Compile Data Set for Download or QSAR

Found 123 hits Enz. Inhib. hit(s) with all data for entry = 2436   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM365349 (US10633373, Example 54 | US10669265, Example 54 | ...) Show SMILES COC(=O)CCCC[S@](C)(=O)=NC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3cc(C)ccc3F)ccc2s1 |r| Show InChI InChI=1S/C29H30FN5O5S2/c1-17-7-9-22(30)23(12-17)34-29(38)33-20-8-10-24-18(13-20)15-25(41-24)21-14-19(16-32-27(21)31)28(37)35-42(3,39)11-5-4-6-26(36)40-2/h7-10,12-16H,4-6,11H2,1-3H3,(H2,31,32)(H2,33,34,38)/t42-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM363234 (6-amino-5-[5-({[(3-chloro-4- fluorophenyl)amino]ca...) Show SMILES CS(C)(=O)=NC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3ccc(F)c(Cl)c3)ccc2s1 Show InChI InChI=1S/C23H19ClFN5O3S2/c1-35(2,33)30-22(31)13-8-16(21(26)27-11-13)20-9-12-7-14(4-6-19(12)34-20)28-23(32)29-15-3-5-18(25)17(24)10-15/h3-11H,1-2H3,(H2,26,27)(H2,28,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM365350 (US10633373, Example 55 | US10669265, Example 55 | ...) Show SMILES COC(=O)CCCC[S@](C)(=O)=NC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3ccc(F)c(Cl)c3)ccc2s1 |r| Show InChI InChI=1S/C28H27ClFN5O5S2/c1-40-25(36)5-3-4-10-42(2,39)35-27(37)17-12-20(26(31)32-15-17)24-13-16-11-18(7-9-23(16)41-24)33-28(38)34-19-6-8-22(30)21(29)14-19/h6-9,11-15H,3-5,10H2,1-2H3,(H2,31,32)(H2,33,34,38)/t42-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM365348 (US10633373, Example 53 | US10669265, Example 53 | ...) Show SMILES COC(=O)CCCC[S@](C)(=O)=NC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3cccc(C)c3)ccc2s1 |r| Show InChI InChI=1S/C29H31N5O5S2/c1-18-7-6-8-21(13-18)32-29(37)33-22-10-11-24-19(14-22)16-25(40-24)23-15-20(17-31-27(23)30)28(36)34-41(3,38)12-5-4-9-26(35)39-2/h6-8,10-11,13-17H,4-5,9,12H2,1-3H3,(H2,30,31)(H2,32,33,37)/t41-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM364984 (6-amino-N-[dimethyl(oxido)- lambda4-sulfanylidene]...) Show SMILES CS(C)(=O)=NC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3cc(ccc3F)C(F)(F)F)ccc2s1 Show InChI InChI=1S/C24H19F4N5O3S2/c1-38(2,36)33-22(34)13-8-16(21(29)30-11-13)20-9-12-7-15(4-6-19(12)37-20)31-23(35)32-18-10-14(24(26,27)28)3-5-17(18)25/h3-11H,1-2H3,(H2,29,30)(H2,31,32,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM365355 (6-amino-N-[dimethyl(oxido)- lambda4-sulfanylidene]...) Show SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2cc(cnc2N)C(=O)N=S(C)(C)=O)c1 Show InChI InChI=1S/C22H22FN5O3S/c1-13-4-9-18(23)19(10-13)27-22(30)26-16-7-5-14(6-8-16)17-11-15(12-25-20(17)24)21(29)28-32(2,3)31/h4-12H,1-3H3,(H2,24,25)(H2,26,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM364980 (6-amino-5-{5-[({[4-chloro-3- (trifluoromethyl)phen...) Show SMILES CS(C)(=O)=NC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)ccc2s1 Show InChI InChI=1S/C24H19ClF3N5O3S2/c1-38(2,36)33-22(34)13-8-16(21(29)30-11-13)20-9-12-7-14(4-6-19(12)37-20)31-23(35)32-15-3-5-18(25)17(10-15)24(26,27)28/h3-11H,1-2H3,(H2,29,30)(H2,31,32,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM365352 (N-[dimethyl(oxido)-lambda4- sulfanylidene]-5-{5-[(...) Show SMILES CS(C)(=O)=NC(=O)c1cncc(c1)-c1cc2cc(NC(=O)Nc3cc(ccc3F)C(F)(F)F)ccc2s1 Show InChI InChI=1S/C24H18F4N4O3S2/c1-37(2,35)32-22(33)15-7-14(11-29-12-15)21-9-13-8-17(4-6-20(13)36-21)30-23(34)31-19-10-16(24(26,27)28)3-5-18(19)25/h3-12H,1-2H3,(H2,30,31,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM365369 (US10633373, Example 74 | US10669265, Example 74 | ...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1ccc(NC(=O)Nc2cc(ccc2F)C(F)(F)F)cc1 Show InChI InChI=1S/C21H16F4N4O3/c1-32-19(30)12-8-15(18(26)27-10-12)11-2-5-14(6-3-11)28-20(31)29-17-9-13(21(23,24)25)4-7-16(17)22/h2-10H,1H3,(H2,26,27)(H2,28,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM365370 (US10633373, Example 75 | US10669265, Example 75 | ...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1ccc(NC(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)cc1 Show InChI InChI=1S/C21H16ClF3N4O3/c1-32-19(30)12-8-15(18(26)27-10-12)11-2-4-13(5-3-11)28-20(31)29-14-6-7-17(22)16(9-14)21(23,24)25/h2-10H,1H3,(H2,26,27)(H2,28,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM364986 (US10633373, Example 7 | US10669265, Example 7 | US...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3cccc(c3)C(F)(F)F)ccc2s1 Show InChI InChI=1S/C23H17F3N4O3S/c1-33-21(31)13-8-17(20(27)28-11-13)19-9-12-7-16(5-6-18(12)34-19)30-22(32)29-15-4-2-3-14(10-15)23(24,25)26/h2-11H,1H3,(H2,27,28)(H2,29,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM363243 (6-amino-N-[dimethyl(oxido)- lambda4-sulfanylidene]...) Show SMILES Cc1ccc(F)c(NC(=O)Nc2ccc3sc(cc3c2)-c2cc(cnc2N)C(=O)N=S(C)(C)=O)c1 Show InChI InChI=1S/C24H22FN5O3S2/c1-13-4-6-18(25)19(8-13)29-24(32)28-16-5-7-20-14(9-16)11-21(34-20)17-10-15(12-27-22(17)26)23(31)30-35(2,3)33/h4-12H,1-3H3,(H2,26,27)(H2,28,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM363197 (6-amino-N-[dimethyl(oxido)- lambda4-sulfanylidene]...) Show SMILES Cc1cccc(NC(=O)Nc2ccc3sc(cc3c2)-c2cc(cnc2N)C(=O)N=S(C)(C)=O)c1 Show InChI InChI=1S/C24H23N5O3S2/c1-14-5-4-6-17(9-14)27-24(31)28-18-7-8-20-15(10-18)12-21(33-20)19-11-16(13-26-22(19)25)23(30)29-34(2,3)32/h4-13H,1-3H3,(H2,25,26)(H2,27,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM365351 (6-amino-N-[bis(3- hydroxypropyl)(oxido)-lambda4- s...) Show SMILES Cc1cccc(NC(=O)Nc2ccc3sc(cc3c2)-c2cc(cnc2N)C(=O)N=S(=O)(CCCO)CCCO)c1 Show InChI InChI=1S/C28H31N5O5S2/c1-18-5-2-6-21(13-18)31-28(37)32-22-7-8-24-19(14-22)16-25(39-24)23-15-20(17-30-26(23)29)27(36)33-40(38,11-3-9-34)12-4-10-35/h2,5-8,13-17,34-35H,3-4,9-12H2,1H3,(H2,29,30)(H2,31,32,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365351 (6-amino-N-[bis(3- hydroxypropyl)(oxido)-lambda4- s...) Show SMILES Cc1cccc(NC(=O)Nc2ccc3sc(cc3c2)-c2cc(cnc2N)C(=O)N=S(=O)(CCCO)CCCO)c1 Show InChI InChI=1S/C28H31N5O5S2/c1-18-5-2-6-21(13-18)31-28(37)32-22-7-8-24-19(14-22)16-25(39-24)23-15-20(17-30-26(23)29)27(36)33-40(38,11-3-9-34)12-4-10-35/h2,5-8,13-17,34-35H,3-4,9-12H2,1H3,(H2,29,30)(H2,31,32,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM365368 (US10633373, Example 73 | US10669265, Example 73 | ...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1ccc(NC(=O)Nc2cc(C)ccc2F)cc1 Show InChI InChI=1S/C21H19FN4O3/c1-12-3-8-17(22)18(9-12)26-21(28)25-15-6-4-13(5-7-15)16-10-14(20(27)29-2)11-24-19(16)23/h3-11H,1-2H3,(H2,23,24)(H2,25,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM364999 (US10633373, Example 16 | US10669265, Example 16 | ...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3ccc(F)cc3F)ccc2s1 Show InChI InChI=1S/C22H16F2N4O3S/c1-31-21(29)12-7-15(20(25)26-10-12)19-8-11-6-14(3-5-18(11)32-19)27-22(30)28-17-4-2-13(23)9-16(17)24/h2-10H,1H3,(H2,25,26)(H2,27,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365217 (1-{2-[2-amino-5-(4,4,5,5- tetramethyl-1,3,2- dioxa...) Show SMILES Cc1ccc(F)c(NC(=O)Nc2ccc3sc(cc3c2)-c2cc(cnc2N)B2OC(C)(C)C(C)(C)O2)c1 Show InChI InChI=1S/C27H28BFN4O3S/c1-15-6-8-20(29)21(10-15)33-25(34)32-18-7-9-22-16(11-18)12-23(37-22)19-13-17(14-31-24(19)30)28-35-26(2,3)27(4,5)36-28/h6-14H,1-5H3,(H2,30,31)(H2,32,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM365013 (1-{2-[2-amino-5-(4,4,5,5- tetramethyl-1,3,2- dioxa...) Show SMILES CC1(C)OB(OC1(C)C)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3cc(ccc3F)C(F)(F)F)ccc2s1 Show InChI InChI=1S/C27H25BF4N4O3S/c1-25(2)26(3,4)39-28(38-25)16-12-18(23(33)34-13-16)22-10-14-9-17(6-8-21(14)40-22)35-24(37)36-20-11-15(27(30,31)32)5-7-19(20)29/h5-13H,1-4H3,(H2,33,34)(H2,35,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM364997 (US10633373, Example 14 | US10669265, Example 14 | ...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3ccccc3F)ccc2s1 Show InChI InChI=1S/C22H17FN4O3S/c1-30-21(28)13-9-15(20(24)25-11-13)19-10-12-8-14(6-7-18(12)31-19)26-22(29)27-17-5-3-2-4-16(17)23/h2-11H,1H3,(H2,24,25)(H2,26,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM364990 (US10633373, Example 8 | US10669265, Example 8 | US...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3cc(ccc3F)C(F)(F)F)ccc2s1 Show InChI InChI=1S/C23H16F4N4O3S/c1-34-21(32)12-7-15(20(28)29-10-12)19-8-11-6-14(3-5-18(11)35-19)30-22(33)31-17-9-13(23(25,26)27)2-4-16(17)24/h2-10H,1H3,(H2,28,29)(H2,30,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM364986 (US10633373, Example 7 | US10669265, Example 7 | US...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3cccc(c3)C(F)(F)F)ccc2s1 Show InChI InChI=1S/C23H17F3N4O3S/c1-33-21(31)13-8-17(20(27)28-11-13)19-9-12-7-16(5-6-18(12)34-19)30-22(32)29-15-4-2-3-14(10-15)23(24,25)26/h2-11H,1H3,(H2,27,28)(H2,29,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM364996 (US10633373, Example 13 | US10669265, Example 13 | ...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3ccc(C)cc3)ccc2s1 Show InChI InChI=1S/C23H20N4O3S/c1-13-3-5-16(6-4-13)26-23(29)27-17-7-8-19-14(9-17)11-20(31-19)18-10-15(22(28)30-2)12-25-21(18)24/h3-12H,1-2H3,(H2,24,25)(H2,26,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM365015 (1-{2-[2-amino-5-(4,4,5,5- tetramethyl-1,3,2- dioxa...) Show SMILES CC1(C)OB(OC1(C)C)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3cccc(c3)C(F)(F)F)ccc2s1 Show InChI InChI=1S/C27H26BF3N4O3S/c1-25(2)26(3,4)38-28(37-25)17-13-20(23(32)33-14-17)22-11-15-10-19(8-9-21(15)39-22)35-24(36)34-18-7-5-6-16(12-18)27(29,30)31/h5-14H,1-4H3,(H2,32,33)(H2,34,35,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365367 (US10633373, Example 72 | US10669265, Example 72 | ...) Show SMILES COC(=O)CCCCS(=O)(CCCCC(=O)OC)=NC(=O)c1cnc(N)c(c1)-c1ccc(NC(=O)Nc2cccc(c2)C(F)(F)F)cc1 Show InChI InChI=1S/C32H36F3N5O7S/c1-46-27(41)10-3-5-16-48(45,17-6-4-11-28(42)47-2)40-30(43)22-18-26(29(36)37-20-22)21-12-14-24(15-13-21)38-31(44)39-25-9-7-8-23(19-25)32(33,34)35/h7-9,12-15,18-20H,3-6,10-11,16-17H2,1-2H3,(H2,36,37)(H2,38,39,44)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM365364 (6-amino-N-[bis(3- hydroxypropyl)(oxido)-lambda6- s...) Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2cc(cnc2N)C(=O)N=S(=O)(CCCO)CCCO)c1 Show InChI InChI=1S/C26H31N5O5S/c1-18-5-2-6-22(15-18)30-26(35)29-21-9-7-19(8-10-21)23-16-20(17-28-24(23)27)25(34)31-37(36,13-3-11-32)14-4-12-33/h2,5-10,15-17,32-33H,3-4,11-14H2,1H3,(H2,27,28)(H2,29,30,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM365353 (5-{5-[({[4-chloro-3- (trifluoromethyl)phenyl]amino...) Show SMILES CS(C)(=O)=NC(=O)c1cncc(c1)-c1cc2cc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)ccc2s1 Show InChI InChI=1S/C24H18ClF3N4O3S2/c1-37(2,35)32-22(33)15-7-14(11-29-12-15)21-9-13-8-16(4-6-20(13)36-21)30-23(34)31-17-3-5-19(25)18(10-17)24(26,27)28/h3-12H,1-2H3,(H2,30,31,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM365365 (US10633373, Example 70 | US10669265, Example 70 | ...) Show SMILES COC(=O)CCCCS(=O)(CCCCC(=O)OC)=NC(=O)c1cnc(N)c(c1)-c1ccc(NC(=O)Nc2cccc(C)c2)cc1 Show InChI InChI=1S/C32H39N5O7S/c1-22-9-8-10-26(19-22)36-32(41)35-25-15-13-23(14-16-25)27-20-24(21-34-30(27)33)31(40)37-45(42,17-6-4-11-28(38)43-2)18-7-5-12-29(39)44-3/h8-10,13-16,19-21H,4-7,11-12,17-18H2,1-3H3,(H2,33,34)(H2,35,36,41)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM364991 (US10633373, Example 9 | US10669265, Example 9 | US...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)ccc2s1 Show InChI InChI=1S/C23H16ClF3N4O3S/c1-34-21(32)12-7-15(20(28)29-10-12)19-8-11-6-13(3-5-18(11)35-19)30-22(33)31-14-2-4-17(24)16(9-14)23(25,26)27/h2-10H,1H3,(H2,28,29)(H2,30,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM364992 (US10633373, Example 10 | US10669265, Example 10 | ...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3cc(C)ccc3F)ccc2s1 Show InChI InChI=1S/C23H19FN4O3S/c1-12-3-5-17(24)18(7-12)28-23(30)27-15-4-6-19-13(8-15)10-20(32-19)16-9-14(22(29)31-2)11-26-21(16)25/h3-11H,1-2H3,(H2,25,26)(H2,27,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365348 (US10633373, Example 53 | US10669265, Example 53 | ...) Show SMILES COC(=O)CCCC[S@](C)(=O)=NC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3cccc(C)c3)ccc2s1 |r| Show InChI InChI=1S/C29H31N5O5S2/c1-18-7-6-8-21(13-18)32-29(37)33-22-10-11-24-19(14-22)16-25(40-24)23-15-20(17-31-27(23)30)28(36)34-41(3,38)12-5-4-9-26(35)39-2/h6-8,10-11,13-17H,4-5,9,12H2,1-3H3,(H2,30,31)(H2,32,33,37)/t41-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM365216 (1-{2-[2-amino-5-(4,4,5,5- tetramethyl-1,3,2- dioxa...) Show SMILES CC1(C)OB(OC1(C)C)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)ccc2s1 Show InChI InChI=1S/C27H25BClF3N4O3S/c1-25(2)26(3,4)39-28(38-25)15-11-18(23(33)34-13-15)22-10-14-9-16(6-8-21(14)40-22)35-24(37)36-17-5-7-20(29)19(12-17)27(30,31)32/h5-13H,1-4H3,(H2,33,34)(H2,35,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM364992 (US10633373, Example 10 | US10669265, Example 10 | ...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3cc(C)ccc3F)ccc2s1 Show InChI InChI=1S/C23H19FN4O3S/c1-12-3-5-17(24)18(7-12)28-23(30)27-15-4-6-19-13(8-15)10-20(32-19)16-9-14(22(29)31-2)11-26-21(16)25/h3-11H,1-2H3,(H2,25,26)(H2,27,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM365314 (6-amino-N-[dimethyl(oxido)- lambda4-sulfanylidene]...) Show SMILES Cc1ccoc1C(=O)Nc1ccc2sc(cc2c1)-c1cc(cnc1N)C(=O)N=S(C)(C)=O Show InChI InChI=1S/C22H20N4O4S2/c1-12-6-7-30-19(12)22(28)25-15-4-5-17-13(8-15)10-18(31-17)16-9-14(11-24-20(16)23)21(27)26-32(2,3)29/h4-11H,1-3H3,(H2,23,24)(H,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM363243 (6-amino-N-[dimethyl(oxido)- lambda4-sulfanylidene]...) Show SMILES Cc1ccc(F)c(NC(=O)Nc2ccc3sc(cc3c2)-c2cc(cnc2N)C(=O)N=S(C)(C)=O)c1 Show InChI InChI=1S/C24H22FN5O3S2/c1-13-4-6-18(25)19(8-13)29-24(32)28-16-5-7-20-14(9-16)11-21(34-20)17-10-15(12-27-22(17)26)23(31)30-35(2,3)33/h4-12H,1-3H3,(H2,26,27)(H2,28,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM363234 (6-amino-5-[5-({[(3-chloro-4- fluorophenyl)amino]ca...) Show SMILES CS(C)(=O)=NC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3ccc(F)c(Cl)c3)ccc2s1 Show InChI InChI=1S/C23H19ClFN5O3S2/c1-35(2,33)30-22(31)13-8-16(21(26)27-11-13)20-9-12-7-14(4-6-19(12)34-20)28-23(32)29-15-3-5-18(25)17(24)10-15/h3-11H,1-2H3,(H2,26,27)(H2,28,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365013 (1-{2-[2-amino-5-(4,4,5,5- tetramethyl-1,3,2- dioxa...) Show SMILES CC1(C)OB(OC1(C)C)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3cc(ccc3F)C(F)(F)F)ccc2s1 Show InChI InChI=1S/C27H25BF4N4O3S/c1-25(2)26(3,4)39-28(38-25)16-12-18(23(33)34-13-16)22-10-14-9-17(6-8-21(14)40-22)35-24(37)36-20-11-15(27(30,31)32)5-7-19(20)29/h5-13H,1-4H3,(H2,33,34)(H2,35,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365308 (1-{2-[2-amino-5-(4,4,5,5- tetramethyl-1,3,2- dioxa...) Show SMILES CCc1cccc(NC(=O)Nc2ccc3sc(cc3c2)-c2cc(cnc2N)B2OC(C)(C)C(C)(C)O2)c1 Show InChI InChI=1S/C28H31BN4O3S/c1-6-17-8-7-9-20(12-17)32-26(34)33-21-10-11-23-18(13-21)14-24(37-23)22-15-19(16-31-25(22)30)29-35-27(2,3)28(4,5)36-29/h7-16H,6H2,1-5H3,(H2,30,31)(H2,32,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM364994 (US10633373, Example 11 | US10669265, Example 11 | ...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3cccc(C)c3)ccc2s1 Show InChI InChI=1S/C23H20N4O3S/c1-13-4-3-5-16(8-13)26-23(29)27-17-6-7-19-14(9-17)11-20(31-19)18-10-15(22(28)30-2)12-25-21(18)24/h3-12H,1-2H3,(H2,24,25)(H2,26,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM364994 (US10633373, Example 11 | US10669265, Example 11 | ...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3cccc(C)c3)ccc2s1 Show InChI InChI=1S/C23H20N4O3S/c1-13-4-3-5-16(8-13)26-23(29)27-17-6-7-19-14(9-17)11-20(31-19)18-10-15(22(28)30-2)12-25-21(18)24/h3-12H,1-2H3,(H2,24,25)(H2,26,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM363197 (6-amino-N-[dimethyl(oxido)- lambda4-sulfanylidene]...) Show SMILES Cc1cccc(NC(=O)Nc2ccc3sc(cc3c2)-c2cc(cnc2N)C(=O)N=S(C)(C)=O)c1 Show InChI InChI=1S/C24H23N5O3S2/c1-14-5-4-6-17(9-14)27-24(31)28-18-7-8-20-15(10-18)12-21(33-20)19-11-16(13-26-22(19)25)23(30)29-34(2,3)32/h4-13H,1-3H3,(H2,25,26)(H2,27,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365309 (1-{2-[2-amino-5-(4,4,5,5- tetramethyl-1,3,2- dioxa...) Show SMILES Cc1cccc(NC(=O)Nc2ccc3sc(cc3c2)-c2cc(cnc2N)B2OC(C)(C)C(C)(C)O2)c1 Show InChI InChI=1S/C27H29BN4O3S/c1-16-7-6-8-19(11-16)31-25(33)32-20-9-10-22-17(12-20)13-23(36-22)21-14-18(15-30-24(21)29)28-34-26(2,3)27(4,5)35-28/h6-15H,1-5H3,(H2,29,30)(H2,31,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365216 (1-{2-[2-amino-5-(4,4,5,5- tetramethyl-1,3,2- dioxa...) Show SMILES CC1(C)OB(OC1(C)C)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)ccc2s1 Show InChI InChI=1S/C27H25BClF3N4O3S/c1-25(2)26(3,4)39-28(38-25)15-11-18(23(33)34-13-15)22-10-14-9-16(6-8-21(14)40-22)35-24(37)36-17-5-7-20(29)19(12-17)27(30,31)32/h5-13H,1-4H3,(H2,33,34)(H2,35,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM364995 (US10633373, Example 12 | US10669265, Example 12 | ...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3ccc(F)c(Cl)c3)ccc2s1 Show InChI InChI=1S/C22H16ClFN4O3S/c1-31-21(29)12-7-15(20(25)26-10-12)19-8-11-6-13(3-5-18(11)32-19)27-22(30)28-14-2-4-17(24)16(23)9-14/h2-10H,1H3,(H2,25,26)(H2,27,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM364980 (6-amino-5-{5-[({[4-chloro-3- (trifluoromethyl)phen...) Show SMILES CS(C)(=O)=NC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)ccc2s1 Show InChI InChI=1S/C24H19ClF3N5O3S2/c1-38(2,36)33-22(34)13-8-16(21(29)30-11-13)20-9-12-7-14(4-6-19(12)37-20)31-23(35)32-15-3-5-18(25)17(10-15)24(26,27)28/h3-11H,1-2H3,(H2,29,30)(H2,31,32,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365357 (1-{4-[2-amino-5-(4,4,5,5- tetramethyl-1,3,2- dioxa...) Show SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2cc(cnc2N)B2OC(C)(C)C(C)(C)O2)c1 Show InChI InChI=1S/C25H28BFN4O3/c1-15-6-11-20(27)21(12-15)31-23(32)30-18-9-7-16(8-10-18)19-13-17(14-29-22(19)28)26-33-24(2,3)25(4,5)34-26/h6-14H,1-5H3,(H2,28,29)(H2,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM364990 (US10633373, Example 8 | US10669265, Example 8 | US...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3cc(ccc3F)C(F)(F)F)ccc2s1 Show InChI InChI=1S/C23H16F4N4O3S/c1-34-21(32)12-7-15(20(28)29-10-12)19-8-11-6-14(3-5-18(11)35-19)30-22(33)31-17-9-13(23(25,26)27)2-4-16(17)24/h2-10H,1H3,(H2,28,29)(H2,30,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM365356 (US10633373, Example 61 | US10669265, Example 61 | ...) Show SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2cc(cnc2N)B(O)O)c1 Show InChI InChI=1S/C19H18BFN4O3/c1-11-2-7-16(21)17(8-11)25-19(26)24-14-5-3-12(4-6-14)15-9-13(20(27)28)10-23-18(15)22/h2-10,27-28H,1H3,(H2,22,23)(H2,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365338 (US10633373, Example 43 | US10669265, Example 43 | ...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)c3ccc(F)c(Cl)c3)ccc2s1 Show InChI InChI=1S/C22H15ClFN3O3S/c1-30-22(29)13-7-15(20(25)26-10-13)19-9-12-6-14(3-5-18(12)31-19)27-21(28)11-2-4-17(24)16(23)8-11/h2-10H,1H3,(H2,25,26)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365335 (US10633373, Example 40 | US10669265, Example 40 | ...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)c3cccc(C)c3)ccc2s1 Show InChI InChI=1S/C23H19N3O3S/c1-13-4-3-5-14(8-13)22(27)26-17-6-7-19-15(9-17)11-20(30-19)18-10-16(23(28)29-2)12-25-21(18)24/h3-12H,1-2H3,(H2,24,25)(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 123 total )  |  Next  |  Last  >>

Jump to: