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Compile Data Set for Download or QSAR

Found 291 hits Enz. Inhib. hit(s) with all data for entry = 10511   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542862
PNG
(4-(3-((2-(4-(difluoromethoxy)phenyl)-8-methoxy-2,3...)
Show SMILES COc1cc(Cc2cnc3cc(cnn23)C#CC(C)(C)N)cc2OCC(Oc12)c1ccc(OC(F)F)cc1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542881
PNG
(3-((2-(6-ethoxypyridin-3-yl)-8-methoxy-2,3- dihydr...)
Show SMILES CCOc1ccc(cn1)C1COc2cc(Cc3c[nH]c4ncccc34)cc(OC)c2O1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542814
PNG
(4-(3-((8-methoxy-2-(6-methoxypyridin-3-yl)-2,3- di...)
Show SMILES COc1ccc(cn1)C1COc2cc(Cc3cnn4cc(cnc34)N3CCOCC3)cc(OC)c2O1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542815
PNG
(6-methoxy-3-((8-methoxy-2-(6-methoxypyridin-3-yl)-...)
Show SMILES COc1cnc2c(Cc3cc(OC)c4OC(COc4c3)c3ccc(OC)nc3)cnn2c1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542818
PNG
(4-(3-((8-methoxy-2-(6-methoxypyridin-3-yl)-2,3- di...)
Show SMILES COc1ccc(cn1)C1COc2cc(Cc3cnc4cc(cnn34)C#CC(C)(C)N)cc(OC)c2O1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542819
PNG
(4-(3-((8-methoxy-2-(6-methoxypyridin-3-yl)-2,3- di...)
Show SMILES COc1ccc(cn1)C1COc2cc(Cc3cnc4cc(cnn34)N3CCOCC3)cc(OC)c2O1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542824
PNG
(3-((8-methoxy-2-(6-methoxypyridin-3-yl)-2,3- dihyd...)
Show SMILES COc1ccc(cn1)C1COc2cc(Cc3c[nH]c4ncccc34)cc(OC)c2O1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542847
PNG
(3-((2-(6-ethylpyridin-3-yl)-8-methoxy-2,3- dihydro...)
Show SMILES CCc1ccc(cn1)C1COc2cc(Cc3cnn4cc(OC)cnc34)cc(OC)c2O1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542975
PNG
(3-(3-methoxy-4-((6-methoxypyridin-3-yl)methoxy)ben...)
Show SMILES COc1ccc(COc2ccc(Cn3cnc4cc(cnc34)C#CC3CCNC3)cc2OC)cn1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542551
PNG
(3-((2-(4-methoxyphenyl)-2,3-dihydrobenzo[b][1,4]di...)
Show SMILES COc1ccc(cc1)C1COc2cc(Cn3cnc4cc(cnc34)-c3cnn(C)c3)ccc2O1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542721
PNG
(4-(3-((2-(6-methoxypyridin-3-yl)-2,3- dihydrobenzo...)
Show SMILES COc1ccc(cn1)C1COc2cc(Cc3cnc4cc(cnn34)C#CC(C)(C)N)ccc2O1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542791
PNG
((S)-6-(difluoromethyl)-3-((8-methoxy-2-(6-methoxyp...)
Show SMILES COc1ccc(cn1)[C@H]1COc2cc(Cn3cnc4cc(cnc34)C(F)F)cc(OC)c2O1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542813
PNG
(3-((8-methoxy-2-(6-methoxypyridin-3-yl)-2,3- dihyd...)
Show SMILES COC1CN(C1)c1cnc2c(Cc3cc(OC)c4OC(COc4c3)c3ccc(OC)nc3)cnn2c1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542518
PNG
((S)-4-(3-((2-(4-methoxyphenyl)-2,3- imidazo[4,5-b]...)
Show SMILES COc1ccc(cc1)[C@@H]1COc2cc(Cn3cnc4cc(cnc34)C#CC(C)(C)N)ccc2O1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542519
PNG
((R)-4-(3-((2-(4-methoxyphenyl)-2,3- imidazo[4,5-b]...)
Show SMILES COc1ccc(cc1)[C@H]1COc2cc(Cn3cnc4cc(cnc34)C#CC(C)(C)N)ccc2O1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542753
PNG
(3-((8-methoxy-2-(6-methoxypyridin-3-yl)-2,3- dihyd...)
Show SMILES COc1ccc(cn1)C1COc2cc(Cn3cnc4cc(cnc34)-c3cnn(C)c3)cc(OC)c2O1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542777
PNG
(6-(1,3-dimethyl-1H-pyrazol-4-yl)-3-((8-methoxy-2-(...)
Show SMILES COc1ccc(cn1)C1COc2cc(Cn3cnc4cc(cnc34)-c3cn(C)nc3C)cc(OC)c2O1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542816
PNG
(3-((8-methoxy-2-(6-methoxypyridin-3-yl)-2,3- dihyd...)
Show SMILES COc1ccc(cn1)C1COc2cc(Cc3cnn4cc(OC5CN(C)C5)cnc34)cc(OC)c2O1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542820
PNG
(3-((8-methoxy-2-(6-methoxypyridin-3-yl)-2,3- dihyd...)
Show SMILES COC1CN(C1)c1cnn2c(Cc3cc(OC)c4OC(COc4c3)c3ccc(OC)nc3)cnc2c1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542848
PNG
(3-((2-(6-ethylpyridin-3-yl)-8-methoxy-2,3- dihydro...)
Show SMILES CCc1ccc(cn1)C1COc2cc(Cc3cnn4cc(cnc34)N3CC(C3)OC)cc(OC)c2O1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542974
PNG
(3-(3-methoxy-4-((6-methoxypyridin-3-yl)methoxy)ben...)
Show SMILES COc1ccc(COc2ccc(Cn3cnc4cc(cnc34)C#CC3CCCNC3)cc2OC)cn1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542516
PNG
(4-(1-((2-(4-methoxyphenyl)-2,3- dihydrobenzo[b][1,...)
Show SMILES COc1ccc(cc1)C1COc2cc(Cn3cnc4cc(ccc34)C#CC(C)(C)N)ccc2O1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542759
PNG
(4-(3-((8-methoxy-2-(6-methoxypyridin-3-yl)-2,3- di...)
Show SMILES COc1ccc(cn1)C1COc2cc(Cn3cnc4cc(cnc34)-c3cnoc3)cc(OC)c2O1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542811
PNG
(6-bromo-3-((8-methoxy-2-(6-methoxypyridin-3-yl)-2,...)
Show SMILES COc1ccc(cn1)C1COc2cc(Cc3cnn4cc(Br)cnc34)cc(OC)c2O1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542851
PNG
(4-(3-((8-methoxy-2-(4-methoxyphenyl)-2,3- dihydrob...)
Show SMILES COc1ccc(cc1)C1COc2cc(Cn3cnc4cc(cnc34)C#CC(C)(C)N)cc(OC)c2O1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542517
PNG
(4-(3-((2-(4-methoxyphenyl)-2,3- dihydrobenzo[b][1,...)
Show SMILES COc1ccc(cc1)C1COc2cc(Cn3cnc4cc(cnc34)C#CC(C)(C)N)ccc2O1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542553
PNG
((S)-4-(3-((2-(6-methoxypyridin-3-yl)-2,3- b]pyridi...)
Show SMILES COc1ccc(cn1)[C@@H]1COc2cc(Cn3cnc4cc(cnc34)C#CC(C)(C)N)ccc2O1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542688
PNG
(4-(3-((2-(4-methoxyphenyl)-3-methyl-2,3- dihydrobe...)
Show SMILES COc1ccc(cc1)C1Oc2ccc(Cn3cnc4cc(cnc34)C#CC(C)(C)N)cc2OC1C
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542727
PNG
(4-(3-((8-fluoro-2-(4-(trifluoromethyl)phenyl)-2,3-...)
Show SMILES CC(C)(N)C#Cc1cnc2n(Cc3cc(F)c4OC(COc4c3)c3ccc(cc3)C(F)(F)F)cnc2c1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542855
PNG
(4-(3-((2-(4-(difluoromethoxy)phenyl)-8-methoxy-2,3...)
Show SMILES COc1cc(Cn2cnc3cc(cnc23)C#CC(C)(C)N)cc2OCC(Oc12)c1ccc(OC(F)F)cc1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542879
PNG
(3-((2-(6-ethoxypyridin-3-yl)-8-methoxy-2,3- dihydr...)
Show SMILES CCOc1ccc(cn1)C1COc2cc(Cn3cnc4cc(OC)cnc34)cc(OC)c2O1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542944
PNG
(7-((8-methoxy-2-(6-methoxypyridin-3-yl)-2,3- dihyd...)
Show SMILES COc1ccc(cn1)C1COc2cc(Cc3c[nH]c4nccnc34)cc(OC)c2O1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542761
PNG
((S)-6-methoxy-3-((8-methoxy-2-(6-methoxypyridin-3-...)
Show SMILES COc1cnc2n(Cc3cc(OC)c4O[C@@H](COc4c3)c3ccc(OC)nc3)cnc2c1 |r|
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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542770
PNG
(3-((8-methoxy-2-(6-methoxypyridin-3-yl)-2,3- dihyd...)
Show SMILES COc1ccc(cn1)C1COc2cc(Cn3cnc4cc(cnc34)-n3cccn3)cc(OC)c2O1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542771
PNG
(6-(1H-imidazol-1-yl)-3-((8-methoxy-2-(6-methoxypyr...)
Show SMILES COc1ccc(cn1)C1COc2cc(Cn3cnc4cc(cnc34)-n3ccnc3)cc(OC)c2O1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542831
PNG
(3-((2-(6-cyclopropylpyridin-3-yl)-8-methoxy-2,3- d...)
Show SMILES COc1cc(Cn2cnc3cc(OC4CN(C)C4)cnc23)cc2OCC(Oc12)c1ccc(nc1)C1CC1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542852
PNG
(3-((8-methoxy-2-(4-methoxyphenyl)-2,3- dihydrobenz...)
Show SMILES COc1ccc(cc1)C1COc2cc(Cn3cnc4cc(cnc34)-c3cn(C)cn3)cc(OC)c2O1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542754
PNG
(4-(3-((8-methoxy-2-(6-methoxypyridin-3-yl)-2,3- di...)
Show SMILES COc1ccc(cn1)C1COc2cc(Cn3cnc4cc(cnc34)N3CCOCC3)cc(OC)c2O1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542778
PNG
(6-(6-fluoropyridin-3-yl)-3-((8-methoxy-2-(6- metho...)
Show SMILES COc1ccc(cn1)C1COc2cc(Cn3cnc4cc(cnc34)-c3ccc(F)nc3)cc(OC)c2O1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542841
PNG
(3-((8-methoxy-2-(6-methylpyridin-3-yl)-2,3- dihydr...)
Show SMILES COC1CN(C1)c1cnn2c(Cc3cc(OC)c4OC(COc4c3)c3ccc(C)nc3)cnc2c1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542750
PNG
(4-(3-((8-methoxy-2-(6-methoxypyridin-3-yl)-2,3- di...)
Show SMILES COc1ccc(cn1)C1COc2cc(Cn3cnc4cc(cnc34)C#CC(C)(C)N)cc(OC)c2O1
PDB

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n/an/a 10n/an/an/an/an/an/a


TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542860
PNG
(3-((2-(4-(difluoromethoxy)phenyl)-8-methoxy-2,3- d...)
Show SMILES COc1cc(Cc2cnc3cccnn23)cc2OCC(Oc12)c1ccc(OC(F)F)cc1
PDB

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n/an/a 10n/an/an/an/an/an/a


TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542751
PNG
((S)-4-(3-((8-methoxy-2-(6-methoxypyridin-3-yl)-2,3...)
Show SMILES COc1ccc(cn1)[C@H]1COc2cc(Cn3cnc4cc(cnc34)C#CC(C)(C)N)cc(OC)c2O1 |r|
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542786
PNG
((S)-azetidin-1-yl(3-((8-methoxy-2-(6-methoxypyridi...)
Show SMILES COc1ccc(cn1)[C@@H]1COc2cc(Cn3cnc4cc(cnc34)C(=O)N3CCC3)cc(OC)c2O1 |r|
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542825
PNG
(3-((2-(6-cyclopropylpyridin-3-yl)-8-methoxy-2,3- d...)
Show SMILES COc1cc(Cn2cnc3cccnc23)cc2OCC(Oc12)c1ccc(nc1)C1CC1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542827
PNG
(3-((2-(6-cyclopropylpyridin-3-yl)-8-methoxy-2,3- d...)
Show SMILES COc1cc(Cn2cnc3ccc(C)nc23)cc2OCC(Oc12)c1ccc(nc1)C1CC1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542846
PNG
(3-((2-(6-ethylpyridin-3-yl)-8-methoxy-2,3- dihydro...)
Show SMILES CCc1ccc(cn1)C1COc2cc(Cn3cnc4cc(OC)cnc34)cc(OC)c2O1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542737
PNG
(4-(3-((8-fluoro-2-(6-methoxypyridin-3-yl)-2,3- dih...)
Show SMILES COc1ccc(cn1)C1COc2cc(Cn3cnc4cc(cnc34)C#CC(C)(C)N)cc(F)c2O1
PDB

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n/an/a 12n/an/an/an/an/an/a


TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542738
PNG
(3-((8-fluoro-2-(6-methoxypyridin-3-yl)-2,3- dihydr...)
Show SMILES COc1ccc(cn1)C1COc2cc(Cn3cnc4cc(cnc34)C#CC3CCCNC3)cc(F)c2O1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM542760
PNG
(6-methoxy-3-((8-methoxy-2-(6-methoxypyridin-3-yl)-...)
Show SMILES COc1cnc2n(Cc3cc(OC)c4OC(COc4c3)c3ccc(OC)nc3)cnc2c1
PDB

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TBA

Assay Description
All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QC06QT
More data for this
Ligand-Target Pair
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