Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'ALK tyrosine kinase receptor' and Ligand = 'BDBM50525832'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50525832 (CHEMBL4471142) Show SMILES COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1)N1CCCC1=O Show InChI InChI=1S/C23H23ClN6O3/c1-14(31)26-17-6-3-4-7-18(17)27-22-16(24)13-25-23(29-22)28-19-10-9-15(12-20(19)33-2)30-11-5-8-21(30)32/h3-4,6-7,9-10,12-13H,5,8,11H2,1-2H3,(H,26,31)(H2,25,27,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ALK (1058 to 1620 residues) cytoplasmic domain L1196M mutant expressed in baculovirus expressio...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50525832 (CHEMBL4471142) Show SMILES COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1)N1CCCC1=O Show InChI InChI=1S/C23H23ClN6O3/c1-14(31)26-17-6-3-4-7-18(17)27-22-16(24)13-25-23(29-22)28-19-10-9-15(12-20(19)33-2)30-11-5-8-21(30)32/h3-4,6-7,9-10,12-13H,5,8,11H2,1-2H3,(H,26,31)(H2,25,27,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ALK (1058 to 1620 residues) cytoplasmic domain expressed in baculovirus expression system using...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50525832 (CHEMBL4471142) Show SMILES COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1)N1CCCC1=O Show InChI InChI=1S/C23H23ClN6O3/c1-14(31)26-17-6-3-4-7-18(17)27-22-16(24)13-25-23(29-22)28-19-10-9-15(12-20(19)33-2)30-11-5-8-21(30)32/h3-4,6-7,9-10,12-13H,5,8,11H2,1-2H3,(H,26,31)(H2,25,27,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ALK (1058 to 1620 residues) cytoplasmic domain G1202R mutant using srctide as substrate incubat...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115051 BindingDB Entry DOI: 10.7270/Q2XP78CS
					More data for this Ligand-Target Pair