Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1B (Homo sapiens (Human)) | BDBM50069315![]() (C-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-[4-(...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | PubMed | 0.640 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherche Pierre FABRE Curated by ChEMBL | Assay Description In vitro binding affinity was determined towards cloned human 5-hydroxytryptamine 1B receptor using [3H]-5-CT radioligand | Bioorg Med Chem Lett 8: 675-80 (1999) BindingDB Entry DOI: 10.7270/Q24B30F8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50033383![]() ((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | DrugBank PubMed | 0.760 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherche Pierre FABRE Curated by ChEMBL | Assay Description In vitro binding affinity was determined towards cloned human 5-hydroxytryptamine 1D receptor using [3H]-5-CT radioligand | Bioorg Med Chem Lett 8: 675-80 (1999) BindingDB Entry DOI: 10.7270/Q24B30F8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50069315![]() (C-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-[4-(...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | PubMed | 0.890 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherche Pierre FABRE Curated by ChEMBL | Assay Description In vitro binding affinity was determined towards cloned human 5-hydroxytryptamine 1D receptor using [3H]-5-CT radioligand | Bioorg Med Chem Lett 8: 675-80 (1999) BindingDB Entry DOI: 10.7270/Q24B30F8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1B (Homo sapiens (Human)) | BDBM50033383![]() ((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | DrugBank PubMed | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherche Pierre FABRE Curated by ChEMBL | Assay Description In vitro binding affinity was determined towards cloned human 5-hydroxytryptamine 1B receptor using [3H]-5-CT radioligand | Bioorg Med Chem Lett 8: 675-80 (1999) BindingDB Entry DOI: 10.7270/Q24B30F8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50005835![]() ((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents | DrugBank PubMed | 8.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherche Pierre FABRE Curated by ChEMBL | Assay Description In vitro binding affinity was determined towards cloned human 5-hydroxytryptamine 1D receptor using [3H]-5-CT radioligand | Bioorg Med Chem Lett 8: 675-80 (1999) BindingDB Entry DOI: 10.7270/Q24B30F8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50069315![]() (C-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-[4-(...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | PubMed | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherche Pierre FABRE Curated by ChEMBL | Assay Description In vitro binding affinity was determined towards cloned human 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand | Bioorg Med Chem Lett 8: 675-80 (1999) BindingDB Entry DOI: 10.7270/Q24B30F8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1B (Homo sapiens (Human)) | BDBM50005835![]() ((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents | DrugBank PubMed | 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherche Pierre FABRE Curated by ChEMBL | Assay Description In vitro binding affinity was determined towards cloned human 5-hydroxytryptamine 1B receptor using [3H]-5-CT radioligand | Bioorg Med Chem Lett 8: 675-80 (1999) BindingDB Entry DOI: 10.7270/Q24B30F8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50033383![]() ((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | PubMed | 124 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherche Pierre FABRE Curated by ChEMBL | Assay Description In vitro binding affinity was determined towards cloned human 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand | Bioorg Med Chem Lett 8: 675-80 (1999) BindingDB Entry DOI: 10.7270/Q24B30F8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50005835![]() ((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents | PubMed | 407 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherche Pierre FABRE Curated by ChEMBL | Assay Description In vitro binding affinity was determined towards cloned human 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand | Bioorg Med Chem Lett 8: 675-80 (1999) BindingDB Entry DOI: 10.7270/Q24B30F8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1B (Homo sapiens (Human)) | BDBM50033383![]() ((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | DrugBank PubMed | n/a | n/a | n/a | n/a | 16 | n/a | n/a | n/a | n/a |
Centre de Recherche Pierre FABRE Curated by ChEMBL | Assay Description Effective concentration of the compound determined by measuring inhibition of forskolin-stimulated c-AMP formation at 5-hydroxytryptamine 1B receptor... | Bioorg Med Chem Lett 8: 675-80 (1999) BindingDB Entry DOI: 10.7270/Q24B30F8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1B (Homo sapiens (Human)) | BDBM50005835![]() ((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents | DrugBank PubMed | n/a | n/a | n/a | n/a | 38 | n/a | n/a | n/a | n/a |
Centre de Recherche Pierre FABRE Curated by ChEMBL | Assay Description Effective concentration of the compound determined by measuring inhibition of forskolin-stimulated c-AMP formation at 5-hydroxytryptamine 1B receptor... | Bioorg Med Chem Lett 8: 675-80 (1999) BindingDB Entry DOI: 10.7270/Q24B30F8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1B (Homo sapiens (Human)) | BDBM50069315![]() (C-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-[4-(...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | n/a | n/a | 0.580 | n/a | n/a | n/a | n/a |
Centre de Recherche Pierre FABRE Curated by ChEMBL | Assay Description Effective concentration of the compound determined by measuring inhibition of forskolin-stimulated c-AMP formation at 5-hydroxytryptamine 1B receptor... | Bioorg Med Chem Lett 8: 675-80 (1999) BindingDB Entry DOI: 10.7270/Q24B30F8 | |||||||||||
More data for this Ligand-Target Pair |