Compile Data Set for Download or QSAR

Found 36 hits Enz. Inhib. hit(s) with all data for entry = 50007798   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM168281 (US9669031, 109 8-chloro-6-(pyrimidin-4-ylamino)spi...) Show SMILES Clc1cc(Nc2ccncn2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C16H16ClN5O2/c17-10-8-11(20-12-4-7-18-9-19-12)15(24)22-13(10)14(23)21-16(22)5-2-1-3-6-16/h4,7-9H,1-3,5-6H2,(H,21,23)(H,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant GST-tagged MNK1 (unknown origin) using eIF4E-derived peptide as substrate in presence of ATP at km concentration by ADP-Glo...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM168281 (US9669031, 109 8-chloro-6-(pyrimidin-4-ylamino)spi...) Show SMILES Clc1cc(Nc2ccncn2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C16H16ClN5O2/c17-10-8-11(20-12-4-7-18-9-19-12)15(24)22-13(10)14(23)21-16(22)5-2-1-3-6-16/h4,7-9H,1-3,5-6H2,(H,21,23)(H,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant His-tagged MNK2 (unknown origin) using eIF4E-derived peptide as substrate in presence of ATP at Km concentration by ADP-Glo...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50263263 (CHEMBL4073443) Show SMILES Cc1cc(Nc2cc(N)ncn2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C17H20N6O2/c1-10-7-11(21-13-8-12(18)19-9-20-13)16(25)23-14(10)15(24)22-17(23)5-3-2-4-6-17/h7-9H,2-6H2,1H3,(H,22,24)(H3,18,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant His-tagged MNK2 (unknown origin) using eIF4E-derived peptide as substrate in presence of ATP at Km concentration by ADP-Glo...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair				3D Structure (crystal)
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50263263 (CHEMBL4073443) Show SMILES Cc1cc(Nc2cc(N)ncn2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C17H20N6O2/c1-10-7-11(21-13-8-12(18)19-9-20-13)16(25)23-14(10)15(24)22-17(23)5-3-2-4-6-17/h7-9H,2-6H2,1H3,(H,22,24)(H3,18,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant GST-tagged MNK1 (unknown origin) using eIF4E-derived peptide as substrate in presence of ATP at km concentration by ADP-Glo...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50512740 (CHEMBL4449736) Show SMILES Clc1cc(Nc2ccncc2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C17H17ClN4O2/c18-12-10-13(20-11-4-8-19-9-5-11)16(24)22-14(12)15(23)21-17(22)6-2-1-3-7-17/h4-5,8-10H,1-3,6-7H2,(H,19,20)(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant GST-tagged MNK1 (unknown origin) using eIF4E-derived peptide as substrate in presence of ATP at km concentration by ADP-Glo...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50512741 (CHEMBL4466664) Show SMILES Clc1cc(Nc2ccon2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C15H15ClN4O3/c16-9-8-10(17-11-4-7-23-19-11)14(22)20-12(9)13(21)18-15(20)5-2-1-3-6-15/h4,7-8H,1-3,5-6H2,(H,17,19)(H,18,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant His-tagged MNK2 (unknown origin) using eIF4E-derived peptide as substrate in presence of ATP at Km concentration by ADP-Glo...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50512739 (CHEMBL4535537) Show SMILES Fc1cnccc1Nc1cc(Cl)c2C(=O)NC3(CCCCC3)n2c1=O Show InChI InChI=1S/C17H16ClFN4O2/c18-10-8-13(21-12-4-7-20-9-11(12)19)16(25)23-14(10)15(24)22-17(23)5-2-1-3-6-17/h4,7-9H,1-3,5-6H2,(H,20,21)(H,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant GST-tagged MNK1 (unknown origin) using eIF4E-derived peptide as substrate in presence of ATP at km concentration by ADP-Glo...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50512740 (CHEMBL4449736) Show SMILES Clc1cc(Nc2ccncc2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C17H17ClN4O2/c18-12-10-13(20-11-4-8-19-9-5-11)16(24)22-14(12)15(23)21-17(22)6-2-1-3-7-17/h4-5,8-10H,1-3,6-7H2,(H,19,20)(H,21,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	82	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant His-tagged MNK2 (unknown origin) using eIF4E-derived peptide as substrate in presence of ATP at Km concentration by ADP-Glo...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50512742 (CHEMBL4454334) Show SMILES Oc1cc(Nc2cc(Cl)c3C(=O)NC4(CCCCC4)n3c2=O)ccn1 Show InChI InChI=1S/C17H17ClN4O3/c18-11-9-12(20-10-4-7-19-13(23)8-10)16(25)22-14(11)15(24)21-17(22)5-2-1-3-6-17/h4,7-9H,1-3,5-6H2,(H,21,24)(H2,19,20,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	221	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant GST-tagged MNK1 (unknown origin) using eIF4E-derived peptide as substrate in presence of ATP at km concentration by ADP-Glo...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50512741 (CHEMBL4466664) Show SMILES Clc1cc(Nc2ccon2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C15H15ClN4O3/c16-9-8-10(17-11-4-7-23-19-11)14(22)20-12(9)13(21)18-15(20)5-2-1-3-6-15/h4,7-8H,1-3,5-6H2,(H,17,19)(H,18,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	341	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant GST-tagged MNK1 (unknown origin) using eIF4E-derived peptide as substrate in presence of ATP at km concentration by ADP-Glo...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50512739 (CHEMBL4535537) Show SMILES Fc1cnccc1Nc1cc(Cl)c2C(=O)NC3(CCCCC3)n2c1=O Show InChI InChI=1S/C17H16ClFN4O2/c18-10-8-13(21-12-4-7-20-9-11(12)19)16(25)23-14(10)15(24)22-17(23)5-2-1-3-6-17/h4,7-9H,1-3,5-6H2,(H,20,21)(H,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	438	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant His-tagged MNK2 (unknown origin) using eIF4E-derived peptide as substrate in presence of ATP at Km concentration by ADP-Glo...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50512742 (CHEMBL4454334) Show SMILES Oc1cc(Nc2cc(Cl)c3C(=O)NC4(CCCCC4)n3c2=O)ccn1 Show InChI InChI=1S/C17H17ClN4O3/c18-11-9-12(20-10-4-7-19-13(23)8-10)16(25)22-14(11)15(24)21-17(22)5-2-1-3-6-17/h4,7-9H,1-3,5-6H2,(H,21,24)(H2,19,20,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.28E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant His-tagged MNK2 (unknown origin) using eIF4E-derived peptide as substrate in presence of ATP at Km concentration by ADP-Glo...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM168281 (US9669031, 109 8-chloro-6-(pyrimidin-4-ylamino)spi...) Show SMILES Clc1cc(Nc2ccncn2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C16H16ClN5O2/c17-10-8-11(20-12-4-7-18-9-19-12)15(24)22-13(10)14(23)21-16(22)5-2-1-3-6-16/h4,7-9H,1-3,5-6H2,(H,21,23)(H,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Competitive inhibition of recombinant His-tagged MNK2 (unknown origin) using eIF4E derived peptide as substrate at Km concentration in presence of AT...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM168281 (US9669031, 109 8-chloro-6-(pyrimidin-4-ylamino)spi...) Show SMILES Clc1cc(Nc2ccncn2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C16H16ClN5O2/c17-10-8-11(20-12-4-7-18-9-19-12)15(24)22-13(10)14(23)21-16(22)5-2-1-3-6-16/h4,7-9H,1-3,5-6H2,(H,21,23)(H,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Competitive inhibition of recombinant His-tagged MNK2 (unknown origin) using eIF4E derived peptide as substrate at concentration of Km/10 in presence...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM168281 (US9669031, 109 8-chloro-6-(pyrimidin-4-ylamino)spi...) Show SMILES Clc1cc(Nc2ccncn2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C16H16ClN5O2/c17-10-8-11(20-12-4-7-18-9-19-12)15(24)22-13(10)14(23)21-16(22)5-2-1-3-6-16/h4,7-9H,1-3,5-6H2,(H,21,23)(H,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Competitive inhibition of recombinant His-tagged MNK2 (unknown origin) using eIF4E derived peptide as substrate at concentration of 10XKm in presence...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM168281 (US9669031, 109 8-chloro-6-(pyrimidin-4-ylamino)spi...) Show SMILES Clc1cc(Nc2ccncn2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C16H16ClN5O2/c17-10-8-11(20-12-4-7-18-9-19-12)15(24)22-13(10)14(23)21-16(22)5-2-1-3-6-16/h4,7-9H,1-3,5-6H2,(H,21,23)(H,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Competitive inhibition of recombinant GST-tagged MNK1 (unknown origin) using eIF4E derived peptide as substrate at concentration of 10XKm in presence...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM168281 (US9669031, 109 8-chloro-6-(pyrimidin-4-ylamino)spi...) Show SMILES Clc1cc(Nc2ccncn2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C16H16ClN5O2/c17-10-8-11(20-12-4-7-18-9-19-12)15(24)22-13(10)14(23)21-16(22)5-2-1-3-6-16/h4,7-9H,1-3,5-6H2,(H,21,23)(H,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Competitive inhibition of recombinant GST-tagged MNK1 (unknown origin) using eIF4E derived peptide as substrate in presence of ATP at Km concentratio...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM168281 (US9669031, 109 8-chloro-6-(pyrimidin-4-ylamino)spi...) Show SMILES Clc1cc(Nc2ccncn2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C16H16ClN5O2/c17-10-8-11(20-12-4-7-18-9-19-12)15(24)22-13(10)14(23)21-16(22)5-2-1-3-6-16/h4,7-9H,1-3,5-6H2,(H,21,23)(H,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Competitive inhibition of recombinant His-tagged MNK2 (unknown origin) using eIF4E derived peptide as substrate in presence of ATP at concentration o...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM168281 (US9669031, 109 8-chloro-6-(pyrimidin-4-ylamino)spi...) Show SMILES Clc1cc(Nc2ccncn2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C16H16ClN5O2/c17-10-8-11(20-12-4-7-18-9-19-12)15(24)22-13(10)14(23)21-16(22)5-2-1-3-6-16/h4,7-9H,1-3,5-6H2,(H,21,23)(H,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Competitive inhibition of recombinant GST-tagged MNK1 (unknown origin) using eIF4E derived peptide as substrate in presence of ATP at concentration o...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM168281 (US9669031, 109 8-chloro-6-(pyrimidin-4-ylamino)spi...) Show SMILES Clc1cc(Nc2ccncn2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C16H16ClN5O2/c17-10-8-11(20-12-4-7-18-9-19-12)15(24)22-13(10)14(23)21-16(22)5-2-1-3-6-16/h4,7-9H,1-3,5-6H2,(H,21,23)(H,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Competitive inhibition of recombinant GST-tagged MNK1 (unknown origin) using eIF4E derived peptide as substrate at concentration of Km/10 in presence...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM168281 (US9669031, 109 8-chloro-6-(pyrimidin-4-ylamino)spi...) Show SMILES Clc1cc(Nc2ccncn2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C16H16ClN5O2/c17-10-8-11(20-12-4-7-18-9-19-12)15(24)22-13(10)14(23)21-16(22)5-2-1-3-6-16/h4,7-9H,1-3,5-6H2,(H,21,23)(H,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Competitive inhibition of recombinant His-tagged MNK2 (unknown origin) using eIF4E derived peptide as substrate in presence of ATP at Km concentratio...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM168281 (US9669031, 109 8-chloro-6-(pyrimidin-4-ylamino)spi...) Show SMILES Clc1cc(Nc2ccncn2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C16H16ClN5O2/c17-10-8-11(20-12-4-7-18-9-19-12)15(24)22-13(10)14(23)21-16(22)5-2-1-3-6-16/h4,7-9H,1-3,5-6H2,(H,21,23)(H,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Competitive inhibition of recombinant His-tagged MNK2 (unknown origin) using eIF4E derived peptide as substrate in presence of ATP at concentration o...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM168281 (US9669031, 109 8-chloro-6-(pyrimidin-4-ylamino)spi...) Show SMILES Clc1cc(Nc2ccncn2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C16H16ClN5O2/c17-10-8-11(20-12-4-7-18-9-19-12)15(24)22-13(10)14(23)21-16(22)5-2-1-3-6-16/h4,7-9H,1-3,5-6H2,(H,21,23)(H,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Competitive inhibition of recombinant GST-tagged MNK1 (unknown origin) using eIF4E derived peptide as substrate at Km concentration in presence of AT...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM168281 (US9669031, 109 8-chloro-6-(pyrimidin-4-ylamino)spi...) Show SMILES Clc1cc(Nc2ccncn2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C16H16ClN5O2/c17-10-8-11(20-12-4-7-18-9-19-12)15(24)22-13(10)14(23)21-16(22)5-2-1-3-6-16/h4,7-9H,1-3,5-6H2,(H,21,23)(H,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Competitive inhibition of recombinant GST-tagged MNK1 (unknown origin) using eIF4E derived peptide as substrate in presence of ATP at concentration o...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50512740 (CHEMBL4449736) Show SMILES Clc1cc(Nc2ccncc2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C17H17ClN4O2/c18-12-10-13(20-11-4-8-19-9-5-11)16(24)22-14(12)15(23)21-17(22)6-2-1-3-7-17/h4-5,8-10H,1-3,6-7H2,(H,19,20)(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Competitive inhibition of recombinant GST-tagged MNK1 (unknown origin) using eIF4E derived peptide as substrate in presence of ATP at Km concentratio...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50512740 (CHEMBL4449736) Show SMILES Clc1cc(Nc2ccncc2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C17H17ClN4O2/c18-12-10-13(20-11-4-8-19-9-5-11)16(24)22-14(12)15(23)21-17(22)6-2-1-3-7-17/h4-5,8-10H,1-3,6-7H2,(H,19,20)(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Competitive inhibition of recombinant GST-tagged MNK1 (unknown origin) using eIF4E derived peptide as substrate in presence of ATP at concentration o...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50512740 (CHEMBL4449736) Show SMILES Clc1cc(Nc2ccncc2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C17H17ClN4O2/c18-12-10-13(20-11-4-8-19-9-5-11)16(24)22-14(12)15(23)21-17(22)6-2-1-3-7-17/h4-5,8-10H,1-3,6-7H2,(H,19,20)(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Competitive inhibition of recombinant GST-tagged MNK1 (unknown origin) using eIF4E derived peptide as substrate at Km concentration in presence of AT...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50512740 (CHEMBL4449736) Show SMILES Clc1cc(Nc2ccncc2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C17H17ClN4O2/c18-12-10-13(20-11-4-8-19-9-5-11)16(24)22-14(12)15(23)21-17(22)6-2-1-3-7-17/h4-5,8-10H,1-3,6-7H2,(H,19,20)(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Competitive inhibition of recombinant GST-tagged MNK1 (unknown origin) using eIF4E derived peptide as substrate in presence of ATP at concentration o...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50512740 (CHEMBL4449736) Show SMILES Clc1cc(Nc2ccncc2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C17H17ClN4O2/c18-12-10-13(20-11-4-8-19-9-5-11)16(24)22-14(12)15(23)21-17(22)6-2-1-3-7-17/h4-5,8-10H,1-3,6-7H2,(H,19,20)(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Competitive inhibition of recombinant GST-tagged MNK1 (unknown origin) using eIF4E derived peptide as substrate at concentration of Km/10 in presence...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50512740 (CHEMBL4449736) Show SMILES Clc1cc(Nc2ccncc2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C17H17ClN4O2/c18-12-10-13(20-11-4-8-19-9-5-11)16(24)22-14(12)15(23)21-17(22)6-2-1-3-7-17/h4-5,8-10H,1-3,6-7H2,(H,19,20)(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Competitive inhibition of recombinant GST-tagged MNK1 (unknown origin) using eIF4E derived peptide as substrate at concentration of 10XKm in presence...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50512740 (CHEMBL4449736) Show SMILES Clc1cc(Nc2ccncc2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C17H17ClN4O2/c18-12-10-13(20-11-4-8-19-9-5-11)16(24)22-14(12)15(23)21-17(22)6-2-1-3-7-17/h4-5,8-10H,1-3,6-7H2,(H,19,20)(H,21,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	159	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Competitive inhibition of recombinant His-tagged MNK2 (unknown origin) using eIF4E derived peptide as substrate in presence of ATP at Km concentratio...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50512740 (CHEMBL4449736) Show SMILES Clc1cc(Nc2ccncc2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C17H17ClN4O2/c18-12-10-13(20-11-4-8-19-9-5-11)16(24)22-14(12)15(23)21-17(22)6-2-1-3-7-17/h4-5,8-10H,1-3,6-7H2,(H,19,20)(H,21,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	163	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Competitive inhibition of recombinant His-tagged MNK2 (unknown origin) using eIF4E derived peptide as substrate at concentration of 10XKm in presence...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50512740 (CHEMBL4449736) Show SMILES Clc1cc(Nc2ccncc2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C17H17ClN4O2/c18-12-10-13(20-11-4-8-19-9-5-11)16(24)22-14(12)15(23)21-17(22)6-2-1-3-7-17/h4-5,8-10H,1-3,6-7H2,(H,19,20)(H,21,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	169	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Competitive inhibition of recombinant His-tagged MNK2 (unknown origin) using eIF4E derived peptide as substrate in presence of ATP at concentration o...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50512740 (CHEMBL4449736) Show SMILES Clc1cc(Nc2ccncc2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C17H17ClN4O2/c18-12-10-13(20-11-4-8-19-9-5-11)16(24)22-14(12)15(23)21-17(22)6-2-1-3-7-17/h4-5,8-10H,1-3,6-7H2,(H,19,20)(H,21,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	182	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Competitive inhibition of recombinant His-tagged MNK2 (unknown origin) using eIF4E derived peptide as substrate at Km concentration in presence of AT...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50512740 (CHEMBL4449736) Show SMILES Clc1cc(Nc2ccncc2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C17H17ClN4O2/c18-12-10-13(20-11-4-8-19-9-5-11)16(24)22-14(12)15(23)21-17(22)6-2-1-3-7-17/h4-5,8-10H,1-3,6-7H2,(H,19,20)(H,21,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Competitive inhibition of recombinant His-tagged MNK2 (unknown origin) using eIF4E derived peptide as substrate at concentration of Km/10 in presence...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50512740 (CHEMBL4449736) Show SMILES Clc1cc(Nc2ccncc2)c(=O)n2c1C(=O)NC21CCCCC1 Show InChI InChI=1S/C17H17ClN4O2/c18-12-10-13(20-11-4-8-19-9-5-11)16(24)22-14(12)15(23)21-17(22)6-2-1-3-7-17/h4-5,8-10H,1-3,6-7H2,(H,19,20)(H,21,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	209	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Competitive inhibition of recombinant His-tagged MNK2 (unknown origin) using eIF4E derived peptide as substrate in presence of ATP at concentration o...				Bioorg Med Chem Lett 29: 2650-2654 (2019) Article DOI: 10.1016/j.bmcl.2019.07.043 BindingDB Entry DOI: 10.7270/Q2B56P2W
					More data for this Ligand-Target Pair