Compile Data Set for Download or QSAR

Found 68 hits Enz. Inhib. hit(s) with all data for entry = 50009847   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301297 (2-benzyl-6,7,8,9-tetrahydro-2H-pyridazino[4,3-d]az...) Show SMILES O=c1cc2CCNCCc2nn1Cc1ccccc1 Show InChI InChI=1S/C15H17N3O/c19-15-10-13-6-8-16-9-7-14(13)17-18(15)11-12-4-2-1-3-5-12/h1-5,10,16H,6-9,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-mesulergine from recombinant human 5-HT2C receptor transfected in Swiss mouse 3T3 cells after 150 mins by scintillation proximit...				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301297 (2-benzyl-6,7,8,9-tetrahydro-2H-pyridazino[4,3-d]az...) Show SMILES O=c1cc2CCNCCc2nn1Cc1ccccc1 Show InChI InChI=1S/C15H17N3O/c19-15-10-13-6-8-16-9-7-14(13)17-18(15)11-12-4-2-1-3-5-12/h1-5,10,16H,6-9,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-mesulergine from recombinant human 5-HT2C receptor transfected in Swiss mouse 3T3 cells after 150 mins by scintillation proximit...				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532828 (CHEMBL4460600) Show SMILES C(c1ccccc1)c1cc2CCNCCc2nn1 Show InChI InChI=1S/C15H17N3/c1-2-4-12(5-3-1)10-14-11-13-6-8-16-9-7-15(13)18-17-14/h1-5,11,16H,6-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-mesulergine from recombinant human 5-HT2C receptor transfected in Swiss mouse 3T3 cells after 150 mins by scintillation proximit...				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532828 (CHEMBL4460600) Show SMILES C(c1ccccc1)c1cc2CCNCCc2nn1 Show InChI InChI=1S/C15H17N3/c1-2-4-12(5-3-1)10-14-11-13-6-8-16-9-7-15(13)18-17-14/h1-5,11,16H,6-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-mesulergine from recombinant human 5-HT2C receptor transfected in Swiss mouse 3T3 cells after 150 mins by scintillation proximit...				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532829 (CHEMBL4571336) Show SMILES O=c1[nH]c2CCNCCc2nc1Cc1ccccc1 Show InChI InChI=1S/C15H17N3O/c19-15-14(10-11-4-2-1-3-5-11)17-12-6-8-16-9-7-13(12)18-15/h1-5,16H,6-10H2,(H,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-mesulergine from recombinant human 5-HT2C receptor transfected in Swiss mouse 3T3 cells after 150 mins by scintillation proximit...				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532829 (CHEMBL4571336) Show SMILES O=c1[nH]c2CCNCCc2nc1Cc1ccccc1 Show InChI InChI=1S/C15H17N3O/c19-15-14(10-11-4-2-1-3-5-11)17-12-6-8-16-9-7-13(12)18-15/h1-5,16H,6-10H2,(H,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-mesulergine from recombinant human 5-HT2C receptor transfected in Swiss mouse 3T3 cells after 150 mins by scintillation proximit...				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532827 (CHEMBL4571641) Show SMILES Clc1ccc(Cc2cc3CCNCCc3nn2)cc1 Show InChI InChI=1S/C15H16ClN3/c16-13-3-1-11(2-4-13)9-14-10-12-5-7-17-8-6-15(12)19-18-14/h1-4,10,17H,5-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-mesulergine from recombinant human 5-HT2C receptor transfected in Swiss mouse 3T3 cells after 150 mins by scintillation proximit...				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532827 (CHEMBL4571641) Show SMILES Clc1ccc(Cc2cc3CCNCCc3nn2)cc1 Show InChI InChI=1S/C15H16ClN3/c16-13-3-1-11(2-4-13)9-14-10-12-5-7-17-8-6-15(12)19-18-14/h1-4,10,17H,5-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-mesulergine from recombinant human 5-HT2C receptor transfected in Swiss mouse 3T3 cells after 150 mins by scintillation proximit...				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50342538 (2-benzyl-6,7,8,9-tetrahydro-5H-pyrimido[5,4-d]azep...) Show SMILES C(c1ccccc1)c1ncc2CCNCCc2n1 Show InChI InChI=1S/C15H17N3/c1-2-4-12(5-3-1)10-15-17-11-13-6-8-16-9-7-14(13)18-15/h1-5,11,16H,6-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-mesulergine from recombinant human 5-HT2C receptor transfected in Swiss mouse 3T3 cells after 150 mins by scintillation proximit...				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50342538 (2-benzyl-6,7,8,9-tetrahydro-5H-pyrimido[5,4-d]azep...) Show SMILES C(c1ccccc1)c1ncc2CCNCCc2n1 Show InChI InChI=1S/C15H17N3/c1-2-4-12(5-3-1)10-15-17-11-13-6-8-16-9-7-14(13)18-15/h1-5,11,16H,6-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-mesulergine from recombinant human 5-HT2C receptor transfected in Swiss mouse 3T3 cells after 150 mins by scintillation proximit...				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532825 (CHEMBL4437696) Show SMILES CC(c1ccccc1)c1cc2CCNCCc2nn1 Show InChI InChI=1S/C16H19N3/c1-12(13-5-3-2-4-6-13)16-11-14-7-9-17-10-8-15(14)18-19-16/h2-6,11-12,17H,7-10H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-mesulergine from recombinant human 5-HT2C receptor transfected in Swiss mouse 3T3 cells after 150 mins by scintillation proximit...				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532825 (CHEMBL4437696) Show SMILES CC(c1ccccc1)c1cc2CCNCCc2nn1 Show InChI InChI=1S/C16H19N3/c1-12(13-5-3-2-4-6-13)16-11-14-7-9-17-10-8-15(14)18-19-16/h2-6,11-12,17H,7-10H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-mesulergine from recombinant human 5-HT2C receptor transfected in Swiss mouse 3T3 cells after 150 mins by scintillation proximit...				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532831 (CHEMBL4463588) Show SMILES Clc1ccccc1Cc1cc2CCNCCc2nn1 Show InChI InChI=1S/C15H16ClN3/c16-14-4-2-1-3-11(14)9-13-10-12-5-7-17-8-6-15(12)19-18-13/h1-4,10,17H,5-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-mesulergine from recombinant human 5-HT2C receptor transfected in Swiss mouse 3T3 cells after 150 mins by scintillation proximit...				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532825 (CHEMBL4437696) Show SMILES CC(c1ccccc1)c1cc2CCNCCc2nn1 Show InChI InChI=1S/C16H19N3/c1-12(13-5-3-2-4-6-13)16-11-14-7-9-17-10-8-15(14)18-19-16/h2-6,11-12,17H,7-10H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-mesulergine from recombinant human 5-HT2C receptor transfected in Swiss mouse 3T3 cells after 150 mins by scintillation proximit...				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532825 (CHEMBL4437696) Show SMILES CC(c1ccccc1)c1cc2CCNCCc2nn1 Show InChI InChI=1S/C16H19N3/c1-12(13-5-3-2-4-6-13)16-11-14-7-9-17-10-8-15(14)18-19-16/h2-6,11-12,17H,7-10H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-mesulergine from recombinant human 5-HT2C receptor transfected in Swiss mouse 3T3 cells after 150 mins by scintillation proximit...				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532831 (CHEMBL4463588) Show SMILES Clc1ccccc1Cc1cc2CCNCCc2nn1 Show InChI InChI=1S/C15H16ClN3/c16-14-4-2-1-3-11(14)9-13-10-12-5-7-17-8-6-15(12)19-18-13/h1-4,10,17H,5-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-mesulergine from recombinant human 5-HT2C receptor transfected in Swiss mouse 3T3 cells after 150 mins by scintillation proximit...				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532824 (CHEMBL4538660) Show SMILES FC(F)(F)c1cccc(Cc2cc3CCNCCc3nn2)c1 Show InChI InChI=1S/C16H16F3N3/c17-16(18,19)13-3-1-2-11(8-13)9-14-10-12-4-6-20-7-5-15(12)22-21-14/h1-3,8,10,20H,4-7,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-mesulergine from recombinant human 5-HT2C receptor transfected in Swiss mouse 3T3 cells after 150 mins by scintillation proximit...				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532824 (CHEMBL4538660) Show SMILES FC(F)(F)c1cccc(Cc2cc3CCNCCc3nn2)c1 Show InChI InChI=1S/C16H16F3N3/c17-16(18,19)13-3-1-2-11(8-13)9-14-10-12-4-6-20-7-5-15(12)22-21-14/h1-3,8,10,20H,4-7,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-mesulergine from recombinant human 5-HT2C receptor transfected in Swiss mouse 3T3 cells after 150 mins by scintillation proximit...				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532830 (CHEMBL4438673) Show SMILES Fc1ccc(Cc2cc3CCNCCc3nn2)cc1 Show InChI InChI=1S/C15H16FN3/c16-13-3-1-11(2-4-13)9-14-10-12-5-7-17-8-6-15(12)19-18-14/h1-4,10,17H,5-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-mesulergine from recombinant human 5-HT2C receptor transfected in Swiss mouse 3T3 cells after 150 mins by scintillation proximit...				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532830 (CHEMBL4438673) Show SMILES Fc1ccc(Cc2cc3CCNCCc3nn2)cc1 Show InChI InChI=1S/C15H16FN3/c16-13-3-1-11(2-4-13)9-14-10-12-5-7-17-8-6-15(12)19-18-14/h1-4,10,17H,5-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-mesulergine from recombinant human 5-HT2C receptor transfected in Swiss mouse 3T3 cells after 150 mins by scintillation proximit...				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532832 (CHEMBL4514905) Show SMILES Cc1c(Cc2ccccc2)nnc2CCNCCc12 Show InChI InChI=1S/C16H19N3/c1-12-14-7-9-17-10-8-15(14)18-19-16(12)11-13-5-3-2-4-6-13/h2-6,17H,7-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-mesulergine from recombinant human 5-HT2C receptor transfected in Swiss mouse 3T3 cells after 150 mins by scintillation proximit...				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532832 (CHEMBL4514905) Show SMILES Cc1c(Cc2ccccc2)nnc2CCNCCc12 Show InChI InChI=1S/C16H19N3/c1-12-14-7-9-17-10-8-15(14)18-19-16(12)11-13-5-3-2-4-6-13/h2-6,17H,7-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-mesulergine from recombinant human 5-HT2C receptor transfected in Swiss mouse 3T3 cells after 150 mins by scintillation proximit...				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532826 (CHEMBL4450290) Show SMILES COc1ccccc1Cc1cc2CCNCCc2nn1 Show InChI InChI=1S/C16H19N3O/c1-20-16-5-3-2-4-13(16)11-14-10-12-6-8-17-9-7-15(12)19-18-14/h2-5,10,17H,6-9,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	550	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-mesulergine from recombinant human 5-HT2C receptor transfected in Swiss mouse 3T3 cells after 150 mins by scintillation proximit...				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532826 (CHEMBL4450290) Show SMILES COc1ccccc1Cc1cc2CCNCCc2nn1 Show InChI InChI=1S/C16H19N3O/c1-20-16-5-3-2-4-13(16)11-14-10-12-6-8-17-9-7-15(12)19-18-14/h2-5,10,17H,6-9,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	550	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-mesulergine from recombinant human 5-HT2C receptor transfected in Swiss mouse 3T3 cells after 150 mins by scintillation proximit...				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301288 (2-benzyl-2,4,5,6,7,8-hexahydropyrazolo[4,3-d]azepi...) Show SMILES C(c1ccccc1)n1cc2CCNCCc2n1 Show InChI InChI=1S/C14H17N3/c1-2-4-12(5-3-1)10-17-11-13-6-8-15-9-7-14(13)16-17/h1-5,11,15H,6-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-mesulergine from recombinant human 5-HT2C receptor transfected in Swiss mouse 3T3 cells after 150 mins by scintillation proximit...				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301288 (2-benzyl-2,4,5,6,7,8-hexahydropyrazolo[4,3-d]azepi...) Show SMILES C(c1ccccc1)n1cc2CCNCCc2n1 Show InChI InChI=1S/C14H17N3/c1-2-4-12(5-3-1)10-17-11-13-6-8-15-9-7-14(13)16-17/h1-5,11,15H,6-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-mesulergine from recombinant human 5-HT2C receptor transfected in Swiss mouse 3T3 cells after 150 mins by scintillation proximit...				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532823 (CHEMBL4476743) Show SMILES C(c1nnc2CCNCCn12)c1ccccc1 Show InChI InChI=1S/C13H16N4/c1-2-4-11(5-3-1)10-13-16-15-12-6-7-14-8-9-17(12)13/h1-5,14H,6-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-mesulergine from recombinant human 5-HT2C receptor transfected in Swiss mouse 3T3 cells after 150 mins by scintillation proximit...				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532823 (CHEMBL4476743) Show SMILES C(c1nnc2CCNCCn12)c1ccccc1 Show InChI InChI=1S/C13H16N4/c1-2-4-11(5-3-1)10-13-16-15-12-6-7-14-8-9-17(12)13/h1-5,14H,6-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-mesulergine from recombinant human 5-HT2C receptor transfected in Swiss mouse 3T3 cells after 150 mins by scintillation proximit...				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532824 (CHEMBL4538660) Show SMILES FC(F)(F)c1cccc(Cc2cc3CCNCCc3nn2)c1 Show InChI InChI=1S/C16H16F3N3/c17-16(18,19)13-3-1-2-11(8-13)9-14-10-12-4-6-20-7-5-15(12)22-21-14/h1-3,8,10,20H,4-7,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	750	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor transfected in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301297 (2-benzyl-6,7,8,9-tetrahydro-2H-pyridazino[4,3-d]az...) Show SMILES O=c1cc2CCNCCc2nn1Cc1ccccc1 Show InChI InChI=1S/C15H17N3O/c19-15-10-13-6-8-16-9-7-14(13)17-18(15)11-12-4-2-1-3-5-12/h1-5,10,16H,6-9,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor transfected in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532824 (CHEMBL4538660) Show SMILES FC(F)(F)c1cccc(Cc2cc3CCNCCc3nn2)c1 Show InChI InChI=1S/C16H16F3N3/c17-16(18,19)13-3-1-2-11(8-13)9-14-10-12-4-6-20-7-5-15(12)22-21-14/h1-3,8,10,20H,4-7,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	750	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor transfected in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301297 (2-benzyl-6,7,8,9-tetrahydro-2H-pyridazino[4,3-d]az...) Show SMILES O=c1cc2CCNCCc2nn1Cc1ccccc1 Show InChI InChI=1S/C15H17N3O/c19-15-10-13-6-8-16-9-7-14(13)17-18(15)11-12-4-2-1-3-5-12/h1-5,10,16H,6-9,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor transfected in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532830 (CHEMBL4438673) Show SMILES Fc1ccc(Cc2cc3CCNCCc3nn2)cc1 Show InChI InChI=1S/C15H16FN3/c16-13-3-1-11(2-4-13)9-14-10-12-5-7-17-8-6-15(12)19-18-14/h1-4,10,17H,5-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor transfected in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532831 (CHEMBL4463588) Show SMILES Clc1ccccc1Cc1cc2CCNCCc2nn1 Show InChI InChI=1S/C15H16ClN3/c16-14-4-2-1-3-11(14)9-13-10-12-5-7-17-8-6-15(12)19-18-13/h1-4,10,17H,5-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	310	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor transfected in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532827 (CHEMBL4571641) Show SMILES Clc1ccc(Cc2cc3CCNCCc3nn2)cc1 Show InChI InChI=1S/C15H16ClN3/c16-13-3-1-11(2-4-13)9-14-10-12-5-7-17-8-6-15(12)19-18-14/h1-4,10,17H,5-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	310	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor transfected in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301288 (2-benzyl-2,4,5,6,7,8-hexahydropyrazolo[4,3-d]azepi...) Show SMILES C(c1ccccc1)n1cc2CCNCCc2n1 Show InChI InChI=1S/C14H17N3/c1-2-4-12(5-3-1)10-17-11-13-6-8-15-9-7-14(13)16-17/h1-5,11,15H,6-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.98E+3	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor transfected in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301285 (1-benzyl-1,2,5,6,7,8-hexahydropyrazolo[4,3-d]azepi...) Show SMILES O=c1[nH]n(Cc2ccccc2)c2CCNCCc12 Show InChI InChI=1S/C14H17N3O/c18-14-12-6-8-15-9-7-13(12)17(16-14)10-11-4-2-1-3-5-11/h1-5,15H,6-10H2,(H,16,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor transfected in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301289 (1-benzyl-1,4,5,6,7,8-hexahydropyrazolo[4,3-d]azepi...) Show SMILES C(c1ccccc1)n1ncc2CCNCCc12 Show InChI InChI=1S/C14H17N3/c1-2-4-12(5-3-1)11-17-14-7-9-15-8-6-13(14)10-16-17/h1-5,10,15H,6-9,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor transfected in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50301297 (2-benzyl-6,7,8,9-tetrahydro-2H-pyridazino[4,3-d]az...) Show SMILES O=c1cc2CCNCCc2nn1Cc1ccccc1 Show InChI InChI=1S/C15H17N3O/c19-15-10-13-6-8-16-9-7-14(13)17-18(15)11-12-4-2-1-3-5-12/h1-5,10,16H,6-9,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	360	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2B receptor transfected in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50532831 (CHEMBL4463588) Show SMILES Clc1ccccc1Cc1cc2CCNCCc2nn1 Show InChI InChI=1S/C15H16ClN3/c16-14-4-2-1-3-11(14)9-13-10-12-5-7-17-8-6-15(12)19-18-13/h1-4,10,17H,5-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	800	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2B receptor transfected in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50532824 (CHEMBL4538660) Show SMILES FC(F)(F)c1cccc(Cc2cc3CCNCCc3nn2)c1 Show InChI InChI=1S/C16H16F3N3/c17-16(18,19)13-3-1-2-11(8-13)9-14-10-12-4-6-20-7-5-15(12)22-21-14/h1-3,8,10,20H,4-7,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	450	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2B receptor transfected in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532832 (CHEMBL4514905) Show SMILES Cc1c(Cc2ccccc2)nnc2CCNCCc12 Show InChI InChI=1S/C16H19N3/c1-12-14-7-9-17-10-8-15(14)18-19-16(12)11-13-5-3-2-4-6-13/h2-6,17H,7-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	220	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor transfected in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532825 (CHEMBL4437696) Show SMILES CC(c1ccccc1)c1cc2CCNCCc2nn1 Show InChI InChI=1S/C16H19N3/c1-12(13-5-3-2-4-6-13)16-11-14-7-9-17-10-8-15(14)18-19-16/h2-6,11-12,17H,7-10H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor transfected in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532826 (CHEMBL4450290) Show SMILES COc1ccccc1Cc1cc2CCNCCc2nn1 Show InChI InChI=1S/C16H19N3O/c1-20-16-5-3-2-4-13(16)11-14-10-12-6-8-17-9-7-15(12)19-18-14/h2-5,10,17H,6-9,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor transfected in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532831 (CHEMBL4463588) Show SMILES Clc1ccccc1Cc1cc2CCNCCc2nn1 Show InChI InChI=1S/C15H16ClN3/c16-14-4-2-1-3-11(14)9-13-10-12-5-7-17-8-6-15(12)19-18-13/h1-4,10,17H,5-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	310	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor transfected in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301286 (2-benzyl-1,2,5,6,7,8-hexahydropyrazolo[4,3-d]azepi...) Show SMILES O=c1c2CCNCCc2[nH]n1Cc1ccccc1 Show InChI InChI=1S/C14H17N3O/c18-14-12-6-8-15-9-7-13(12)16-17(14)10-11-4-2-1-3-5-11/h1-5,15-16H,6-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor transfected in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301285 (1-benzyl-1,2,5,6,7,8-hexahydropyrazolo[4,3-d]azepi...) Show SMILES O=c1[nH]n(Cc2ccccc2)c2CCNCCc12 Show InChI InChI=1S/C14H17N3O/c18-14-12-6-8-15-9-7-13(12)17(16-14)10-11-4-2-1-3-5-11/h1-5,15H,6-10H2,(H,16,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor transfected in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532823 (CHEMBL4476743) Show SMILES C(c1nnc2CCNCCn12)c1ccccc1 Show InChI InChI=1S/C13H16N4/c1-2-4-11(5-3-1)10-13-16-15-12-6-7-14-8-9-17(12)13/h1-5,14H,6-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor transfected in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50532829 (CHEMBL4571336) Show SMILES O=c1[nH]c2CCNCCc2nc1Cc1ccccc1 Show InChI InChI=1S/C15H17N3O/c19-15-14(10-11-4-2-1-3-5-11)17-12-6-8-16-9-7-13(12)18-15/h1-5,16H,6-10H2,(H,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor transfected in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50301297 (2-benzyl-6,7,8,9-tetrahydro-2H-pyridazino[4,3-d]az...) Show SMILES O=c1cc2CCNCCc2nn1Cc1ccccc1 Show InChI InChI=1S/C15H17N3O/c19-15-10-13-6-8-16-9-7-14(13)17-18(15)11-12-4-2-1-3-5-12/h1-5,10,16H,6-9,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	360	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2B receptor transfected in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 26: 4117-21 (2016) Article DOI: 10.1016/j.bmcl.2016.06.060 BindingDB Entry DOI: 10.7270/Q2H998P2
					More data for this Ligand-Target Pair

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