Compile Data Set for Download or QSAR

Found 49 hits Enz. Inhib. hit(s) with all data for entry = 50001764   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50055366 ((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...) Show SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-2A expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366784 (CHEMBL4171084) Show SMILES NC(=O)c1cc2ccc(OC(F)(F)F)cc2n1-c1cccc(CCC(O)=O)c1 Show InChI InChI=1S/C19H15F3N2O4/c20-19(21,22)28-14-6-5-12-9-16(18(23)27)24(15(12)10-14)13-3-1-2-11(8-13)4-7-17(25)26/h1-3,5-6,8-10H,4,7H2,(H2,23,27)(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50055366 ((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...) Show SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366811 (CHEMBL4176544) Show SMILES NC(=O)c1cc2ccc(cc2n1-c1cccc(CCC(O)=O)c1)C(F)(F)F Show InChI InChI=1S/C19H15F3N2O3/c20-19(21,22)13-6-5-12-9-16(18(23)27)24(15(12)10-13)14-3-1-2-11(8-14)4-7-17(25)26/h1-3,5-6,8-10H,4,7H2,(H2,23,27)(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366983 (CHEMBL4160483) Show SMILES NC(=O)c1cc2ccc(OC(F)F)cc2n1-c1cccc(CCC(O)=O)c1 Show InChI InChI=1S/C19H16F2N2O4/c20-19(21)27-14-6-5-12-9-16(18(22)26)23(15(12)10-14)13-3-1-2-11(8-13)4-7-17(24)25/h1-3,5-6,8-10,19H,4,7H2,(H2,22,26)(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366807 (CHEMBL4172222) Show SMILES NC(=O)c1cc2ccc(Cl)cc2n1-c1cccc(CCC(O)=O)c1 Show InChI InChI=1S/C30H47N5O15/c1-11(2)5-4-6-16(39)33-20-23(43)21(41)14(47-29(20)50-28-19(32-12(3)37)22(42)18(31)15(10-36)48-28)9-13(38)26-24(44)25(45)27(49-26)35-8-7-17(40)34-30(35)46/h4,6-8,11,13-15,18-29,36,38,41-45H,5,9-10,31H2,1-3H3,(H,32,37)(H,33,39)(H,34,40,46)/b6-4+/t13?,14-,15-,18-,19-,20-,21+,22+,23-,24+,25-,26-,27-,28-,29+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366839 (CHEMBL4175583) Show SMILES NC(=O)c1cc2ccc(OCC(F)(F)F)cc2n1-c1cccc(CCC(O)=O)c1 Show InChI InChI=1S/C20H17F3N2O4/c21-20(22,23)11-29-15-6-5-13-9-17(19(24)28)25(16(13)10-15)14-3-1-2-12(8-14)4-7-18(26)27/h1-3,5-6,8-10H,4,7,11H2,(H2,24,28)(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Mus musculus)	BDBM50366784 (CHEMBL4171084) Show SMILES NC(=O)c1cc2ccc(OC(F)(F)F)cc2n1-c1cccc(CCC(O)=O)c1 Show InChI InChI=1S/C19H15F3N2O4/c20-19(21,22)28-14-6-5-12-9-16(18(23)27)24(15(12)10-14)13-3-1-2-11(8-13)4-7-17(25)26/h1-3,5-6,8-10H,4,7H2,(H2,23,27)(H,25,26)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of mouse sPLA2-10 using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate pretreated for 20 mins followed by substrate additio...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366840 (CHEMBL4174522) Show SMILES NC(=O)c1cc2ccc(cc2n1-c1cccc(CCC(O)=O)c1)C#N Show InChI InChI=1S/C19H15N3O3/c20-11-13-4-6-14-10-17(19(21)25)22(16(14)9-13)15-3-1-2-12(8-15)5-7-18(23)24/h1-4,6,8-10H,5,7H2,(H2,21,25)(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Phospholipase A2 group V (Homo sapiens (Human))	BDBM50055366 ((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...) Show SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	124	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-5 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate p...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50055366 ((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...) Show SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using HDL as substrate pretreated for 20 mins followed by substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366905 (CHEMBL4173359) Show SMILES NC(=O)c1cc2ccc(cc2n1-c1cccc(CCC(O)=O)c1)C1CC1 Show InChI InChI=1S/C21H20N2O3/c22-21(26)19-12-16-8-7-15(14-5-6-14)11-18(16)23(19)17-3-1-2-13(10-17)4-9-20(24)25/h1-3,7-8,10-12,14H,4-6,9H2,(H2,22,26)(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366889 (CHEMBL4175643) Show SMILES CCc1ccc2cc(C(N)=O)n(-c3cccc(CCC(O)=O)c3)c2c1 Show InChI InChI=1S/C20H22F2N4O/c1-19-9-8-14-13-5-3-12(20(21,22)18-23-25-26-24-18)10-11(13)2-4-15(14)16(19)6-7-17(19)27/h3,5,10,14-16H,2,4,6-9H2,1H3,(H,23,24,25,26)/t14-,15-,16+,19+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366876 (CHEMBL4171797) Show SMILES Cc1ccc2cc(C(N)=O)n(-c3cccc(CCC(O)=O)c3)c2c1 Show InChI InChI=1S/C19H18N2O3/c1-12-5-7-14-11-17(19(20)24)21(16(14)9-12)15-4-2-3-13(10-15)6-8-18(22)23/h2-5,7,9-11H,6,8H2,1H3,(H2,20,24)(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366968 (CHEMBL4161605) Show SMILES NC(=O)c1cc2ccc(F)cc2n1-c1cccc(CCC(O)=O)c1 Show InChI InChI=1S/C18H15FN2O3/c19-13-6-5-12-9-16(18(20)24)21(15(12)10-13)14-3-1-2-11(8-14)4-7-17(22)23/h1-3,5-6,8-10H,4,7H2,(H2,20,24)(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366784 (CHEMBL4171084) Show SMILES NC(=O)c1cc2ccc(OC(F)(F)F)cc2n1-c1cccc(CCC(O)=O)c1 Show InChI InChI=1S/C19H15F3N2O4/c20-19(21,22)28-14-6-5-12-9-16(18(23)27)24(15(12)10-14)13-3-1-2-11(8-13)4-7-17(25)26/h1-3,5-6,8-10H,4,7H2,(H2,23,27)(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using HDL as substrate pretreated for 20 mins followed by substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50366784 (CHEMBL4171084) Show SMILES NC(=O)c1cc2ccc(OC(F)(F)F)cc2n1-c1cccc(CCC(O)=O)c1 Show InChI InChI=1S/C19H15F3N2O4/c20-19(21,22)28-14-6-5-12-9-16(18(23)27)24(15(12)10-14)13-3-1-2-11(8-13)4-7-17(25)26/h1-3,5-6,8-10H,4,7H2,(H2,23,27)(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-2A expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366983 (CHEMBL4160483) Show SMILES NC(=O)c1cc2ccc(OC(F)F)cc2n1-c1cccc(CCC(O)=O)c1 Show InChI InChI=1S/C19H16F2N2O4/c20-19(21)27-14-6-5-12-9-16(18(22)26)23(15(12)10-14)13-3-1-2-11(8-13)4-7-17(24)25/h1-3,5-6,8-10,19H,4,7H2,(H2,22,26)(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using HDL as substrate pretreated for 20 mins followed by substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366811 (CHEMBL4176544) Show SMILES NC(=O)c1cc2ccc(cc2n1-c1cccc(CCC(O)=O)c1)C(F)(F)F Show InChI InChI=1S/C19H15F3N2O3/c20-19(21,22)13-6-5-12-9-16(18(23)27)24(15(12)10-13)14-3-1-2-11(8-14)4-7-17(25)26/h1-3,5-6,8-10H,4,7H2,(H2,23,27)(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using HDL as substrate pretreated for 20 mins followed by substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366970 (CHEMBL4160502) Show SMILES COc1ccc2cc(C(N)=O)n(-c3cccc(CCC(O)=O)c3)c2c1 Show InChI InChI=1S/C19H18N2O4/c1-25-15-7-6-13-10-17(19(20)24)21(16(13)11-15)14-4-2-3-12(9-14)5-8-18(22)23/h2-4,6-7,9-11H,5,8H2,1H3,(H2,20,24)(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366839 (CHEMBL4175583) Show SMILES NC(=O)c1cc2ccc(OCC(F)(F)F)cc2n1-c1cccc(CCC(O)=O)c1 Show InChI InChI=1S/C20H17F3N2O4/c21-20(22,23)11-29-15-6-5-13-9-17(19(24)28)25(16(13)10-15)14-3-1-2-12(8-14)4-7-18(26)27/h1-3,5-6,8-10H,4,7,11H2,(H2,24,28)(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using HDL as substrate pretreated for 20 mins followed by substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366965 (CHEMBL4159939) Show SMILES Cc1cccc2n(c(cc12)C(N)=O)-c1cccc(CCC(O)=O)c1 Show InChI InChI=1S/C19H18N2O3/c1-12-4-2-7-16-15(12)11-17(19(20)24)21(16)14-6-3-5-13(10-14)8-9-18(22)23/h2-7,10-11H,8-9H2,1H3,(H2,20,24)(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50366811 (CHEMBL4176544) Show SMILES NC(=O)c1cc2ccc(cc2n1-c1cccc(CCC(O)=O)c1)C(F)(F)F Show InChI InChI=1S/C19H15F3N2O3/c20-19(21,22)13-6-5-12-9-16(18(23)27)24(15(12)10-13)14-3-1-2-11(8-14)4-7-17(25)26/h1-3,5-6,8-10H,4,7H2,(H2,23,27)(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	890	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-2A expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366959 (CHEMBL4176269) Show SMILES NC(=O)c1cc2ccccc2n1-c1cccc(CCC(O)=O)c1 Show InChI InChI=1S/C18H16N2O3/c19-18(23)16-11-13-5-1-2-7-15(13)20(16)14-6-3-4-12(10-14)8-9-17(21)22/h1-7,10-11H,8-9H2,(H2,19,23)(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	990	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366840 (CHEMBL4174522) Show SMILES NC(=O)c1cc2ccc(cc2n1-c1cccc(CCC(O)=O)c1)C#N Show InChI InChI=1S/C19H15N3O3/c20-11-13-4-6-14-10-17(19(21)25)22(16(14)9-13)15-3-1-2-12(8-15)5-7-18(23)24/h1-4,6,8-10H,5,7H2,(H2,21,25)(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	990	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using HDL as substrate pretreated for 20 mins followed by substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366807 (CHEMBL4172222) Show SMILES NC(=O)c1cc2ccc(Cl)cc2n1-c1cccc(CCC(O)=O)c1 Show InChI InChI=1S/C30H47N5O15/c1-11(2)5-4-6-16(39)33-20-23(43)21(41)14(47-29(20)50-28-19(32-12(3)37)22(42)18(31)15(10-36)48-28)9-13(38)26-24(44)25(45)27(49-26)35-8-7-17(40)34-30(35)46/h4,6-8,11,13-15,18-29,36,38,41-45H,5,9-10,31H2,1-3H3,(H,32,37)(H,33,39)(H,34,40,46)/b6-4+/t13?,14-,15-,18-,19-,20-,21+,22+,23-,24+,25-,26-,27-,28-,29+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using HDL as substrate pretreated for 20 mins followed by substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366783 (CHEMBL4170085) Show SMILES Cc1cccc2cc(C(N)=O)n(-c3cccc(CCC(O)=O)c3)c12 Show InChI InChI=1S/C19H18N2O3/c1-12-4-2-6-14-11-16(19(20)24)21(18(12)14)15-7-3-5-13(10-15)8-9-17(22)23/h2-7,10-11H,8-9H2,1H3,(H2,20,24)(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366905 (CHEMBL4173359) Show SMILES NC(=O)c1cc2ccc(cc2n1-c1cccc(CCC(O)=O)c1)C1CC1 Show InChI InChI=1S/C21H20N2O3/c22-21(26)19-12-16-8-7-15(14-5-6-14)11-18(16)23(19)17-3-1-2-13(10-17)4-9-20(24)25/h1-3,7-8,10-12,14H,4-6,9H2,(H2,22,26)(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using HDL as substrate pretreated for 20 mins followed by substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Phospholipase A2 group V (Homo sapiens (Human))	BDBM50366784 (CHEMBL4171084) Show SMILES NC(=O)c1cc2ccc(OC(F)(F)F)cc2n1-c1cccc(CCC(O)=O)c1 Show InChI InChI=1S/C19H15F3N2O4/c20-19(21,22)28-14-6-5-12-9-16(18(23)27)24(15(12)10-14)13-3-1-2-11(8-13)4-7-17(25)26/h1-3,5-6,8-10H,4,7H2,(H2,23,27)(H,25,26)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	2.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-5 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate p...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50366905 (CHEMBL4173359) Show SMILES NC(=O)c1cc2ccc(cc2n1-c1cccc(CCC(O)=O)c1)C1CC1 Show InChI InChI=1S/C21H20N2O3/c22-21(26)19-12-16-8-7-15(14-5-6-14)11-18(16)23(19)17-3-1-2-13(10-17)4-9-20(24)25/h1-3,7-8,10-12,14H,4-6,9H2,(H2,22,26)(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-2A expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366967 (CHEMBL4168202) Show SMILES Cc1ccc2n(c(cc2c1)C(N)=O)-c1cccc(CCC(O)=O)c1 Show InChI InChI=1S/C19H18N2O3/c1-12-5-7-16-14(9-12)11-17(19(20)24)21(16)15-4-2-3-13(10-15)6-8-18(22)23/h2-5,7,9-11H,6,8H2,1H3,(H2,20,24)(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366971 (CHEMBL4163859) Show SMILES NC(=O)c1cc2ccc(CO)cc2n1-c1cccc(CCC(O)=O)c1 Show InChI InChI=1S/C19H18N2O4/c20-19(25)17-10-14-6-4-13(11-22)9-16(14)21(17)15-3-1-2-12(8-15)5-7-18(23)24/h1-4,6,8-10,22H,5,7,11H2,(H2,20,25)(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50366983 (CHEMBL4160483) Show SMILES NC(=O)c1cc2ccc(OC(F)F)cc2n1-c1cccc(CCC(O)=O)c1 Show InChI InChI=1S/C19H16F2N2O4/c20-19(21)27-14-6-5-12-9-16(18(22)26)23(15(12)10-14)13-3-1-2-11(8-13)4-7-17(24)25/h1-3,5-6,8-10,19H,4,7H2,(H2,22,26)(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-2A expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Phospholipase A2 group V (Homo sapiens (Human))	BDBM50366811 (CHEMBL4176544) Show SMILES NC(=O)c1cc2ccc(cc2n1-c1cccc(CCC(O)=O)c1)C(F)(F)F Show InChI InChI=1S/C19H15F3N2O3/c20-19(21,22)13-6-5-12-9-16(18(23)27)24(15(12)10-13)14-3-1-2-11(8-14)4-7-17(25)26/h1-3,5-6,8-10H,4,7H2,(H2,23,27)(H,25,26)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-5 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate p...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50366840 (CHEMBL4174522) Show SMILES NC(=O)c1cc2ccc(cc2n1-c1cccc(CCC(O)=O)c1)C#N Show InChI InChI=1S/C19H15N3O3/c20-11-13-4-6-14-10-17(19(21)25)22(16(14)9-13)15-3-1-2-12(8-15)5-7-18(23)24/h1-4,6,8-10H,5,7H2,(H2,21,25)(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-2A expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50366889 (CHEMBL4175643) Show SMILES CCc1ccc2cc(C(N)=O)n(-c3cccc(CCC(O)=O)c3)c2c1 Show InChI InChI=1S/C20H22F2N4O/c1-19-9-8-14-13-5-3-12(20(21,22)18-23-25-26-24-18)10-11(13)2-4-15(14)16(19)6-7-17(19)27/h3,5,10,14-16H,2,4,6-9H2,1H3,(H,23,24,25,26)/t14-,15-,16+,19+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-2A expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366984 (CHEMBL4172025) Show SMILES CS(=O)(=O)NC(=O)CCc1cccc(c1)-n1c(cc2ccccc12)C(N)=O Show InChI InChI=1S/C19H19N3O4S/c1-27(25,26)21-18(23)10-9-13-5-4-7-15(11-13)22-16-8-3-2-6-14(16)12-17(22)19(20)24/h2-8,11-12H,9-10H2,1H3,(H2,20,24)(H,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50366807 (CHEMBL4172222) Show SMILES NC(=O)c1cc2ccc(Cl)cc2n1-c1cccc(CCC(O)=O)c1 Show InChI InChI=1S/C30H47N5O15/c1-11(2)5-4-6-16(39)33-20-23(43)21(41)14(47-29(20)50-28-19(32-12(3)37)22(42)18(31)15(10-36)48-28)9-13(38)26-24(44)25(45)27(49-26)35-8-7-17(40)34-30(35)46/h4,6-8,11,13-15,18-29,36,38,41-45H,5,9-10,31H2,1-3H3,(H,32,37)(H,33,39)(H,34,40,46)/b6-4+/t13?,14-,15-,18-,19-,20-,21+,22+,23-,24+,25-,26-,27-,28-,29+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-2A expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366804 (CHEMBL4169491) Show SMILES NC(=O)c1cc2ccccc2n1-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C16H11F3N2O/c17-16(18,19)11-5-3-6-12(9-11)21-13-7-2-1-4-10(13)8-14(21)15(20)22/h1-9H,(H2,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366857 (CHEMBL4168275) Show SMILES NC(=O)c1cc2ccccc2n1-c1cccc(c1)C(=O)NCC(O)=O Show InChI InChI=1S/C18H15N3O4/c19-17(24)15-9-11-4-1-2-7-14(11)21(15)13-6-3-5-12(8-13)18(25)20-10-16(22)23/h1-9H,10H2,(H2,19,24)(H,20,25)(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Phospholipase A2 group V (Homo sapiens (Human))	BDBM50366905 (CHEMBL4173359) Show SMILES NC(=O)c1cc2ccc(cc2n1-c1cccc(CCC(O)=O)c1)C1CC1 Show InChI InChI=1S/C21H20N2O3/c22-21(26)19-12-16-8-7-15(14-5-6-14)11-18(16)23(19)17-3-1-2-13(10-17)4-9-20(24)25/h1-3,7-8,10-12,14H,4-6,9H2,(H2,22,26)(H,24,25)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-5 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate p...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50366839 (CHEMBL4175583) Show SMILES NC(=O)c1cc2ccc(OCC(F)(F)F)cc2n1-c1cccc(CCC(O)=O)c1 Show InChI InChI=1S/C20H17F3N2O4/c21-20(22,23)11-29-15-6-5-13-9-17(19(24)28)25(16(13)10-15)14-3-1-2-12(8-14)4-7-18(26)27/h1-3,5-6,8-10H,4,7,11H2,(H2,24,28)(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-2A expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366856 (CHEMBL4176688) Show SMILES NC(=O)c1cc2ccccc2n1-c1cccc(CC(O)=O)c1 Show InChI InChI=1S/C17H14N2O3/c18-17(22)15-10-12-5-1-2-7-14(12)19(15)13-6-3-4-11(8-13)9-16(20)21/h1-8,10H,9H2,(H2,18,22)(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366964 (CHEMBL4175476) Show SMILES NC(=O)c1cc2ccccc2n1Cc1cccc(c1)C(O)=O Show InChI InChI=1S/C17H14N2O3/c18-16(20)15-9-12-5-1-2-7-14(12)19(15)10-11-4-3-6-13(8-11)17(21)22/h1-9H,10H2,(H2,18,20)(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366960 (CHEMBL4168405) Show SMILES NC(=O)c1cc2ccccc2n1-c1cccc(\C=C\C(O)=O)c1 Show InChI InChI=1S/C18H14N2O3/c19-18(23)16-11-13-5-1-2-7-15(13)20(16)14-6-3-4-12(10-14)8-9-17(21)22/h1-11H,(H2,19,23)(H,21,22)/b9-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366963 (CHEMBL4160366) Show SMILES NC(=O)c1cc2ccccc2n1-c1cccc(OCC(O)=O)c1 Show InChI InChI=1S/C17H14N2O4/c18-17(22)15-8-11-4-1-2-7-14(11)19(15)12-5-3-6-13(9-12)23-10-16(20)21/h1-9H,10H2,(H2,18,22)(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.69E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366806 (CHEMBL4166071) Show SMILES NC(=O)c1cc2ccccc2n1-c1cccc(c1)C(O)=O Show InChI InChI=1S/C16H24N4O9/c17-4-9-12(24)13(25)15(28-9)29-10(5-18-6-21)8-3-7(22)14(27-8)20-2-1-11(23)19-16(20)26/h1-2,6-10,12-15,22,24-25H,3-5,17H2,(H,18,21)(H,19,23,26)/t7-,8+,9-,10+,12-,13-,14-,15+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.91E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366782 (CHEMBL4164836) Show SMILES NC(=O)CCc1cccc(c1)-n1c(cc2ccccc12)C(N)=O Show InChI InChI=1S/C18H17N3O2/c19-17(22)9-8-12-4-3-6-14(10-12)21-15-7-2-1-5-13(15)11-16(21)18(20)23/h1-7,10-11H,8-9H2,(H2,19,22)(H2,20,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50366921 (CHEMBL4161571) Show SMILES NC(=O)c1cc2ccccc2n1-c1ccccc1 Show InChI InChI=1S/C15H12N2O/c16-15(18)14-10-11-6-4-5-9-13(11)17(14)12-7-2-1-3-8-12/h1-10H,(H2,16,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...				ACS Med Chem Lett 9: 594-599 (2018) Article DOI: 10.1021/acsmedchemlett.7b00505 BindingDB Entry DOI: 10.7270/Q2Z60RMJ
					More data for this Ligand-Target Pair