Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511610 (US11059801, Compound dBET18) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.57 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM50544938 (CHEMBL4094346 | US11059801, Compound dBET1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | 3.09 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511611 (US11059801, Compound dBET19) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.62 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511608 (US11059801, Compound dBET16) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.84 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511621 (US11059801, Compound dBET29) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.05 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511609 (US11059801, Compound dBET17) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.41 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 [49-170]/DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511627 (US11059801, Compound dBET35) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.21 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511594 (US11059801, Compound dBET2) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511616 (US11059801, Compound dBET24) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 10.3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511595 (US11059801, Compound dBET3) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 10.4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511605 (US11059801, Compound dBET13) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 10.7 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 [49-170]/DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511610 (US11059801, Compound dBET18) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511664 (US11059801, Compound D-31) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12.1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511606 (US11059801, Compound dBET14) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12.4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511602 (US11059801, Compound dBET10) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12.7 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 [49-170]/DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511629 (US11059801, Compound dBET37) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | 13.2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 [49-170]/DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511598 (US11059801, Compound dBET6) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511601 (US11059801, Compound dBET9) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 14.8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 [49-170]/DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511601 (US11059801, Compound dBET9) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511663 (US11059801, Compound D-30) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 15.2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511620 (US11059801, Compound dBET28) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 17.1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 [49-170]/DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM50544938 (CHEMBL4094346 | US11059801, Compound dBET1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511665 (US11059801, Compound D-32) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 21.4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511604 (US11059801, Compound dBET12) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 23.8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 [49-170]/DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511634 (US11059801, Compound dBET43) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 24.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511603 (US11059801, Compound dBET11) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 25.1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511652 (US11059801, Compound D-18) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 25.3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511622 (US11059801, Compound dBET30) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 26.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511623 (US11059801, Compound dBET31) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 26.8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511615 (US11059801, Compound dBET23) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | 26.9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 [49-170]/DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511633 (US11059801, Compound dBET42) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 26.9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511614 (US11059801, Compound dBET22) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 28.4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511638 (US11059801, Compound D-1 | US11059801, Compound D-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | 28.9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 [49-170]/DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511635 (US11059801, Compound dBET44) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 [49-170]/DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511607 (US11059801, Compound dBET15) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 [49-170]/DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511630 (US11059801, Compound dBET38) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 31.4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 [49-170]/DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511595 (US11059801, Compound dBET3) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 [49-170]/DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511597 (US11059801, Compound dBET5) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511600 (US11059801, Compound dBET8) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 37.2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511613 (US11059801, Compound dBET21) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511661 (US11059801, Compound D-28) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 40.1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511607 (US11059801, Compound dBET15) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 40.4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511619 (US11059801, Compound dBET27) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 41.1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 [49-170]/DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511609 (US11059801, Compound dBET17) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511658 (US11059801, Compound D-25) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 58.9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 [49-170]/DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511632 (US11059801, Compound dBET41) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 62.8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM65456 (19171-19-8 | 4-amino-2-(2,6-dioxopiperidin-3-yl)is...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid PDB UniChem | US Patent | n/a | n/a | 63.1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511650 (US11059801, Compound D-16) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | 71.4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 [49-170]/DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511628 (US11059801, Compound dBET36) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 80.3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 [49-170]/DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human)) | BDBM511602 (US11059801, Compound dBET10) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-... | Citation and Details BindingDB Entry DOI: 10.7270/Q2G44TFM | |||||||||||
More data for this Ligand-Target Pair |
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