Compile Data Set for Download or QSAR

Found 368 hits Enz. Inhib. hit(s) with all data for entry = 10802   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261105 (5-{1-[4-amino-3-(difluoromethyl)-1H-pyrazolo[3,4-d...) Show SMILES COc1c(cc(C#N)c(C)c1C1CN(C1)C(C)C)C(C)n1nc(C(F)F)c2c(N)ncnc12 Show InChI InChI=1S/C23H27F2N7O/c1-11(2)31-8-15(9-31)17-12(3)14(7-26)6-16(20(17)33-5)13(4)32-23-18(19(30-32)21(24)25)22(27)28-10-29-23/h6,10-11,13,15,21H,8-9H2,1-5H3,(H2,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261106 (5-{1-[4-Amino-3-(difluoromethyl)-1H-pyrazolo[3,4-d...) Show SMILES COc1c(cc(C#N)c(C)c1C1CN(CC(F)(F)F)C1)C(C)n1nc(C(F)F)c2c(N)ncnc12 Show InChI InChI=1S/C22H22F5N7O/c1-10-12(5-28)4-14(18(35-3)15(10)13-6-33(7-13)8-22(25,26)27)11(2)34-21-16(17(32-34)19(23)24)20(29)30-9-31-21/h4,9,11,13,19H,6-8H2,1-3H3,(H2,29,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261107 (5-{1-[4-Amino-3-(difluoromethyl)-1H-pyrazolo[3,4-d...) Show SMILES COc1c(cc(C#N)c(C)c1C1CN(CCO)C1)C(C)n1nc(C(F)F)c2c(N)ncnc12 Show InChI InChI=1S/C22H25F2N7O2/c1-11-13(7-25)6-15(19(33-3)16(11)14-8-30(9-14)4-5-32)12(2)31-22-17(18(29-31)20(23)24)21(26)27-10-28-22/h6,10,12,14,20,32H,4-5,8-9H2,1-3H3,(H2,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261108 (5-{1-[4-Amino-3-(difluoromethyl)-1H-pyrazolo[3,4-d...) Show SMILES COc1c(cc(C#N)c(C)c1C1CN(C[C@H](C)O)C1)C(C)n1nc(C(F)F)c2c(N)ncnc12 |r| Show InChI InChI=1S/C23H27F2N7O2/c1-11(33)7-31-8-15(9-31)17-12(2)14(6-26)5-16(20(17)34-4)13(3)32-23-18(19(30-32)21(24)25)22(27)28-10-29-23/h5,10-11,13,15,21,33H,7-9H2,1-4H3,(H2,27,28,29)/t11-,13?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261109 (US10092570, Example 132 | US10376513, Example 132 ...) Show SMILES COc1c(cc(C#N)c(C)c1C1CN(C[C@@H](C)O)C1)C(C)n1nc(C(F)F)c2c(N)ncnc12 |r| Show InChI InChI=1S/C23H27F2N7O2/c1-11(33)7-31-8-15(9-31)17-12(2)14(6-26)5-16(20(17)34-4)13(3)32-23-18(19(30-32)21(24)25)22(27)28-10-29-23/h5,10-11,13,15,21,33H,7-9H2,1-4H3,(H2,27,28,29)/t11-,13?/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261110 (5-{-1-[4-Amino-3-(difluoromethyl)-1H-pyrazolo[3,4-...) Show SMILES COc1c(cc(C#N)c(C)c1C1CN(CC(C)(C)O)C1)C(C)n1nc(C(F)F)c2c(N)ncnc12 Show InChI InChI=1S/C24H29F2N7O2/c1-12-14(7-27)6-16(20(35-5)17(12)15-8-32(9-15)10-24(3,4)34)13(2)33-23-18(19(31-33)21(25)26)22(28)29-11-30-23/h6,11,13,15,21,34H,8-10H2,1-5H3,(H2,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261111 ((2S)-2-[3-(3-{1-[4-Amino-3-(difluoromethyl)-1H-pyr...) Show SMILES CNC(=O)[C@H](C)N1CC(C1)c1c(C)c(cc(C(C)n2nc(C(F)F)c3c(N)ncnc23)c1OC)C#N |r| Show InChI InChI=1S/C24H28F2N8O2/c1-11-14(7-27)6-16(20(36-5)17(11)15-8-33(9-15)13(3)24(35)29-4)12(2)34-23-18(19(32-34)21(25)26)22(28)30-10-31-23/h6,10,12-13,15,21H,8-9H2,1-5H3,(H,29,35)(H2,28,30,31)/t12?,13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261112 (US10092570, Example 135 | US10376513, Example 135 ...) Show SMILES CNC(=O)[C@@H](C)N1CC(C1)c1c(C)c(cc(C(C)n2nc(C(F)F)c3c(N)ncnc23)c1OC)C#N |r| Show