Compile Data Set for Download or QSAR

Found 48 hits Enz. Inhib. hit(s) with all data for entry = 50009158   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase ROS (Homo sapiens (Human))	BDBM50525830 (CHEMBL4562805) Show SMILES COc1cc(NC(=O)N2CCOCC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 Show InChI InChI=1S/C24H26ClN7O4/c1-15(33)27-18-5-3-4-6-19(18)29-22-17(25)14-26-23(31-22)30-20-8-7-16(13-21(20)35-2)28-24(34)32-9-11-36-12-10-32/h3-8,13-14H,9-12H2,1-2H3,(H,27,33)(H,28,34)(H2,26,29,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.730	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ROS (1883 to 2347 residues) cytoplasmic domain expressed in baculovirus expression system using...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50525830 (CHEMBL4562805) Show SMILES COc1cc(NC(=O)N2CCOCC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 Show InChI InChI=1S/C24H26ClN7O4/c1-15(33)27-18-5-3-4-6-19(18)29-22-17(25)14-26-23(31-22)30-20-8-7-16(13-21(20)35-2)28-24(34)32-9-11-36-12-10-32/h3-8,13-14H,9-12H2,1-2H3,(H,27,33)(H,28,34)(H2,26,29,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.910	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ALK (1058 to 1620 residues) cytoplasmic domain L1196M mutant expressed in baculovirus expressio...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase ROS (Homo sapiens (Human))	BDBM50525834 (CHEMBL4448400) Show SMILES COc1cc(NC(=O)N2CCCC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 Show InChI InChI=1S/C24H26ClN7O3/c1-15(33)27-18-7-3-4-8-19(18)29-22-17(25)14-26-23(31-22)30-20-10-9-16(13-21(20)35-2)28-24(34)32-11-5-6-12-32/h3-4,7-10,13-14H,5-6,11-12H2,1-2H3,(H,27,33)(H,28,34)(H2,26,29,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.970	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ROS (1883 to 2347 residues) cytoplasmic domain expressed in baculovirus expression system using...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase ROS (Homo sapiens (Human))	BDBM50525831 (CHEMBL4468370) Show SMILES COc1cc(NC(=O)N2CCN(CCO)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 Show InChI InChI=1S/C26H31ClN8O4/c1-17(37)29-20-5-3-4-6-21(20)31-24-19(27)16-28-25(33-24)32-22-8-7-18(15-23(22)39-2)30-26(38)35-11-9-34(10-12-35)13-14-36/h3-8,15-16,36H,9-14H2,1-2H3,(H,29,37)(H,30,38)(H2,28,31,32,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ROS (1883 to 2347 residues) cytoplasmic domain expressed in baculovirus expression system using...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50525830 (CHEMBL4562805) Show SMILES COc1cc(NC(=O)N2CCOCC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 Show InChI InChI=1S/C24H26ClN7O4/c1-15(33)27-18-5-3-4-6-19(18)29-22-17(25)14-26-23(31-22)30-20-8-7-16(13-21(20)35-2)28-24(34)32-9-11-36-12-10-32/h3-8,13-14H,9-12H2,1-2H3,(H,27,33)(H,28,34)(H2,26,29,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ALK (1058 to 1620 residues) cytoplasmic domain expressed in baculovirus expression system using...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50525829 (CHEMBL4546844) Show SMILES COc1cc(NC(=O)NC2CCC(=O)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 Show InChI InChI=1S/C26H28ClN7O4/c1-15(35)29-20-5-3-4-6-21(20)32-24-19(27)14-28-25(34-24)33-22-12-9-17(13-23(22)38-2)31-26(37)30-16-7-10-18(36)11-8-16/h3-6,9,12-14,16H,7-8,10-11H2,1-2H3,(H,29,35)(H2,30,31,37)(H2,28,32,33,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ALK (1058 to 1620 residues) cytoplasmic domain expressed in baculovirus expression system using...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50525831 (CHEMBL4468370) Show SMILES COc1cc(NC(=O)N2CCN(CCO)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 Show InChI InChI=1S/C26H31ClN8O4/c1-17(37)29-20-5-3-4-6-21(20)31-24-19(27)16-28-25(33-24)32-22-8-7-18(15-23(22)39-2)30-26(38)35-11-9-34(10-12-35)13-14-36/h3-8,15-16,36H,9-14H2,1-2H3,(H,29,37)(H,30,38)(H2,28,31,32,33)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ALK (1058 to 1620 residues) cytoplasmic domain L1196M mutant expressed in baculovirus expressio...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50436850 (CERITINIB | CHEMBL2403108 | LDK378 | US10053458, C...) Show SMILES CC(C)Oc1cc(C2CCNCC2)c(C)cc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 Show InChI InChI=1S/C28H36ClN5O3S/c1-17(2)37-25-15-21(20-10-12-30-13-11-20)19(5)14-24(25)33-28-31-16-22(29)27(34-28)32-23-8-6-7-9-26(23)38(35,36)18(3)4/h6-9,14-18,20,30H,10-13H2,1-5H3,(H2,31,32,33,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ALK (1058 to 1620 residues) cytoplasmic domain expressed in baculovirus expression system using...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair				3D Structure (crystal)
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50525832 (CHEMBL4471142) Show SMILES COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1)N1CCCC1=O Show InChI InChI=1S/C23H23ClN6O3/c1-14(31)26-17-6-3-4-7-18(17)27-22-16(24)13-25-23(29-22)28-19-10-9-15(12-20(19)33-2)30-11-5-8-21(30)32/h3-4,6-7,9-10,12-13H,5,8,11H2,1-2H3,(H,26,31)(H2,25,27,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ALK (1058 to 1620 residues) cytoplasmic domain L1196M mutant expressed in baculovirus expressio...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50436850 (CERITINIB | CHEMBL2403108 | LDK378 | US10053458, C...) Show SMILES CC(C)Oc1cc(C2CCNCC2)c(C)cc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 Show InChI InChI=1S/C28H36ClN5O3S/c1-17(2)37-25-15-21(20-10-12-30-13-11-20)19(5)14-24(25)33-28-31-16-22(29)27(34-28)32-23-8-6-7-9-26(23)38(35,36)18(3)4/h6-9,14-18,20,30H,10-13H2,1-5H3,(H2,31,32,33,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ALK (1058 to 1620 residues) cytoplasmic domain L1196M mutant expressed in baculovirus expressio...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Proto-oncogene tyrosine-protein kinase ROS (Homo sapiens (Human))	BDBM50525828 (CHEMBL4462528) Show SMILES COc1cc(NC(=O)C2CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 Show InChI InChI=1S/C23H23ClN6O3/c1-13(31)26-17-5-3-4-6-18(17)28-21-16(24)12-25-23(30-21)29-19-10-9-15(11-20(19)33-2)27-22(32)14-7-8-14/h3-6,9-12,14H,7-8H2,1-2H3,(H,26,31)(H,27,32)(H2,25,28,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ROS (1883 to 2347 residues) cytoplasmic domain expressed in baculovirus expression system using...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase ROS (Homo sapiens (Human))	BDBM50525829 (CHEMBL4546844) Show SMILES COc1cc(NC(=O)NC2CCC(=O)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 Show InChI InChI=1S/C26H28ClN7O4/c1-15(35)29-20-5-3-4-6-21(20)32-24-19(27)14-28-25(34-24)33-22-12-9-17(13-23(22)38-2)31-26(37)30-16-7-10-18(36)11-8-16/h3-6,9,12-14,16H,7-8,10-11H2,1-2H3,(H,29,35)(H2,30,31,37)(H2,28,32,33,34)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ROS (1883 to 2347 residues) cytoplasmic domain expressed in baculovirus expression system using...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50525834 (CHEMBL4448400) Show SMILES COc1cc(NC(=O)N2CCCC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 Show InChI InChI=1S/C24H26ClN7O3/c1-15(33)27-18-7-3-4-8-19(18)29-22-17(25)14-26-23(31-22)30-20-10-9-16(13-21(20)35-2)28-24(34)32-11-5-6-12-32/h3-4,7-10,13-14H,5-6,11-12H2,1-2H3,(H,27,33)(H,28,34)(H2,26,29,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ALK (1058 to 1620 residues) cytoplasmic domain L1196M mutant expressed in baculovirus expressio...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50525829 (CHEMBL4546844) Show SMILES COc1cc(NC(=O)NC2CCC(=O)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 Show InChI InChI=1S/C26H28ClN7O4/c1-15(35)29-20-5-3-4-6-21(20)32-24-19(27)14-28-25(34-24)33-22-12-9-17(13-23(22)38-2)31-26(37)30-16-7-10-18(36)11-8-16/h3-6,9,12-14,16H,7-8,10-11H2,1-2H3,(H,29,35)(H2,30,31,37)(H2,28,32,33,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ALK (1058 to 1620 residues) cytoplasmic domain L1196M mutant expressed in baculovirus expressio...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50525828 (CHEMBL4462528) Show SMILES COc1cc(NC(=O)C2CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 Show InChI InChI=1S/C23H23ClN6O3/c1-13(31)26-17-5-3-4-6-18(17)28-21-16(24)12-25-23(30-21)29-19-10-9-15(11-20(19)33-2)27-22(32)14-7-8-14/h3-6,9-12,14H,7-8H2,1-2H3,(H,26,31)(H,27,32)(H2,25,28,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ALK (1058 to 1620 residues) cytoplasmic domain expressed in baculovirus expression system using...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50525830 (CHEMBL4562805) Show SMILES COc1cc(NC(=O)N2CCOCC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 Show InChI InChI=1S/C24H26ClN7O4/c1-15(33)27-18-5-3-4-6-19(18)29-22-17(25)14-26-23(31-22)30-20-8-7-16(13-21(20)35-2)28-24(34)32-9-11-36-12-10-32/h3-8,13-14H,9-12H2,1-2H3,(H,27,33)(H,28,34)(H2,26,29,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ALK (1058 to 1620 residues) cytoplasmic domain G1202R mutant using srctide as substrate incubat...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase ROS (Homo sapiens (Human))	BDBM50436850 (CERITINIB | CHEMBL2403108 | LDK378 | US10053458, C...) Show SMILES CC(C)Oc1cc(C2CCNCC2)c(C)cc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 Show InChI InChI=1S/C28H36ClN5O3S/c1-17(2)37-25-15-21(20-10-12-30-13-11-20)19(5)14-24(25)33-28-31-16-22(29)27(34-28)32-23-8-6-7-9-26(23)38(35,36)18(3)4/h6-9,14-18,20,30H,10-13H2,1-5H3,(H2,31,32,33,34)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ROS (1883 to 2347 residues) cytoplasmic domain expressed in baculovirus expression system using...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase ROS (Homo sapiens (Human))	BDBM50525832 (CHEMBL4471142) Show SMILES COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1)N1CCCC1=O Show InChI InChI=1S/C23H23ClN6O3/c1-14(31)26-17-6-3-4-7-18(17)27-22-16(24)13-25-23(29-22)28-19-10-9-15(12-20(19)33-2)30-11-5-8-21(30)32/h3-4,6-7,9-10,12-13H,5,8,11H2,1-2H3,(H,26,31)(H2,25,27,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ROS (1883 to 2347 residues) cytoplasmic domain expressed in baculovirus expression system using...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50525833 (CHEMBL4536955) Show SMILES COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1)N1CCCNC1=O Show InChI InChI=1S/C23H24ClN7O3/c1-14(32)27-17-6-3-4-7-18(17)28-21-16(24)13-26-22(30-21)29-19-9-8-15(12-20(19)34-2)31-11-5-10-25-23(31)33/h3-4,6-9,12-13H,5,10-11H2,1-2H3,(H,25,33)(H,27,32)(H2,26,28,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ALK (1058 to 1620 residues) cytoplasmic domain expressed in baculovirus expression system using...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50525833 (CHEMBL4536955) Show SMILES COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1)N1CCCNC1=O Show InChI InChI=1S/C23H24ClN7O3/c1-14(32)27-17-6-3-4-7-18(17)28-21-16(24)13-26-22(30-21)29-19-9-8-15(12-20(19)34-2)31-11-5-10-25-23(31)33/h3-4,6-9,12-13H,5,10-11H2,1-2H3,(H,25,33)(H,27,32)(H2,26,28,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ALK (1058 to 1620 residues) cytoplasmic domain L1196M mutant expressed in baculovirus expressio...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50525834 (CHEMBL4448400) Show SMILES COc1cc(NC(=O)N2CCCC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 Show InChI InChI=1S/C24H26ClN7O3/c1-15(33)27-18-7-3-4-8-19(18)29-22-17(25)14-26-23(31-22)30-20-10-9-16(13-21(20)35-2)28-24(34)32-11-5-6-12-32/h3-4,7-10,13-14H,5-6,11-12H2,1-2H3,(H,27,33)(H,28,34)(H2,26,29,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ALK (1058 to 1620 residues) cytoplasmic domain expressed in baculovirus expression system using...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase ROS (Homo sapiens (Human))	BDBM50525833 (CHEMBL4536955) Show SMILES COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1)N1CCCNC1=O Show InChI InChI=1S/C23H24ClN7O3/c1-14(32)27-17-6-3-4-7-18(17)28-21-16(24)13-26-22(30-21)29-19-9-8-15(12-20(19)34-2)31-11-5-10-25-23(31)33/h3-4,6-9,12-13H,5,10-11H2,1-2H3,(H,25,33)(H,27,32)(H2,26,28,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ROS (1883 to 2347 residues) cytoplasmic domain expressed in baculovirus expression system using...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50525832 (CHEMBL4471142) Show SMILES COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1)N1CCCC1=O Show InChI InChI=1S/C23H23ClN6O3/c1-14(31)26-17-6-3-4-7-18(17)27-22-16(24)13-25-23(29-22)28-19-10-9-15(12-20(19)33-2)30-11-5-8-21(30)32/h3-4,6-7,9-10,12-13H,5,8,11H2,1-2H3,(H,26,31)(H2,25,27,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ALK (1058 to 1620 residues) cytoplasmic domain expressed in baculovirus expression system using...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50525831 (CHEMBL4468370) Show SMILES COc1cc(NC(=O)N2CCN(CCO)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 Show InChI InChI=1S/C26H31ClN8O4/c1-17(37)29-20-5-3-4-6-21(20)31-24-19(27)16-28-25(33-24)32-22-8-7-18(15-23(22)39-2)30-26(38)35-11-9-34(10-12-35)13-14-36/h3-8,15-16,36H,9-14H2,1-2H3,(H,29,37)(H,30,38)(H2,28,31,32,33)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ALK (1058 to 1620 residues) cytoplasmic domain expressed in baculovirus expression system using...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50525831 (CHEMBL4468370) Show SMILES COc1cc(NC(=O)N2CCN(CCO)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 Show InChI InChI=1S/C26H31ClN8O4/c1-17(37)29-20-5-3-4-6-21(20)31-24-19(27)16-28-25(33-24)32-22-8-7-18(15-23(22)39-2)30-26(38)35-11-9-34(10-12-35)13-14-36/h3-8,15-16,36H,9-14H2,1-2H3,(H,29,37)(H,30,38)(H2,28,31,32,33)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ALK (1058 to 1620 residues) cytoplasmic domain G1202R mutant using srctide as substrate incubat...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50525828 (CHEMBL4462528) Show SMILES COc1cc(NC(=O)C2CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 Show InChI InChI=1S/C23H23ClN6O3/c1-13(31)26-17-5-3-4-6-18(17)28-21-16(24)12-25-23(30-21)29-19-10-9-15(11-20(19)33-2)27-22(32)14-7-8-14/h3-6,9-12,14H,7-8H2,1-2H3,(H,26,31)(H,27,32)(H2,25,28,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ALK (1058 to 1620 residues) cytoplasmic domain L1196M mutant expressed in baculovirus expressio...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50525834 (CHEMBL4448400) Show SMILES COc1cc(NC(=O)N2CCCC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 Show InChI InChI=1S/C24H26ClN7O3/c1-15(33)27-18-7-3-4-8-19(18)29-22-17(25)14-26-23(31-22)30-20-10-9-16(13-21(20)35-2)28-24(34)32-11-5-6-12-32/h3-4,7-10,13-14H,5-6,11-12H2,1-2H3,(H,27,33)(H,28,34)(H2,26,29,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ALK (1058 to 1620 residues) cytoplasmic domain G1202R mutant using srctide as substrate incubat...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50525829 (CHEMBL4546844) Show SMILES COc1cc(NC(=O)NC2CCC(=O)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 Show InChI InChI=1S/C26H28ClN7O4/c1-15(35)29-20-5-3-4-6-21(20)32-24-19(27)14-28-25(34-24)33-22-12-9-17(13-23(22)38-2)31-26(37)30-16-7-10-18(36)11-8-16/h3-6,9,12-14,16H,7-8,10-11H2,1-2H3,(H,29,35)(H2,30,31,37)(H2,28,32,33,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ALK (1058 to 1620 residues) cytoplasmic domain G1202R mutant using srctide as substrate incubat...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50525833 (CHEMBL4536955) Show SMILES COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1)N1CCCNC1=O Show InChI InChI=1S/C23H24ClN7O3/c1-14(32)27-17-6-3-4-7-18(17)28-21-16(24)13-26-22(30-21)29-19-9-8-15(12-20(19)34-2)31-11-5-10-25-23(31)33/h3-4,6-9,12-13H,5,10-11H2,1-2H3,(H,25,33)(H,27,32)(H2,26,28,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ALK (1058 to 1620 residues) cytoplasmic domain G1202R mutant using srctide as substrate incubat...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50525828 (CHEMBL4462528) Show SMILES COc1cc(NC(=O)C2CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 Show InChI InChI=1S/C23H23ClN6O3/c1-13(31)26-17-5-3-4-6-18(17)28-21-16(24)12-25-23(30-21)29-19-10-9-15(11-20(19)33-2)27-22(32)14-7-8-14/h3-6,9-12,14H,7-8H2,1-2H3,(H,26,31)(H,27,32)(H2,25,28,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ALK (1058 to 1620 residues) cytoplasmic domain G1202R mutant using srctide as substrate incubat...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50525832 (CHEMBL4471142) Show SMILES COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1)N1CCCC1=O Show InChI InChI=1S/C23H23ClN6O3/c1-14(31)26-17-6-3-4-7-18(17)27-22-16(24)13-25-23(29-22)28-19-10-9-15(12-20(19)33-2)30-11-5-8-21(30)32/h3-4,6-7,9-10,12-13H,5,8,11H2,1-2H3,(H,26,31)(H2,25,27,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ALK (1058 to 1620 residues) cytoplasmic domain G1202R mutant using srctide as substrate incubat...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50436850 (CERITINIB | CHEMBL2403108 | LDK378 | US10053458, C...) Show SMILES CC(C)Oc1cc(C2CCNCC2)c(C)cc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 Show InChI InChI=1S/C28H36ClN5O3S/c1-17(2)37-25-15-21(20-10-12-30-13-11-20)19(5)14-24(25)33-28-31-16-22(29)27(34-28)32-23-8-6-7-9-26(23)38(35,36)18(3)4/h6-9,14-18,20,30H,10-13H2,1-5H3,(H2,31,32,33,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	197	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ALK (1058 to 1620 residues) cytoplasmic domain G1202R mutant using srctide as substrate incubat...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50436850 (CERITINIB | CHEMBL2403108 | LDK378 | US10053458, C...) Show SMILES CC(C)Oc1cc(C2CCNCC2)c(C)cc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 Show InChI InChI=1S/C28H36ClN5O3S/c1-17(2)37-25-15-21(20-10-12-30-13-11-20)19(5)14-24(25)33-28-31-16-22(29)27(34-28)32-23-8-6-7-9-26(23)38(35,36)18(3)4/h6-9,14-18,20,30H,10-13H2,1-5H3,(H2,31,32,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	271	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged MET (956 to 1390 residues) cytoplasmic domain expressed in baculovirus expression system using ...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50525829 (CHEMBL4546844) Show SMILES COc1cc(NC(=O)NC2CCC(=O)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 Show InChI InChI=1S/C26H28ClN7O4/c1-15(35)29-20-5-3-4-6-21(20)32-24-19(27)14-28-25(34-24)33-22-12-9-17(13-23(22)38-2)31-26(37)30-16-7-10-18(36)11-8-16/h3-6,9,12-14,16H,7-8,10-11H2,1-2H3,(H,29,35)(H2,30,31,37)(H2,28,32,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	325	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged MET (956 to 1390 residues) cytoplasmic domain expressed in baculovirus expression system using ...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50525832 (CHEMBL4471142) Show SMILES COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1)N1CCCC1=O Show InChI InChI=1S/C23H23ClN6O3/c1-14(31)26-17-6-3-4-7-18(17)27-22-16(24)13-25-23(29-22)28-19-10-9-15(12-20(19)33-2)30-11-5-8-21(30)32/h3-4,6-7,9-10,12-13H,5,8,11H2,1-2H3,(H,26,31)(H2,25,27,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	532	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged MET (956 to 1390 residues) cytoplasmic domain expressed in baculovirus expression system using ...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50525828 (CHEMBL4462528) Show SMILES COc1cc(NC(=O)C2CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 Show InChI InChI=1S/C23H23ClN6O3/c1-13(31)26-17-5-3-4-6-18(17)28-21-16(24)12-25-23(30-21)29-19-10-9-15(11-20(19)33-2)27-22(32)14-7-8-14/h3-6,9-12,14H,7-8H2,1-2H3,(H,26,31)(H,27,32)(H2,25,28,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	617	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged EGFR (669 to 1210 residues) cytoplasmic domain expressed in baculovirus expression system using...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50525834 (CHEMBL4448400) Show SMILES COc1cc(NC(=O)N2CCCC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 Show InChI InChI=1S/C24H26ClN7O3/c1-15(33)27-18-7-3-4-8-19(18)29-22-17(25)14-26-23(31-22)30-20-10-9-16(13-21(20)35-2)28-24(34)32-11-5-6-12-32/h3-4,7-10,13-14H,5-6,11-12H2,1-2H3,(H,27,33)(H,28,34)(H2,26,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged MET (956 to 1390 residues) cytoplasmic domain expressed in baculovirus expression system using ...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50525828 (CHEMBL4462528) Show SMILES COc1cc(NC(=O)C2CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 Show InChI InChI=1S/C23H23ClN6O3/c1-13(31)26-17-5-3-4-6-18(17)28-21-16(24)12-25-23(30-21)29-19-10-9-15(11-20(19)33-2)27-22(32)14-7-8-14/h3-6,9-12,14H,7-8H2,1-2H3,(H,26,31)(H,27,32)(H2,25,28,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged MET (956 to 1390 residues) cytoplasmic domain expressed in baculovirus expression system using ...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50525830 (CHEMBL4562805) Show SMILES COc1cc(NC(=O)N2CCOCC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 Show InChI InChI=1S/C24H26ClN7O4/c1-15(33)27-18-5-3-4-6-19(18)29-22-17(25)14-26-23(31-22)30-20-8-7-16(13-21(20)35-2)28-24(34)32-9-11-36-12-10-32/h3-8,13-14H,9-12H2,1-2H3,(H,27,33)(H,28,34)(H2,26,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged EGFR (669 to 1210 residues) cytoplasmic domain expressed in baculovirus expression system using...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50525834 (CHEMBL4448400) Show SMILES COc1cc(NC(=O)N2CCCC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 Show InChI InChI=1S/C24H26ClN7O3/c1-15(33)27-18-7-3-4-8-19(18)29-22-17(25)14-26-23(31-22)30-20-10-9-16(13-21(20)35-2)28-24(34)32-11-5-6-12-32/h3-4,7-10,13-14H,5-6,11-12H2,1-2H3,(H,27,33)(H,28,34)(H2,26,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged EGFR (669 to 1210 residues) cytoplasmic domain expressed in baculovirus expression system using...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50436850 (CERITINIB | CHEMBL2403108 | LDK378 | US10053458, C...) Show SMILES CC(C)Oc1cc(C2CCNCC2)c(C)cc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 Show InChI InChI=1S/C28H36ClN5O3S/c1-17(2)37-25-15-21(20-10-12-30-13-11-20)19(5)14-24(25)33-28-31-16-22(29)27(34-28)32-23-8-6-7-9-26(23)38(35,36)18(3)4/h6-9,14-18,20,30H,10-13H2,1-5H3,(H2,31,32,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged EGFR (669 to 1210 residues) cytoplasmic domain expressed in baculovirus expression system using...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50525833 (CHEMBL4536955) Show SMILES COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1)N1CCCNC1=O Show InChI InChI=1S/C23H24ClN7O3/c1-14(32)27-17-6-3-4-7-18(17)28-21-16(24)13-26-22(30-21)29-19-9-8-15(12-20(19)34-2)31-11-5-10-25-23(31)33/h3-4,6-9,12-13H,5,10-11H2,1-2H3,(H,25,33)(H,27,32)(H2,26,28,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged MET (956 to 1390 residues) cytoplasmic domain expressed in baculovirus expression system using ...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50525832 (CHEMBL4471142) Show SMILES COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1)N1CCCC1=O Show InChI InChI=1S/C23H23ClN6O3/c1-14(31)26-17-6-3-4-7-18(17)27-22-16(24)13-25-23(29-22)28-19-10-9-15(12-20(19)33-2)30-11-5-8-21(30)32/h3-4,6-7,9-10,12-13H,5,8,11H2,1-2H3,(H,26,31)(H2,25,27,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged EGFR (669 to 1210 residues) cytoplasmic domain expressed in baculovirus expression system using...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50525830 (CHEMBL4562805) Show SMILES COc1cc(NC(=O)N2CCOCC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 Show InChI InChI=1S/C24H26ClN7O4/c1-15(33)27-18-5-3-4-6-19(18)29-22-17(25)14-26-23(31-22)30-20-8-7-16(13-21(20)35-2)28-24(34)32-9-11-36-12-10-32/h3-8,13-14H,9-12H2,1-2H3,(H,27,33)(H,28,34)(H2,26,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged MET (956 to 1390 residues) cytoplasmic domain expressed in baculovirus expression system using ...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50525829 (CHEMBL4546844) Show SMILES COc1cc(NC(=O)NC2CCC(=O)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 Show InChI InChI=1S/C26H28ClN7O4/c1-15(35)29-20-5-3-4-6-21(20)32-24-19(27)14-28-25(34-24)33-22-12-9-17(13-23(22)38-2)31-26(37)30-16-7-10-18(36)11-8-16/h3-6,9,12-14,16H,7-8,10-11H2,1-2H3,(H,29,35)(H2,30,31,37)(H2,28,32,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged EGFR (669 to 1210 residues) cytoplasmic domain expressed in baculovirus expression system using...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50525831 (CHEMBL4468370) Show SMILES COc1cc(NC(=O)N2CCN(CCO)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 Show InChI InChI=1S/C26H31ClN8O4/c1-17(37)29-20-5-3-4-6-21(20)31-24-19(27)16-28-25(33-24)32-22-8-7-18(15-23(22)39-2)30-26(38)35-11-9-34(10-12-35)13-14-36/h3-8,15-16,36H,9-14H2,1-2H3,(H,29,37)(H,30,38)(H2,28,31,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged EGFR (669 to 1210 residues) cytoplasmic domain expressed in baculovirus expression system using...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50525831 (CHEMBL4468370) Show SMILES COc1cc(NC(=O)N2CCN(CCO)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 Show InChI InChI=1S/C26H31ClN8O4/c1-17(37)29-20-5-3-4-6-21(20)31-24-19(27)16-28-25(33-24)32-22-8-7-18(15-23(22)39-2)30-26(38)35-11-9-34(10-12-35)13-14-36/h3-8,15-16,36H,9-14H2,1-2H3,(H,29,37)(H,30,38)(H2,28,31,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged MET (956 to 1390 residues) cytoplasmic domain expressed in baculovirus expression system using ...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50525833 (CHEMBL4536955) Show SMILES COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1)N1CCCNC1=O Show InChI InChI=1S/C23H24ClN7O3/c1-14(32)27-17-6-3-4-7-18(17)28-21-16(24)13-26-22(30-21)29-19-9-8-15(12-20(19)34-2)31-11-5-10-25-23(31)33/h3-4,6-9,12-13H,5,10-11H2,1-2H3,(H,25,33)(H,27,32)(H2,26,28,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged EGFR (669 to 1210 residues) cytoplasmic domain expressed in baculovirus expression system using...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair