Compile Data Set for Download or QSAR

Found 232 hits Enz. Inhib. hit(s) with all data for entry = 10163   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384427 (US10590114, No. 122 | US11111235, Compound 122 | U...) Show SMILES CNc1nc(Nc2cn(nc2C2CC2)C2(C)CCOC2=O)ncc1C(F)(F)F Show InChI InChI=1S/C17H19F3N6O2/c1-16(5-6-28-14(16)27)26-8-11(12(25-26)9-3-4-9)23-15-22-7-10(17(18,19)20)13(21-2)24-15/h7-9H,3-6H2,1-2H3,(H2,21,22,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.720	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384405 (US10590114, No. 108 | US11111235, No. 91 | US11591...) Show SMILES CCNc1nc(Nc2cn(nc2C2CC2)C2(C)CCOC2=O)ncc1C(F)(F)F Show InChI InChI=1S/C18H21F3N6O2/c1-3-22-14-11(18(19,20)21)8-23-16(25-14)24-12-9-27(26-13(12)10-4-5-10)17(2)6-7-29-15(17)28/h8-10H,3-7H2,1-2H3,(H2,22,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.960	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384428 (US10590114, No. 115 | US11111235, Compound 114 | U...) Show SMILES CCNc1nc(Nc2cn(nc2C2CC2)C2(C)CCOC2=O)ncc1Br Show InChI InChI=1S/C17H21BrN6O2/c1-3-19-14-11(18)8-20-16(22-14)21-12-9-24(23-13(12)10-4-5-10)17(2)6-7-26-15(17)25/h8-10H,3-7H2,1-2H3,(H2,19,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.05	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384457 (US10590114, No. 144 | US11111235, Compound 143 | U...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C2(C)CCOC2=O)ncc1C(F)(F)F Show InChI InChI=1S/C18H21F3N6O2/c1-3-22-14-11(18(19,20)21)9-23-16(25-14)24-13-8-12(26-27(13)10-4-5-10)17(2)6-7-29-15(17)28/h8-10H,3-7H2,1-2H3,(H2,22,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.21	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384464 (US10590114, No. 151 | US11111235, Compound 150 | U...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C2(C)CCOC2=O)ncc1Br Show InChI InChI=1S/C17H21BrN6O2/c1-3-19-14-11(18)9-20-16(22-14)21-13-8-12(23-24(13)10-4-5-10)17(2)6-7-26-15(17)25/h8-10H,3-7H2,1-2H3,(H2,19,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.22	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384485 (US10590114, No. 172 | US11111235, Compound 172 | U...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C2(C)CCn3ncnc23)ncc1C(F)(F)F Show InChI InChI=1S/C19H22F3N9/c1-3-23-15-12(19(20,21)22)9-24-17(28-15)27-14-8-13(29-31(14)11-4-5-11)18(2)6-7-30-16(18)25-10-26-30/h8-11H,3-7H2,1-2H3,(H2,23,24,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.47	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384432 (US10590114, No. 118 | US11111235, Compound 118 | U...) Show SMILES CCNc1nc(Nc2cn(nc2C2CC2)C(C)(C)C#N)ncc1C(F)(F)F Show InChI InChI=1S/C17H20F3N7/c1-4-22-14-11(17(18,19)20)7-23-15(25-14)24-12-8-27(16(2,3)9-21)26-13(12)10-5-6-10/h7-8,10H,4-6H2,1-3H3,(H2,22,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.55	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384432 (US10590114, No. 118 | US11111235, Compound 118 | U...) Show SMILES CCNc1nc(Nc2cn(nc2C2CC2)C(C)(C)C#N)ncc1C(F)(F)F Show InChI InChI=1S/C17H20F3N7/c1-4-22-14-11(17(18,19)20)7-23-15(25-14)24-12-8-27(16(2,3)9-21)26-13(12)10-5-6-10/h7-8,10H,4-6H2,1-3H3,(H2,22,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.55	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384407 (US10590114, No. 93 | US11111235, No. 93 | US115913...) Show SMILES CCNc1nc(Nc2cn(nc2C2CC2)C(C)(C)C#N)ncc1Br Show InChI InChI=1S/C16H20BrN7/c1-4-19-14-11(17)7-20-15(22-14)21-12-8-24(16(2,3)9-18)23-13(12)10-5-6-10/h7-8,10H,4-6H2,1-3H3,(H2,19,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.87	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384469 (US10590114, No. 156 | US11111235, Compound 155 | U...) Show SMILES CNc1nc(Nc2cc(nn2C2CC2)C2(C)CCOC2=O)ncc1C(F)(F)F Show InChI InChI=1S/C17H19F3N6O2/c1-16(5-6-28-14(16)27)11-7-12(26(25-11)9-3-4-9)23-15-22-8-10(17(18,19)20)13(21-2)24-15/h7-9H,3-6H2,1-2H3,(H2,21,22,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.95	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384382 (US10590114, No. 71 | US11111235, No. 69 | US115913...) Show SMILES Cn1nc(cc1Nc1ncc(c(NC2CC2)n1)C(F)(F)F)C(C)(C)n1nccn1 Show InChI InChI=1S/C17H20F3N9/c1-16(2,29-22-6-7-23-29)12-8-13(28(3)27-12)25-15-21-9-11(17(18,19)20)14(26-15)24-10-4-5-10/h6-10H,4-5H2,1-3H3,(H2,21,24,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.23	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384347 (BDBM384370 | US10590114, No. 70 | US11111235, No. ...) Show SMILES CCNc1nc(Nc2cc(nn2C)C(C)(C)n2nccn2)ncc1C(F)(F)F Show InChI InChI=1S/C16H20F3N9/c1-5-20-13-10(16(17,18)19)9-21-14(25-13)24-12-8-11(26-27(12)4)15(2,3)28-22-6-7-23-28/h6-9H,5H2,1-4H3,(H2,20,21,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.31	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384330 (US10590114, No. 27 | US11111235, No. 27 | US115913...) Show SMILES CCNc1nc(Nc2cnn(C3C[C@@H](C3)C#N)c2C)ncc1C(F)(F)F |r,wU:13.15,(5.42,.28,;4.09,1.05,;4.09,2.59,;2.75,3.36,;1.42,2.59,;.08,3.36,;-1.25,2.59,;-1.25,1.05,;-0,.14,;-.48,-1.32,;-2.02,-1.32,;-2.79,-2.65,;-4.28,-3.05,;-3.88,-4.54,;-2.39,-4.14,;-4.65,-5.87,;-5.42,-7.21,;-2.5,.14,;-3.98,.54,;.08,4.9,;1.42,5.67,;2.75,4.9,;4.09,5.67,;5.42,4.9,;4.09,7.21,;5.42,6.44,)| Show InChI InChI=1S/C16H18F3N7/c1-3-21-14-12(16(17,18)19)7-22-15(25-14)24-13-8-23-26(9(13)2)11-4-10(5-11)6-20/h7-8,10-11H,3-5H2,1-2H3,(H2,21,22,24,25)/t10-,11?	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.41	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384392 (US10590114, No. 78 | US11111235, No. 78 | US115913...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C(C)(C)n2nccn2)ncc1C(F)(F)F Show InChI InChI=1S/C18H22F3N9/c1-4-22-15-12(18(19,20)21)10-23-16(27-15)26-14-9-13(28-29(14)11-5-6-11)17(2,3)30-24-7-8-25-30/h7-11H,4-6H2,1-3H3,(H2,22,23,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.69	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384455 (US10590114, No. 141 | US11111235, Compound 141 | U...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C(C)(C)C#N)ncc1Br Show InChI InChI=1S/C16H20BrN7/c1-4-19-14-11(17)8-20-15(22-14)21-13-7-12(16(2,3)9-18)23-24(13)10-5-6-10/h7-8,10H,4-6H2,1-3H3,(H2,19,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.94	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384445 (US10590114, No. 131 | US11111235, Compound 131 | U...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C(C)(C)C#N)ncc1C(F)(F)F Show InChI InChI=1S/C17H20F3N7/c1-4-22-14-11(17(18,19)20)8-23-15(25-14)24-13-7-12(16(2,3)9-21)26-27(13)10-5-6-10/h7-8,10H,4-6H2,1-3H3,(H2,22,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.98	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384310 (US10590114, No. 14 | US11111235, No. 14 | US115913...) Show SMILES CNc1nc(Nc2cn(nc2C)C(C)(C)c2ncn(C)n2)ncc1C(F)(F)F Show InChI InChI=1S/C16H20F3N9/c1-9-11(7-28(25-9)15(2,3)13-22-8-27(5)26-13)23-14-21-6-10(16(17,18)19)12(20-4)24-14/h6-8H,1-5H3,(H2,20,21,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.91	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384404 (US10590114, No. 102 | US11111235, No. 90 | US11591...) Show SMILES COc1nc(Nc2cn(nc2C)C2(C)CCOC2=O)ncc1Br Show InChI InChI=1S/C14H16BrN5O3/c1-8-10(17-13-16-6-9(15)11(18-13)22-3)7-20(19-8)14(2)4-5-23-12(14)21/h6-7H,4-5H2,1-3H3,(H,16,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384417 (US10590114, No. 120 | US11111235, No. 120 | US1159...) Show SMILES Cc1nn(cc1Nc1ncc(c(n1)C1CC1)C(F)(F)F)C1(C)CCOC1=O Show InChI InChI=1S/C17H18F3N5O2/c1-9-12(8-25(24-9)16(2)5-6-27-14(16)26)22-15-21-7-11(17(18,19)20)13(23-15)10-3-4-10/h7-8,10H,3-6H2,1-2H3,(H,21,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384405 (US10590114, No. 108 | US11111235, No. 91 | US11591...) Show SMILES CCNc1nc(Nc2cn(nc2C2CC2)C2(C)CCOC2=O)ncc1C(F)(F)F Show InChI InChI=1S/C18H21F3N6O2/c1-3-22-14-11(18(19,20)21)8-23-16(25-14)24-12-9-27(26-13(12)10-4-5-10)17(2)6-7-29-15(17)28/h8-10H,3-7H2,1-2H3,(H2,22,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384419 (US10590114, No. 105 | US11111235, No. 105 | US1159...) Show SMILES CCNc1nc(Nc2cnn(c2C2CC2)-c2cnccn2)ncc1C(F)(F)F Show InChI InChI=1S/C17H17F3N8/c1-2-22-15-11(17(18,19)20)7-24-16(27-15)26-12-8-25-28(14(12)10-3-4-10)13-9-21-5-6-23-13/h5-10H,2-4H2,1H3,(H2,22,24,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384420 (US10590114, No. 121 | US11111235, No. 121 | US1159...) Show SMILES CCNc1nc(Nc2cnn(C3C[C@@H](C3)N3CCN(CC(F)F)CC3)c2C)ncc1C(F)(F)F |r,wU:13.15,(6.19,2.95,;4.86,3.72,;4.86,5.26,;3.52,6.03,;2.19,5.26,;.85,6.03,;-.48,5.26,;-.48,3.72,;.77,2.81,;.29,1.35,;-1.25,1.35,;-2.02,.01,;-3.51,-.39,;-3.11,-1.87,;-1.62,-1.48,;-3.88,-3.21,;-5.42,-3.21,;-6.19,-4.54,;-5.42,-5.87,;-6.19,-7.21,;-5.42,-8.54,;-6.19,-9.88,;-3.88,-8.54,;-3.88,-5.87,;-3.11,-4.54,;-1.73,2.81,;-3.21,3.21,;.85,7.57,;2.19,8.34,;3.52,7.57,;4.86,8.34,;4.86,9.88,;6.19,7.57,;6.19,9.11,)| Show InChI InChI=1S/C21H29F5N8/c1-3-27-19-16(21(24,25)26)10-28-20(31-19)30-17-11-29-34(13(17)2)15-8-14(9-15)33-6-4-32(5-7-33)12-18(22)23/h10-11,14-15,18H,3-9,12H2,1-2H3,(H2,27,28,30,31)/t14-,15?	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384421 (US10590114, No. 107 | US11111235, No. 107 | US1159...) Show SMILES CCNc1nc(Nc2cn(nc2C2CC2)C2C[C@@H]2C#N)ncc1C(F)(F)F |r| Show InChI InChI=1S/C17H18F3N7/c1-2-22-15-11(17(18,19)20)7-23-16(25-15)24-12-8-27(13-5-10(13)6-21)26-14(12)9-3-4-9/h7-10,13H,2-5H2,1H3,(H2,22,23,24,25)/t10-,13?