Compile Data Set for Download or QSAR

Found 43 hits Enz. Inhib. hit(s) with all data for entry = 50007562   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50399540 (FORETINIB | US10464902, Foretinib | US10882853, Co...) Show SMILES COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCOCC1 Show InChI InChI=1S/C34H34F2N4O6/c1-43-30-20-25-27(21-31(30)45-16-2-13-40-14-17-44-18-15-40)37-12-9-28(25)46-29-8-7-24(19-26(29)36)39-33(42)34(10-11-34)32(41)38-23-5-3-22(35)4-6-23/h3-9,12,19-21H,2,10-11,13-18H2,1H3,(H,38,41)(H,39,42)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of KDR (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50399540 (FORETINIB | US10464902, Foretinib | US10882853, Co...) Show SMILES COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCOCC1 Show InChI InChI=1S/C34H34F2N4O6/c1-43-30-20-25-27(21-31(30)45-16-2-13-40-14-17-44-18-15-40)37-12-9-28(25)46-29-8-7-24(19-26(29)36)39-33(42)34(10-11-34)32(41)38-23-5-3-22(35)4-6-23/h3-9,12,19-21H,2,10-11,13-18H2,1H3,(H,38,41)(H,39,42)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair				3D Structure (crystal)
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50510569 (CHEMBL4533153) Show SMILES COc1cc2c(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C31H32F2N4O6S/c1-41-29-18-24-26(19-30(29)42-16-4-15-37-13-2-3-14-37)34-12-11-27(24)43-28-10-9-23(17-25(28)33)35-31(38)36-44(39,40)20-21-5-7-22(32)8-6-21/h5-12,17-19H,2-4,13-16,20H2,1H3,(H2,35,36,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Macrophage-stimulating protein receptor (Homo sapiens (Human))	BDBM50399540 (FORETINIB | US10464902, Foretinib | US10882853, Co...) Show SMILES COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCOCC1 Show InChI InChI=1S/C34H34F2N4O6/c1-43-30-20-25-27(21-31(30)45-16-2-13-40-14-17-44-18-15-40)37-12-9-28(25)46-29-8-7-24(19-26(29)36)39-33(42)34(10-11-34)32(41)38-23-5-3-22(35)4-6-23/h3-9,12,19-21H,2,10-11,13-18H2,1H3,(H,38,41)(H,39,42)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of RON (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50399540 (FORETINIB | US10464902, Foretinib | US10882853, Co...) Show SMILES COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCOCC1 Show InChI InChI=1S/C34H34F2N4O6/c1-43-30-20-25-27(21-31(30)45-16-2-13-40-14-17-44-18-15-40)37-12-9-28(25)46-29-8-7-24(19-26(29)36)39-33(42)34(10-11-34)32(41)38-23-5-3-22(35)4-6-23/h3-9,12,19-21H,2,10-11,13-18H2,1H3,(H,38,41)(H,39,42)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of PDGFRalpha (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50510573 (CHEMBL4535560) Show SMILES COc1cc2c(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCOCC1 Show InChI InChI=1S/C31H32F2N4O7S/c1-41-29-18-24-26(19-30(29)43-14-2-11-37-12-15-42-16-13-37)34-10-9-27(24)44-28-8-7-23(17-25(28)33)35-31(38)36-45(39,40)20-21-3-5-22(32)6-4-21/h3-10,17-19H,2,11-16,20H2,1H3,(H2,35,36,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50399540 (FORETINIB | US10464902, Foretinib | US10882853, Co...) Show SMILES COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCOCC1 Show InChI InChI=1S/C34H34F2N4O6/c1-43-30-20-25-27(21-31(30)45-16-2-13-40-14-17-44-18-15-40)37-12-9-28(25)46-29-8-7-24(19-26(29)36)39-33(42)34(10-11-34)32(41)38-23-5-3-22(35)4-6-23/h3-9,12,19-21H,2,10-11,13-18H2,1H3,(H,38,41)(H,39,42)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of FLT3 (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50510571 (CHEMBL4575176) Show SMILES COc1cc2c(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCCCC1 Show InChI InChI=1S/C32H34F2N4O6S/c1-42-30-19-25-27(20-31(30)43-17-5-16-38-14-3-2-4-15-38)35-13-12-28(25)44-29-11-10-24(18-26(29)34)36-32(39)37-45(40,41)21-22-6-8-23(33)9-7-22/h6-13,18-20H,2-5,14-17,21H2,1H3,(H2,36,37,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50399540 (FORETINIB | US10464902, Foretinib | US10882853, Co...) Show SMILES COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCOCC1 Show InChI InChI=1S/C34H34F2N4O6/c1-43-30-20-25-27(21-31(30)45-16-2-13-40-14-17-44-18-15-40)37-12-9-28(25)46-29-8-7-24(19-26(29)36)39-33(42)34(10-11-34)32(41)38-23-5-3-22(35)4-6-23/h3-9,12,19-21H,2,10-11,13-18H2,1H3,(H,38,41)(H,39,42)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of c-Kit (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50399540 (FORETINIB | US10464902, Foretinib | US10882853, Co...) Show SMILES COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCOCC1 Show InChI InChI=1S/C34H34F2N4O6/c1-43-30-20-25-27(21-31(30)45-16-2-13-40-14-17-44-18-15-40)37-12-9-28(25)46-29-8-7-24(19-26(29)36)39-33(42)34(10-11-34)32(41)38-23-5-3-22(35)4-6-23/h3-9,12,19-21H,2,10-11,13-18H2,1H3,(H,38,41)(H,39,42)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of FLT1 (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50399540 (FORETINIB | US10464902, Foretinib | US10882853, Co...) Show SMILES COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCOCC1 Show InChI InChI=1S/C34H34F2N4O6/c1-43-30-20-25-27(21-31(30)45-16-2-13-40-14-17-44-18-15-40)37-12-9-28(25)46-29-8-7-24(19-26(29)36)39-33(42)34(10-11-34)32(41)38-23-5-3-22(35)4-6-23/h3-9,12,19-21H,2,10-11,13-18H2,1H3,(H,38,41)(H,39,42)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50510581 (CHEMBL4576201) Show SMILES COc1cc2c(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccccc4)cc3F)ccnc2cc1OCCCN1CCCCC1 Show InChI InChI=1S/C32H35FN4O6S/c1-41-30-20-25-27(21-31(30)42-18-8-17-37-15-6-3-7-16-37)34-14-13-28(25)43-29-12-11-24(19-26(29)33)35-32(38)36-44(39,40)22-23-9-4-2-5-10-23/h2,4-5,9-14,19-21H,3,6-8,15-18,22H2,1H3,(H2,35,36,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.90	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50510570 (CHEMBL4519213) Show SMILES COc1cc2c(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccccc4)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C31H33FN4O6S/c1-40-29-19-24-26(20-30(29)41-17-7-16-36-14-5-6-15-36)33-13-12-27(24)42-28-11-10-23(18-25(28)32)34-31(37)35-43(38,39)21-22-8-3-2-4-9-22/h2-4,8-13,18-20H,5-7,14-17,21H2,1H3,(H2,34,35,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50510567 (CHEMBL4560292) Show SMILES COc1cc2c(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccccc4)cc3F)ccnc2cc1OCCCN1CCOCC1 Show InChI InChI=1S/C31H33FN4O7S/c1-40-29-19-24-26(20-30(29)42-15-5-12-36-13-16-41-17-14-36)33-11-10-27(24)43-28-9-8-23(18-25(28)32)34-31(37)35-44(38,39)21-22-6-3-2-4-7-22/h2-4,6-11,18-20H,5,12-17,21H2,1H3,(H2,34,35,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50510584 (CHEMBL4589505) Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(F)cc4)cc3F)c2cc1OC Show InChI InChI=1S/C25H21F2N3O6S/c1-34-23-12-18-20(13-24(23)35-2)28-10-9-21(18)36-22-8-7-17(11-19(22)27)29-25(31)30-37(32,33)14-15-3-5-16(26)6-4-15/h3-13H,14H2,1-2H3,(H2,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50510585 (CHEMBL4435665) Show SMILES COc1cc2c(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(C)cc4)cc3F)ccnc2cc1OCCCN1CCCCC1 Show InChI InChI=1S/C33H37FN4O6S/c1-23-7-9-24(10-8-23)22-45(40,41)37-33(39)36-25-11-12-30(27(34)19-25)44-29-13-14-35-28-21-32(31(42-2)20-26(28)29)43-18-6-17-38-15-4-3-5-16-38/h7-14,19-21H,3-6,15-18,22H2,1-2H3,(H2,36,37,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50510579 (CHEMBL4535496) Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)NS(=O)(=O)Cc4cccc(F)c4)cc3F)c2cc1OC Show InChI InChI=1S/C25H21F2N3O6S/c1-34-23-12-18-20(13-24(23)35-2)28-9-8-21(18)36-22-7-6-17(11-19(22)27)29-25(31)30-37(32,33)14-15-4-3-5-16(26)10-15/h3-13H,14H2,1-2H3,(H2,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50510572 (CHEMBL4518545) Show SMILES COc1cc2c(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(C)cc4)cc3F)ccnc2cc1OCCCN1CCOCC1 Show InChI InChI=1S/C32H35FN4O7S/c1-22-4-6-23(7-5-22)21-45(39,40)36-32(38)35-24-8-9-29(26(33)18-24)44-28-10-11-34-27-20-31(30(41-2)19-25(27)28)43-15-3-12-37-13-16-42-17-14-37/h4-11,18-20H,3,12-17,21H2,1-2H3,(H2,35,36,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50510586 (CHEMBL4462710) Show SMILES CCCCOc1cc2nccc(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(F)cc4)cc3F)c2cc1OC Show InChI InChI=1S/C28H27F2N3O6S/c1-3-4-13-38-27-16-23-21(15-26(27)37-2)24(11-12-31-23)39-25-10-9-20(14-22(25)30)32-28(34)33-40(35,36)17-18-5-7-19(29)8-6-18/h5-12,14-16H,3-4,13,17H2,1-2H3,(H2,32,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50510583 (CHEMBL4448719) Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(Cl)cc4)cc3F)c2cc1OC Show InChI InChI=1S/C25H21ClFN3O6S/c1-34-23-12-18-20(13-24(23)35-2)28-10-9-21(18)36-22-8-7-17(11-19(22)27)29-25(31)30-37(32,33)14-15-3-5-16(26)6-4-15/h3-13H,14H2,1-2H3,(H2,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50510580 (CHEMBL4555029) Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(F)cc4)cc3)c2cc1OC Show InChI InChI=1S/C25H22FN3O6S/c1-33-23-13-20-21(14-24(23)34-2)27-12-11-22(20)35-19-9-7-18(8-10-19)28-25(30)29-36(31,32)15-16-3-5-17(26)6-4-16/h3-14H,15H2,1-2H3,(H2,28,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50510568 (CHEMBL4578065) Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccccc4F)cc3F)c2cc1OC Show InChI InChI=1S/C25H21F2N3O6S/c1-34-23-12-17-20(13-24(23)35-2)28-10-9-21(17)36-22-8-7-16(11-19(22)27)29-25(31)30-37(32,33)14-15-5-3-4-6-18(15)26/h3-13H,14H2,1-2H3,(H2,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50510574 (CHEMBL4531059) Show SMILES CCCCOc1cc2nccc(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccccc4)cc3F)c2cc1OC Show InChI InChI=1S/C28H28FN3O6S/c1-3-4-14-37-27-17-23-21(16-26(27)36-2)24(12-13-30-23)38-25-11-10-20(15-22(25)29)31-28(33)32-39(34,35)18-19-8-6-5-7-9-19/h5-13,15-17H,3-4,14,18H2,1-2H3,(H2,31,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50510589 (CHEMBL4447563) Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccccc4)cc3F)c2cc1OC Show InChI InChI=1S/C25H22FN3O6S/c1-33-23-13-18-20(14-24(23)34-2)27-11-10-21(18)35-22-9-8-17(12-19(22)26)28-25(30)29-36(31,32)15-16-6-4-3-5-7-16/h3-14H,15H2,1-2H3,(H2,28,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50510582 (CHEMBL4537474) Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(Cl)cc4Cl)cc3F)c2cc1OC Show InChI InChI=1S/C25H20Cl2FN3O6S/c1-35-23-11-17-20(12-24(23)36-2)29-8-7-21(17)37-22-6-5-16(10-19(22)28)30-25(32)31-38(33,34)13-14-3-4-15(26)9-18(14)27/h3-12H,13H2,1-2H3,(H2,30,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50510587 (CHEMBL4520218) Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)NS(=O)(=O)Cc4cccc(C)c4)cc3F)c2cc1OC Show InChI InChI=1S/C26H24FN3O6S/c1-16-5-4-6-17(11-16)15-37(32,33)30-26(31)29-18-7-8-23(20(27)12-18)36-22-9-10-28-21-14-25(35-3)24(34-2)13-19(21)22/h4-14H,15H2,1-3H3,(H2,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50510577 (CHEMBL4469910) Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccccc4C)cc3F)c2cc1OC Show InChI InChI=1S/C26H24FN3O6S/c1-16-6-4-5-7-17(16)15-37(32,33)30-26(31)29-18-8-9-23(20(27)12-18)36-22-10-11-28-21-14-25(35-3)24(34-2)13-19(21)22/h4-14H,15H2,1-3H3,(H2,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50510588 (CHEMBL4535170) Show SMILES CCCCOc1cc2nccc(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(C)cc4)cc3F)c2cc1OC Show InChI InChI=1S/C29H30FN3O6S/c1-4-5-14-38-28-17-24-22(16-27(28)37-3)25(12-13-31-24)39-26-11-10-21(15-23(26)30)32-29(34)33-40(35,36)18-20-8-6-19(2)7-9-20/h6-13,15-17H,4-5,14,18H2,1-3H3,(H2,32,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50510576 (CHEMBL4542694) Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(Br)cc4)cc3F)c2cc1OC Show InChI InChI=1S/C25H21BrFN3O6S/c1-34-23-12-18-20(13-24(23)35-2)28-10-9-21(18)36-22-8-7-17(11-19(22)27)29-25(31)30-37(32,33)14-15-3-5-16(26)6-4-15/h3-13H,14H2,1-2H3,(H2,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50510590 (CHEMBL4545574) Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccccc4)cc3)c2cc1OC Show InChI InChI=1S/C25H23N3O6S/c1-32-23-14-20-21(15-24(23)33-2)26-13-12-22(20)34-19-10-8-18(9-11-19)27-25(29)28-35(30,31)16-17-6-4-3-5-7-17/h3-15H,16H2,1-2H3,(H2,27,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50510578 (CHEMBL4515605) Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(C)cc4)cc3F)c2cc1OC Show InChI InChI=1S/C26H24FN3O6S/c1-16-4-6-17(7-5-16)15-37(32,33)30-26(31)29-18-8-9-23(20(27)12-18)36-22-10-11-28-21-14-25(35-3)24(34-2)13-19(21)22/h4-14H,15H2,1-3H3,(H2,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50510575 (CHEMBL4514742) Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(cc4)C(F)(F)F)cc3F)c2cc1OC Show InChI InChI=1S/C26H21F4N3O6S/c1-37-23-12-18-20(13-24(23)38-2)31-10-9-21(18)39-22-8-7-17(11-19(22)27)32-25(34)33-40(35,36)14-15-3-5-16(6-4-15)26(28,29)30/h3-13H,14H2,1-2H3,(H2,32,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50510569 (CHEMBL4533153) Show SMILES COc1cc2c(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C31H32F2N4O6S/c1-41-29-18-24-26(19-30(29)42-16-4-15-37-13-2-3-14-37)34-12-11-27(24)43-28-10-9-23(17-25(28)33)35-31(38)36-44(39,40)20-21-5-7-22(32)8-6-21/h5-12,17-19H,2-4,13-16,20H2,1H3,(H2,35,36,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of KDR (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50510569 (CHEMBL4533153) Show SMILES COc1cc2c(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C31H32F2N4O6S/c1-41-29-18-24-26(19-30(29)42-16-4-15-37-13-2-3-14-37)34-12-11-27(24)43-28-10-9-23(17-25(28)33)35-31(38)36-44(39,40)20-21-5-7-22(32)8-6-21/h5-12,17-19H,2-4,13-16,20H2,1H3,(H2,35,36,38)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	242	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of PDGFRalpha (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50510569 (CHEMBL4533153) Show SMILES COc1cc2c(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C31H32F2N4O6S/c1-41-29-18-24-26(19-30(29)42-16-4-15-37-13-2-3-14-37)34-12-11-27(24)43-28-10-9-23(17-25(28)33)35-31(38)36-44(39,40)20-21-5-7-22(32)8-6-21/h5-12,17-19H,2-4,13-16,20H2,1H3,(H2,35,36,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	356	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Macrophage-stimulating protein receptor (Homo sapiens (Human))	BDBM50510569 (CHEMBL4533153) Show SMILES COc1cc2c(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C31H32F2N4O6S/c1-41-29-18-24-26(19-30(29)42-16-4-15-37-13-2-3-14-37)34-12-11-27(24)43-28-10-9-23(17-25(28)33)35-31(38)36-44(39,40)20-21-5-7-22(32)8-6-21/h5-12,17-19H,2-4,13-16,20H2,1H3,(H2,35,36,38)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	375	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of RON (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50510569 (CHEMBL4533153) Show SMILES COc1cc2c(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C31H32F2N4O6S/c1-41-29-18-24-26(19-30(29)42-16-4-15-37-13-2-3-14-37)34-12-11-27(24)43-28-10-9-23(17-25(28)33)35-31(38)36-44(39,40)20-21-5-7-22(32)8-6-21/h5-12,17-19H,2-4,13-16,20H2,1H3,(H2,35,36,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of c-Kit (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50510569 (CHEMBL4533153) Show SMILES COc1cc2c(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C31H32F2N4O6S/c1-41-29-18-24-26(19-30(29)42-16-4-15-37-13-2-3-14-37)34-12-11-27(24)43-28-10-9-23(17-25(28)33)35-31(38)36-44(39,40)20-21-5-7-22(32)8-6-21/h5-12,17-19H,2-4,13-16,20H2,1H3,(H2,35,36,38)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of FLT3 (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50510569 (CHEMBL4533153) Show SMILES COc1cc2c(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C31H32F2N4O6S/c1-41-29-18-24-26(19-30(29)42-16-4-15-37-13-2-3-14-37)34-12-11-27(24)43-28-10-9-23(17-25(28)33)35-31(38)36-44(39,40)20-21-5-7-22(32)8-6-21/h5-12,17-19H,2-4,13-16,20H2,1H3,(H2,35,36,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	418	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of FLT1 (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50399540 (FORETINIB | US10464902, Foretinib | US10882853, Co...) Show SMILES COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCOCC1 Show InChI InChI=1S/C34H34F2N4O6/c1-43-30-20-25-27(21-31(30)45-16-2-13-40-14-17-44-18-15-40)37-12-9-28(25)46-29-8-7-24(19-26(29)36)39-33(42)34(10-11-34)32(41)38-23-5-3-22(35)4-6-23/h3-9,12,19-21H,2,10-11,13-18H2,1H3,(H,38,41)(H,39,42)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	3.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of EGFR (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50399540 (FORETINIB | US10464902, Foretinib | US10882853, Co...) Show SMILES COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCOCC1 Show InChI InChI=1S/C34H34F2N4O6/c1-43-30-20-25-27(21-31(30)45-16-2-13-40-14-17-44-18-15-40)37-12-9-28(25)46-29-8-7-24(19-26(29)36)39-33(42)34(10-11-34)32(41)38-23-5-3-22(35)4-6-23/h3-9,12,19-21H,2,10-11,13-18H2,1H3,(H,38,41)(H,39,42)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	3.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of ALK (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50510569 (CHEMBL4533153) Show SMILES COc1cc2c(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C31H32F2N4O6S/c1-41-29-18-24-26(19-30(29)42-16-4-15-37-13-2-3-14-37)34-12-11-27(24)43-28-10-9-23(17-25(28)33)35-31(38)36-44(39,40)20-21-5-7-22(32)8-6-21/h5-12,17-19H,2-4,13-16,20H2,1H3,(H2,35,36,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of EGFR (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50510569 (CHEMBL4533153) Show SMILES COc1cc2c(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C31H32F2N4O6S/c1-41-29-18-24-26(19-30(29)42-16-4-15-37-13-2-3-14-37)34-12-11-27(24)43-28-10-9-23(17-25(28)33)35-31(38)36-44(39,40)20-21-5-7-22(32)8-6-21/h5-12,17-19H,2-4,13-16,20H2,1H3,(H2,35,36,38)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of ALK (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007 BindingDB Entry DOI: 10.7270/Q23F4SZM
					More data for this Ligand-Target Pair