Compile Data Set for Download or QSAR

Found 122 hits Enz. Inhib. hit(s) with all data for entry = 1415   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321411 (6-[(E)-but-2-enyl]-4-[3-methoxy-4-(morpholine-4-ca...) Show SMILES COc1cc(ccc1C(=O)N1CCOCC1)-c1cn(C\C=C\C)c(=O)c2[nH]c(C)cc12 Show InChI InChI=1S/C24H27N3O4/c1-4-5-8-27-15-20(19-13-16(2)25-22(19)24(27)29)17-6-7-18(21(14-17)30-3)23(28)26-9-11-31-12-10-26/h4-7,13-15,25H,8-12H2,1-3H3/b5-4+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321430 (6-[(E)-but-2-enyl]-4-[3-isopropoxy-4-(morpholine-4...) Show SMILES C\C=C\Cn1cc(-c2ccc(C(=O)N3CCOCC3)c(OC(C)C)c2)c2cc(C)[nH]c2c1=O Show InChI InChI=1S/C26H31N3O4/c1-5-6-9-29-16-22(21-14-18(4)27-24(21)26(29)31)19-7-8-20(23(15-19)33-17(2)3)25(30)28-10-12-32-13-11-28/h5-8,14-17,27H,9-13H2,1-4H3/b6-5+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321429 ((E)-1-(4-(6-(but-2-en-1-yl)-2-methyl-7-oxo-6,7-dih...) Show SMILES C\C=C\Cn1cc(-c2ccc(C(=O)N3CCC(CC3)C(N)=O)c(Cl)c2)c2cc(C)[nH]c2c1=O Show InChI InChI=1S/C25H27ClN4O3/c1-3-4-9-30-14-20(19-12-15(2)28-22(19)25(30)33)17-5-6-18(21(26)13-17)24(32)29-10-7-16(8-11-29)23(27)31/h3-6,12-14,16,28H,7-11H2,1-2H3,(H2,27,31)/b4-3+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321438 (3-[6-[(E)-but-2-enyl]-2-methyl-7-oxo-1H-pyrrolo[2,...) Show SMILES COc1ccc(cc1-c1cn(C\C=C\C)c(=O)c2[nH]c(C)cc12)C(=O)NCc1cncnc1 Show InChI InChI=1S/C25H25N5O3/c1-4-5-8-30-14-21(20-9-16(2)29-23(20)25(30)32)19-10-18(6-7-22(19)33-3)24(31)28-13-17-11-26-15-27-12-17/h4-7,9-12,14-15,29H,8,13H2,1-3H3,(H,28,31)/b5-4+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321432 ((E)-6-(but-2-en-1-yl)-4-(3-chloro-4-(piperazine-1-...) Show SMILES C\C=C\Cn1cc(-c2ccc(C(=O)N3CCNCC3)c(Cl)c2)c2cc(C)[nH]c2c1=O Show InChI InChI=1S/C23H25ClN4O2/c1-3-4-9-28-14-19(18-12-15(2)26-21(18)23(28)30)16-5-6-17(20(24)13-16)22(29)27-10-7-25-8-11-27/h3-6,12-14,25-26H,7-11H2,1-2H3/b4-3+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321424 (6-[(E)-but-2-enyl]-4-[2,5-dimethoxy-4-(morpholine-...) Show SMILES COc1cc(c(OC)cc1C(=O)N1CCOCC1)-c1cn(C\C=C\C)c(=O)c2[nH]c(C)cc12 Show InChI InChI=1S/C25H29N3O5/c1-5-6-7-28-15-20(18-12-16(2)26-23(18)25(28)30)17-13-22(32-4)19(14-21(17)31-3)24(29)27-8-10-33-11-9-27/h5-6,12-15,26H,7-11H2,1-4H3/b6-5+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321433 ((E)-4-(4-(3-(3-amino-1H-pyrazol-1-yl)azetidine-1-c...) Show SMILES C\C=C\Cn1cc(-c2ccc(C(=O)N3CC(C3)n3ccc(N)n3)c(Cl)c2)c2cc(C)[nH]c2c1=O Show InChI InChI=1S/C25H25ClN6O2/c1-3-4-8-30-14-20(19-10-15(2)28-23(19)25(30)34)16-5-6-18(21(26)11-16)24(33)31-12-17(13-31)32-9-7-22(27)29-32/h3-7,9-11,14,17,28H,8,12-13H2,1-2H3,(H2,27,29)/b4-3+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321412 (6-[(E)-but-2-enyl]-4-[3-chloro-4-(morpholine-4-car...) Show SMILES C\C=C\Cn1cc(-c2ccc(C(=O)N3CCOCC3)c(Cl)c2)c2cc(C)[nH]c2c1=O Show InChI InChI=1S/C23H24ClN3O3/c1-3-4-7-27-14-19(18-12-15(2)25-21(18)23(27)29)16-5-6-17(20(24)13-16)22(28)26-8-10-30-11-9-26/h3-6,12-14,25H,7-11H2,1-2H3/b4-3+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321431 (6-[(E)-but-2-enyl]-4-[3-(cyclopropylmethoxy)-4-(mo...) Show SMILES C\C=C\CN1C=C2NC(C)C=C2C(=C1)c1ccc(C(=O)N2CCOCC2)c(OCC2CC2)c1 |c:10,13,t:5| Show InChI InChI=1S/C27H33N3O3/c1-3-4-9-29-16-24(23-14-19(2)28-25(23)17-29)21-7-8-22(26(15-21)33-18-20-5-6-20)27(31)30-10-12-32-13-11-30/h3-4,7-8,14-17,19-20,28H,5-6,9-13,18H2,1-2H3/b4-3+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321422 (5-[6-[(E)-but-2-enyl]-2-methyl-7-oxo-1H-pyrrolo[2,...) Show SMILES C\C=C\Cn1cc(-c2ccc(C(=O)N3CCOCC3)c(c2)C#N)c2cc(C)[nH]c2c1=O Show InChI InChI=1S/C24H24N4O3/c1-3-4-7-28-15-21(20-12-16(2)26-22(20)24(28)30)17-5-6-19(18(13-17)14-25)23(29)27-8-10-31-11-9-27/h3-6,12-13,15,26H,7-11H2,1-2H3/b4-3+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321425 (3-[6-[(E)-but-2-enyl]-2-methyl-7-oxo-1H-pyrrolo[2,...) Show SMILES COc1ccc(cc1-c1cn(C\C=C\C)c(=O)c2[nH]c(C)cc12)C(=O)NCc1cnccn1 Show InChI InChI=1S/C25H25N5O3/c1-4-5-10-30-15-21(20-11-16(2)29-23(20)25(30)32)19-12-17(6-7-22(19)33-3)24(31)28-14-18-13-26-8-9-27-18/h4-9,11-13,15,29H,10,14H2,1-3H3,(H,28,31)/b5-4+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321437 ((E)-6-(but-2-en-1-yl)-4-(4-(2-hydroxypropan-2-yl)-...) Show SMILES COc1cc(c(OC)cc1-c1cn(C\C=C\C)c(=O)c2[nH]c(C)cc12)C(C)(C)O Show InChI InChI=1S/C23H28N2O4/c1-7-8-9-25-13-17(16-10-14(2)24-21(16)22(25)26)15-11-20(29-6)18(23(3,4)27)12-19(15)28-5/h7-8,10-13,24,27H,9H2,1-6H3/b8-7+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321428 (1-[4-[6-[(E)-but-2-enyl]-2-methyl-7-oxo-1H-pyrrolo...) Show SMILES C\C=C\Cn1cc(-c2ccc(C(=O)N3CCC(CC3)C(O)=O)c(Cl)c2)c2cc(C)[nH]c2c1=O Show InChI InChI=1S/C25H26ClN3O4/c1-3-4-9-29-14-20(19-12-15(2)27-22(19)24(29)31)17-5-6-18(21(26)13-17)23(30)28-10-7-16(8-11-28)25(32)33/h3-6,12-14,16,27H,7-11H2,1-2H3,(H,32,33)/b4-3+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321414 (6-[(E)-but-2-enyl]-4-[3-chloro-4-(4-methylpiperazi...) Show SMILES C\C=C\Cn1cc(-c2ccc(C(=O)N3CCN(C)CC3)c(Cl)c2)c2cc(C)[nH]c2c1=O Show InChI InChI=1S/C24H27ClN4O2/c1-4-5-8-29-15-20(19-13-16(2)26-22(19)24(29)31)17-6-7-18(21(25)14-17)23(30)28-11-9-27(3)10-12-28/h4-7,13-15,26H,8-12H2,1-3H3/b5-4+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321418 (6-allyl-4-[2,5-dimethoxy-4-(morpholine-4-carbonyl)...) Show SMILES COc1cc(c(OC)cc1C(=O)N1CCOCC1)-c1cn(CC=C)c(=O)c2[nH]c(C)cc12 Show InChI InChI=1S/C24H27N3O5/c1-5-6-27-14-19(17-11-15(2)25-22(17)24(27)29)16-12-21(31-4)18(13-20(16)30-3)23(28)26-7-9-32-10-8-26/h5,11-14,25H,1,6-10H2,2-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321436 (4-[4-[3-(3-aminopyrazol-1-yl)azetidine-1-carbonyl]...) Show SMILES C\C=C\Cn1cc(-c2ccc(cc2)C(=O)N2CC(C2)n2ccc(N)n2)c2cc(C)[nH]c2c1=O Show InChI InChI=1S/C25H26N6O2/c1-3-4-10-29-15-21(20-12-16(2)27-23(20)25(29)33)17-5-7-18(8-6-17)24(32)30-13-19(14-30)31-11-9-22(26)28-31/h3-9,11-12,15,19,27H,10,13-14H2,1-2H3,(H2,26,28)/b4-3+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321463 (6-(but-3-en-1-yl)-4-(3-(difluoromethoxy)-5-(morpho...) Show SMILES FC(F)Oc1cc(cc(c1)-c1cn(CCC=C)c(=O)c2[nH]ccc12)C(=O)N1CCOCC1 Show InChI InChI=1S/C23H23F2N3O4/c1-2-3-6-28-14-19(18-4-5-26-20(18)22(28)30)15-11-16(13-17(12-15)32-23(24)25)21(29)27-7-9-31-10-8-27/h2,4-5,11-14,23,26H,1,3,6-10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321409 (6-[(E)-but-2-enyl]-4-[3-chloro-4-(pyrrolidine-1-ca...) Show SMILES C\C=C\Cn1cc(-c2ccc(C(=O)N3CCCC3)c(Cl)c2)c2cc(C)[nH]c2c1=O Show InChI InChI=1S/C23H24ClN3O2/c1-3-4-9-27-14-19(18-12-15(2)25-21(18)23(27)29)16-7-8-17(20(24)13-16)22(28)26-10-5-6-11-26/h3-4,7-8,12-14,25H,5-6,9-11H2,1-2H3/b4-3+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321470 (6-but-3-enyl-4-[1-methyl-6-(morpholine-4-carbonyl)...) Show SMILES Cn1cnc2c(cc(cc12)C(=O)N1CCOCC1)-n1cc(CCC=C)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C24H25N5O3/c1-3-4-5-16-14-29(18-6-7-25-22(18)23(16)30)20-13-17(12-19-21(20)26-15-27(19)2)24(31)28-8-10-32-11-9-28/h3,6-7,12-15,25H,1,4-5,8-11H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321465 (6-but-3-enyl-4-[3-methyl-7-(morpholine-4-carbonyl)...) Show SMILES Cn1cnc2c(cc(cc12)-c1cn(CCC=C)c(=O)c2[nH]ccc12)C(=O)N1CCOCC1 Show InChI InChI=1S/C24H25N5O3/c1-3-4-7-29-14-19(17-5-6-25-22(17)24(29)31)16-12-18(21-20(13-16)27(2)15-26-21)23(30)28-8-10-32-11-9-28/h3,5-6,12-15,25H,1,4,7-11H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321476 (6-but-3-enyl-4-[4-fluoro-3-(morpholine-4-carbonyl)...) Show SMILES Cc1cc2c(cn(CCC=C)c(=O)c2[nH]1)-c1ccc(F)c(c1)C(=O)N1CCOCC1 Show InChI InChI=1S/C23H24FN3O3/c1-3-4-7-27-14-19(17-12-15(2)25-21(17)23(27)29)16-5-6-20(24)18(13-16)22(28)26-8-10-30-11-9-26/h3,5-6,12-14,25H,1,4,7-11H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321415 (6-[(E)-but-2-enyl]-2-methyl-4-[3-methyl-4-(morphol...) Show SMILES C\C=C\Cn1cc(-c2ccc(C(=O)N3CCOCC3)c(C)c2)c2cc(C)[nH]c2c1=O Show InChI InChI=1S/C24H27N3O3/c1-4-5-8-27-15-21(20-14-17(3)25-22(20)24(27)29)18-6-7-19(16(2)13-18)23(28)26-9-11-30-12-10-26/h4-7,13-15,25H,8-12H2,1-3H3/b5-4+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321465 (6-but-3-enyl-4-[3-methyl-7-(morpholine-4-carbonyl)...) Show SMILES Cn1cnc2c(cc(cc12)-c1cn(CCC=C)c(=O)c2[nH]ccc12)C(=O)N1CCOCC1 Show InChI InChI=1S/C24H25N5O3/c1-3-4-7-29-14-19(17-5-6-25-22(17)24(29)31)16-12-18(21-20(13-16)27(2)15-26-21)23(30)28-8-10-32-11-9-28/h3,5-6,12-15,25H,1,4,7-11H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321462 (6-but-3-enyl-4-[4-fluoro-3-(morpholine-4-carbonyl)...) Show SMILES Fc1ccc(cc1C(=O)N1CCOCC1)-c1cn(CCC=C)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C22H22FN3O3/c1-2-3-8-26-14-18(16-6-7-24-20(16)22(26)28)15-4-5-19(23)17(13-15)21(27)25-9-11-29-12-10-25/h2,4-7,13-14,24H,1,3,8-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321417 (6-allyl-4-[3-chloro-4-(morpholine-4-carbonyl)pheny...) Show SMILES Cc1cc2c(cn(CC=C)c(=O)c2[nH]1)-c1ccc(C(=O)N2CCOCC2)c(Cl)c1 Show InChI InChI=1S/C22H22ClN3O3/c1-3-6-26-13-18(17-11-14(2)24-20(17)22(26)28)15-4-5-16(19(23)12-15)21(27)25-7-9-29-10-8-25/h3-5,11-13,24H,1,6-10H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321474 (6-but-3-enyl-4-[4-chloro-3-(morpholine-4-carbonyl)...) Show SMILES Cc1cc2c(cn(CCC=C)c(=O)c2[nH]1)-c1ccc(Cl)c(c1)C(=O)N1CCOCC1 Show InChI InChI=1S/C23H24ClN3O3/c1-3-4-7-27-14-19(17-12-15(2)25-21(17)23(27)29)16-5-6-20(24)18(13-16)22(28)26-8-10-30-11-9-26/h3,5-6,12-14,25H,1,4,7-11H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321468 (6-but-3-enyl-4-[6-(morpholine-4-carbonyl)-1H-benzi...) Show SMILES C=CCCn1cc(-c2cc(cc3[nH]cnc23)C(=O)N2CCOCC2)c2cc[nH]c2c1=O Show InChI InChI=1S/C23H23N5O3/c1-2-3-6-28-13-18(16-4-5-24-21(16)23(28)30)17-11-15(12-19-20(17)26-14-25-19)22(29)27-7-9-31-10-8-27/h2,4-5,11-14,24H,1,3,6-10H2,(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321389 (6-[(E)-but-2-enyl]-4-[3-chloro-4-(morpholine-4-car...) Show SMILES C\C=C\Cn1cc(-c2ccc(C(=O)N3CCOCC3)c(Cl)c2)c2cc[nH]c2c1=O Show InChI InChI=1S/C22H22ClN3O3/c1-2-3-8-26-14-18(16-6-7-24-20(16)22(26)28)15-4-5-17(19(23)13-15)21(27)25-9-11-29-12-10-25/h2-7,13-14,24H,8-12H2,1H3/b3-2+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321407 (6-[(E)-but-2-enyl]-2-methyl-4-[4-(morpholine-4-car...) Show SMILES C\C=C\Cn1cc(-c2ccc(cc2)C(=O)N2CCOCC2)c2cc(C)[nH]c2c1=O Show InChI InChI=1S/C23H25N3O3/c1-3-4-9-26-15-20(19-14-16(2)24-21(19)23(26)28)17-5-7-18(8-6-17)22(27)25-10-12-29-13-11-25/h3-8,14-15,24H,9-13H2,1-2H3/b4-3+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321383 (6-but-2-enyl-4-[4-(morpholine-4-carbonyl)phenyl]-1...) Show SMILES CC=CCn1cc(-c2ccc(cc2)C(=O)N2CCOCC2)c2cc[nH]c2c1=O Show InChI InChI=1S/C22H23N3O3/c1-2-3-10-25-15-19(18-8-9-23-20(18)22(25)27)16-4-6-17(7-5-16)21(26)24-11-13-28-14-12-24/h2-9,15,23H,10-14H2,1H3/b3-2+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321408 (6-[(E)-but-2-enyl]-2-methyl-4-[4-(pyrrolidine-1-ca...) Show SMILES C\C=C\Cn1cc(-c2ccc(cc2)C(=O)N2CCCC2)c2cc(C)[nH]c2c1=O Show InChI InChI=1S/C23H25N3O2/c1-3-4-11-26-15-20(19-14-16(2)24-21(19)23(26)28)17-7-9-18(10-8-17)22(27)25-12-5-6-13-25/h3-4,7-10,14-15,24H,5-6,11-13H2,1-2H3/b4-3+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321467 (6-but-3-enyl-4-[3-ethyl-7-(morpholine-4-carbonyl)b...) Show SMILES CCn1cnc2c(cc(cc12)-c1cn(CCC=C)c(=O)c2[nH]ccc12)C(=O)N1CCOCC1 Show InChI InChI=1S/C25H27N5O3/c1-3-5-8-30-15-20(18-6-7-26-23(18)25(30)32)17-13-19(24(31)29-9-11-33-12-10-29)22-21(14-17)28(4-2)16-27-22/h3,6-7,13-16,26H,1,4-5,8-12H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321475 (6-but-3-enyl-4-[3-fluoro-5-(morpholine-4-carbonyl)...) Show SMILES Cc1cc2c(cn(CCC=C)c(=O)c2[nH]1)-c1cc(F)cc(c1)C(=O)N1CCOCC1 Show InChI InChI=1S/C23H24FN3O3/c1-3-4-5-27-14-20(19-10-15(2)25-21(19)23(27)29)16-11-17(13-18(24)12-16)22(28)26-6-8-30-9-7-26/h3,10-14,25H,1,4-9H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321402 (6-[(E)-but-2-enyl]-4-[4-(1-hydroxy-1-methyl-ethyl)...) Show SMILES C\C=C\Cn1cc(-c2ccc(cc2)C(C)(C)O)c2cc[nH]c2c1=O Show InChI InChI=1S/C20H22N2O2/c1-4-5-12-22-13-17(16-10-11-21-18(16)19(22)23)14-6-8-15(9-7-14)20(2,3)24/h4-11,13,21,24H,12H2,1-3H3/b5-4+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321458 (6-but-3-enyl-4-[3,4-difluoro-5-(morpholine-4-carbo...) Show SMILES Fc1cc(cc(C(=O)N2CCOCC2)c1F)-c1cn(CCC=C)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C22H21F2N3O3/c1-2-3-6-27-13-17(15-4-5-25-20(15)22(27)29)14-11-16(19(24)18(23)12-14)21(28)26-7-9-30-10-8-26/h2,4-5,11-13,25H,1,3,6-10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321439 (6-butyl-4-[2,5-dimethoxy-4-(morpholine-4-carbonyl)...) Show SMILES CCCCn1cc(-c2cc(OC)c(cc2OC)C(=O)N2CCOCC2)c2cc(C)[nH]c2c1=O Show InChI InChI=1S/C25H31N3O5/c1-5-6-7-28-15-20(18-12-16(2)26-23(18)25(28)30)17-13-22(32-4)19(14-21(17)31-3)24(29)27-8-10-33-11-9-27/h12-15,26H,5-11H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321459 (6-but-3-enyl-4-[3-fluoro-5-(3-methylmorpholine-4-c...) Show SMILES CC1COCCN1C(=O)c1cc(F)cc(c1)-c1cn(CCC=C)c(=O)c2[nH]ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321469 (4-(6-(but-3-en-1-yl)-7-oxo-6,7-dihydro-1H-pyrrolo[...) Show SMILES CN(C)C(=O)c1cc(-c2cn(CCC=C)c(=O)c3[nH]ccc23)c2nc[nH]c2c1 Show InChI InChI=1S/C21H21N5O2/c1-4-5-8-26-11-16(14-6-7-22-19(14)21(26)28)15-9-13(20(27)25(2)3)10-17-18(15)24-12-23-17/h4,6-7,9-12,22H,1,5,8H2,2-3H3,(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321400 (6-[(E)-but-2-enyl]-4-[4-(1-hydroxy-1-methyl-ethyl)...) Show SMILES COc1cc(ccc1-n1cc(C\C=C\C)c(=O)c2[nH]ccc12)C(C)(C)O Show InChI InChI=1S/C21H24N2O3/c1-5-6-7-14-13-23(17-10-11-22-19(17)20(14)24)16-9-8-15(21(2,3)25)12-18(16)26-4/h5-6,8-13,22,25H,7H2,1-4H3/b6-5+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321461 (6-but-3-enyl-4-[3-fluoro-5-(morpholine-4-carbonyl)...) Show SMILES Fc1cc(cc(c1)-c1cn(CCC=C)c(=O)c2[nH]ccc12)C(=O)N1CCOCC1 Show InChI InChI=1S/C22H22FN3O3/c1-2-3-6-26-14-19(18-4-5-24-20(18)22(26)28)15-11-16(13-17(23)12-15)21(27)25-7-9-29-10-8-25/h2,4-5,11-14,24H,1,3,6-10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321460 (3-(6-but-3-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...) Show SMILES C=CCCn1cc(-c2cc(cc(c2)C(=O)N2CCOCC2)C#N)c2cc[nH]c2c1=O Show InChI InChI=1S/C23H22N4O3/c1-2-3-6-27-15-20(19-4-5-25-21(19)23(27)29)17-11-16(14-24)12-18(13-17)22(28)26-7-9-30-10-8-26/h2,4-5,11-13,15,25H,1,3,6-10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321464 (6-but-3-enyl-4-[7-(morpholine-4-carbonyl)-3H-benzi...) Show SMILES C=CCCn1cc(-c2cc(C(=O)N3CCOCC3)c3nc[nH]c3c2)c2cc[nH]c2c1=O Show InChI InChI=1S/C23H23N5O3/c1-2-3-6-28-13-18(16-4-5-24-21(16)23(28)30)15-11-17(20-19(12-15)25-14-26-20)22(29)27-7-9-31-10-8-27/h2,4-5,11-14,24H,1,3,6-10H2,(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321381 (N-[4-(6-but-2-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-...) Show SMILES CC=CCn1cc(-c2ccc(NS(C)(=O)=O)cc2)c2cc[nH]c2c1=O Show InChI InChI=1S/C18H19N3O3S/c1-3-4-11-21-12-16(15-9-10-19-17(15)18(21)22)13-5-7-14(8-6-13)20-25(2,23)24/h3-10,12,19-20H,11H2,1-2H3/b4-3+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321420 (6-[(E)-but-2-enyl]-4-[4-chloro-5-(morpholine-4-car...) Show SMILES C\C=C\Cn1cc(-c2cc(Cl)c(cn2)C(=O)N2CCOCC2)c2cc(C)[nH]c2c1=O Show InChI InChI=1S/C22H23ClN4O3/c1-3-4-5-27-13-17(15-10-14(2)25-20(15)22(27)29)19-11-18(23)16(12-24-19)21(28)26-6-8-30-9-7-26/h3-4,10-13,25H,5-9H2,1-2H3/b4-3+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321396 (3-[6-[(E)-but-2-enyl]-7-oxo-1H-pyrrolo[2,3-c]pyrid...) Show SMILES COc1ccc(cc1-c1cn(C\C=C\C)c(=O)c2[nH]ccc12)C(=O)NCCN(C)C Show InChI InChI=1S/C23H28N4O3/c1-5-6-12-27-15-19(17-9-10-24-21(17)23(27)29)18-14-16(7-8-20(18)30-4)22(28)25-11-13-26(2)3/h5-10,14-15,24H,11-13H2,1-4H3,(H,25,28)/b6-5+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321398 (3-[6-[(E)-but-2-enyl]-7-oxo-1H-pyrrolo[2,3-c]pyrid...) Show SMILES CCCNC(=O)c1ccc(OC)c(c1)-c1cn(C\C=C\C)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C22H25N3O3/c1-4-6-12-25-14-18(16-9-11-23-20(16)22(25)27)17-13-15(7-8-19(17)28-3)21(26)24-10-5-2/h4,6-9,11,13-14,23H,5,10,12H2,1-3H3,(H,24,26)/b6-4+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321395 (3-[6-[(E)-but-2-enyl]-7-oxo-1H-pyrrolo[2,3-c]pyrid...) Show SMILES COc1ccc(cc1-c1cn(C\C=C\C)c(=O)c2[nH]ccc12)C(=O)NCC(C)C Show InChI InChI=1S/C23H27N3O3/c1-5-6-11-26-14-19(17-9-10-24-21(17)23(26)28)18-12-16(7-8-20(18)29-4)22(27)25-13-15(2)3/h5-10,12,14-15,24H,11,13H2,1-4H3,(H,25,27)/b6-5+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321392 (3-[6-[(E)-but-2-enyl]-7-oxo-1H-pyrrolo[2,3-c]pyrid...) Show SMILES CCNC(=O)c1ccc(OC)c(c1)-c1cn(C\C=C\C)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C21H23N3O3/c1-4-6-11-24-13-17(15-9-10-23-19(15)21(24)26)16-12-14(20(25)22-5-2)7-8-18(16)27-3/h4,6-10,12-13,23H,5,11H2,1-3H3,(H,22,25)/b6-4+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321377 (4-(6-but-2-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...) Show SMILES CNC(=O)c1ccc(cc1)-c1cn(CC=CC)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C19H19N3O2/c1-3-4-11-22-12-16(15-9-10-21-17(15)19(22)24)13-5-7-14(8-6-13)18(23)20-2/h3-10,12,21H,11H2,1-2H3,(H,20,23)/b4-3+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 [134-239] (Homo sapiens (Human))	BDBM321413 (6-[(E)-but-2-enyl]-4-[5-chloro-6-(morpholine-4-car...) Show SMILES C\C=C\Cn1cc(-c2cnc(C(=O)N3CCOCC3)c(Cl)c2)c2cc(C)[nH]c2c1=O Show InChI InChI=1S/C22H23ClN4O3/c1-3-4-5-27-13-17(16-10-14(2)25-19(16)21(27)28)15-11-18(23)20(24-12-15)22(29)26-6-8-30-9-7-26/h3-4,10-13,25H,5-9H2,1-2H3/b4-3+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair

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