Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079090![]() (CHEMBL90435 | [(4-{2-[4-((R)-3,10-Dibromo-8-chloro...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Hras Farnesyltransferase (FPT). | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079085![]() (5-(4-{2-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Hras Farnesyltransferase (FPT). | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079075![]() (4-{2-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of [3H]-FPP incorporation into His6-H-Ras-CVLS by farnesyl transferase | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079079![]() (1-(4-{2-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Hras Farnesyltransferase (FPT). | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079074![]() (4-{2-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Hras Farnesyltransferase (FPT). | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM14459![]() ((+)-4-[2-[4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Hras Farnesyltransferase (FPT). | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079084![]() (CHEMBL432573 | [(4-{2-[4-((R)-3,10-Dibromo-8-chlor...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Hras Farnesyltransferase (FPT). | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079089![]() (1-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-be...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Hras Farnesyltransferase (FPT). | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079073![]() (2-(4-{2-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Hras Farnesyltransferase (FPT). | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079083![]() (1-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-be...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of Hras Farnesyl protein transferase(FPT) | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079091![]() (2-(4-{2-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of [3H]-FPP incorporation into His6-H-Ras-CVLS by farnesyl transferase | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079076![]() (5-(4-{2-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Hras Farnesyltransferase (FPT). | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079070![]() (1-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-be...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of Hras Farnesyl protein transferase(FPT) | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079086![]() (3-(4-{2-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of Hras Farnesyl protein transferase(FPT) | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079077![]() (2-(4-{2-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Hras Farnesyltransferase (FPT). | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079072![]() (4-{2-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Hras Farnesyltransferase (FPT). | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079081![]() (2-(4-{2-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of [3H]-FPP incorporation into His6-H-Ras-CVLS by farnesyl transferase | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079088![]() (1-(4-{2-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Hras Farnesyltransferase (FPT). | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079092![]() ((S)-2-Amino-1-(4-{2-[4-((R)-3,10-dibromo-8-chloro-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Hras Farnesyltransferase (FPT). | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079087![]() (2-[1-(2-Amino-acetyl)-piperidin-4-yl]-1-[4-((R)-3,...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Hras Farnesyltransferase (FPT). | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079080![]() (1-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-be...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of [3H]-FPP incorporation into His6-H-Ras-CVLS by farnesyl transferase | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079091![]() (2-(4-{2-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Effect on Ras processing in Cos-1 monkey kidney cells expressing either H-Ras-Val 12-CVLS or H-Ras-Val12. | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079083![]() (1-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-be...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Effect on Ras processing in Cos-1 monkey kidney cells expressing either H-Ras-Val 12-CVLS or H-Ras-Val12. | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079071![]() (4-{2-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of [3H]-FPP incorporation into His6-H-Ras-CVLS by farnesyl transferase | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079078![]() ((R)-2-Amino-1-(4-{2-[4-((R)-3,10-dibromo-8-chloro-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Hras Farnesyltransferase (FPT). | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079074![]() (4-{2-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Effect on Ras processing in Cos-1 monkey kidney cells expressing either H-Ras-Val 12-CVLS or H-Ras-Val12. | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079071![]() (4-{2-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Effect on Ras processing in Cos-1 monkey kidney cells expressing either H-Ras-Val 12-CVLS or H-Ras-Val12. | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079088![]() (1-(4-{2-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Effect on Ras processing in Cos-1 monkey kidney cells expressing either H-Ras-Val 12-CVLS or H-Ras-Val12. | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079070![]() (1-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-be...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Effect on Ras processing in Cos-1 monkey kidney cells expressing either H-Ras-Val 12-CVLS or H-Ras-Val12. | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM14459![]() ((+)-4-[2-[4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Effect on Ras processing in Cos-1 monkey kidney cells expressing either H-Ras-Val 12-CVLS or H-Ras-Val12. | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079073![]() (2-(4-{2-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Effect on Ras processing in Cos-1 monkey kidney cells expressing either H-Ras-Val 12-CVLS or H-Ras-Val12. | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079082![]() (1-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-be...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 17.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Hras Farnesyltransferase (FPT). | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079076![]() (5-(4-{2-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Effect on Ras processing in Cos-1 monkey kidney cells expressing either H-Ras-Val 12-CVLS or H-Ras-Val12. | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079084![]() (CHEMBL432573 | [(4-{2-[4-((R)-3,10-Dibromo-8-chlor...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Effect on Ras processing in Cos-1 monkey kidney cells expressing either H-Ras-Val 12-CVLS or H-Ras-Val12. | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079075![]() (4-{2-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Effect on Ras processing in Cos-1 monkey kidney cells expressing either H-Ras-Val 12-CVLS or H-Ras-Val12. | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079080![]() (1-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-be...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Effect on Ras processing in Cos-1 monkey kidney cells expressing either H-Ras-Val 12-CVLS or H-Ras-Val12. | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079089![]() (1-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-be...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Effect on Ras processing in Cos-1 monkey kidney cells expressing either H-Ras-Val 12-CVLS or H-Ras-Val12. | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079087![]() (2-[1-(2-Amino-acetyl)-piperidin-4-yl]-1-[4-((R)-3,...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Effect on Ras processing in Cos-1 monkey kidney cells expressing either H-Ras-Val 12-CVLS or H-Ras-Val12. | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079072![]() (4-{2-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Effect on Ras processing in Cos-1 monkey kidney cells expressing either H-Ras-Val 12-CVLS or H-Ras-Val12. | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079078![]() ((R)-2-Amino-1-(4-{2-[4-((R)-3,10-dibromo-8-chloro-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Effect on Ras processing in Cos-1 monkey kidney cells expressing either H-Ras-Val 12-CVLS or H-Ras-Val12. | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079081![]() (2-(4-{2-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Effect on Ras processing in Cos-1 monkey kidney cells expressing either H-Ras-Val 12-CVLS or H-Ras-Val12. | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079093![]() (2-(1-Benzenesulfonyl-piperidin-4-yl)-1-[4-((R)-3,1...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 76.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Hras Farnesyltransferase (FPT). | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079092![]() ((S)-2-Amino-1-(4-{2-[4-((R)-3,10-dibromo-8-chloro-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Effect on Ras processing in Cos-1 monkey kidney cells expressing either H-Ras-Val 12-CVLS or H-Ras-Val12. | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079082![]() (1-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-be...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Effect on Ras processing in Cos-1 monkey kidney cells expressing either H-Ras-Val 12-CVLS or H-Ras-Val12. | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079090![]() (CHEMBL90435 | [(4-{2-[4-((R)-3,10-Dibromo-8-chloro...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Effect on Ras processing in Cos-1 monkey kidney cells expressing either H-Ras-Val 12-CVLS or H-Ras-Val12. | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50079085![]() (5-(4-{2-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Effect on Ras processing in Cos-1 monkey kidney cells expressing either H-Ras-Val 12-CVLS or H-Ras-Val12. | J Med Chem 42: 2651-61 (1999) Article DOI: 10.1021/jm990059k BindingDB Entry DOI: 10.7270/Q2ST7P2V | |||||||||||
More data for this Ligand-Target Pair |