/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384405 (US10590114, No. 108 | US11111235, No. 91 | US11591...) Show SMILES CCNc1nc(Nc2cn(nc2C2CC2)C2(C)CCOC2=O)ncc1C(F)(F)F Show InChI InChI=1S/C18H21F3N6O2/c1-3-22-14-11(18(19,20)21)8-23-16(25-14)24-12-9-27(26-13(12)10-4-5-10)17(2)6-7-29-15(17)28/h8-10H,3-7H2,1-2H3,(H2,22,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384423 (US10590114, No. 109 | US11111235, No. 109 | US1159...) Show SMILES CNc1nc(Nc2c[nH]nc2C)ncc1C(F)(F)F Show InChI InChI=1S/C10H11F3N6/c1-5-7(4-16-19-5)17-9-15-3-6(10(11,12)13)8(14-2)18-9/h3-4H,1-2H3,(H,16,19)(H2,14,15,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384424 (US10590114, No. 110 | US11111235, No. 110 | US1159...) Show SMILES CCNc1nc(Nc2cn(nc2C2CC2)C2CS(=O)(=O)C2)ncc1C(F)(F)F Show InChI InChI=1S/C16H19F3N6O2S/c1-2-20-14-11(16(17,18)19)5-21-15(23-14)22-12-6-25(10-7-28(26,27)8-10)24-13(12)9-3-4-9/h5-6,9-10H,2-4,7-8H2,1H3,(H2,20,21,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384425 (US10590114, No. 111 | US11111235, No. 111 | US1159...) Show SMILES CCNc1nc(Nc2cn(nc2C2CC2)S(C)(=O)=O)ncc1Br Show InChI InChI=1S/C13H17BrN6O2S/c1-3-15-12-9(14)6-16-13(18-12)17-10-7-20(23(2,21)22)19-11(10)8-4-5-8/h6-8H,3-5H2,1-2H3,(H2,15,16,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384426 (US10590114, No. 112 | US11111235, No. 112 | US1159...) Show SMILES CCNc1nc(Nc2cn(nc2C2CC2)S(C)(=O)=O)ncc1C(F)(F)F Show InChI InChI=1S/C14H17F3N6O2S/c1-3-18-12-9(14(15,16)17)6-19-13(21-12)20-10-7-23(26(2,24)25)22-11(10)8-4-5-8/h6-8H,3-5H2,1-2H3,(H2,18,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384427 (US10590114, No. 122 | US11111235, Compound 122 | U...) Show SMILES CNc1nc(Nc2cn(nc2C2CC2)C2(C)CCOC2=O)ncc1C(F)(F)F Show InChI InChI=1S/C17H19F3N6O2/c1-16(5-6-28-14(16)27)26-8-11(12(25-26)9-3-4-9)23-15-22-7-10(17(18,19)20)13(21-2)24-15/h7-9H,3-6H2,1-2H3,(H2,21,22,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384428 (US10590114, No. 115 | US11111235, Compound 114 | U...) Show SMILES CCNc1nc(Nc2cn(nc2C2CC2)C2(C)CCOC2=O)ncc1Br Show InChI InChI=1S/C17H21BrN6O2/c1-3-19-14-11(18)8-20-16(22-14)21-12-9-24(23-13(12)10-4-5-10)17(2)6-7-26-15(17)25/h8-10H,3-7H2,1-2H3,(H2,19,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384428 (US10590114, No. 115 | US11111235, Compound 114 | U...) Show SMILES CCNc1nc(Nc2cn(nc2C2CC2)C2(C)CCOC2=O)ncc1Br Show InChI InChI=1S/C17H21BrN6O2/c1-3-19-14-11(18)8-20-16(22-14)21-12-9-24(23-13(12)10-4-5-10)17(2)6-7-26-15(17)25/h8-10H,3-7H2,1-2H3,(H2,19,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384406 (US10590114, No. 116 | US11111235, No. 92 | US11591...) Show SMILES CCNc1nc(Nc2cnn(C3CCCN(CC(F)F)C3)c2C)ncc1C(F)(F)F Show InChI InChI=1S/C18H24F5N7/c1-3-24-16-13(18(21,22)23)7-25-17(28-16)27-14-8-26-30(11(14)2)12-5-4-6-29(9-12)10-15(19)20/h7-8,12,15H,3-6,9-10H2,1-2H3,(H2,24,25,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384431 (US10590114, No. 117 | US11111235, No. 117 | US1159...) Show SMILES CCNc1nc(Nc2cn(nc2Cl)C2(C)CCOC2=O)ncc1C(F)(F)F Show InChI InChI=1S/C15H16ClF3N6O2/c1-3-20-11-8(15(17,18)19)6-21-13(23-11)22-9-7-25(24-10(9)16)14(2)4-5-27-12(14)26/h6-7H,3-5H2,1-2H3,(H2,20,21,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384432 (US10590114, No. 118 | US11111235, Compound 118 | U...) Show SMILES CCNc1nc(Nc2cn(nc2C2CC2)C(C)(C)C#N)ncc1C(F)(F)F Show InChI InChI=1S/C17H20F3N7/c1-4-22-14-11(17(18,19)20)7-23-15(25-14)24-12-8-27(16(2,3)9-21)26-13(12)10-5-6-10/h7-8,10H,4-6H2,1-3H3,(H2,22,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384433 (US10590114, No. 124 | US11111235, No. 124 | US1159...) Show SMILES CNc1nc(Nc2cn(nc2C)C2(C)CCOC2=O)ncc1C(F)(F)F Show InChI InChI=1S/C15H17F3N6O2/c1-8-10(7-24(23-8)14(2)4-5-26-12(14)25)21-13-20-6-9(15(16,17)18)11(19-3)22-13/h6-7H,4-5H2,1-3H3,(H2,19,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384417 (US10590114, No. 120 | US11111235, No. 120 | US1159...) Show SMILES Cc1nn(cc1Nc1ncc(c(n1)C1CC1)C(F)(F)F)C1(C)CCOC1=O Show InChI InChI=1S/C17H18F3N5O2/c1-9-12(8-25(24-9)16(2)5-6-27-14(16)26)22-15-21-7-11(17(18,19)20)13(23-15)10-3-4-10/h7-8,10H,3-6H2,1-2H3,(H,21,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384420 (US10590114, No. 121 | US11111235, No. 121 | US1159...) Show SMILES CCNc1nc(Nc2cnn(C3C[C@@H](C3)N3CCN(CC(F)F)CC3)c2C)ncc1C(F)(F)F |r,wU:13.15,(6.19,2.95,;4.86,3.72,;4.86,5.26,;3.52,6.03,;2.19,5.26,;.85,6.03,;-.48,5.26,;-.48,3.72,;.77,2.81,;.29,1.35,;-1.25,1.35,;-2.02,.01,;-3.51,-.39,;-3.11,-1.87,;-1.62,-1.48,;-3.88,-3.21,;-5.42,-3.21,;-6.19,-4.54,;-5.42,-5.87,;-6.19,-7.21,;-5.42,-8.54,;-6.19,-9.88,;-3.88,-8.54,;-3.88,-5.87,;-3.11,-4.54,;-1.73,2.81,;-3.21,3.21,;.85,7.57,;2.19,8.34,;3.52,7.57,;4.86,8.34,;4.86,9.88,;6.19,7.57,;6.19,9.11,)| Show InChI InChI=1S/C21H29F5N8/c1-3-27-19-16(21(24,25)26)10-28-20(31-19)30-17-11-29-34(13(17)2)15-8-14(9-15)33-6-4-32(5-7-33)12-18(22)23/h10-11,14-15,18H,3-9,12H2,1-2H3,(H2,27,28,30,31)/t14-,15?	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384427 (US10590114, No. 122 | US11111235, Compound 122 | U...) Show SMILES CNc1nc(Nc2cn(nc2C2CC2)C2(C)CCOC2=O)ncc1C(F)(F)F Show InChI InChI=1S/C17H19F3N6O2/c1-16(5-6-28-14(16)27)26-8-11(12(25-26)9-3-4-9)23-15-22-7-10(17(18,19)20)13(21-2)24-15/h7-9H,3-6H2,1-2H3,(H2,21,22,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384413 (US10590114, No. 123 | US11111235, No. 99 | US11591...) Show SMILES CNc1nc(Nc2cn(nc2Cl)C2(C)CCOC2=O)ncc1C(F)(F)F Show InChI InChI=1S/C14H14ClF3N6O2/c1-13(3-4-26-11(13)25)24-6-8(9(15)23-24)21-12-20-5-7(14(16,17)18)10(19-2)22-12/h5-6H,3-4H2,1-2H3,(H2,19,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384433 (US10590114, No. 124 | US11111235, No. 124 | US1159...) Show SMILES CNc1nc(Nc2cn(nc2C)C2(C)CCOC2=O)ncc1C(F)(F)F Show InChI InChI=1S/C15H17F3N6O2/c1-8-10(7-24(23-8)14(2)4-5-26-12(14)25)21-13-20-6-9(15(16,17)18)11(19-3)22-13/h6-7H,4-5H2,1-3H3,(H2,19,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384414 (US10590114, No. 125 | US11111235, No. 100 | US1159...) Show SMILES CCNc1nc(Nc2cn(nc2C)C2(C)CCOC2=O)ncc1C(F)(F)F Show InChI InChI=1S/C16H19F3N6O2/c1-4-20-12-10(16(17,18)19)7-21-14(23-12)22-11-8-25(24-9(11)2)15(3)5-6-27-13(15)26/h7-8H,4-6H2,1-3H3,(H2,20,21,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384440 (US10590114, No. 126 | US11111235, No. 126 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C(C)(C)n2nccn2)ncc1Br Show InChI InChI=1S/C17H22BrN9/c1-4-19-15-12(18)10-20-16(24-15)23-14-9-13(25-26(14)11-5-6-11)17(2,3)27-21-7-8-22-27/h7-11H,4-6H2,1-3H3,(H2,19,20,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384392 (US10590114, No. 78 | US11111235, No. 78 | US115913...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C(C)(C)n2nccn2)ncc1C(F)(F)F Show InChI InChI=1S/C18H22F3N9/c1-4-22-15-12(18(19,20)21)10-23-16(27-15)26-14-9-13(28-29(14)11-5-6-11)17(2,3)30-24-7-8-25-30/h7-11H,4-6H2,1-3H3,(H2,22,23,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384442 (US10590114, No. 128 | US11111235, No. 128 | US1159...) Show SMILES CNc1nc(Nc2cc(nn2C2CC2)C(C)(C)c2ncccn2)ncc1C(F)(F)F Show InChI InChI=1S/C19H21F3N8/c1-18(2,16-24-7-4-8-25-16)13-9-14(30(29-13)11-5-6-11)27-17-26-10-12(19(20,21)22)15(23-3)28-17/h4,7-11H,5-6H2,1-3H3,(H2,23,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384402 (US10590114, No. 129 | US11111235, No. 88 | US11591...) Show SMILES CCNc1nc(Nc2cc(nn2CC)C(C)(C)n2nccn2)ncc1C(F)(F)F Show InChI InChI=1S/C17H22F3N9/c1-5-21-14-11(17(18,19)20)10-22-15(26-14)25-13-9-12(27-28(13)6-2)16(3,4)29-23-7-8-24-29/h7-10H,5-6H2,1-4H3,(H2,21,22,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384444 (US10590114, No. 130 | US11111235, No. 130 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C(=O)N(C)C)ncc1C(F)(F)F Show InChI InChI=1S/C16H20F3N7O/c1-4-20-13-10(16(17,18)19)8-21-15(23-13)22-12-7-11(14(27)25(2)3)24-26(12)9-5-6-9/h7-9H,4-6H2,1-3H3,(H2,20,21,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384445 (US10590114, No. 131 | US11111235, Compound 131 | U...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C(C)(C)C#N)ncc1C(F)(F)F Show InChI InChI=1S/C17H20F3N7/c1-4-22-14-11(17(18,19)20)8-23-15(25-14)24-13-7-12(16(2,3)9-21)26-27(13)10-5-6-10/h7-8,10H,4-6H2,1-3H3,(H2,22,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384446 (US10590114, No. 132 | US11111235, No. 132 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)S(C)(=O)=O)ncc1C(F)(F)F Show InChI InChI=1S/C14H17F3N6O2S/c1-3-18-12-9(14(15,16)17)7-19-13(21-12)20-10-6-11(26(2,24)25)22-23(10)8-4-5-8/h6-8H,3-5H2,1-2H3,(H2,18,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384448 (US10590114, No. 134 | US11111235, No. 134 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C(C)(C)O)ncc1C(F)(F)F Show InChI InChI=1S/C16H21F3N6O/c1-4-20-13-10(16(17,18)19)8-21-14(23-13)22-12-7-11(15(2,3)26)24-25(12)9-5-6-9/h7-9,26H,4-6H2,1-3H3,(H2,20,21,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384451 (US10590114, No. 138 | US11111235, No. 138 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C(C)n2nccn2)ncc1C(F)(F)F Show InChI InChI=1S/C17H20F3N9/c1-3-21-15-12(17(18,19)20)9-22-16(26-15)25-14-8-13(27-28(14)11-4-5-11)10(2)29-23-6-7-24-29/h6-11H,3-5H2,1-2H3,(H2,21,22,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Materials:LRRK2 G2019S enzymeSubstrate (LRRKtide)ATPTR-FRET dilution bufferpLRRKtide antibody384-well assay plateDMSOEnzyme Reaction Conditions50 mM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84G2S
					More data for this Ligand-Target Pair

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