Compile Data Set for Download or QSAR

Found 216 hits Enz. Inhib. hit(s) with all data for entry = 10711   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoglyceride lipase (Homo sapiens (Human))	BDBM561384 (US11390610, Example 213) Show SMILES CCC1(CC)CCN(C1)c1ccc(cc1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561025 (US11390610, Example 67) Show SMILES CC(C)(C)Cc1nc(no1)-c1ccc(cc1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561355 (US11390610, Example 184) Show SMILES Clc1cccc(OCc2ccc(cc2Cl)C(=O)N2CCN(CC2)c2nc3ccccc3c(=O)[nH]2)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561217 (US11390610, Example 116) Show SMILES Clc1ccc(cc1Cl)-c1nc2ccc(cc2o1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561381 (US11390610, Example 210) Show SMILES O=C(N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1)c1ccc2nc(oc2c1)N1CCC2(CCC2)C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561367 (US11390610, Example 196) Show SMILES CC(C)(C)c1nc(no1)-c1ccc(cc1)C(=O)N1CCN(CC1)c1nc2ccc(Cl)cc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561341 (US11390610, Example 170) Show SMILES O=C(N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1)c1ccc(cc1)N1CCC2(CCC2)C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561328 (US11390610, Example 157) Show SMILES O=C(N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1)c1ccc2nc(oc2c1)N1CC2(C1)CCCC2 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561382 (US11390610, Example 211) Show SMILES CC(C)(COCc1ccccc1)c1nc(no1)-c1ccc(cc1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561368 (US11390610, Example 197) Show SMILES CC1(C)CCN(C1)c1ccc(cc1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561363 (US11390610, Example 192) Show SMILES Clc1cc(ccc1C#N)-c1nc2ccc(cc2o1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561375 (US11390610, Example 204) Show SMILES O=C(N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1)c1ccc2nc(oc2c1)N1CC2(CCC2)C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561038 (US11390610, Example 75) Show SMILES CC(C)(C)c1nc(no1)-c1ccc(cc1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561019 (US11390610, Example 61) Show SMILES Clc1cccc(c1)-c1nc2ccc(cc2o1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561299 (US11390610, Example 128) Show SMILES O=C(N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1)c1ccc(cc1)N1CC2(C1)CCCC2 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561046 (US11390610, Example 83) Show SMILES FC(F)(F)Oc1cccc(c1)-c1ccc(cc1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM560942 (US11390610, Example 1 | US11390610, Example 160) Show SMILES CC(=O)N(CCc1ccc(cc1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1)Cc1cccc(c1)C(F)(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561034 (US11390610, Example 73) Show SMILES Cc1cc(ccc1OCc1cccc(Cl)c1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561068 (US11390610, Example 96) Show SMILES Fc1cc(ccc1-c1cccc(c1)C(F)(F)F)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561373 (US11390610, Example 202) Show SMILES FC1(F)CC2(CN(C2)c2nc3ccc(cc3o2)C(=O)N2CCN(CC2)c2nc3ccccc3c(=O)[nH]2)C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561362 (US11390610, Example 191) Show SMILES CC(C)(CF)c1nc(no1)-c1ccc(cc1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561020 (US11390610, Example 62) Show SMILES FC(F)(F)c1cccc(c1)-c1nc2ccc(cc2o1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561364 (US11390610, Example 193) Show SMILES CC(C)(C)c1noc(n1)-c1ccc(cc1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561099 (US11390610, Example 112) Show SMILES CC1(C)CCN(CC1)c1ccc(cc1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561024 (US11390610, Example 66) Show SMILES Clc1cccc(COc2ccc(cc2Cl)C(=O)N2CCN(CC2)c2nc3ccccc3c(=O)[nH]2)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561327 (US11390610, Example 156) Show SMILES O=C(N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1)c1cc(N2CCOCC2)c2nc(oc2c1)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561033 (US11390610, Example 72) Show SMILES FC(F)(F)c1cc(ccc1OCc1cccc(Cl)c1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561039 (US11390610, Example 76) Show SMILES Clc1cccc(COc2ccc(cc2-c2ncc[nH]2)C(=O)N2CCN(CC2)c2nc3ccccc3c(=O)[nH]2)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561366 (2-[4-[3-(3-Chlorophenyl)sulfonyl-3,9-diazaspiro[5....) Show SMILES Clc1cccc(c1)S(=O)(=O)N1CCC2(CCN(CC2)C(=O)N2CCN(CC2)c2nc3ccccc3c(=O)[nH]2)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM560969 (US11390610, Example 17) Show SMILES FC(F)(F)c1cccc(c1)-c1ccc(cc1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561302 (US11390610, Example 131) Show SMILES Fc1ccc(cc1F)-c1nc2ccc(cc2o1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM560956 (US11390610, Example 12) Show SMILES Ic1ccccc1CNc1ccc(cc1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561329 (US11390610, Example 158) Show SMILES FC1(F)CCC11CN(C1)c1nc2ccc(cc2o1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561088 (US11390610, Example 104) Show SMILES O=C(N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1)c1ccc(cc1)-c1cccc(OCc2ccccc2)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561090 (US11390610, Example 106) Show SMILES COc1ccc(cc1C(F)(F)F)-c1ccc(cc1C)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561321 (US11390610, Example 150) Show SMILES Fc1cc(ccc1-c1cccc(OC(F)(F)F)c1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561218 (US11390610, Example 117) Show SMILES Clc1ccc(cc1)-c1nc2ccc(cc2o1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561029 (US11390610, Example 69) Show SMILES O=C(N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1)c1ccc(cc1)N1CCc2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561011 (US11390610, Example 54) Show SMILES O=C(N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1)c1ccc2nc(oc2c1)N1CCCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561345 (US11390610, Example 174) Show SMILES O=C(N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1)c1ccc(cc1)N1CCC2(CC2)C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561229 (US11390610, Example 119) Show SMILES O=C(N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1)c1ccc(cc1)N1CC2(CCC2)C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561346 (2-[4-[3-Chloro-4-[(4-chloropyridin-2-yl)methoxy]be...) Show SMILES Clc1ccnc(COc2ccc(cc2Cl)C(=O)N2CCN(CC2)c2nc3ccccc3c(=O)[nH]2)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM560942 (US11390610, Example 1 | US11390610, Example 160) Show SMILES CC(=O)N(CCc1ccc(cc1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1)Cc1cccc(c1)C(F)(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM560954 (US11390610, Example 10) Show SMILES Fc1ccc(cc1)-n1ccc2cc(ccc12)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561306 (US11390610, Example 135) Show SMILES Fc1ccc2nc([nH]c(=O)c2c1)N1CCN(CC1)C(=O)c1ccc2nc(oc2c1)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM560943 (US11390610, Example 2) Show SMILES Fc1cccc(\C=C\c2ccc(cc2)C(=O)N2CCN(CC2)c2nc3ccccc3c(=O)[nH]2)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561298 (US11390610, Example 127) Show SMILES CC(C)(C)Cc1nc(no1)-c1cccc(c1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561005 (US11390610, Example 48) Show SMILES Fc1cccc(c1)-c1cc2cc(ccc2[nH]1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561340 (US11390610, Example 169) Show SMILES CC1CCN(C1)c1nc2ccc(cc2o1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561356 (US11390610, Example 185) Show SMILES O=C(N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1)c1ccc2nc(sc2c1)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 216 total )  |  Next  |  Last  >>

Jump to: