| Reaction Details |
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 | Report a problem with these data |
| Target | Transthyretin |
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| Ligand | BDBM13066 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2055585 (CHEMBL4710586) |
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| Kd | 60±n/a nM |
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| Citation |  Yokoyama, T; Mizuguchi, M Transthyretin Amyloidogenesis Inhibitors: From Discovery to Current Developments. J Med Chem63:14228-14242 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Transthyretin |
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| Name: | Transthyretin |
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| Synonyms: | ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR) |
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| Type: | Enzyme |
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| Mol. Mass.: | 15884.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P02766 |
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| Residue: | 147 |
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| Sequence: | MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDT
WEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDS
GPRRYTIAALLSPYSYSTTAVVTNPKE
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| BDBM13066 |
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| n/a |
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| Name | BDBM13066 |
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| Synonyms: | 2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid | CHEMBL139 | Diclofenac | US11337935, Compound Diclofenac | US11478464, Compound Diclofenac | US11786535, Compound Diclofenac | {2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C14H11Cl2NO2 |
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| Mol. Mass. | 296.149 |
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| SMILES | OC(=O)Cc1ccccc1Nc1c(Cl)cccc1Cl |
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| Structure | 
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