Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protease (Human immunodeficiency virus 1 (HIV-1)) | BDBM50489369![]() (CHEMBL1232930 | GRL-0519) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | Article PubMed | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgia State University Curated by ChEMBL | Assay Description Inhibition of HIV-1 wildtype protease using Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 as substrate incubated for 5 mins prior to substrate addition mea... | J Med Chem 56: 1074-83 (2013) Article DOI: 10.1021/jm301519z BindingDB Entry DOI: 10.7270/Q2542RH4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HIV-1 protease (Human immunodeficiency virus) | BDBM50489369![]() (CHEMBL1232930 | GRL-0519) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | Article PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgia State University Curated by ChEMBL | Assay Description Inhibition of HIV-1 protease R8Q mutant using Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 as substrate incubated for 5 mins prior to substrate addition m... | J Med Chem 56: 1074-83 (2013) Article DOI: 10.1021/jm301519z BindingDB Entry DOI: 10.7270/Q2542RH4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HIV-1 protease (Human immunodeficiency virus) | BDBM50489369![]() (CHEMBL1232930 | GRL-0519) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | Article PubMed | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgia State University Curated by ChEMBL | Assay Description Inhibition of HIV-1 protease V82A mutant using Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 as substrate incubated for 5 mins prior to substrate addition ... | J Med Chem 56: 1074-83 (2013) Article DOI: 10.1021/jm301519z BindingDB Entry DOI: 10.7270/Q2542RH4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HIV-1 protease (Human immunodeficiency virus) | BDBM50489369![]() (CHEMBL1232930 | GRL-0519) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | Article PubMed | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgia State University Curated by ChEMBL | Assay Description Inhibition of HIV-1 protease I54M mutant using Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 as substrate incubated for 5 mins prior to substrate addition ... | J Med Chem 56: 1074-83 (2013) Article DOI: 10.1021/jm301519z BindingDB Entry DOI: 10.7270/Q2542RH4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HIV-1 protease (Human immunodeficiency virus) | BDBM50489369![]() (CHEMBL1232930 | GRL-0519) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | Article PubMed | 8.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgia State University Curated by ChEMBL | Assay Description Inhibition of HIV-1 protease D30N mutant using Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 as substrate incubated for 5 mins prior to substrate addition ... | J Med Chem 56: 1074-83 (2013) Article DOI: 10.1021/jm301519z BindingDB Entry DOI: 10.7270/Q2542RH4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HIV-1 protease (Human immunodeficiency virus) | BDBM50489369![]() (CHEMBL1232930 | GRL-0519) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | Article PubMed | 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgia State University Curated by ChEMBL | Assay Description Inhibition of HIV-1 protease I50V mutant using Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 as substrate incubated for 5 mins prior to substrate addition ... | J Med Chem 56: 1074-83 (2013) Article DOI: 10.1021/jm301519z BindingDB Entry DOI: 10.7270/Q2542RH4 | |||||||||||
More data for this Ligand-Target Pair |