Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fibroblast growth factor receptor 3 (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human wild-type N-terminal GST-His6-fused FGFR3 C-terminal domain (R397 to T806 residues) expressed in Sf9 insect cells usi... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human N-terminal GST-His6-fused TRKB C-terminal domain (V526 to G838 residues) expressed in Sf9 insect cells using Poly(Glu... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
SRSF protein kinase 1 (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human full-length N-terminal GST-His6-fused SRPK1 (M1 to S655 residues) expressed in Sf9 insect cells using RS-peptide as s... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor tyrosine-protein kinase erbB-4 (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human N-terminal GST-His6-fused ERBB4 C-terminal domain (R676 to V1307 residues) expressed in Sf9 cells using Poly(Glu:Tyr)... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human full-length N-terminal GST-His6-fused SRC (M1 to L536 residues) expressed in Sf9 insect cells using Poly(Glu:Tyr)4:1 ... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human wild-type N-terminal GST-His6-fused EGFR C-terminal domain (H672 to A1210) expressed in Sf9 insect cells using Poly(G... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 4 (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human N-terminal GST-His6-fused FGFR4 (R391 to T802 residues) expressed in baculovirus infected Sf9 cells using Poly(Glu:Ty... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human N-terminal His6-fused PDK1 (M1 to M460 residues) expressed in Sf9 insect cells using tetra(LRRWSLG) peptide as substr... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human wild-type N-terminal GST-His6-fused KIT C-terminal domain (T544 to V976 residues) expressed in Sf9 insect cells using... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 1 (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human wild-type N-terminal GST-His6-fused FGFR1 C-terminal domain (G400 to R820 residues) expressed in Sf9 insect cells usi... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein kinase CLK1 (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human full-length N-terminal GST-His6-fused CLK1 (M1 to I484 residues) expressed in Sf9 cells using RS-peptide as substrate... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human wild-type N-terminal GST-His6-fused TRKA C-terminal domain (G443 to G796 residues) expressed in Sf9 insect cells usin... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 10 (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human MAP3K10 measured after 60 mins in presence of [gamma-33P]-ATP by scintillation counting method | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-beta serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human N-terminal GST-His6-fused AKT2 C-terminal domain (A107 to E481 residues) expressed in Sf9 insect cells using GSK3(14-... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 2 (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human N-terminal GST-His6-fused FGFR2 C-terminal domain (R400 to T822 residues) expressed in Sf9 insect cells using TRK-C d... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human wild-type N-terminal GST-His6-fused ERBB2 C-terminal domain (Q679 to V1255 residues) expressed in Sf9 insect cells us... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human N-terminal GST-fused VEGFR2 C-terminal domain (D807 to V1356 residues) expressed in Sf9 insect cells using Poly(Glu:T... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 1 (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human ROCK1 measured after 60 mins in presence of [gamma-33P]-ATP by scintillation counting method | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human N-terminal GST-tagged VEGFR1 C-terminal domain (K784 to I1338 residues) expressed in Sf9 insect cells using Poly(Glu:... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor alpha (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human wild-type N-terminal GST-His6-fused PDGFR-alpha C-terminal domain (Q551 to L1089 residues) expressed in Sf9 insect ce... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human wild-type N-terminal GST-His6-fused MET C-terminal domain (K956 to S1390 residues) expressed in Sf9 insect cells usin... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 15 (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human N-terminal 4xFLAG-tagged/C-terminal His8-fused ERK7 N-terminal domain (M1 to R354 residues) expressed in Sf9 insect c... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 3 (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human full-length N-terminal GST-His6 fused ERK1 (M1 to P379 residues) expressed in Escherichia coli using RBER-CHKtide as ... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human N-terminal 4xFLAG-tagged/C-terminal His8 fused MAP3K1 C-terminal domain (M1193 to W1512 residues) expressed in Sf9 in... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 1 (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human full-length untagged ERK2 (M1 to S360 residues) expressed in Escherichia coli using recombinant ELK1 as substrate mea... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human wild-type N-terminal GST-His6-fused ABL1 internal domain (P118 to S535 residues) expressed in Sf9 insect cells using ... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity mitogen-activated protein kinase kinase 2 (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human MEK2 measured after 60 mins in presence of [gamma-33P]-ATP by scintillation counting method | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human CHK2 measured after 60 mins in presence of [gamma-33P]-ATP by scintillation counting method | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Wee1-like protein kinase (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human N-terminal GST-His6-fused WEE1 C-terminal domain (Q36 to Y432 residues) expressed in Sf9 cells using Poly(Ala,Glu,Lys... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor beta (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human N-terminal GST-His6-fused PDGFR-beta C-terminal domain (R561 to L1106 residues) expressed in Sf9 insect cells using P... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human full-length untagged p38-alpha (M1 to S360 residues) expressed in Escherichia coli cells using recombinant ATF2 as su... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 7 (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human N-terminal FLAG-tagged/C-terminal His8 fused ERK5 internal fragment domain (L5 to Q397 residues) expressed in Sf9 ins... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase II subunit alpha' (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human full-length N-terminal GST-His6-fused CK2-alpha2 (M1 to R350 residues) expressed in Sf9 insect cells using casein as ... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Focal adhesion kinase 1 (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human N-terminal GST-fused FAK (2 to 1052 residues) expressed in Sf9 insect cells using Poly(Glu/Tyr)4:1 as substrate measu... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 3 (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human N-terminal GST-His6 fused VEGFR3 C-terminal domain (N799 to R1298 residues) expressed in baculovirus infected Sf9 ins... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 9 (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human MAP3K9 measured after 60 mins in presence of [gamma-33P]-ATP by scintillation counting method | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity mitogen-activated protein kinase kinase 1 (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human wild-type full-length MEK1 (M1 to V393 residues) expressed in Sf9 insect cells using ERK2-K54R as substrate measured ... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-beta serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human full-length N-terminal GST-His6-fused AKT2 (M1 to E481 residues) expressed in Sf9 insect cells using GSK3-derived pep... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase II subunit alpha (Homo sapiens (Human)) | BDBM50510133![]() (CHEMBL4446681) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human full-length N-terminal GST-fused CK2-alpha1 (M1 to Q391 residues) expressed in Sf9 insect cells using casein as subst... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair |