Compile Data Set for Download or QSAR

Found 86 hits Enz. Inhib. hit(s) with all data for entry = 50010204   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238707 (US9394297, 371) Show SMILES Cc1nc2ccc(F)c(-c3cc4c(cc[nH]c4=O)[nH]3)c2nc1NC(C)(C)C Show InChI InChI=1S/C20H20FN5O/c1-10-18(26-20(2,3)4)25-17-14(23-10)6-5-12(21)16(17)15-9-11-13(24-15)7-8-22-19(11)27/h5-9,24H,1-4H3,(H,22,27)(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-2 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM238724 (US9394297, 405) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1c(F)ccc2c1nc(NC(C)(C)C)n(C)c2=O Show InChI InChI=1S/C20H22FN5O2/c1-9-15-11(17(27)22-9)8-13(23-15)14-12(21)7-6-10-16(14)24-19(25-20(2,3)4)26(5)18(10)28/h6-9,23H,1-5H3,(H,22,27)(H,24,25)/t9-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-1 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238724 (US9394297, 405) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1c(F)ccc2c1nc(NC(C)(C)C)n(C)c2=O Show InChI InChI=1S/C20H22FN5O2/c1-9-15-11(17(27)22-9)8-13(23-15)14-12(21)7-6-10-16(14)24-19(25-20(2,3)4)26(5)18(10)28/h6-9,23H,1-5H3,(H,22,27)(H,24,25)/t9-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-2 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM238637 (US9394297, 297) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1c(F)ccc2nc(C)c(NC(C)(C)C)nc12 Show InChI InChI=1S/C20H22FN5O/c1-9-16-11(19(27)23-9)8-14(24-16)15-12(21)6-7-13-17(15)25-18(10(2)22-13)26-20(3,4)5/h6-9,24H,1-5H3,(H,23,27)(H,25,26)/t9-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-1 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238637 (US9394297, 297) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1c(F)ccc2nc(C)c(NC(C)(C)C)nc12 Show InChI InChI=1S/C20H22FN5O/c1-9-16-11(19(27)23-9)8-14(24-16)15-12(21)6-7-13-17(15)25-18(10(2)22-13)26-20(3,4)5/h6-9,24H,1-5H3,(H,23,27)(H,25,26)/t9-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-2 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM238707 (US9394297, 371) Show SMILES Cc1nc2ccc(F)c(-c3cc4c(cc[nH]c4=O)[nH]3)c2nc1NC(C)(C)C Show InChI InChI=1S/C20H20FN5O/c1-10-18(26-20(2,3)4)25-17-14(23-10)6-5-12(21)16(17)15-9-11-13(24-15)7-8-22-19(11)27/h5-9,24H,1-4H3,(H,22,27)(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-1 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238766 (US9394297, 450) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(C)c2=O Show InChI InChI=1S/C20H23N5O2/c1-10-15-13(17(26)21-10)9-14(22-15)11-7-6-8-12-16(11)23-19(24-20(2,3)4)25(5)18(12)27/h6-10,22H,1-5H3,(H,21,26)(H,23,24)/t10-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-2 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM238767 (US9394297, 451) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC1(C)CC1)n(C)c2=O Show InChI InChI=1S/C20H21N5O2/c1-10-15-13(17(26)21-10)9-14(22-15)11-5-4-6-12-16(11)23-19(25(3)18(12)27)24-20(2)7-8-20/h4-6,9-10,22H,7-8H2,1-3H3,(H,21,26)(H,23,24)/t10-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-1 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50536094 (CHEMBL4541192) Show SMILES Cc1nc2cccc(-c3cc4C(=O)N[C@H](CCN)c4[nH]3)c2nc1NC(C)(C)C |r| Show InChI InChI=1S/C21H26N6O/c1-11-19(27-21(2,3)4)26-17-12(6-5-7-14(17)23-11)16-10-13-18(24-16)15(8-9-22)25-20(13)28/h5-7,10,15,24H,8-9,22H2,1-4H3,(H,25,28)(H,26,27)/t15-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-2 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50536095 (CHEMBL4587596) Show SMILES Cc1nc2ccc(F)c(-c3cc4c(CCNC4=O)[nH]3)c2nc1NC(C)(C)C Show InChI InChI=1S/C20H22FN5O/c1-10-18(26-20(2,3)4)25-17-14(23-10)6-5-12(21)16(17)15-9-11-13(24-15)7-8-22-19(11)27/h5-6,9,24H,7-8H2,1-4H3,(H,22,27)(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-2 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50536095 (CHEMBL4587596) Show SMILES Cc1nc2ccc(F)c(-c3cc4c(CCNC4=O)[nH]3)c2nc1NC(C)(C)C Show InChI InChI=1S/C20H22FN5O/c1-10-18(26-20(2,3)4)25-17-14(23-10)6-5-12(21)16(17)15-9-11-13(24-15)7-8-22-19(11)27/h5-6,9,24H,7-8H2,1-4H3,(H,22,27)(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-1 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238706 (US9394297, 370) Show SMILES Cc1nc2ccc(F)c(-c3cc4c(CCNC4=O)[nH]3)c2nc1NC(C)(C)CO Show InChI InChI=1S/C20H22FN5O2/c1-10-18(26-20(2,3)9-27)25-17-14(23-10)5-4-12(21)16(17)15-8-11-13(24-15)6-7-22-19(11)28/h4-5,8,24,27H,6-7,9H2,1-3H3,(H,22,28)(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-2 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM238766 (US9394297, 450) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(C)c2=O Show InChI InChI=1S/C20H23N5O2/c1-10-15-13(17(26)21-10)9-14(22-15)11-7-6-8-12-16(11)23-19(24-20(2,3)4)25(5)18(12)27/h6-10,22H,1-5H3,(H,21,26)(H,23,24)/t10-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-1 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM238662 (US9394297, 324) Show SMILES Cc1nc2cccc(-c3cc4C(=O)NC5(CC5)c4[nH]3)c2nc1NC(C)(C)C Show InChI InChI=1S/C21H23N5O/c1-11-18(25-20(2,3)4)24-16-12(6-5-7-14(16)22-11)15-10-13-17(23-15)21(8-9-21)26-19(13)27/h5-7,10,23H,8-9H2,1-4H3,(H,24,25)(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-1 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238767 (US9394297, 451) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC1(C)CC1)n(C)c2=O Show InChI InChI=1S/C20H21N5O2/c1-10-15-13(17(26)21-10)9-14(22-15)11-5-4-6-12-16(11)23-19(25(3)18(12)27)24-20(2)7-8-20/h4-6,9-10,22H,7-8H2,1-3H3,(H,21,26)(H,23,24)/t10-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-2 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238662 (US9394297, 324) Show SMILES Cc1nc2cccc(-c3cc4C(=O)NC5(CC5)c4[nH]3)c2nc1NC(C)(C)C Show InChI InChI=1S/C21H23N5O/c1-11-18(25-20(2,3)4)24-16-12(6-5-7-14(16)22-11)15-10-13-17(23-15)21(8-9-21)26-19(13)27/h5-7,10,23H,8-9H2,1-4H3,(H,24,25)(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-2 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM238771 (US9394297, 455) Show SMILES C[C@H]1NC(=O)c2c(Cl)c([nH]c12)-c1cccc2nc(C)c(NC(C)(C)C)nc12 Show InChI InChI=1S/C20H22ClN5O/c1-9-15-13(19(27)23-9)14(21)17(24-15)11-7-6-8-12-16(11)25-18(10(2)22-12)26-20(3,4)5/h6-9,24H,1-5H3,(H,23,27)(H,25,26)/t9-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-1 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50536097 (CHEMBL4572195) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(N1CCCC1(C)C)n(C)c2=O |r| Show InChI InChI=1S/C22H25N5O2/c1-12-17-15(19(28)23-12)11-16(24-17)13-7-5-8-14-18(13)25-21(26(4)20(14)29)27-10-6-9-22(27,2)3/h5,7-8,11-12,24H,6,9-10H2,1-4H3,(H,23,28)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-2 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50536094 (CHEMBL4541192) Show SMILES Cc1nc2cccc(-c3cc4C(=O)N[C@H](CCN)c4[nH]3)c2nc1NC(C)(C)C |r| Show InChI InChI=1S/C21H26N6O/c1-11-19(27-21(2,3)4)26-17-12(6-5-7-14(17)23-11)16-10-13-18(24-16)15(8-9-22)25-20(13)28/h5-7,10,15,24H,8-9,22H2,1-4H3,(H,25,28)(H,26,27)/t15-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-1 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238547 (US9394297, 193) Show SMILES Cc1nc2cccc(-c3cc4c(CCNC4=O)[nH]3)c2nc1NC(C)(C)C Show InChI InChI=1S/C20H23N5O/c1-11-18(25-20(2,3)4)24-17-12(6-5-7-15(17)22-11)16-10-13-14(23-16)8-9-21-19(13)26/h5-7,10,23H,8-9H2,1-4H3,(H,21,26)(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-2 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM238664 (US9394297, 326) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2nc(C)c(NC(C)(C)C)nc12 Show InChI InChI=1S/C20H23N5O/c1-10-16-13(19(26)22-10)9-15(23-16)12-7-6-8-14-17(12)24-18(11(2)21-14)25-20(3,4)5/h6-10,23H,1-5H3,(H,22,26)(H,24,25)/t10-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-1 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50536098 (CHEMBL4587256) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)CO)n(C)c2=O |r| Show InChI InChI=1S/C20H23N5O3/c1-10-15-13(17(27)21-10)8-14(22-15)11-6-5-7-12-16(11)23-19(25(4)18(12)28)24-20(2,3)9-26/h5-8,10,22,26H,9H2,1-4H3,(H,21,27)(H,23,24)/t10-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-1 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM238547 (US9394297, 193) Show SMILES Cc1nc2cccc(-c3cc4c(CCNC4=O)[nH]3)c2nc1NC(C)(C)C Show InChI InChI=1S/C20H23N5O/c1-11-18(25-20(2,3)4)24-17-12(6-5-7-15(17)22-11)16-10-13-14(23-16)8-9-21-19(13)26/h5-7,10,23H,8-9H2,1-4H3,(H,21,26)(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-1 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50536097 (CHEMBL4572195) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(N1CCCC1(C)C)n(C)c2=O |r| Show InChI InChI=1S/C22H25N5O2/c1-12-17-15(19(28)23-12)11-16(24-17)13-7-5-8-14-18(13)25-21(26(4)20(14)29)27-10-6-9-22(27,2)3/h5,7-8,11-12,24H,6,9-10H2,1-4H3,(H,23,28)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-1 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238672 (US9394297, 334) Show SMILES Cc1nc2cccc(-c3cc4C(=O)NCc4[nH]3)c2nc1NC(C)(C)C Show InChI InChI=1S/C19H21N5O/c1-10-17(24-19(2,3)4)23-16-11(6-5-7-13(16)21-10)14-8-12-15(22-14)9-20-18(12)25/h5-8,22H,9H2,1-4H3,(H,20,25)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-2 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50536098 (CHEMBL4587256) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)CO)n(C)c2=O |r| Show InChI InChI=1S/C20H23N5O3/c1-10-15-13(17(27)21-10)8-14(22-15)11-6-5-7-12-16(11)23-19(25(4)18(12)28)24-20(2,3)9-26/h5-8,10,22,26H,9H2,1-4H3,(H,21,27)(H,23,24)/t10-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-2 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM238706 (US9394297, 370) Show SMILES Cc1nc2ccc(F)c(-c3cc4c(CCNC4=O)[nH]3)c2nc1NC(C)(C)CO Show InChI InChI=1S/C20H22FN5O2/c1-10-18(26-20(2,3)9-27)25-17-14(23-10)5-4-12(21)16(17)15-8-11-13(24-15)6-7-22-19(11)28/h4-5,8,24,27H,6-7,9H2,1-3H3,(H,22,28)(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-1 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238771 (US9394297, 455) Show SMILES C[C@H]1NC(=O)c2c(Cl)c([nH]c12)-c1cccc2nc(C)c(NC(C)(C)C)nc12 Show InChI InChI=1S/C20H22ClN5O/c1-9-15-13(19(27)23-9)14(21)17(24-15)11-7-6-8-12-16(11)25-18(10(2)22-12)26-20(3,4)5/h6-9,24H,1-5H3,(H,23,27)(H,25,26)/t9-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-2 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238664 (US9394297, 326) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2nc(C)c(NC(C)(C)C)nc12 Show InChI InChI=1S/C20H23N5O/c1-10-16-13(19(26)22-10)9-15(23-16)12-7-6-8-14-17(12)24-18(11(2)21-14)25-20(3,4)5/h6-10,23H,1-5H3,(H,22,26)(H,24,25)/t10-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-2 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50536092 (CHEMBL4589855) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(N(C)C(C)(C)C)n(C)c2=O |r| Show InChI InChI=1S/C21H25N5O2/c1-11-16-14(18(27)22-11)10-15(23-16)12-8-7-9-13-17(12)24-20(25(5)19(13)28)26(6)21(2,3)4/h7-11,23H,1-6H3,(H,22,27)/t11-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-2 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM238672 (US9394297, 334) Show SMILES Cc1nc2cccc(-c3cc4C(=O)NCc4[nH]3)c2nc1NC(C)(C)C Show InChI InChI=1S/C19H21N5O/c1-10-17(24-19(2,3)4)23-16-11(6-5-7-13(16)21-10)14-8-12-15(22-14)9-20-18(12)25/h5-8,22H,9H2,1-4H3,(H,20,25)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-1 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50536092 (CHEMBL4589855) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(N(C)C(C)(C)C)n(C)c2=O |r| Show InChI InChI=1S/C21H25N5O2/c1-11-16-14(18(27)22-11)10-15(23-16)12-8-7-9-13-17(12)24-20(25(5)19(13)28)26(6)21(2,3)4/h7-11,23H,1-6H3,(H,22,27)/t11-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-1 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM238665 (US9394297, 327) Show SMILES C[C@@H]1NC(=O)c2cc([nH]c12)-c1cccc2nc(C)c(NC(C)(C)C)nc12 Show InChI InChI=1S/C20H23N5O/c1-10-16-13(19(26)22-10)9-15(23-16)12-7-6-8-14-17(12)24-18(11(2)21-14)25-20(3,4)5/h6-10,23H,1-5H3,(H,22,26)(H,24,25)/t10-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-1 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238665 (US9394297, 327) Show SMILES C[C@@H]1NC(=O)c2cc([nH]c12)-c1cccc2nc(C)c(NC(C)(C)C)nc12 Show InChI InChI=1S/C20H23N5O/c1-10-16-13(19(26)22-10)9-15(23-16)12-7-6-8-14-17(12)24-18(11(2)21-14)25-20(3,4)5/h6-10,23H,1-5H3,(H,22,26)(H,24,25)/t10-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-2 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50536100 (CHEMBL4522524) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccn2c1nc(NC(C)(C)C)c(C)c2=O |r| Show InChI InChI=1S/C20H23N5O2/c1-10-16(24-20(3,4)5)23-17-12(7-6-8-25(17)19(10)27)14-9-13-15(22-14)11(2)21-18(13)26/h6-9,11,22,24H,1-5H3,(H,21,26)/t11-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-2 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50536091 (CHEMBL4527131) Show SMILES Cc1nc2cccc(-c3cc4CNC(=O)c4s3)c2nc1NC(C)(C)C Show InChI InChI=1S/C19H20N4OS/c1-10-17(23-19(2,3)4)22-15-12(6-5-7-13(15)21-10)14-8-11-9-20-18(24)16(11)25-14/h5-8H,9H2,1-4H3,(H,20,24)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-2 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50536091 (CHEMBL4527131) Show SMILES Cc1nc2cccc(-c3cc4CNC(=O)c4s3)c2nc1NC(C)(C)C Show InChI InChI=1S/C19H20N4OS/c1-10-17(23-19(2,3)4)22-15-12(6-5-7-13(15)21-10)14-8-11-9-20-18(24)16(11)25-14/h5-8H,9H2,1-4H3,(H,20,24)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-1 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM238645 (US9394297, 305) Show SMILES Cc1nc2cccc(-c3cc4c(CCCNC4=O)[nH]3)c2nc1NC(C)(C)C Show InChI InChI=1S/C21H25N5O/c1-12-19(26-21(2,3)4)25-18-13(7-5-8-16(18)23-12)17-11-14-15(24-17)9-6-10-22-20(14)27/h5,7-8,11,24H,6,9-10H2,1-4H3,(H,22,27)(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-1 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50536100 (CHEMBL4522524) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccn2c1nc(NC(C)(C)C)c(C)c2=O |r| Show InChI InChI=1S/C20H23N5O2/c1-10-16(24-20(3,4)5)23-17-12(7-6-8-25(17)19(10)27)14-9-13-15(22-14)11(2)21-18(13)26/h6-9,11,22,24H,1-5H3,(H,21,26)/t11-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-1 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50536096 (CHEMBL4530924) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1nccc2c1nc(NC(C)(C)C)n(C)c2=O |r| Show InChI InChI=1S/C19H22N6O2/c1-9-13-11(16(26)21-9)8-12(22-13)15-14-10(6-7-20-15)17(27)25(5)18(23-14)24-19(2,3)4/h6-9,22H,1-5H3,(H,21,26)(H,23,24)/t9-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-1 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50536090 (CHEMBL4559238) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(CC(C)(C)C)n(C)c2=O |r| Show InChI InChI=1S/C21H24N4O2/c1-11-17-14(19(26)22-11)9-15(23-17)12-7-6-8-13-18(12)24-16(10-21(2,3)4)25(5)20(13)27/h6-9,11,23H,10H2,1-5H3,(H,22,26)/t11-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-2 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50536099 (CHEMBL4546373) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1N=C(NC(C)(C)C)N(C)S2(=O)=O |r,t:19| Show InChI InChI=1S/C19H23N5O3S/c1-10-15-12(17(25)20-10)9-13(21-15)11-7-6-8-14-16(11)22-18(23-19(2,3)4)24(5)28(14,26)27/h6-10,21H,1-5H3,(H,20,25)(H,22,23)/t10-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-2 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238534 (US9394297, 174) Show SMILES Cc1nc2cccc(-c3cc4C(=O)NCCn4c3)c2nc1NC(C)(C)C Show InChI InChI=1S/C20H23N5O/c1-12-18(24-20(2,3)4)23-17-14(6-5-7-15(17)22-12)13-10-16-19(26)21-8-9-25(16)11-13/h5-7,10-11H,8-9H2,1-4H3,(H,21,26)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-2 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50536093 (CHEMBL4514782) Show SMILES Cc1nc2cccc(-c3cc4C(=O)NCc4s3)c2nc1NC(C)(C)C Show InChI InChI=1S/C19H20N4OS/c1-10-17(23-19(2,3)4)22-16-11(6-5-7-13(16)21-10)14-8-12-15(25-14)9-20-18(12)24/h5-8H,9H2,1-4H3,(H,20,24)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-1 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50536099 (CHEMBL4546373) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1N=C(NC(C)(C)C)N(C)S2(=O)=O |r,t:19| Show InChI InChI=1S/C19H23N5O3S/c1-10-15-12(17(25)20-10)9-13(21-15)11-7-6-8-14-16(11)22-18(23-19(2,3)4)24(5)28(14,26)27/h6-10,21H,1-5H3,(H,20,25)(H,22,23)/t10-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-1 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM238534 (US9394297, 174) Show SMILES Cc1nc2cccc(-c3cc4C(=O)NCCn4c3)c2nc1NC(C)(C)C Show InChI InChI=1S/C20H23N5O/c1-12-18(24-20(2,3)4)23-17-14(6-5-7-15(17)22-12)13-10-16-19(26)21-8-9-25(16)11-13/h5-7,10-11H,8-9H2,1-4H3,(H,21,26)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-1 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50536093 (CHEMBL4514782) Show SMILES Cc1nc2cccc(-c3cc4C(=O)NCc4s3)c2nc1NC(C)(C)C Show InChI InChI=1S/C19H20N4OS/c1-10-17(23-19(2,3)4)22-16-11(6-5-7-13(16)21-10)14-8-12-15(25-14)9-20-18(12)24/h5-8H,9H2,1-4H3,(H,20,24)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-2 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50536090 (CHEMBL4559238) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(CC(C)(C)C)n(C)c2=O |r| Show InChI InChI=1S/C21H24N4O2/c1-11-17-14(19(26)22-11)9-15(23-17)12-7-6-8-13-18(12)24-16(10-21(2,3)4)25(5)20(13)27/h6-9,11,23H,10H2,1-5H3,(H,22,26)/t11-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-1 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50536096 (CHEMBL4530924) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1nccc2c1nc(NC(C)(C)C)n(C)c2=O |r| Show InChI InChI=1S/C19H22N6O2/c1-9-13-11(16(26)21-9)8-12(22-13)15-14-10(6-7-20-15)17(27)25(5)18(23-14)24-19(2,3)4/h6-9,22H,1-5H3,(H,21,26)(H,23,24)/t9-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.40	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-2 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238645 (US9394297, 305) Show SMILES Cc1nc2cccc(-c3cc4c(CCCNC4=O)[nH]3)c2nc1NC(C)(C)C Show InChI InChI=1S/C21H25N5O/c1-12-19(26-21(2,3)4)25-18-13(7-5-8-16(18)23-12)17-11-14-15(24-17)9-6-10-22-20(14)27/h5,7-8,11,24H,6,9-10H2,1-4H3,(H,22,27)(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-2 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 86 total )  |  Next  |  Last  >>

Jump to: