Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-2' and Ligand = 'BDBM238725'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238725 (US9394297, 406) Show SMILES CC(C)n1c(NC(C)(C)C)nc2c(cccc2c1=O)-c1cc2C(=O)N[C@H](C)c2[nH]1 Show InChI InChI=1S/C22H27N5O2/c1-11(2)27-20(29)14-9-7-8-13(18(14)25-21(27)26-22(4,5)6)16-10-15-17(24-16)12(3)23-19(15)28/h7-12,24H,1-6H3,(H,23,28)(H,25,26)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0120	n/a	n/a	n/a	n/a	7.0	22
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9394297 (2016) BindingDB Entry DOI: 10.7270/Q2G44P78
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238725 (US9394297, 406) Show SMILES CC(C)n1c(NC(C)(C)C)nc2c(cccc2c1=O)-c1cc2C(=O)N[C@H](C)c2[nH]1 Show InChI InChI=1S/C22H27N5O2/c1-11(2)27-20(29)14-9-7-8-13(18(14)25-21(27)26-22(4,5)6)16-10-15-17(24-16)12(3)23-19(15)28/h7-12,24H,1-6H3,(H,23,28)(H,25,26)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733 BindingDB Entry DOI: 10.7270/Q25X2D97
					More data for this Ligand-Target Pair