Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50037795![]() (CHEMBL120885 | Furan-2-carboxylic acid hydroxy-[1-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay | J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50037791![]() (4-(Hydroxy-{1-[2-(3,4,5-trimethoxy-phenyl)-benzofu...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay | J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50037807![]() (CHEMBL331626 | N-[1-(2-Butyl-benzofuran-5-yl)-ethy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay | J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50037805![]() (CHEMBL121025 | N-hydroxy-N-[1-[2-(3,4,5-trimethoxy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay | J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50037803![]() (4-{[1-(2-Butyl-benzofuran-5-yl)-ethyl]-hydroxy-car...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay | J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50037792![]() (CHEMBL122955 | N-Hydroxy-N-[1-(2-phenyl-benzofuran...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay | J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50037793![]() (4-{Hydroxy-[1-(2-phenyl-benzofuran-5-yl)-ethyl]-ca...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay | J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50037788![]() (CHEMBL421255 | N-Hydroxy-N-{1-[2-(6-methoxy-naphth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay | J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50037801![]() (4-{[1-(2-Decyl-benzofuran-5-yl)-ethyl]-hydroxy-car...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay | J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50037796![]() (Acetic acid {hydroxy-[1-(2-phenyl-benzofuran-5-yl)...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay | J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50037789![]() (CHEMBL332395 | N-Hydroxy-2-methoxy-N-[1-(2-phenyl-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay | J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50037797![]() (CHEMBL123396 | N-Hydroxy-3,4-dimethoxy-N-[1-(2-phe...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay | J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50037806![]() (CHEMBL123177 | Thiophene-2-carboxylic acid hydroxy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay | J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50037794![]() (CHEMBL331060 | N-Hydroxy-N-{1-[2-(3,4,5-trimethoxy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay | J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50022683![]() (CHEMBL418304 | N-[1-(4-Benzyloxy-phenyl)-ethyl]-N-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay | J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50000541![]() ((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay | J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50037799![]() (CHEMBL123649 | N-Hydroxy-N-[1-(4-phenethyloxy-phen...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay | J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50037790![]() (CHEMBL331881 | N-[1-(2-Decyl-benzofuran-5-yl)-ethy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay | J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50037798![]() (CHEMBL121390 | N-hydroxy-N-[1-(2-phinyl-5-benzofur...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay | J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50037787![]() (CHEMBL332814 | N-Hydroxy-N-[1-(2-phenyl-benzofuran...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 490 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay | J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50022697![]() (CHEMBL62114 | N-Hydroxy-N-{1-[4-(1-phenyl-ethoxy)-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay | J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50037804![]() (2,N-Dihydroxy-N-[1-(2-phenyl-benzofuran-5-yl)-ethy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay | J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50037802![]() (CHEMBL120107 | N-Hydroxy-2,6-dimethoxy-N-[1-(2-phe...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay | J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50037800![]() (CHEMBL121555 | N-Hydroxy-N-[1-(2-phenyl-benzofuran...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay | J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2 | |||||||||||
More data for this Ligand-Target Pair |