Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclin-dependent kinase 4 (Homo sapiens (Human)) | BDBM448940![]() (N-(5-(4-Ethylpiperazin-1-yl)pyridin-2-yl)-5-fluoro...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 4 (Homo sapiens (Human)) | BDBM448950![]() (N-(5-(1-Ethylpiperidine-4-yl)pyridin-2-yl)-5-fluor...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 4 (Homo sapiens (Human)) | BDBM556330![]() (N-(5-((1-ethylpiperidin-4-yl)methoxy)pyridin-2-yl)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 4 (Homo sapiens (Human)) | BDBM556335![]() (5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihydro-1H-b...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 4 (Homo sapiens (Human)) | BDBM556334![]() (3-(4-((6-(5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-di...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 4 (Homo sapiens (Human)) | BDBM448926![]() (1-(2-((5-Fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihyd...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 4 (Homo sapiens (Human)) | BDBM50455050![]() (CHEMBL4208172 | US10696678, Example 18 | US1135117...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.140 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 4 (Homo sapiens (Human)) | BDBM556329![]() (N-(5-((1-ethylpiperidin-4-yl)methoxy)pyridin-2-yl)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 4 (Homo sapiens (Human)) | BDBM448950![]() (N-(5-(1-Ethylpiperidine-4-yl)pyridin-2-yl)-5-fluor...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.170 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 4 (Homo sapiens (Human)) | BDBM556328![]() ((S)N-(5-(3-(dimethylamino)pyrrolidin-1-yl)py...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.180 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 4 (Homo sapiens (Human)) | BDBM556327![]() ((S)-(3-(dimethylamino)pyrrolidin-1-yl)(6-(5-fluoro...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 4 (Homo sapiens (Human)) | BDBM556336![]() (5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihydro-1H-b...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.25 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 4 (Homo sapiens (Human)) | BDBM556337![]() (2-(4-(6-(5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dih...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.25 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 4 (Homo sapiens (Human)) | BDBM556331![]() (5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihydro-1H-b...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.260 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 4 (Homo sapiens (Human)) | BDBM50110183![]() (Abemaciclib | LY-2835219 | US10626107, Example LY2...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem Similars | PDB US Patent | n/a | n/a | 0.260 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Cyclin-dependent kinase 4 (Homo sapiens (Human)) | BDBM50110183![]() (Abemaciclib | LY-2835219 | US10626107, Example LY2...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem Similars | PDB US Patent | n/a | n/a | 0.260 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Cyclin-dependent kinase 4 (Homo sapiens (Human)) | BDBM556326![]() (1-(4-((6-(5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-di...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.730 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 6 (Homo sapiens (Human)) | BDBM448940![]() (N-(5-(4-Ethylpiperazin-1-yl)pyridin-2-yl)-5-fluoro...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.880 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 6 (Homo sapiens (Human)) | BDBM556334![]() (3-(4-((6-(5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-di...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.02 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 6 (Homo sapiens (Human)) | BDBM556327![]() ((S)-(3-(dimethylamino)pyrrolidin-1-yl)(6-(5-fluoro...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.19 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 6 (Homo sapiens (Human)) | BDBM448926![]() (1-(2-((5-Fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihyd...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.87 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 6 (Homo sapiens (Human)) | BDBM556335![]() (5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihydro-1H-b...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.89 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 6 (Homo sapiens (Human)) | BDBM448950![]() (N-(5-(1-Ethylpiperidine-4-yl)pyridin-2-yl)-5-fluor...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.93 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 6 (Homo sapiens (Human)) | BDBM448950![]() (N-(5-(1-Ethylpiperidine-4-yl)pyridin-2-yl)-5-fluor...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.42 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 6 (Homo sapiens (Human)) | BDBM556331![]() (5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihydro-1H-b...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.46 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 6 (Homo sapiens (Human)) | BDBM50455050![]() (CHEMBL4208172 | US10696678, Example 18 | US1135117...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.71 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 6 (Homo sapiens (Human)) | BDBM556337![]() (2-(4-(6-(5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dih...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.72 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 6 (Homo sapiens (Human)) | BDBM556330![]() (N-(5-((1-ethylpiperidin-4-yl)methoxy)pyridin-2-yl)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 6 (Homo sapiens (Human)) | BDBM50110183![]() (Abemaciclib | LY-2835219 | US10626107, Example LY2...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem Similars | PDB US Patent | n/a | n/a | 3.41 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Cyclin-dependent kinase 6 (Homo sapiens (Human)) | BDBM50110183![]() (Abemaciclib | LY-2835219 | US10626107, Example LY2...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem Similars | PDB US Patent | n/a | n/a | 3.41 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Cyclin-dependent kinase 6 (Homo sapiens (Human)) | BDBM556336![]() (5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihydro-1H-b...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.92 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 6 (Homo sapiens (Human)) | BDBM556328![]() ((S)N-(5-(3-(dimethylamino)pyrrolidin-1-yl)py...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.96 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 6 (Homo sapiens (Human)) | BDBM556329![]() (N-(5-((1-ethylpiperidin-4-yl)methoxy)pyridin-2-yl)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.72 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 6 (Homo sapiens (Human)) | BDBM556326![]() (1-(4-((6-(5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-di...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.84 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 4 (Homo sapiens (Human)) | BDBM556338![]() (N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 9.46 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 5 (Homo sapiens (Human)) | BDBM556330![]() (N-(5-((1-ethylpiperidin-4-yl)methoxy)pyridin-2-yl)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 11.3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM448926![]() (1-(2-((5-Fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihyd...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 17.6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 5 (Homo sapiens (Human)) | BDBM556327![]() ((S)-(3-(dimethylamino)pyrrolidin-1-yl)(6-(5-fluoro...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 19.1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM556327![]() ((S)-(3-(dimethylamino)pyrrolidin-1-yl)(6-(5-fluoro...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 20.4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM556330![]() (N-(5-((1-ethylpiperidin-4-yl)methoxy)pyridin-2-yl)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 24.7 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 5 (Homo sapiens (Human)) | BDBM448926![]() (1-(2-((5-Fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihyd...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 36.8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 5 (Homo sapiens (Human)) | BDBM448950![]() (N-(5-(1-Ethylpiperidine-4-yl)pyridin-2-yl)-5-fluor...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 38.3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM556334![]() (3-(4-((6-(5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-di...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 44.9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 5 (Homo sapiens (Human)) | BDBM448940![]() (N-(5-(4-Ethylpiperazin-1-yl)pyridin-2-yl)-5-fluoro...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 46.8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 5 (Homo sapiens (Human)) | BDBM556328![]() ((S)N-(5-(3-(dimethylamino)pyrrolidin-1-yl)py...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 50.6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM50455050![]() (CHEMBL4208172 | US10696678, Example 18 | US1135117...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 51.1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM556335![]() (5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihydro-1H-b...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 55.2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM556331![]() (5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihydro-1H-b...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 64.1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM556328![]() ((S)N-(5-(3-(dimethylamino)pyrrolidin-1-yl)py...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 65.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM556337![]() (2-(4-(6-(5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dih...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 70.3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1PTP | |||||||||||
More data for this Ligand-Target Pair |
Displayed 1 to 50 (of 72 total ) | Next | Last >> |