InChI InChI=1S/C24H28F2N8O2/c1-11-14(7-27)6-16(20(36-5)17(11)15-8-33(9-15)13(3)24(35)29-4)12(2)34-23-18(19(32-34)21(25)26)22(28)30-10-31-23/h6,10,12-13,15,21H,8-9H2,1-5H3,(H,29,35)(H2,28,30,31)/t12?,13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261113 (5-{1-[4-Amino-3-(difluoromethyl)-1H-pyrazolo[3,4-d...) Show SMILES COc1c(cc(C#N)c(C)c1C1CN(CC(F)F)C1)C(C)n1nc(C(F)F)c2c(N)ncnc12 Show InChI InChI=1S/C22H23F4N7O/c1-10-12(5-27)4-14(19(34-3)16(10)13-6-32(7-13)8-15(23)24)11(2)33-22-17(18(31-33)20(25)26)21(28)29-9-30-22/h4,9,11,13,15,20H,6-8H2,1-3H3,(H2,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261108 (5-{1-[4-Amino-3-(difluoromethyl)-1H-pyrazolo[3,4-d...) Show SMILES COc1c(cc(C#N)c(C)c1C1CN(C[C@H](C)O)C1)C(C)n1nc(C(F)F)c2c(N)ncnc12 |r| Show InChI InChI=1S/C23H27F2N7O2/c1-11(33)7-31-8-15(9-31)17-12(2)14(6-26)5-16(20(17)34-4)13(3)32-23-18(19(30-32)21(24)25)22(27)28-10-29-23/h5,10-11,13,15,21,33H,7-9H2,1-4H3,(H2,27,28,29)/t11-,13?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261115 (3-(1-Acetylazetidin-3-yl)-5-{1-[4-amino-3-(difluor...) Show SMILES COc1c(cc(C#N)c(C)c1C1CN(C1)C(C)=O)C(C)n1nc(C(F)F)c2c(N)ncnc12 Show InChI InChI=1S/C22H23F2N7O2/c1-10-13(6-25)5-15(19(33-4)16(10)14-7-30(8-14)12(3)32)11(2)31-22-17(18(29-31)20(23)24)21(26)27-9-28-22/h5,9,11,14,20H,7-8H2,1-4H3,(H2,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM289138 (US10092570, Example 139 | US10376513, Example 139 ...) Show SMILES CCOc1c(cc(Cl)c(F)c1C1CN(C1)C(C)C)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C22H28ClFN6O/c1-6-31-20-15(7-16(23)19(24)18(20)14-8-29(9-14)11(2)3)13(5)30-22-17(12(4)28-30)21(25)26-10-27-22/h7,10-11,13-14H,6,8-9H2,1-5H3,(H2,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261117 (1-(3-{3-[1-(4-Amino-3-methyl-1H-pyrazolo[3,4-d]pyr...) Show SMILES CCOc1c(cc(Cl)c(F)c1C1CN(CC(C)(C)O)C1)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C23H30ClFN6O2/c1-6-33-20-15(13(3)31-22-17(12(2)29-31)21(26)27-11-28-22)7-16(24)19(25)18(20)14-8-30(9-14)10-23(4,5)32/h7,11,13-14,32H,6,8-10H2,1-5H3,(H2,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261118 (1-(1-{5-Chloro-2-ethoxy-4-fluoro-3-[1-(2,2,2-trifl...) Show SMILES CCOc1c(cc(Cl)c(F)c1C1CN(CC(F)(F)F)C1)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C21H23ClF4N6O/c1-4-33-18-13(11(3)32-20-15(10(2)30-32)19(27)28-9-29-20)5-14(22)17(23)16(18)12-6-31(7-12)8-21(24,25)26/h5,9,11-12H,4,6-8H2,1-3H3,(H2,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM570492 ((2R)-1-(3-{3-[1-(4-Amino-3- methyl-1H-pyrazolo[3,4...) Show SMILES CCOc1c(cc(Cl)c(F)c1C1CN(C[C@H](O)F)C1)C(C)n1nc(C)c2c(N)ncnc12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM570493 ((2S)-1-(3-{3-[1-(4-Amino-3- methyl-1H-pyrazolo[3,4...) Show SMILES CCOc1c(cc(Cl)c(F)c1C1CN(C[C@@H](O)F)C1)C(C)n1nc(C)c2c(N)ncnc12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261121 (2-(3-{3-[1-(4-Amino-3-methyl-1H- pyrazolo[3,4-d]py...) Show SMILES CCOc1c(cc(Cl)c(F)c1C1CN(CCO)C1)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C21H26ClFN6O2/c1-4-31-19-14(7-15(22)18(23)17(19)13-8-28(9-13)5-6-30)12(3)29-21-16(11(2)27-29)20(24)25-10-26-21/h7,10,12-13,30H,4-6,8-9H2,1-3H3,(H2,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261122 (1-{1-[5-Chloro-2-ethoxy-4-fluoro- 3-(1-methylazeti...) Show SMILES CCOc1c(cc(Cl)c(F)c1C1CN(C)C1)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C20H24ClFN6O/c1-5-29-18-13(6-14(21)17(22)16(18)12-7-27(4)8-12)11(3)28-20-15(10(2)26-28)19(23)24-9-25-20/h6,9,11-12H,5,7-8H2,1-4H3,(H2,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261123 (1-{1-[5-Chloro-2-ethoxy-3-(1- ethylazetidin-3-yl)-...) Show SMILES CCOc1c(cc(Cl)c(F)c1C1CN(CC)C1)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C21H26ClFN6O/c1-5-28-8-13(9-28)17-18(23)15(22)7-14(19(17)30-6-2)12(4)29-21-16(11(3)27-29)20(24)25-10-26-21/h7,10,12-13H,5-6,8-9H2,1-4H3,(H2,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261124 (1-(1-{5-Chloro-3-[1-(2,2- difluoroethyl)azetidin-3...) Show SMILES CCOc1c(cc(Cl)c(F)c1C1CN(CC(F)F)C1)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C21H24ClF3N6O/c1-4-32-19-13(11(3)31-21-16(10(2)29-31)20(26)27-9-28-21)5-14(22)18(25)17(19)12-6-30(7-12)8-15(23)24/h5,9,11-12,15H,4,6-8H2,1-3H3,(H2,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261125 (2-(3-{3-[1-(4-Amino-3-methyl-1H- pyrazolo[3,4-d]py...) Show SMILES CCOc1c(cc(Cl)c(F)c1C1CN(CC(N)=O)C1)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C21H25ClFN7O2/c1-4-32-19-13(11(3)30-21-16(10(2)28-30)20(25)26-9-27-21)5-14(22)18(23)17(19)12-6-29(7-12)8-15(24)31/h5,9,11-12H,4,6-8H2,1-3H3,(H2,24,31)(H2,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261120 ((2S)-1-(3-{3-[1-(4-Amino-3- methyl-1H-pyrazolo[3,4...) Show SMILES CCOc1c(cc(Cl)c(F)c1C1CN(C[C@H](C)O)C1)C(C)n1nc(C)c2c(N)ncnc12 |r| Show InChI InChI=1S/C22H28ClFN6O2/c1-5-32-20-15(13(4)30-22-17(12(3)28-30)21(25)26-10-27-22)6-16(23)19(24)18(20)14-8-29(9-14)7-11(2)31/h6,10-11,13-14,31H,5,7-9H2,1-4H3,(H2,25,26,27)/t11-,13?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM570500 (US11433071, Example 150) Show SMILES CCOc1c(cc(Cl)c(F)c1C1CN(C1)C(C)C)[C@@H](C)n1nc(C(F)F)c2c(N)ncnc12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261128 (US10092570, Example 151 | US10376513, Example 151 ...) Show SMILES CCOc1c(cc(Cl)c(F)c1C1CN(C)C1)C(C)n1nc(C(F)F)c2c(N)ncnc12 Show InChI InChI=1S/C20H22ClF3N6O/c1-4-31-17-11(5-12(21)15(22)13(17)10-6-29(3)7-10)9(2)30-20-14(16(28-30)18(23)24)19(25)26-8-27-20/h5,8-10,18H,4,6-7H2,1-3H3,(H2,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM570502 (2-[3-(3-{1-[4-Amino-3-(difluoromethyl)-1H-pyrazolo...) Show SMILES CCOc1c(cc(Cl)c(F)c1C1CN(CCO)C1)[C@@H](C)n1nc(C(F)F)c2c(N)ncnc12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM570503 (1-[3-(3-{1-[4-Amino-3-(difluoromethyl)- 1H-pyrazol...) Show SMILES CCOc1c(cc(Cl)c(F)c1C1CN(CC(C)(C)O)C1)[C@H](C)n1nc(C(F)F)c2c(N)ncnc12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM570504 ((2S)-1-[3-(3-{1-[4-Amino-3- (difluoromethyl)-1H-py...) Show SMILES CCOc1c(cc(Cl)c(F)c1C1CN(C[C@H](C)O)C1)[C@H](C)n1nc(C(F)F)c2c(N)ncnc12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM570505 (US11433071, Example 155) Show SMILES CCOc1c(cc(Cl)c(F)c1C1CN(C[C@@H](C)O)C1)[C@H](C)n1nc(C(F)F)c2c(N)ncnc12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261133 ((2R)-2-(3-{3-[1-(4-Amino-3-methyl-1H-pyrazolo[3,4-...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(C1)[C@H](C)CO)C(C)n1nc(C)c2c(N)ncnc12 |r| Show InChI InChI=1S/C22H29ClN6O2/c1-11(9-30)28-7-15(8-28)18-12(2)17(23)6-16(20(18)31-5)14(4)29-22-19(13(3)27-29)21(24)25-10-26-22/h6,10-11,14-15,30H,7-9H2,1-5H3,(H2,24,25,26)/t11-,14?/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261134 ((2S)-2-(3-{3-[1-(4-Amino-3- methyl-1H-pyrazolo[3,4...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(C1)[C@@H](C)CO)C(C)n1nc(C)c2c(N)ncnc12 |r| Show InChI InChI=1S/C22H29ClN6O2/c1-11(9-30)28-7-15(8-28)18-12(2)17(23)6-16(20(18)31-5)14(4)29-22-19(13(3)27-29)21(24)25-10-26-22/h6,10-11,14-15,30H,7-9H2,1-5H3,(H2,24,25,26)/t11-,14?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261135 (1-(3-{3-[1-(4-Amino-3-methyl-1H-pyrazolo[3,4-d]pyr...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(CC(C)(C)O)C1)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C23H31ClN6O2/c1-12-17(24)7-16(14(3)30-22-19(13(2)28-30)21(25)26-11-27-22)20(32-6)18(12)15-8-29(9-15)10-23(4,5)31/h7,11,14-15,31H,8-10H2,1-6H3,(H2,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261136 ((2R)-2-(3-{3-[1-(4-Amino-3-methyl-1H-pyrazolo[3,4-...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(C1)[C@H](C)C(=O)N(C)C)C(C)n1nc(C)c2c(N)ncnc12 |r| Show InChI InChI=1S/C24H32ClN7O2/c1-12-18(25)8-17(14(3)32-23-20(13(2)29-32)22(26)27-11-28-23)21(34-7)19(12)16-9-31(10-16)15(4)24(33)30(5)6/h8,11,14-16H,9-10H2,1-7H3,(H2,26,27,28)/t14?,15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261136 ((2R)-2-(3-{3-[1-(4-Amino-3-methyl-1H-pyrazolo[3,4-...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(C1)[C@H](C)C(=O)N(C)C)C(C)n1nc(C)c2c(N)ncnc12 |r| Show InChI InChI=1S/C24H32ClN7O2/c1-12-18(25)8-17(14(3)32-23-20(13(2)29-32)22(26)27-11-28-23)21(34-7)19(12)16-9-31(10-16)15(4)24(33)30(5)6/h8,11,14-16H,9-10H2,1-7H3,(H2,26,27,28)/t14?,15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261138 (US10092570, Example 161 | US10376513, Example 161 ...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(C1)C1(CC#N)CCC1)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C25H30ClN7O/c1-14-19(26)10-18(16(3)33-24-21(15(2)31-33)23(28)29-13-30-24)22(34-4)20(14)17-11-32(12-17)25(8-9-27)6-5-7-25/h10,13,16-17H,5-8,11-12H2,1-4H3,(H2,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM289161 (3-(3-{3-[1-(4-Amino-3-methyl- 1H-pyrazolo[3,4-d]py...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(CC(C)C#N)C1)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C23H28ClN7O/c1-12(7-25)8-30-9-16(10-30)19-13(2)18(24)6-17(21(19)32-5)15(4)31-23-20(14(3)29-31)22(26)27-11-28-23/h6,11-12,15-16H,8-10H2,1-5H3,(H2,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261140 (1-{1-[5-Chloro-2-methoxy-4-methyl-3-(1-methylpiper...) Show SMILES COc1c(cc(Cl)c(C)c1C1CCN(C)CC1)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C22H29ClN6O/c1-12-17(23)10-16(20(30-5)18(12)15-6-8-28(4)9-7-15)14(3)29-22-19(13(2)27-29)21(24)25-11-26-22/h10-11,14-15H,6-9H2,1-5H3,(H2,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261141 (1-(4-{3-[1-(4-Amino-3-methyl-1H-pyrazolo[3,4-d]pyr...) Show SMILES COc1c(cc(Cl)c(C)c1C1CCN(CC(C)(C)O)CC1)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C25H35ClN6O2/c1-14-19(26)11-18(16(3)32-24-21(15(2)30-32)23(27)28-13-29-24)22(34-6)20(14)17-7-9-31(10-8-17)12-25(4,5)33/h11,13,16-17,33H,7-10,12H2,1-6H3,(H2,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261142 (5-(3-{1-[4-Amino-3-(cyanomethyl)-1H-pyrazolo[3,4-d...) Show SMILES CCOc1c(cc(Cl)c(C)c1-c1ccc(nc1)C(=O)N(C)C)C(C)n1nc(CC#N)c2c(N)ncnc12 Show InChI InChI=1S/C26H27ClN8O2/c1-6-37-23-17(15(3)35-25-22(19(33-35)9-10-28)24(29)31-13-32-25)11-18(27)14(2)21(23)16-7-8-20(30-12-16)26(36)34(4)5/h7-8,11-13,15H,6,9H2,1-5H3,(H2,29,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261143 (3-{3-[1-(4-Amino-3-methyl-1H-pyrazolo[3,4-d]pyrimi...) Show SMILES COc1c(cc(Cl)c(C)c1C1CC(O)C1)C(C)n1nc(C)c2c(N)ncnc12 |(.77,1.41,;-.56,2.18,;-1.9,1.41,;-1.9,-.13,;-3.23,-.9,;-4.56,-.13,;-5.9,-.9,;-4.56,1.41,;-5.9,2.18,;-3.23,2.18,;-3.23,3.72,;-2.14,4.81,;-3.23,5.9,;-3.23,7.44,;-4.32,4.81,;-.56,-.9,;.77,-.13,;-.56,-2.44,;-1.81,-3.34,;-1.33,-4.81,;-2.1,-6.14,;.21,-4.81,;1.24,-5.95,;.84,-7.44,;2.74,-5.63,;3.22,-4.17,;2.19,-3.02,;.68,-3.34,)| Show InChI InChI=1S/C20H24ClN5O2/c1-9-15(21)7-14(18(28-4)16(9)12-5-13(27)6-12)11(3)26-20-17(10(2)25-26)19(22)23-8-24-20/h7-8,11-13,27H,5-6H2,1-4H3,(H2,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM255800 (5-{3-[1-(4-Amino-3-methyl-1H-pyrazolo[3,4-d]pyrimi...) Show SMILES COc1c(cc(Cl)c(C)c1-c1ccc(nc1)C(=O)N(C)C)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C24H26ClN7O2/c1-12-17(25)9-16(14(3)32-23-20(13(2)30-32)22(26)28-11-29-23)21(34-6)19(12)15-7-8-18(27-10-15)24(33)31(4)5/h7-11,14H,1-6H3,(H2,26,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261145 (1-(1-(5-chloro-2-methoxy-4- methyl-3-(pyrimidin-5-...) Show SMILES COc1c(cc(Cl)c(C)c1-c1cncnc1)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C20H20ClN7O/c1-10-15(21)5-14(18(29-4)16(10)13-6-23-8-24-7-13)12(3)28-20-17(11(2)27-28)19(22)25-9-26-20/h5-9,12H,1-4H3,(H2,22,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261146 (1-(1-(3-(2-aminopyrimidin-5-yl)-5- chloro-2-methox...) Show SMILES COc1c(cc(Cl)c(C)c1-c1cnc(N)nc1)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C20H21ClN8O/c1-9-14(21)5-13(17(30-4)15(9)12-6-24-20(23)25-7-12)11(3)29-19-16(10(2)28-29)18(22)26-8-27-19/h5-8,11H,1-4H3,(H2,22,26,27)(H2,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261147 (5-(3-(1-(4-amino-3-methyl-1H- pyrazolo[3,4-d]pyrim...) Show SMILES COc1c(cc(Cl)c(C)c1-c1cncc(c1)C#N)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C22H20ClN7O/c1-11-17(23)6-16(20(31-4)18(11)15-5-14(7-24)8-26-9-15)13(3)30-22-19(12(2)29-30)21(25)27-10-28-22/h5-6,8-10,13H,1-4H3,(H2,25,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261148 (1-(1-(3-(6-aminopyridin-3-yl)-5- chloro-2-methoxy-...) Show SMILES COc1c(cc(Cl)c(C)c1-c1ccc(N)nc1)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C21H22ClN7O/c1-10-15(22)7-14(19(30-4)17(10)13-5-6-16(23)25-8-13)12(3)29-21-18(11(2)28-29)20(24)26-9-27-21/h5-9,12H,1-4H3,(H2,23,25)(H2,24,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261149 (1-(1-(5-chloro-2-methoxy-4- methyl-3-(5- (methylsu...) Show SMILES COc1c(cc(Cl)c(C)c1-c1cncc(c1)S(C)(=O)=O)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C22H23ClN6O3S/c1-11-17(23)7-16(13(3)29-22-19(12(2)28-29)21(24)26-10-27-22)20(32-4)18(11)14-6-15(9-25-8-14)33(5,30)31/h6-10,13H,1-5H3,(H2,24,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261150 (5-(3-(1-(4-amino-3-methyl-1H- pyrazolo[3,4-d]pyrim...) Show SMILES CNC(=O)c1ccc(cn1)-c1c(C)c(Cl)cc(C(C)n2nc(C)c3c(N)ncnc23)c1OC Show InChI InChI=1S/C23H24ClN7O2/c1-11-16(24)8-15(13(3)31-22-19(12(2)30-31)21(25)28-10-29-22)20(33-5)18(11)14-6-7-17(27-9-14)23(32)26-4/h6-10,13H,1-5H3,(H,26,32)(H2,25,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM289173 (US10092570, Example 174 | US11433071, Example 174 ...) Show SMILES COc1c(cc(Cl)c(C)c1-c1cncc(c1)C(=O)N(C)C1CC1)C(C)Nc1ncnc(N)c1C(C)=N Show InChI InChI=1S/C26H30ClN7O2/c1-13-20(27)9-19(15(3)33-25-22(14(2)28)24(29)31-12-32-25)23(36-5)21(13)16-8-17(11-30-10-16)26(35)34(4)18-6-7-18/h8-12,15,18,28H,6-7H2,1-5H3,(H3,29,31,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261152 (5-{3-[1-(4-amino-3-methyl-1H- pyrazolo[3,4-d]pyrim...) Show SMILES COc1c(cc(Cl)c(C)c1-c1cncc(c1)C(=O)N(C)CCO)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C25H28ClN7O3/c1-13-19(26)9-18(15(3)33-24-21(14(2)31-33)23(27)29-12-30-24)22(36-5)20(13)16-8-17(11-28-10-16)25(35)32(4)6-7-34/h8-12,15,34H,6-7H2,1-5H3,(H2,27,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261153 (1-[(5-{3-[1-(4-amino-3-methyl-1H- pyrazolo[3,4-d]p...) Show SMILES COc1c(cc(Cl)c(C)c1-c1cncc(c1)C(=O)N1CCC(O)CC1)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C27H30ClN7O3/c1-14-21(28)10-20(16(3)35-26-23(15(2)33-35)25(29)31-13-32-26)24(38-4)22(14)17-9-18(12-30-11-17)27(37)34-7-5-19(36)6-8-34/h9-13,16,19,36H,5-8H2,1-4H3,(H2,29,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261154 (1-[(5-{3-[1-(4-amino-3-methyl-1H- pyrazolo[3,4-d]p...) Show SMILES COc1c(cc(Cl)c(C)c1-c1cncc(c1)C(=O)N1CC(C1)C#N)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C26H25ClN8O2/c1-13-20(27)6-19(15(3)35-25-22(14(2)33-35)24(29)31-12-32-25)23(37-4)21(13)17-5-18(9-30-8-17)26(36)34-10-16(7-28)11-34/h5-6,8-9,12,15-16H,10-11H2,1-4H3,(H2,29,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair

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