7270/Q26975JG
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50197881 (CHEMBL3890392) Show SMILES Cc1oc(\C=C\c2ccc(Cl)o2)cc1C(O)=O Show InChI InChI=1S/C12H9ClO4/c1-7-10(12(14)15)6-9(16-7)3-2-8-4-5-11(13)17-8/h2-6H,1H3,(H,14,15)/b3-2+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a
Universidade de Coimbra Curated by ChEMBL					Assay Description Binding affinity to recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as dissociation constants for first binding sit...				Eur J Med Chem 121: 823-840 (2016) Article DOI: 10.1016/j.ejmech.2016.02.074 BindingDB Entry DOI: 10.7270/Q26975JG
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | US10377729, Co...) Show SMILES OC(=O)c1ccc2nc(oc2c1)-c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C14H7Cl2NO3/c15-9-3-8(4-10(16)6-9)13-17-11-2-1-7(14(18)19)5-12(11)20-13/h1-6H,(H,18,19)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a
University of the Pacific Curated by ChEMBL					Assay Description Binding affinity to transthyretin (unknown origin) by ITC method				J Med Chem 61: 7862-7876 (2018) Article DOI: 10.1021/acs.jmedchem.8b00817 BindingDB Entry DOI: 10.7270/Q2KP84SS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transthyretin (Homo sapiens (Human))	BDBM50197885 (CHEMBL3940890) Show SMILES Cc1n[nH]c(C)c1CCCOc1cc(ccc1F)C(O)=O Show InChI InChI=1S/C15H17FN2O3/c1-9-12(10(2)18-17-9)4-3-7-21-14-8-11(15(19)20)5-6-13(14)16/h5-6,8H,3-4,7H2,1-2H3,(H,17,18)(H,19,20)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a
University of the Pacific Curated by ChEMBL					Assay Description Binding affinity to transthyretin (unknown origin) by ITC method				J Med Chem 61: 7862-7876 (2018) Article DOI: 10.1021/acs.jmedchem.8b00817 BindingDB Entry DOI: 10.7270/Q2KP84SS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transthyretin (Homo sapiens (Human))	BDBM50197885 (CHEMBL3940890) Show SMILES Cc1n[nH]c(C)c1CCCOc1cc(ccc1F)C(O)=O Show InChI InChI=1S/C15H17FN2O3/c1-9-12(10(2)18-17-9)4-3-7-21-14-8-11(15(19)20)5-6-13(14)16/h5-6,8H,3-4,7H2,1-2H3,(H,17,18)(H,19,20)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a
Universidade de Coimbra Curated by ChEMBL					Assay Description Binding affinity to human plasma wild type TTR assessed as dissociation constants for second binding site of TTR by isothermal titration calorimetric...				Eur J Med Chem 121: 823-840 (2016) Article DOI: 10.1016/j.ejmech.2016.02.074 BindingDB Entry DOI: 10.7270/Q26975JG
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transthyretin (Homo sapiens (Human))	BDBM50225217 (5-(chloromethyl)-2-(2,4-dichlorophenoxy)phenol | C...) Show SMILES Oc1cc(CCl)ccc1Oc1ccc(Cl)cc1Cl Show InChI InChI=1S/C13H9Cl3O2/c14-7-8-1-3-13(11(17)5-8)18-12-4-2-9(15)6-10(12)16/h1-6,17H,7H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	5.70	n/a	n/a	n/a	4.4	n/a
Institute of Sciences Curated by ChEMBL					Assay Description Binding affinity to transthyretin at pH 4.4				J Med Chem 50: 5589-99 (2007) Article DOI: 10.1021/jm0700159 BindingDB Entry DOI: 10.7270/Q2PG1RGD
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transthyretin (Homo sapiens (Human))	BDBM50609726 (CHEMBL5276223) Show SMILES Oc1cc(O)c2C(=O)CC(Oc2c1)c1cc(Cl)cc(Cl)c1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50588575 (CHEMBL5203058) Show SMILES Oc1cc(F)cc(c1)C(=O)c1cc(O)c(O)c(c1)[N+]([O-])=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01195 BindingDB Entry DOI: 10.7270/Q27D304V
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50197885 (CHEMBL3940890) Show SMILES Cc1n[nH]c(C)c1CCCOc1cc(ccc1F)C(O)=O Show InChI InChI=1S/C15H17FN2O3/c1-9-12(10(2)18-17-9)4-3-7-21-14-8-11(15(19)20)5-6-13(14)16/h5-6,8H,3-4,7H2,1-2H3,(H,17,18)(H,19,20)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01423 BindingDB Entry DOI: 10.7270/Q2C251G9
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transthyretin (Homo sapiens (Human))	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | US10377729, Co...) Show SMILES OC(=O)c1ccc2nc(oc2c1)-c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C14H7Cl2NO3/c15-9-3-8(4-10(16)6-9)13-17-11-2-1-7(14(18)19)5-12(11)20-13/h1-6H,(H,18,19)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a
Universidade de Coimbra Curated by ChEMBL					Assay Description Binding affinity to recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as dissociation constants for first binding sit...				Eur J Med Chem 121: 823-840 (2016) Article DOI: 10.1016/j.ejmech.2016.02.074 BindingDB Entry DOI: 10.7270/Q26975JG
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transthyretin (Homo sapiens (Human))	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | US10377729, Co...) Show SMILES OC(=O)c1ccc2nc(oc2c1)-c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C14H7Cl2NO3/c15-9-3-8(4-10(16)6-9)13-17-11-2-1-7(14(18)19)5-12(11)20-13/h1-6H,(H,18,19)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	9.90	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01195 BindingDB Entry DOI: 10.7270/Q27D304V
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transthyretin (Homo sapiens (Human))	BDBM50609724 (CHEMBL5268339) Show SMILES Oc1cccc2OC(CC(=O)c12)c1cc(Cl)c(O)c(Cl)c1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50225224 (4-(2,4-dichlorophenoxy)-3-hydroxybenzaldehyde | CH...) Show SMILES Oc1cc(C=O)ccc1Oc1ccc(Cl)cc1Cl Show InChI InChI=1S/C13H8Cl2O3/c14-9-2-4-12(10(15)6-9)18-13-3-1-8(7-16)5-11(13)17/h1-7,17H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	13.9	n/a	n/a	n/a	4.4	n/a
Institute of Sciences Curated by ChEMBL					Assay Description Binding affinity to transthyretin at pH 4.4				J Med Chem 50: 5589-99 (2007) Article DOI: 10.1021/jm0700159 BindingDB Entry DOI: 10.7270/Q2PG1RGD
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transthyretin (Homo sapiens (Human))	BDBM50609723 (CHEMBL5283388) Show SMILES Oc1cc(O)c2C(=O)CC(Oc2c1)c1cc(Cl)c(O)c(Cl)c1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem		n/a	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576397 (7-(3,5-dimethyl-1H-pyrazol-4-yl)-1,3-benzothiazole...) Show SMILES Cc1n[nH]c(C)c1-c1cccc2ncsc12 |(2.13,2.02,;2.13,.48,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Affinity and Reversibility -The binding affinity and kinetics of binding were measured using Surface Plasmon Resonance based binding assay. These exp...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576398 (4-(3,5-dimethyl-1 H-pyrazol-4-yl)-7- ethyl-1,3-ben...) Show SMILES Cc1n[nH]c(C)c1-c1ccc(C)c2scnc12 |(2.13,2.02,;2.13,.48,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-4.98,1.48,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Affinity and Reversibility -The binding affinity and kinetics of binding were measured using Surface Plasmon Resonance based binding assay. These exp...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50108877 ((3,4-Dihydroxy-5-nitro-phenyl)-p-tolyl-methanone |...) Show SMILES Cc1ccc(cc1)C(=O)c1cc(O)c(O)c(c1)[N+]([O-])=O Show InChI InChI=1S/C14H11NO5/c1-8-2-4-9(5-3-8)13(17)10-6-11(15(19)20)14(18)12(16)7-10/h2-7,16,18H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a
University of the Pacific Curated by ChEMBL					Assay Description Binding affinity to transthyretin (unknown origin) by ITC method				J Med Chem 61: 7862-7876 (2018) Article DOI: 10.1021/acs.jmedchem.8b00817 BindingDB Entry DOI: 10.7270/Q2KP84SS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transthyretin (Homo sapiens (Human))	BDBM50609725 (CHEMBL5280970) Show SMILES Oc1ccc2C(=O)CC(Oc2c1)c1cc(Cl)c(O)c(Cl)c1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50588574 (CHEMBL5172990) Show SMILES Oc1cc(cc(c1O)[N+]([O-])=O)C(=O)c1cc(F)cc(F)c1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01195 BindingDB Entry DOI: 10.7270/Q27D304V
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50225228 (3-hydroxy-4-phenoxybenzoic acid | CHEMBL241454) Show SMILES OC(=O)c1ccc(Oc2ccccc2)c(O)c1 Show InChI InChI=1S/C13H10O4/c14-11-8-9(13(15)16)6-7-12(11)17-10-4-2-1-3-5-10/h1-8,14H,(H,15,16)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	27	n/a	n/a	n/a	4.4	n/a
Institute of Sciences Curated by ChEMBL					Assay Description Binding affinity to transthyretin at pH 4.4				J Med Chem 50: 5589-99 (2007) Article DOI: 10.1021/jm0700159 BindingDB Entry DOI: 10.7270/Q2PG1RGD
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM25406 (4-(2,4-dichlorophenoxy)-3-hydroxybenzoic acid | CH...) Show SMILES OC(=O)c1ccc(Oc2ccc(Cl)cc2Cl)c(O)c1 Show InChI InChI=1S/C13H8Cl2O4/c14-8-2-4-11(9(15)6-8)19-12-3-1-7(13(17)18)5-10(12)16/h1-6,16H,(H,17,18)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	27	n/a	n/a	n/a	4.4	n/a
Institute of Sciences Curated by ChEMBL					Assay Description Binding affinity to transthyretin at pH 4.4				J Med Chem 50: 5589-99 (2007) Article DOI: 10.1021/jm0700159 BindingDB Entry DOI: 10.7270/Q2PG1RGD
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576410 (4-(3,5-dimethyl-1H-pyrazol-4-yl)-6-fluoro-1,3-benz...) Show SMILES Cc1n[nH]c(C)c1-c1cc(F)cc2scnc12 |(2.13,2.02,;2.13,.48,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-2.69,3.54,;-3.51,1,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Affinity and Reversibility -The binding affinity and kinetics of binding were measured using Surface Plasmon Resonance based binding assay. These exp...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576403 (5-methyl-4-(7-methyl-1,3-benzothiazol-4-yl)-1H-pyr...) Show SMILES Cc1[nH]nc(C#N)c1-c1ccc(C)c2scnc12 |(.45,-3.14,;1.36,-1.89,;2.9,-1.89,;3.37,-.43,;2.13,.48,;2.13,2.02,;2.13,3.56,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-4.98,1.48,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Affinity and Reversibility -The binding affinity and kinetics of binding were measured using Surface Plasmon Resonance based binding assay. These exp...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM17636 (2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...) Show SMILES OC(=O)c1ccccc1Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C14H10F3NO2/c15-14(16,17)9-4-3-5-10(8-9)18-12-7-2-1-6-11(12)13(19)20/h1-8,18H,(H,19,20)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to wild type TTR (unknown origin) expressed in Escherichia coli BL21/DE3 by Circular dichroism spectroscopy				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00934 BindingDB Entry DOI: 10.7270/Q2CN77M6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transthyretin (Homo sapiens (Human))	BDBM50588571 (CHEMBL5172066) Show SMILES Oc1cc(cc(c1O)[N+]([O-])=O)C(=O)c1ccc(F)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01195 BindingDB Entry DOI: 10.7270/Q27D304V
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576409 (4-(3,5-dimethyl-1H-pyrazol-4-yl)-6-methoxy-1,3-ben...) Show SMILES COc1cc(-c2c(C)n[nH]c2C)c2ncsc2c1 |(-4.16,4.01,;-2.69,3.54,;-2.37,2.03,;-.91,1.55,;-.59,.05,;.88,-.43,;2.13,.48,;2.13,2.02,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;-1.73,-.98,;-1.73,-2.52,;-3.19,-3,;-4.1,-1.75,;-3.19,-.51,;-3.51,1,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Affinity and Reversibility -The binding affinity and kinetics of binding were measured using Surface Plasmon Resonance based binding assay. These exp...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50108877 ((3,4-Dihydroxy-5-nitro-phenyl)-p-tolyl-methanone |...) Show SMILES Cc1ccc(cc1)C(=O)c1cc(O)c(O)c(c1)[N+]([O-])=O Show InChI InChI=1S/C14H11NO5/c1-8-2-4-9(5-3-8)13(17)10-6-11(15(19)20)14(18)12(16)7-10/h2-7,16,18H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01195 BindingDB Entry DOI: 10.7270/Q27D304V
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transthyretin (Homo sapiens (Human))	BDBM50108877 ((3,4-Dihydroxy-5-nitro-phenyl)-p-tolyl-methanone |...) Show SMILES Cc1ccc(cc1)C(=O)c1cc(O)c(O)c(c1)[N+]([O-])=O Show InChI InChI=1S/C14H11NO5/c1-8-2-4-9(5-3-8)13(17)10-6-11(15(19)20)14(18)12(16)7-10/h2-7,16,18H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01195 BindingDB Entry DOI: 10.7270/Q27D304V
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transthyretin (Homo sapiens (Human))	BDBM576396 (4-(3,5-dimethyl-1H-pyrazol-4-yl)-1,3-benzothiazole...) Show SMILES Cc1n[nH]c(C)c1-c1cccc2scnc12 |(2.13,2.02,;2.13,.48,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Affinity and Reversibility -The binding affinity and kinetics of binding were measured using Surface Plasmon Resonance based binding assay. These exp...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576414 (7-(3,5-dimethyl-1 H-pyrazol-4-yl)[1,3]thiazolo[5,4...) Show SMILES Cc1n[nH]c(C)c1-c1ccnc2scnc12 |(2.13,2.02,;2.13,.48,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Affinity and Reversibility -The binding affinity and kinetics of binding were measured using Surface Plasmon Resonance based binding assay. These exp...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50225229 (2-(5-mercapto-1,3,4-oxadiazol-2-yl)phenol | CHEMBL...) Show SMILES Oc1ccccc1-c1nnc(S)o1 Show InChI InChI=1S/C8H6N2O2S/c11-6-4-2-1-3-5(6)7-9-10-8(13)12-7/h1-4,11H,(H,10,13)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	42	n/a	n/a	n/a	4.4	n/a
Institute of Sciences Curated by ChEMBL					Assay Description Binding affinity to transthyretin at pH 4.4				J Med Chem 50: 5589-99 (2007) Article DOI: 10.1021/jm0700159 BindingDB Entry DOI: 10.7270/Q2PG1RGD
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576399 (4-(3,5-dimethyl-1 H-pyrazol-4-yl)-7-(trifluoro eth...) Show SMILES Cc1n[nH]c(C)c1-c1ccc(c2scnc12)C(F)(F)F |(2.13,2.02,;2.13,.48,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,;-4.98,1.48,;-6.12,.44,;-5.3,2.98,;-4.66,-.03,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Affinity and Reversibility -The binding affinity and kinetics of binding were measured using Surface Plasmon Resonance based binding assay. These exp...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576400 (4-(3,5-dimethyl-1 H-pyrazol-4-yl)-1,3-benzothiazol...) Show SMILES Cc1n[nH]c(C)c1-c1ccc(C#N)c2scnc12 |(2.13,2.02,;2.13,.48,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-4.98,1.48,;-6.44,1.95,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Affinity and Reversibility -The binding affinity and kinetics of binding were measured using Surface Plasmon Resonance based binding assay. These exp...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50108877 ((3,4-Dihydroxy-5-nitro-phenyl)-p-tolyl-methanone |...) Show SMILES Cc1ccc(cc1)C(=O)c1cc(O)c(O)c(c1)[N+]([O-])=O Show InChI InChI=1S/C14H11NO5/c1-8-2-4-9(5-3-8)13(17)10-6-11(15(19)20)14(18)12(16)7-10/h2-7,16,18H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a
University of the Pacific Curated by ChEMBL					Assay Description Binding affinity to transthyretin V122I mutant (unknown origin) by ITC method				J Med Chem 61: 7862-7876 (2018) Article DOI: 10.1021/acs.jmedchem.8b00817 BindingDB Entry DOI: 10.7270/Q2KP84SS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transthyretin (Homo sapiens (Human))	BDBM576408 (4-(3,5-dimethyl- 1H-pyrazol-4-yl)-6-methyl-1,3-ben...) Show SMILES Cc1n[nH]c(C)c1-c1cc(C)cc2scnc12 |(2.13,2.02,;2.13,.48,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-2.69,3.54,;-3.51,1,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Affinity and Reversibility -The binding affinity and kinetics of binding were measured using Surface Plasmon Resonance based binding assay. These exp...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM13066 (2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...) Show SMILES OC(=O)Cc1ccccc1Nc1c(Cl)cccc1Cl Show InChI InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to wild type TTR (unknown origin) expressed in Escherichia coli BL21/DE3 by Circular dichroism spectroscopy				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00934 BindingDB Entry DOI: 10.7270/Q2CN77M6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transthyretin (Homo sapiens (Human))	BDBM36880 (2,2'-THIOBIS(4,6-DICHLOROPHENOL) | 2,4-dichlor...) Show SMILES Oc1c(Cl)cc(Cl)cc1Sc1cc(Cl)cc(Cl)c1O Show InChI InChI=1S/C12H6Cl4O2S/c13-5-1-7(15)11(17)9(3-5)19-10-4-6(14)2-8(16)12(10)18/h1-4,17-18H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to TTR V30M mutant (unknown origin) by isothermal titration calorimetry				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00823 BindingDB Entry DOI: 10.7270/Q2X63RR5
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM7459 (2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...) Show SMILES Oc1cc(O)c2c(c1)oc(cc2=O)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C15H10O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-6,16-19H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a
Ume£ University Curated by ChEMBL					Assay Description Binding affinity to TTR (unknown origin) by isothermal titration calorimetric analysis				J Med Chem 58: 6507-15 (2015) Article DOI: 10.1021/acs.jmedchem.5b00544 BindingDB Entry DOI: 10.7270/Q2P84DP1
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transthyretin (Homo sapiens (Human))	BDBM383210 (US10278929, Compound 1 | US11337935, Compound 1) Show SMILES OC(=O)c1ccc(cc1)-c1c(F)cccc1F Show InChI InChI=1S/C13H8F2O2/c14-10-2-1-3-11(15)12(10)8-4-6-9(7-5-8)13(16)17/h1-7H,(H,16,17)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	n/a	72.5	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description Dissociation Constants (Kd) associated with the binding of ligands to TTR are expressed in nM. Thermodynamic Binding Parameters associated with ligan...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2H70J43
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transthyretin (Homo sapiens (Human))	BDBM50601998 (CHEMBL5205181) Show SMILES Cc1n[nH]c(C)c1CCCOc1cc(OCCCCCCNCCOCCOCCN=[N+]=[N-])cc(c1)C(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01423 BindingDB Entry DOI: 10.7270/Q2C251G9
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576402 (4-(1,3-benzothiazol-4-yl)-5-methyl-1 H-pyrazole-3-...) Show SMILES Cc1[nH]nc(C#N)c1-c1cccc2scnc12 |(.45,-3.14,;1.36,-1.89,;2.9,-1.89,;3.37,-.43,;2.13,.48,;2.13,2.02,;2.13,3.56,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Affinity and Reversibility -The binding affinity and kinetics of binding were measured using Surface Plasmon Resonance based binding assay. These exp...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50240510 (CHEMBL898 | DIFLUNISAL) Show SMILES OC(=O)c1cc(ccc1O)-c1ccc(F)cc1F Show InChI InChI=1S/C13H8F2O3/c14-8-2-3-9(11(15)6-8)7-1-4-12(16)10(5-7)13(17)18/h1-6,16H,(H,17,18)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	DrugBank PDB Article PubMed	n/a	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to wild type TTR (unknown origin) expressed in Escherichia coli BL21/DE3 by Circular dichroism spectroscopy				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00934 BindingDB Entry DOI: 10.7270/Q2CN77M6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transthyretin (Homo sapiens (Human))	BDBM50588573 (CHEMBL5205412) Show SMILES Oc1cc(cc(c1O)[N+]([O-])=O)C(=O)c1cc(Cl)cc(Cl)c1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01195 BindingDB Entry DOI: 10.7270/Q27D304V
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50225219 (3-methoxy-4-phenoxybenzaldehyde | CHEMBL241453) Show SMILES COc1cc(C=O)ccc1Oc1ccccc1 Show InChI InChI=1S/C14H12O3/c1-16-14-9-11(10-15)7-8-13(14)17-12-5-3-2-4-6-12/h2-10H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	88	n/a	n/a	n/a	4.4	n/a
Institute of Sciences Curated by ChEMBL					Assay Description Binding affinity to transthyretin at pH 4.4				J Med Chem 50: 5589-99 (2007) Article DOI: 10.1021/jm0700159 BindingDB Entry DOI: 10.7270/Q2PG1RGD
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50459081 (CHEMBL4206443) Show SMILES Cc1n[nH]c(C)c1CCCOc1cc(ccc1I)C(O)=O Show InChI InChI=1S/C15H17IN2O3/c1-9-12(10(2)18-17-9)4-3-7-21-14-8-11(15(19)20)5-6-13(14)16/h5-6,8H,3-4,7H2,1-2H3,(H,17,18)(H,19,20)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a
University of the Pacific Curated by ChEMBL					Assay Description Binding affinity to transthyretin (unknown origin) by ITC method				J Med Chem 61: 7862-7876 (2018) Article DOI: 10.1021/acs.jmedchem.8b00817 BindingDB Entry DOI: 10.7270/Q2KP84SS
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50108877 ((3,4-Dihydroxy-5-nitro-phenyl)-p-tolyl-methanone |...) Show SMILES Cc1ccc(cc1)C(=O)c1cc(O)c(O)c(c1)[N+]([O-])=O Show InChI InChI=1S/C14H11NO5/c1-8-2-4-9(5-3-8)13(17)10-6-11(15(19)20)14(18)12(16)7-10/h2-7,16,18H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to TTR V30M mutant (unknown origin) by isothermal titration calorimetry				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00823 BindingDB Entry DOI: 10.7270/Q2X63RR5
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transthyretin (Homo sapiens (Human))	BDBM50110590 (2,2-Dimethyl-5-(2,5-dimethylphenoxy)valeriansaeure...) Show SMILES Cc1ccc(C)c(OCCCC(C)(C)C(O)=O)c1 Show InChI InChI=1S/C15H22O3/c1-11-6-7-12(2)13(10-11)18-9-5-8-15(3,4)14(16)17/h6-7,10H,5,8-9H2,1-4H3,(H,16,17)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a
Ume£ University Curated by ChEMBL					Assay Description Binding affinity to TTR (unknown origin) by isothermal titration calorimetric analysis				J Med Chem 58: 6507-15 (2015) Article DOI: 10.1021/acs.jmedchem.5b00544 BindingDB Entry DOI: 10.7270/Q2P84DP1
					More data for this Ligand-Target Pair				3D Structure (crystal)

Displayed 1 to 50 (of 124 total )  |  Next  |  Last  >>

Jump to: