Compile Data Set for Download or QSAR

Found 136 hits Enz. Inhib. hit(s) with all data for entry = 1535   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330195 (3-Chloro-N-[4-[[(1R,4R)-5-oxa-2-azabicyclo[2.2.1]h...) Show SMILES Clc1cccc(c1)C(=O)Nc1ccc(C[C@@]23CN[C@@H](CO2)C3)cc1 |r| Show InChI InChI=1S/C19H19ClN2O2/c20-15-3-1-2-14(8-15)18(23)22-16-6-4-13(5-7-16)9-19-10-17(11-24-19)21-12-19/h1-8,17,21H,9-12H2,(H,22,23)/t17-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330161 ((RS)-4-Chloro-N-[4-(5-oxa-2-azabicyclo[2.2.2]octan...) Show SMILES Clc1ccc(cc1)C(=O)Nc1ccc(cc1)C12CCC(CO1)NC2 Show InChI InChI=1S/C19H19ClN2O2/c20-15-5-1-13(2-6-15)18(23)22-16-7-3-14(4-8-16)19-10-9-17(11-24-19)21-12-19/h1-8,17,21H,9-12H2,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330177 (4-Chloro-N-[4-[[(1R,4R)-5-oxa-2-azabicyclo[2.2.1]h...) Show SMILES Clc1ccc(cc1)C(=O)Nc1ccc(C[C@@]23CN[C@@H](CO2)C3)cc1 |r| Show InChI InChI=1S/C19H19ClN2O2/c20-15-5-3-14(4-6-15)18(23)22-16-7-1-13(2-8-16)9-19-10-17(11-24-19)21-12-19/h1-8,17,21H,9-12H2,(H,22,23)/t17-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330211 (3-Chloro-N-[4-[(1R,4S)-5-oxa-2-azabicyclo[2.2.1]he...) Show SMILES Clc1cccc(c1)C(=O)Nc1ccc(cc1)[C@@]12CN[C@@H](CO1)C2 |r| Show InChI InChI=1S/C18H17ClN2O2/c19-14-3-1-2-12(8-14)17(22)21-15-6-4-13(5-7-15)18-9-16(10-23-18)20-11-18/h1-8,16,20H,9-11H2,(H,21,22)/t16-,18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330162 (3-Chloro-N-[4-(5-oxa-2-azabicyclo[2.2.2]octan-4-yl...) Show SMILES Clc1cccc(c1)C(=O)Nc1ccc(cc1)C12CCC(CO1)NC2 Show InChI InChI=1S/C19H19ClN2O2/c20-15-3-1-2-13(10-15)18(23)22-16-6-4-14(5-7-16)19-9-8-17(11-24-19)21-12-19/h1-7,10,17,21H,8-9,11-12H2,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330200 (1-[4-[[(1R,4R)-5-Oxa-2-azabicyclo[2.2.1]heptan-4-y...) Show SMILES FC(F)(F)c1cccc(NC(=O)Nc2ccc(C[C@@]34CN[C@@H](CO3)C4)cc2)c1 |r| Show InChI InChI=1S/C20H20F3N3O2/c21-20(22,23)14-2-1-3-16(8-14)26-18(27)25-15-6-4-13(5-7-15)9-19-10-17(11-28-19)24-12-19/h1-8,17,24H,9-12H2,(H2,25,26,27)/t17-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330222 ((RS)-1-(4-Chlorophenyl)-3-[4-(5-oxa-2-azabicyclo[2...) Show SMILES Clc1ccc(NC(=O)Nc2ccc(cc2)C23CCC(CO2)NC3)cc1 Show InChI InChI=1S/C19H20ClN3O2/c20-14-3-7-16(8-4-14)23-18(24)22-15-5-1-13(2-6-15)19-10-9-17(11-25-19)21-12-19/h1-8,17,21H,9-12H2,(H2,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330215 (3-Chloro-N-[4-[(1S,4R)-5-oxa-2-azabicyclo[2.2.1]he...) Show SMILES Clc1cccc(c1)C(=O)Nc1ccc(cc1)[C@]12CN[C@H](CO1)C2 |r| Show InChI InChI=1S/C18H17ClN2O2/c19-14-3-1-2-12(8-14)17(22)21-15-6-4-13(5-7-15)18-9-16(10-23-18)20-11-18/h1-8,16,20H,9-11H2,(H,21,22)/t16-,18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330210 (4-Chloro-N-[4-[(1R,4S)-5-oxa-2-azabicyclo[2.2.1]he...) Show SMILES Clc1ccc(cc1)C(=O)Nc1ccc(cc1)[C@@]12CN[C@@H](CO1)C2 |r| Show InChI InChI=1S/C18H17ClN2O2/c19-14-5-1-12(2-6-14)17(22)21-15-7-3-13(4-8-15)18-9-16(10-23-18)20-11-18/h1-8,16,20H,9-11H2,(H,21,22)/t16-,18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330201 (4-(Cyclopropylmethoxy)-N-[4-[[(1R,4R)-5-oxa-2-azab...) Show SMILES O=C(Nc1ccc(C[C@@]23CN[C@@H](CO2)C3)cc1)c1ccc(OCC2CC2)cc1 |r| Show InChI InChI=1S/C23H26N2O3/c26-22(18-5-9-21(10-6-18)27-13-17-1-2-17)25-19-7-3-16(4-8-19)11-23-12-20(14-28-23)24-15-23/h3-10,17,20,24H,1-2,11-15H2,(H,25,26)/t20-,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330176 (5-Chloro-N-[4-[(1R,4S)-5-oxa-2-azabicyclo[2.2.1]he...) Show SMILES Clc1ccc(Nc2ccc(cc2)[C@@]23CN[C@@H](CO2)C3)nc1 |r| Show InChI InChI=1S/C16H16ClN3O/c17-12-3-6-15(18-8-12)20-13-4-1-11(2-5-13)16-7-14(9-21-16)19-10-16/h1-6,8,14,19H,7,9-10H2,(H,18,20)/t14-,16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330205 (4-Ethoxy-N-[4-[[(1R,4R)-5-oxa-2-azabicyclo[2.2.1]h...) Show SMILES CCOc1ccc(cc1)C(=O)Nc1ccc(C[C@@]23CN[C@@H](CO2)C3)cc1 |r| Show InChI InChI=1S/C21H24N2O3/c1-2-25-19-9-5-16(6-10-19)20(24)23-17-7-3-15(4-8-17)11-21-12-18(13-26-21)22-14-21/h3-10,18,22H,2,11-14H2,1H3,(H,23,24)/t18-,21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330180 (1-(3-Chlorophenyl)-3-[4-[[(1R,4R)-5-oxa-2-azabicyc...) Show SMILES Clc1cccc(NC(=O)Nc2ccc(C[C@@]34CN[C@@H](CO3)C4)cc2)c1 |r| Show InChI InChI=1S/C19H20ClN3O2/c20-14-2-1-3-16(8-14)23-18(24)22-15-6-4-13(5-7-15)9-19-10-17(11-25-19)21-12-19/h1-8,17,21H,9-12H2,(H2,22,23,24)/t17-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM330203 (N-[4-[[(1R,4R)-5-Oxa-2-azabicyclo[2.2.1]heptan-4-y...) Show SMILES FC(F)(F)COc1ccc(cn1)C(=O)Nc1ccc(C[C@@]23CN[C@@H](CO2)C3)cc1 |r| Show InChI InChI=1S/C20H20F3N3O3/c21-20(22,23)12-28-17-6-3-14(9-24-17)18(27)26-15-4-1-13(2-5-15)7-19-8-16(10-29-19)25-11-19/h1-6,9,16,25H,7-8,10-12H2,(H,26,27)/t16-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10.4	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330203 (N-[4-[[(1R,4R)-5-Oxa-2-azabicyclo[2.2.1]heptan-4-y...) Show SMILES FC(F)(F)COc1ccc(cn1)C(=O)Nc1ccc(C[C@@]23CN[C@@H](CO2)C3)cc1 |r| Show InChI InChI=1S/C20H20F3N3O3/c21-20(22,23)12-28-17-6-3-14(9-24-17)18(27)26-15-4-1-13(2-5-15)7-19-8-16(10-29-19)25-11-19/h1-6,9,16,25H,7-8,10-12H2,(H,26,27)/t16-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10.4	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330219 (N-[4-[[(1R,4R)-5-Oxa-2-azabicyclo[2.2.1]heptan-4-y...) Show SMILES FC(F)(F)c1ccc(Nc2ccc(C[C@@]34CN[C@@H](CO3)C4)cc2)nc1 |r| Show InChI InChI=1S/C18H18F3N3O/c19-18(20,21)13-3-6-16(22-9-13)24-14-4-1-12(2-5-14)7-17-8-15(10-25-17)23-11-17/h1-6,9,15,23H,7-8,10-11H2,(H,22,24)/t15-,17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10.7	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM330200 (1-[4-[[(1R,4R)-5-Oxa-2-azabicyclo[2.2.1]heptan-4-y...) Show SMILES FC(F)(F)c1cccc(NC(=O)Nc2ccc(C[C@@]34CN[C@@H](CO3)C4)cc2)c1 |r| Show InChI InChI=1S/C20H20F3N3O2/c21-20(22,23)14-2-1-3-16(8-14)26-18(27)25-15-6-4-13(5-7-15)9-19-10-17(11-28-19)24-12-19/h1-8,17,24H,9-12H2,(H2,25,26,27)/t17-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10.8	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330160 ((RS)—N-[4-(5-Oxa-2-azabicyclo[2.2.2]octan-4-y...) Show SMILES FC(F)(F)c1ccc(Nc2ccc(cc2)C23CCC(CO2)NC3)nc1 Show InChI InChI=1S/C18H18F3N3O/c19-18(20,21)13-3-6-16(22-9-13)24-14-4-1-12(2-5-14)17-8-7-15(10-25-17)23-11-17/h1-6,9,15,23H,7-8,10-11H2,(H,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11.1	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330224 ((RS)-1-(3-Chlorophenyl)-3-[4-(5-oxa-2-azabicyclo[2...) Show SMILES Clc1cccc(NC(=O)Nc2ccc(cc2)C23CCC(CO2)NC3)c1 Show InChI InChI=1S/C19H20ClN3O2/c20-14-2-1-3-16(10-14)23-18(24)22-15-6-4-13(5-7-15)19-9-8-17(11-25-19)21-12-19/h1-7,10,17,21H,8-9,11-12H2,(H2,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11.9	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330199 (1-(2-Chlorophenyl)-3-[4-[[(1R,4R)-5-oxa-2-azabicyc...) Show SMILES Clc1ccccc1NC(=O)Nc1ccc(C[C@@]23CN[C@@H](CO2)C3)cc1 |r| Show InChI InChI=1S/C19H20ClN3O2/c20-16-3-1-2-4-17(16)23-18(24)22-14-7-5-13(6-8-14)9-19-10-15(11-25-19)21-12-19/h1-8,15,21H,9-12H2,(H2,22,23,24)/t15-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.4	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330178 (1-[4-[[(1R,4R)-5-Oxa-2-azabicyclo[2.2.1]heptan-4-y...) Show SMILES FC(F)(F)c1ccc(NC(=O)Nc2ccc(C[C@@]34CN[C@@H](CO3)C4)cc2)cc1 |r| Show InChI InChI=1S/C20H20F3N3O2/c21-20(22,23)14-3-7-16(8-4-14)26-18(27)25-15-5-1-13(2-6-15)9-19-10-17(11-28-19)24-12-19/h1-8,17,24H,9-12H2,(H2,25,26,27)/t17-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.6	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM330183 (N-[4-[[(1 S,4S)-5-Oxa-2-azabicyclo[2.2.1]heptan-4-...) Show SMILES FC(F)(F)COc1ccc(cn1)C(=O)Nc1ccc(C[C@]23CN[C@H](CO2)C3)cc1 |r| Show InChI InChI=1S/C20H20F3N3O3/c21-20(22,23)12-28-17-6-3-14(9-24-17)18(27)26-15-4-1-13(2-5-15)7-19-8-16(10-29-19)25-11-19/h1-6,9,16,25H,7-8,10-12H2,(H,26,27)/t16-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330190 ((RS)-4-Chloro-N-[4-(5-oxa-2-azabicyclo[2.2.2]octan...) Show SMILES CCCc1n[nH]c(C(=O)Nc2ccc(cc2)C23CCC(CO2)NC3)c1Cl Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13.5	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330179 (1-(4-Chlorophenyl)-3-[4-[[(1R,4R)-5-oxa-2-azabicyc...) Show SMILES Clc1ccc(NC(=O)Nc2ccc(C[C@@]34CN[C@@H](CO3)C4)cc2)cc1 |r| Show InChI InChI=1S/C19H20ClN3O2/c20-14-3-7-16(8-4-14)23-18(24)22-15-5-1-13(2-6-15)9-19-10-17(11-25-19)21-12-19/h1-8,17,21H,9-12H2,(H2,22,23,24)/t17-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13.7	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330223 ((RS)-1-[4-(5-Oxa-2-azabicyclo[2.2.2]octan-4-yl)phe...) Show SMILES FC(F)(F)c1ccc(NC(=O)Nc2ccc(cc2)C23CCC(CO2)NC3)cc1 Show InChI InChI=1S/C20H20F3N3O2/c21-20(22,23)14-3-7-16(8-4-14)26-18(27)25-15-5-1-13(2-6-15)19-10-9-17(11-28-19)24-12-19/h1-8,17,24H,9-12H2,(H2,25,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13.7	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330159 ((RS)-5-Chloro-N-[4-(5-oxa-2-azabicyclo[2.2.2]octan...) Show SMILES Clc1ccc(Nc2ccc(cc2)C23CCC(CO2)NC3)nc1 Show InChI InChI=1S/C17H18ClN3O/c18-13-3-6-16(19-9-13)21-14-4-1-12(2-5-14)17-8-7-15(10-22-17)20-11-17/h1-6,9,15,20H,7-8,10-11H2,(H,19,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14.1	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330202 (6-Ethoxy-N-[4-[[(1R,4R)-5-oxa-2-azabicyclo[2.2.1]h...) Show SMILES CCOc1ccc(cn1)C(=O)Nc1ccc(C[C@@]23CN[C@@H](CO2)C3)cc1 |r| Show InChI InChI=1S/C20H23N3O3/c1-2-25-18-8-5-15(11-21-18)19(24)23-16-6-3-14(4-7-16)9-20-10-17(12-26-20)22-13-20/h3-8,11,17,22H,2,9-10,12-13H2,1H3,(H,23,24)/t17-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14.2	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330217 (N-[4-[(1 S,4R)-5-Oxa-2-azabicyclo[2.2.1]heptan-4-y...) Show SMILES FC(F)(F)c1ccc(Nc2ccc(cc2)[C@]23CN[C@H](CO2)C3)nc1 |r| Show InChI InChI=1S/C17H16F3N3O/c18-17(19,20)12-3-6-15(21-8-12)23-13-4-1-11(2-5-13)16-7-14(9-24-16)22-10-16/h1-6,8,14,22H,7,9-10H2,(H,21,23)/t14-,16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14.6	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330204 (4-Chloro-3-cyclopropyl-N-[4-[[(1R,4R)-5-oxa-2-azab...) Show SMILES Clc1c(n[nH]c1C(=O)Nc1ccc(C[C@@]23CN[C@@H](CO2)C3)cc1)C1CC1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14.7	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330209 (4-Ethoxy-N-[4-(5-oxa-2-azabicyclo[2.2.2]octan-4-yl...) Show SMILES CCOc1ccc(cc1)C(=O)Nc1ccc(cc1)C12CCC(CO1)NC2 Show InChI InChI=1S/C21H24N2O3/c1-2-25-19-9-3-15(4-10-19)20(24)23-17-7-5-16(6-8-17)21-12-11-18(13-26-21)22-14-21/h3-10,18,22H,2,11-14H2,1H3,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15.6	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330198 (5-Chloro-N-[4-[[(1R,4R)-5-oxa-2-azabicyclo[2.2.1]h...) Show SMILES Clc1ccc(Nc2ccc(C[C@@]34CN[C@@H](CO3)C4)cc2)nc1 |r| Show InChI InChI=1S/C17H18ClN3O/c18-13-3-6-16(19-9-13)21-14-4-1-12(2-5-14)7-17-8-15(10-22-17)20-11-17/h1-6,9,15,20H,7-8,10-11H2,(H,19,21)/t15-,17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15.8	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330214 (4-Chloro-N-[4-[(1S,4R)-5-oxa-2-azabicyclo[2.2.1]he...) Show SMILES Clc1ccc(cc1)C(=O)Nc1ccc(cc1)[C@]12CN[C@H](CO1)C2 |r| Show InChI InChI=1S/C18H17ClN2O2/c19-14-5-1-12(2-6-14)17(22)21-15-7-3-13(4-8-15)18-9-16(10-23-18)20-11-18/h1-8,16,20H,9-11H2,(H,21,22)/t16-,18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM330181 (4-(Cyclopropylmethoxy)-N-[4-[[(1S,4S)-5-oxa-2-azab...) Show SMILES O=C(Nc1ccc(C[C@]23CN[C@H](CO2)C3)cc1)c1ccc(OCC2CC2)cc1 |r| Show InChI InChI=1S/C23H26N2O3/c26-22(18-5-9-21(10-6-18)27-13-17-1-2-17)25-19-7-3-16(4-8-19)11-23-12-20(14-28-23)24-15-23/h3-10,17,20,24H,1-2,11-15H2,(H,25,26)/t20-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.5	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330197 (4-Chloro-N-[4-[[(1R,4R)-5-oxa-2-azabicyclo[2.2.1]h...) Show SMILES CCCc1n[nH]c(C(=O)Nc2ccc(C[C@@]34CN[C@@H](CO3)C4)cc2)c1Cl |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18.3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330167 ((RS)-4-(Cyclopropylmethoxy)-N-[4-(5-oxa-2-azabicyc...) Show SMILES O=C(Nc1ccc(cc1)C12CCC(CO1)NC2)c1ccc(OCC2CC2)cc1 Show InChI InChI=1S/C23H26N2O3/c26-22(17-3-9-21(10-4-17)27-13-16-1-2-16)25-19-7-5-18(6-8-19)23-12-11-20(14-28-23)24-15-23/h3-10,16,20,24H,1-2,11-15H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM330166 (1-[4-[[(1S,4S)-5-Oxa-2-azabicyclo[2.2.1]heptan-4-y...) Show SMILES FC(F)(F)c1cccc(NC(=O)Nc2ccc(C[C@]34CN[C@H](CO3)C4)cc2)c1 |r| Show InChI InChI=1S/C20H20F3N3O2/c21-20(22,23)14-2-1-3-16(8-14)26-18(27)25-15-6-4-13(5-7-15)9-19-10-17(11-28-19)24-12-19/h1-8,17,24H,9-12H2,(H2,25,26,27)/t17-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20.9	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM330201 (4-(Cyclopropylmethoxy)-N-[4-[[(1R,4R)-5-oxa-2-azab...) Show SMILES O=C(Nc1ccc(C[C@@]23CN[C@@H](CO2)C3)cc1)c1ccc(OCC2CC2)cc1 |r| Show InChI InChI=1S/C23H26N2O3/c26-22(18-5-9-21(10-6-18)27-13-17-1-2-17)25-19-7-3-16(4-8-19)11-23-12-20(14-28-23)24-15-23/h3-10,17,20,24H,1-2,11-15H2,(H,25,26)/t20-,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21.2	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330168 ((RS)-6-Ethoxy-N-[4-(5-oxa-2-azabicyclo[2.2.2]octan...) Show SMILES CCOc1ccc(cn1)C(=O)Nc1ccc(cc1)C12CCC(CO1)NC2 Show InChI InChI=1S/C20H23N3O3/c1-2-25-18-8-3-14(11-21-18)19(24)23-16-6-4-15(5-7-16)20-10-9-17(12-26-20)22-13-20/h3-8,11,17,22H,2,9-10,12-13H2,1H3,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21.9	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM330178 (1-[4-[[(1R,4R)-5-Oxa-2-azabicyclo[2.2.1]heptan-4-y...) Show SMILES FC(F)(F)c1ccc(NC(=O)Nc2ccc(C[C@@]34CN[C@@H](CO3)C4)cc2)cc1 |r| Show InChI InChI=1S/C20H20F3N3O2/c21-20(22,23)14-3-7-16(8-4-14)26-18(27)25-15-5-1-13(2-6-15)9-19-10-17(11-28-19)24-12-19/h1-8,17,24H,9-12H2,(H2,25,26,27)/t17-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23.7	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM330223 ((RS)-1-[4-(5-Oxa-2-azabicyclo[2.2.2]octan-4-yl)phe...) Show SMILES FC(F)(F)c1ccc(NC(=O)Nc2ccc(cc2)C23CCC(CO2)NC3)cc1 Show InChI InChI=1S/C20H20F3N3O2/c21-20(22,23)14-3-7-16(8-4-14)26-18(27)25-15-5-1-13(2-6-15)19-10-9-17(11-28-19)24-12-19/h1-8,17,24H,9-12H2,(H2,25,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26.3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM330217 (N-[4-[(1 S,4R)-5-Oxa-2-azabicyclo[2.2.1]heptan-4-y...) Show SMILES FC(F)(F)c1ccc(Nc2ccc(cc2)[C@]23CN[C@H](CO2)C3)nc1 |r| Show InChI InChI=1S/C17H16F3N3O/c18-17(19,20)12-3-6-15(21-8-12)23-13-4-1-11(2-5-13)16-7-14(9-24-16)22-10-16/h1-6,8,14,22H,7,9-10H2,(H,21,23)/t14-,16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	29.3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330198 (5-Chloro-N-[4-[[(1R,4R)-5-oxa-2-azabicyclo[2.2.1]h...) Show SMILES Clc1ccc(Nc2ccc(C[C@@]34CN[C@@H](CO3)C4)cc2)nc1 |r| Show InChI InChI=1S/C17H18ClN3O/c18-13-3-6-16(19-9-13)21-14-4-1-12(2-5-14)7-17-8-15(10-22-17)20-11-17/h1-6,9,15,20H,7-8,10-11H2,(H,19,21)/t15-,17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330169 ((RS)—N-[4-(5-Oxa-2-azabicyclo[2.2.2]octan-4-y...) Show SMILES FC(F)(F)COc1ccc(cn1)C(=O)Nc1ccc(cc1)C12CCC(CO1)NC2 Show InChI InChI=1S/C20H20F3N3O3/c21-20(22,23)12-28-17-6-1-13(9-24-17)18(27)26-15-4-2-14(3-5-15)19-8-7-16(10-29-19)25-11-19/h1-6,9,16,25H,7-8,10-12H2,(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30.4	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM330179 (1-(4-Chlorophenyl)-3-[4-[[(1R,4R)-5-oxa-2-azabicyc...) Show SMILES Clc1ccc(NC(=O)Nc2ccc(C[C@@]34CN[C@@H](CO3)C4)cc2)cc1 |r| Show InChI InChI=1S/C19H20ClN3O2/c20-14-3-7-16(8-4-14)23-18(24)22-15-5-1-13(2-6-15)9-19-10-17(11-25-19)21-12-19/h1-8,17,21H,9-12H2,(H2,22,23,24)/t17-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	37.5	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330193 ((RS)—N-[4-(5-Oxa-2-azabicyclo[2.2.2]octan-4-y...) Show SMILES FC(F)(F)c1cc(ccn1)C(=O)Nc1ccc(cc1)C12CCC(CO1)NC2 Show InChI InChI=1S/C19H18F3N3O2/c20-19(21,22)16-9-12(6-8-23-16)17(26)25-14-3-1-13(2-4-14)18-7-5-15(10-27-18)24-11-18/h1-4,6,8-9,15,24H,5,7,10-11H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	37.7	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330212 (N-[4-[(1R,4S)-5-Oxa-2-azabicyclo[2.2.1]heptan-4-yl...) Show SMILES FC(F)(F)c1nccc(Nc2ccc(cc2)[C@@]23CN[C@@H](CO2)C3)n1 |r| Show InChI InChI=1S/C16H15F3N4O/c17-16(18,19)14-20-6-5-13(23-14)22-11-3-1-10(2-4-11)15-7-12(8-24-15)21-9-15/h1-6,12,21H,7-9H2,(H,20,22,23)/t12-,15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	39.3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330163 (5-Chloro-N-[4-[(1S,4R)-5-oxa-2-azabicyclo[2.2.1]he...) Show SMILES Clc1ccc(Nc2ccc(cc2)[C@]23CN[C@H](CO2)C3)nc1 |r| Show InChI InChI=1S/C16H16ClN3O/c17-12-3-6-15(18-8-12)20-13-4-1-11(2-5-13)16-7-14(9-21-16)19-10-16/h1-6,8,14,19H,7,9-10H2,(H,18,20)/t14-,16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	41.4	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM330164 (1-[4-[[(1S,4S)-5-Oxa-2-azabicyclo[2.2.1]heptan-4-y...) Show SMILES FC(F)(F)c1ccc(NC(=O)Nc2ccc(C[C@]34CN[C@H](CO3)C4)cc2)cc1 |r| Show InChI InChI=1S/C20H20F3N3O2/c21-20(22,23)14-3-7-16(8-4-14)26-18(27)25-15-5-1-13(2-6-15)9-19-10-17(11-28-19)24-12-19/h1-8,17,24H,9-12H2,(H2,25,26,27)/t17-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	44.2	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM330222 ((RS)-1-(4-Chlorophenyl)-3-[4-(5-oxa-2-azabicyclo[2...) Show SMILES Clc1ccc(NC(=O)Nc2ccc(cc2)C23CCC(CO2)NC3)cc1 Show InChI InChI=1S/C19H20ClN3O2/c20-14-3-7-16(8-4-14)23-18(24)22-15-5-1-13(2-6-15)19-10-9-17(11-25-19)21-12-19/h1-8,17,21H,9-12H2,(H2,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	46.5	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330192 (N-[4-(5-Oxa-2-azabicyclo[2.2.2]octan-4-yl)phenyl]-...) Show SMILES FC(F)(F)c1nccc(Nc2ccc(cc2)C23CCC(CO2)NC3)n1 Show InChI InChI=1S/C17H17F3N4O/c18-17(19,20)15-21-8-6-14(24-15)23-12-3-1-11(2-4-12)16-7-5-13(9-25-16)22-10-16/h1-4,6,8,13,22H,5,7,9-10H2,(H,21,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	47.1	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair

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