Compile Data Set for Download or QSAR

Found 55 hits Enz. Inhib. hit(s) with all data for entry = 50008283   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50517420 (CHEMBL4513589) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC1(C)CC1)n(CC1(N)CC1)c2=O |r| Show InChI InChI=1S/C23H26N6O2/c1-12-17-15(19(30)25-12)10-16(26-17)13-4-3-5-14-18(13)27-21(28-22(2)6-7-22)29(20(14)31)11-23(24)8-9-23/h3-5,10,12,26H,6-9,11,24H2,1-2H3,(H,25,30)(H,27,28)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.0200	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50517431 (CHEMBL4471849) Show SMILES CC(c1cn(C)cn1)n1c(NC2(C)CC2)nc2c(cccc2c1=O)-c1cc2C(=O)N[C@H](C)c2[nH]1 |r| Show InChI InChI=1S/C25H27N7O2/c1-13-20-17(22(33)27-13)10-18(28-20)15-6-5-7-16-21(15)29-24(30-25(3)8-9-25)32(23(16)34)14(2)19-11-31(4)12-26-19/h5-7,10-14,28H,8-9H2,1-4H3,(H,27,33)(H,29,30)/t13-,14?/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.0300	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50517433 (CHEMBL4450494) Show SMILES C[C@@H](c1cn(C)cn1)n1c(NC2(C)CC2)nc2c(cccc2c1=O)-c1cc2C(=O)N[C@H](C)c2[nH]1 |r| Show InChI InChI=1S/C25H27N7O2/c1-13-20-17(22(33)27-13)10-18(28-20)15-6-5-7-16-21(15)29-24(30-25(3)8-9-25)32(23(16)34)14(2)19-11-31(4)12-26-19/h5-7,10-14,28H,8-9H2,1-4H3,(H,27,33)(H,29,30)/t13-,14+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.0300	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50517428 (CHEMBL4568404) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC1(C)CC1)n(c2=O)C1(C)CC1 |r| Show InChI InChI=1S/C23H25N5O2/c1-12-17-15(19(29)24-12)11-16(25-17)13-5-4-6-14-18(13)26-21(27-22(2)7-8-22)28(20(14)30)23(3)9-10-23/h4-6,11-12,25H,7-10H2,1-3H3,(H,24,29)(H,26,27)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	0.0500	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50517428 (CHEMBL4568404) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC1(C)CC1)n(c2=O)C1(C)CC1 |r| Show InChI InChI=1S/C23H25N5O2/c1-12-17-15(19(29)24-12)11-16(25-17)13-5-4-6-14-18(13)26-21(27-22(2)7-8-22)28(20(14)30)23(3)9-10-23/h4-6,11-12,25H,7-10H2,1-3H3,(H,24,29)(H,26,27)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	0.0500	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50517429 (CHEMBL4436404) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC1(C)CC1)n(CC1CC1)c2=O |r| Show InChI InChI=1S/C23H25N5O2/c1-12-18-16(20(29)24-12)10-17(25-18)14-4-3-5-15-19(14)26-22(27-23(2)8-9-23)28(21(15)30)11-13-6-7-13/h3-5,10,12-13,25H,6-9,11H2,1-2H3,(H,24,29)(H,26,27)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.0600	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM238725 (US9394297, 406) Show SMILES CC(C)n1c(NC(C)(C)C)nc2c(cccc2c1=O)-c1cc2C(=O)N[C@H](C)c2[nH]1 Show InChI InChI=1S/C22H27N5O2/c1-11(2)27-20(29)14-9-7-8-13(18(14)25-21(27)26-22(4,5)6)16-10-15-17(24-16)12(3)23-19(15)28/h7-12,24H,1-6H3,(H,23,28)(H,25,26)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.0700	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50517430 (CHEMBL4446411) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC1(C)CC1)n(CC1(O)CC1)c2=O |r| Show InChI InChI=1S/C23H25N5O3/c1-12-17-15(19(29)24-12)10-16(25-17)13-4-3-5-14-18(13)26-21(27-22(2)6-7-22)28(20(14)30)11-23(31)8-9-23/h3-5,10,12,25,31H,6-9,11H2,1-2H3,(H,24,29)(H,26,27)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50517435 (CHEMBL4441708) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(CC1CC1)c2=O |r| Show InChI InChI=1S/C23H27N5O2/c1-12-18-16(20(29)24-12)10-17(25-18)14-6-5-7-15-19(14)26-22(27-23(2,3)4)28(21(15)30)11-13-8-9-13/h5-7,10,12-13,25H,8-9,11H2,1-4H3,(H,24,29)(H,26,27)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238805 (US9394297, 492) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC1(C)CC1)n(C1CC1)c2=O Show InChI InChI=1S/C22H23N5O2/c1-11-17-15(19(28)23-11)10-16(24-17)13-4-3-5-14-18(13)25-21(26-22(2)8-9-22)27(20(14)29)12-6-7-12/h3-5,10-12,24H,6-9H2,1-2H3,(H,23,28)(H,25,26)/t11-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.0900	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50517435 (CHEMBL4441708) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(CC1CC1)c2=O |r| Show InChI InChI=1S/C23H27N5O2/c1-12-18-16(20(29)24-12)10-17(25-18)14-6-5-7-15-19(14)26-22(27-23(2,3)4)28(21(15)30)11-13-8-9-13/h5-7,10,12-13,25H,8-9,11H2,1-4H3,(H,24,29)(H,26,27)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.0900	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM238805 (US9394297, 492) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC1(C)CC1)n(C1CC1)c2=O Show InChI InChI=1S/C22H23N5O2/c1-11-17-15(19(28)23-11)10-16(24-17)13-4-3-5-14-18(13)25-21(26-22(2)8-9-22)27(20(14)29)12-6-7-12/h3-5,10-12,24H,6-9H2,1-2H3,(H,23,28)(H,25,26)/t11-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50517431 (CHEMBL4471849) Show SMILES CC(c1cn(C)cn1)n1c(NC2(C)CC2)nc2c(cccc2c1=O)-c1cc2C(=O)N[C@H](C)c2[nH]1 |r| Show InChI InChI=1S/C25H27N7O2/c1-13-20-17(22(33)27-13)10-18(28-20)15-6-5-7-16-21(15)29-24(30-25(3)8-9-25)32(23(16)34)14(2)19-11-31(4)12-26-19/h5-7,10-14,28H,8-9H2,1-4H3,(H,27,33)(H,29,30)/t13-,14?/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50517415 (CHEMBL4468122) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(CC1(N)CC1)c2=O |r| Show InChI InChI=1S/C23H28N6O2/c1-12-17-15(19(30)25-12)10-16(26-17)13-6-5-7-14-18(13)27-21(28-22(2,3)4)29(20(14)31)11-23(24)8-9-23/h5-7,10,12,26H,8-9,11,24H2,1-4H3,(H,25,30)(H,27,28)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238788 (US9394297, 475) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(C1CC1)c2=O Show InChI InChI=1S/C22H25N5O2/c1-11-17-15(19(28)23-11)10-16(24-17)13-6-5-7-14-18(13)25-21(26-22(2,3)4)27(20(14)29)12-8-9-12/h5-7,10-12,24H,8-9H2,1-4H3,(H,23,28)(H,25,26)/t11-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50517429 (CHEMBL4436404) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC1(C)CC1)n(CC1CC1)c2=O |r| Show InChI InChI=1S/C23H25N5O2/c1-12-18-16(20(29)24-12)10-17(25-18)14-4-3-5-15-19(14)26-22(27-23(2)8-9-23)28(21(15)30)11-13-6-7-13/h3-5,10,12-13,25H,6-9,11H2,1-2H3,(H,24,29)(H,26,27)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50517418 (CHEMBL4464030) Show SMILES CC(c1cn(C)cn1)n1c(NC(C)(C)C)nc2c(cccc2c1=O)-c1cc2C(=O)N[C@H](C)c2[nH]1 |r| Show InChI InChI=1S/C25H29N7O2/c1-13-20-17(22(33)27-13)10-18(28-20)15-8-7-9-16-21(15)29-24(30-25(3,4)5)32(23(16)34)14(2)19-11-31(6)12-26-19/h7-14,28H,1-6H3,(H,27,33)(H,29,30)/t13-,14?/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238725 (US9394297, 406) Show SMILES CC(C)n1c(NC(C)(C)C)nc2c(cccc2c1=O)-c1cc2C(=O)N[C@H](C)c2[nH]1 Show InChI InChI=1S/C22H27N5O2/c1-11(2)27-20(29)14-9-7-8-13(18(14)25-21(27)26-22(4,5)6)16-10-15-17(24-16)12(3)23-19(15)28/h7-12,24H,1-6H3,(H,23,28)(H,25,26)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50517423 (CHEMBL4591512) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(CC1(O)CC1)c2=O |r| Show InChI InChI=1S/C23H27N5O3/c1-12-17-15(19(29)24-12)10-16(25-17)13-6-5-7-14-18(13)26-21(27-22(2,3)4)28(20(14)30)11-23(31)8-9-23/h5-7,10,12,25,31H,8-9,11H2,1-4H3,(H,24,29)(H,26,27)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50517421 (CHEMBL4461181) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(C[C@H]1CCCO1)c2=O |r| Show InChI InChI=1S/C24H29N5O3/c1-13-19-17(21(30)25-13)11-18(26-19)15-8-5-9-16-20(15)27-23(28-24(2,3)4)29(22(16)31)12-14-7-6-10-32-14/h5,8-9,11,13-14,26H,6-7,10,12H2,1-4H3,(H,25,30)(H,27,28)/t13-,14-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50517434 (CHEMBL4470271) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC1(C)CC1)n(C1CCC1)c2=O |r| Show InChI InChI=1S/C23H25N5O2/c1-12-18-16(20(29)24-12)11-17(25-18)14-7-4-8-15-19(14)26-22(27-23(2)9-10-23)28(21(15)30)13-5-3-6-13/h4,7-8,11-13,25H,3,5-6,9-10H2,1-2H3,(H,24,29)(H,26,27)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50517433 (CHEMBL4450494) Show SMILES C[C@@H](c1cn(C)cn1)n1c(NC2(C)CC2)nc2c(cccc2c1=O)-c1cc2C(=O)N[C@H](C)c2[nH]1 |r| Show InChI InChI=1S/C25H27N7O2/c1-13-20-17(22(33)27-13)10-18(28-20)15-6-5-7-16-21(15)29-24(30-25(3)8-9-25)32(23(16)34)14(2)19-11-31(4)12-26-19/h5-7,10-14,28H,8-9H2,1-4H3,(H,27,33)(H,29,30)/t13-,14+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50517420 (CHEMBL4513589) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC1(C)CC1)n(CC1(N)CC1)c2=O |r| Show InChI InChI=1S/C23H26N6O2/c1-12-17-15(19(30)25-12)10-16(26-17)13-4-3-5-14-18(13)27-21(28-22(2)6-7-22)29(20(14)31)11-23(24)8-9-23/h3-5,10,12,26H,6-9,11,24H2,1-2H3,(H,25,30)(H,27,28)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50517424 (CHEMBL4456165) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(c2=O)C1(C)CC1 |r| Show InChI InChI=1S/C23H27N5O2/c1-12-17-15(19(29)24-12)11-16(25-17)13-7-6-8-14-18(13)26-21(27-22(2,3)4)28(20(14)30)23(5)9-10-23/h6-8,11-12,25H,9-10H2,1-5H3,(H,24,29)(H,26,27)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50517422 (CHEMBL4472803) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(CC1COC1)c2=O |r| Show InChI InChI=1S/C23H27N5O3/c1-12-18-16(20(29)24-12)8-17(25-18)14-6-5-7-15-19(14)26-22(27-23(2,3)4)28(21(15)30)9-13-10-31-11-13/h5-8,12-13,25H,9-11H2,1-4H3,(H,24,29)(H,26,27)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50517414 (CHEMBL4563904) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(Cc1cn(C)cn1)c2=O |r| Show InChI InChI=1S/C24H27N7O2/c1-13-19-17(21(32)26-13)9-18(27-19)15-7-6-8-16-20(15)28-23(29-24(2,3)4)31(22(16)33)11-14-10-30(5)12-25-14/h6-10,12-13,27H,11H2,1-5H3,(H,26,32)(H,28,29)/t13-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM238788 (US9394297, 475) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(C1CC1)c2=O Show InChI InChI=1S/C22H25N5O2/c1-11-17-15(19(28)23-11)10-16(24-17)13-6-5-7-14-18(13)25-21(26-22(2,3)4)27(20(14)29)12-8-9-12/h5-7,10-12,24H,8-9H2,1-4H3,(H,23,28)(H,25,26)/t11-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50517434 (CHEMBL4470271) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC1(C)CC1)n(C1CCC1)c2=O |r| Show InChI InChI=1S/C23H25N5O2/c1-12-18-16(20(29)24-12)11-17(25-18)14-7-4-8-15-19(14)26-22(27-23(2)9-10-23)28(21(15)30)13-5-3-6-13/h4,7-8,11-13,25H,3,5-6,9-10H2,1-2H3,(H,24,29)(H,26,27)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.180	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50517430 (CHEMBL4446411) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC1(C)CC1)n(CC1(O)CC1)c2=O |r| Show InChI InChI=1S/C23H25N5O3/c1-12-17-15(19(29)24-12)10-16(25-17)13-4-3-5-14-18(13)26-21(27-22(2)6-7-22)28(20(14)30)11-23(31)8-9-23/h3-5,10,12,25,31H,6-9,11H2,1-2H3,(H,24,29)(H,26,27)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.180	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM238767 (US9394297, 451) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC1(C)CC1)n(C)c2=O Show InChI InChI=1S/C20H21N5O2/c1-10-15-13(17(26)21-10)9-14(22-15)11-5-4-6-12-16(11)23-19(25(3)18(12)27)24-20(2)7-8-20/h4-6,9-10,22H,7-8H2,1-3H3,(H,21,26)(H,23,24)/t10-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50517425 (CHEMBL4436502) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(c2=O)C(C)(C)C |r| Show InChI InChI=1S/C23H29N5O2/c1-12-17-15(19(29)24-12)11-16(25-17)13-9-8-10-14-18(13)26-21(27-22(2,3)4)28(20(14)30)23(5,6)7/h8-12,25H,1-7H3,(H,24,29)(H,26,27)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50517423 (CHEMBL4591512) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(CC1(O)CC1)c2=O |r| Show InChI InChI=1S/C23H27N5O3/c1-12-17-15(19(29)24-12)10-16(25-17)13-6-5-7-14-18(13)26-21(27-22(2,3)4)28(20(14)30)11-23(31)8-9-23/h5-7,10,12,25,31H,8-9,11H2,1-4H3,(H,24,29)(H,26,27)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50517415 (CHEMBL4468122) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(CC1(N)CC1)c2=O |r| Show InChI InChI=1S/C23H28N6O2/c1-12-17-15(19(30)25-12)10-16(26-17)13-6-5-7-14-18(13)27-21(28-22(2,3)4)29(20(14)31)11-23(24)8-9-23/h5-7,10,12,26H,8-9,11,24H2,1-4H3,(H,25,30)(H,27,28)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.240	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50517424 (CHEMBL4456165) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(c2=O)C1(C)CC1 |r| Show InChI InChI=1S/C23H27N5O2/c1-12-17-15(19(29)24-12)11-16(25-17)13-7-6-8-14-18(13)26-21(27-22(2,3)4)28(20(14)30)23(5)9-10-23/h6-8,11-12,25H,9-10H2,1-5H3,(H,24,29)(H,26,27)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.290	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM238766 (US9394297, 450) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(C)c2=O Show InChI InChI=1S/C20H23N5O2/c1-10-15-13(17(26)21-10)9-14(22-15)11-7-6-8-12-16(11)23-19(24-20(2,3)4)25(5)18(12)27/h6-10,22H,1-5H3,(H,21,26)(H,23,24)/t10-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	0.340	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50517414 (CHEMBL4563904) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(Cc1cn(C)cn1)c2=O |r| Show InChI InChI=1S/C24H27N7O2/c1-13-19-17(21(32)26-13)9-18(27-19)15-7-6-8-16-20(15)28-23(29-24(2,3)4)31(22(16)33)11-14-10-30(5)12-25-14/h6-10,12-13,27H,11H2,1-5H3,(H,26,32)(H,28,29)/t13-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.350	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50517421 (CHEMBL4461181) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(C[C@H]1CCCO1)c2=O |r| Show InChI InChI=1S/C24H29N5O3/c1-13-19-17(21(30)25-13)11-18(26-19)15-8-5-9-16-20(15)27-23(28-24(2,3)4)29(22(16)31)12-14-7-6-10-32-14/h5,8-9,11,13-14,26H,6-7,10,12H2,1-4H3,(H,25,30)(H,27,28)/t13-,14-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.360	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238767 (US9394297, 451) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC1(C)CC1)n(C)c2=O Show InChI InChI=1S/C20H21N5O2/c1-10-15-13(17(26)21-10)9-14(22-15)11-5-4-6-12-16(11)23-19(25(3)18(12)27)24-20(2)7-8-20/h4-6,9-10,22H,7-8H2,1-3H3,(H,21,26)(H,23,24)/t10-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.380	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238766 (US9394297, 450) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(C)c2=O Show InChI InChI=1S/C20H23N5O2/c1-10-15-13(17(26)21-10)9-14(22-15)11-7-6-8-12-16(11)23-19(24-20(2,3)4)25(5)18(12)27/h6-10,22H,1-5H3,(H,21,26)(H,23,24)/t10-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	0.380	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50517427 (CHEMBL4476513) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(C[C@@H]1CN(C)CCO1)c2=O |r| Show InChI InChI=1S/C25H32N6O3/c1-14-20-18(22(32)26-14)11-19(27-20)16-7-6-8-17-21(16)28-24(29-25(2,3)4)31(23(17)33)13-15-12-30(5)9-10-34-15/h6-8,11,14-15,27H,9-10,12-13H2,1-5H3,(H,26,32)(H,28,29)/t14-,15+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.410	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50517427 (CHEMBL4476513) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(C[C@@H]1CN(C)CCO1)c2=O |r| Show InChI InChI=1S/C25H32N6O3/c1-14-20-18(22(32)26-14)11-19(27-20)16-7-6-8-17-21(16)28-24(29-25(2,3)4)31(23(17)33)13-15-12-30(5)9-10-34-15/h6-8,11,14-15,27H,9-10,12-13H2,1-5H3,(H,26,32)(H,28,29)/t14-,15+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.550	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50517417 (CHEMBL4445845) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(CC(C)(C)N)c2=O |r| Show InChI InChI=1S/C23H30N6O2/c1-12-17-15(19(30)25-12)10-16(26-17)13-8-7-9-14-18(13)27-21(28-22(2,3)4)29(20(14)31)11-23(5,6)24/h7-10,12,26H,11,24H2,1-6H3,(H,25,30)(H,27,28)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.560	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50517422 (CHEMBL4472803) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(CC1COC1)c2=O |r| Show InChI InChI=1S/C23H27N5O3/c1-12-18-16(20(29)24-12)8-17(25-18)14-6-5-7-15-19(14)26-22(27-23(2,3)4)28(21(15)30)9-13-10-31-11-13/h5-8,12-13,25H,9-11H2,1-4H3,(H,24,29)(H,26,27)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50517432 (CHEMBL4463004) Show SMILES C[C@H](c1cn(C)cn1)n1c(NC2(C)CC2)nc2c(cccc2c1=O)-c1cc2C(=O)N[C@H](C)c2[nH]1 |r| Show InChI InChI=1S/C25H27N7O2/c1-13-20-17(22(33)27-13)10-18(28-20)15-6-5-7-16-21(15)29-24(30-25(3)8-9-25)32(23(16)34)14(2)19-11-31(4)12-26-19/h5-7,10-14,28H,8-9H2,1-4H3,(H,27,33)(H,29,30)/t13-,14-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.650	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50517418 (CHEMBL4464030) Show SMILES CC(c1cn(C)cn1)n1c(NC(C)(C)C)nc2c(cccc2c1=O)-c1cc2C(=O)N[C@H](C)c2[nH]1 |r| Show InChI InChI=1S/C25H29N7O2/c1-13-20-17(22(33)27-13)10-18(28-20)15-8-7-9-16-21(15)29-24(30-25(3,4)5)32(23(16)34)14(2)19-11-31(6)12-26-19/h7-14,28H,1-6H3,(H,27,33)(H,29,30)/t13-,14?/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50517425 (CHEMBL4436502) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(c2=O)C(C)(C)C |r| Show InChI InChI=1S/C23H29N5O2/c1-12-17-15(19(29)24-12)11-16(25-17)13-9-8-10-14-18(13)26-21(27-22(2,3)4)28(20(14)30)23(5,6)7/h8-12,25H,1-7H3,(H,24,29)(H,26,27)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.830	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50517416 (CHEMBL4556760) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(C[C@@H]1CCCO1)c2=O |r| Show InChI InChI=1S/C24H29N5O3/c1-13-19-17(21(30)25-13)11-18(26-19)15-8-5-9-16-20(15)27-23(28-24(2,3)4)29(22(16)31)12-14-7-6-10-32-14/h5,8-9,11,13-14,26H,6-7,10,12H2,1-4H3,(H,25,30)(H,27,28)/t13-,14+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50517426 (CHEMBL4443684) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(C[C@H]1CN(C)CCO1)c2=O |r| Show InChI InChI=1S/C25H32N6O3/c1-14-20-18(22(32)26-14)11-19(27-20)16-7-6-8-17-21(16)28-24(29-25(2,3)4)31(23(17)33)13-15-12-30(5)9-10-34-15/h6-8,11,14-15,27H,9-10,12-13H2,1-5H3,(H,26,32)(H,28,29)/t14-,15-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50517426 (CHEMBL4443684) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(C[C@H]1CN(C)CCO1)c2=O |r| Show InChI InChI=1S/C25H32N6O3/c1-14-20-18(22(32)26-14)11-19(27-20)16-7-6-8-17-21(16)28-24(29-25(2,3)4)31(23(17)33)13-15-12-30(5)9-10-34-15/h6-8,11,14-15,27H,9-10,12-13H2,1-5H3,(H,26,32)(H,28,29)/t14-,15-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50517416 (CHEMBL4556760) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(C[C@@H]1CCCO1)c2=O |r| Show InChI InChI=1S/C24H29N5O3/c1-13-19-17(21(30)25-13)11-18(26-19)15-8-5-9-16-20(15)27-23(28-24(2,3)4)29(22(16)31)12-14-7-6-10-32-14/h5,8-9,11,13-14,26H,6-7,10,12H2,1-4H3,(H,25,30)(H,27,28)/t13-,14+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair

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